Published in Expert Opin Ther Targets on May 01, 2010
Remodelling of Ca2+ transport in cancer: how it contributes to cancer hallmarks? Philos Trans R Soc Lond B Biol Sci (2014) 0.98
cAMP activates TRPC6 channels via the phosphatidylinositol 3-kinase (PI3K)-protein kinase B (PKB)-mitogen-activated protein kinase kinase (MEK)-ERK1/2 signaling pathway. J Biol Chem (2011) 0.92
New insights into pharmacological tools to TR(i)P cancer up. Br J Pharmacol (2014) 0.89
K(+) channels and cell cycle progression in tumor cells. Front Physiol (2013) 0.87
Phosphodiesterase 5 inhibition ameliorates angiontensin II-induced podocyte dysmotility via the protein kinase G-mediated downregulation of TRPC6 activity. Am J Physiol Renal Physiol (2014) 0.87
Expression of transient receptor potential channel 6 in cervical cancer. Onco Targets Ther (2012) 0.79
Store-Operated Calcium Channel Complex in Postsynaptic Spines: A New Therapeutic Target for Alzheimer's Disease Treatment. J Neurosci (2016) 0.76
Overexpression of Transient Receptor Protein Cation Channel Subfamily A Member 1, Confers an Independent Prognostic Indicator in Nasopharyngeal Carcinoma. J Cancer (2016) 0.76
Targeting calcium signaling in cancer therapy. Acta Pharm Sin B (2016) 0.75
Zinc transporters and dysregulated channels in cancers. Front Biosci (Landmark Ed) (2017) 0.75
Chromosome 1p and 11q deletions and outcome in neuroblastoma. N Engl J Med (2005) 4.92
Programmed death-1-induced interleukin-10 production by monocytes impairs CD4+ T cell activation during HIV infection. Nat Med (2010) 3.81
Structure-based prediction of protein-protein interactions on a genome-wide scale. Nature (2012) 3.37
Exome sequencing of hepatitis B virus-associated hepatocellular carcinoma. Nat Genet (2012) 3.14
Polysaccharide processing and presentation by the MHCII pathway. Cell (2004) 2.88
TRPC channels promote cerebellar granule neuron survival. Nat Neurosci (2007) 2.47
Global levels of histone modifications predict prognosis in different cancers. Am J Pathol (2009) 2.28
Convergence of TCR and cytokine signaling leads to FOXO3a phosphorylation and drives the survival of CD4+ central memory T cells. J Exp Med (2006) 2.27
Integrative genomics identifies LMO1 as a neuroblastoma oncogene. Nature (2010) 2.21
miR-34s inhibit osteoblast proliferation and differentiation in the mouse by targeting SATB2. J Cell Biol (2012) 2.15
Transcription factor FOXO3a controls the persistence of memory CD4(+) T cells during HIV infection. Nat Med (2008) 1.85
A stiffness switch in human immunodeficiency virus. Biophys J (2006) 1.64
Gelsolin regulates cardiac remodeling after myocardial infarction through DNase I-mediated apoptosis. Circ Res (2009) 1.63
Staphylococcus aureus strains that express serotype 5 or serotype 8 capsular polysaccharides differ in virulence. Infect Immun (2005) 1.62
CD11c expression in adipose tissue and blood and its role in diet-induced obesity. Arterioscler Thromb Vasc Biol (2009) 1.57
A SIRT1-LSD1 corepressor complex regulates Notch target gene expression and development. Mol Cell (2011) 1.55
Superficial angiomyxoma of the vulva complicated with condyloma acuminatum and Staphylococcus hominis infection. Int J Dermatol (2013) 1.54
Regulation of lipogenesis by cyclin-dependent kinase 8-mediated control of SREBP-1. J Clin Invest (2012) 1.52
A critical function of Th17 proinflammatory cells in the development of atherosclerotic plaque in mice. J Immunol (2010) 1.51
The H+-linked monocarboxylate transporter (MCT1/SLC16A1): a potential therapeutic target for high-risk neuroblastoma. Mol Pharmacol (2006) 1.49
Overactivation of glycogen synthase kinase-3 by inhibition of phosphoinositol-3 kinase and protein kinase C leads to hyperphosphorylation of tau and impairment of spatial memory. J Neurochem (2003) 1.47
Impact of tobacco use on the symptoms of painful temporomandibular joint disorders. Pain (2009) 1.45
Flt1 acts as a negative regulator of tip cell formation and branching morphogenesis in the zebrafish embryo. Development (2011) 1.44
Differential diagnosis between hepatic metastases and benign focal lesions using DWI with parallel acquisition technique: a meta-analysis. Tumour Biol (2014) 1.44
Video-assisted thoracic surgery versus open thoracotomy for non-small-cell lung cancer: a propensity score analysis based on a multi-institutional registry. Eur J Cardiothorac Surg (2013) 1.44
Clinical outcome of subcentimeter non-small cell lung cancer after surgical resection: single institution experience of 105 patients. J Surg Oncol (2014) 1.43
Baseline platelet count and clinical outcome in acute coronary syndrome. Circ J (2012) 1.42
Phosphorylation of tau antagonizes apoptosis by stabilizing beta-catenin, a mechanism involved in Alzheimer's neurodegeneration. Proc Natl Acad Sci U S A (2007) 1.41
Inhibition of glycogen synthase kinase-3beta protects dopaminergic neurons from MPTP toxicity. Neuropharmacology (2007) 1.41
Comparison of C₅₀ for Propofol-remifentanil Target-controlled Infusion and Bispectral Index at Loss of Consciousness and Response to Painful Stimulus in Elderly and Young Patients. Chin Med J (Engl) (2015) 1.40
Decision Aid for Cigarette Smokers Scheduled for Elective Surgery. Anesthesiology (2015) 1.38
Scaffolding by ERK3 regulates MK5 in development. EMBO J (2004) 1.36
Activation of glycogen synthase kinase-3 inhibits long-term potentiation with synapse-associated impairments. J Neurosci (2007) 1.35
Pulsatile shear and Gja5 modulate arterial identity and remodeling events during flow-driven arteriogenesis. Development (2010) 1.32
Essential role of TRPC6 channels in G2/M phase transition and development of human glioma. J Natl Cancer Inst (2010) 1.29
Assembly of 500,000 inter-specific catfish expressed sequence tags and large scale gene-associated marker development for whole genome association studies. Genome Biol (2010) 1.29
CD160 and PD-1 co-expression on HIV-specific CD8 T cells defines a subset with advanced dysfunction. PLoS Pathog (2012) 1.28
Injectable nano-network for glucose-mediated insulin delivery. ACS Nano (2013) 1.26
Blockade of Tim-3 signaling restores the virus-specific CD8⁺ T-cell response in patients with chronic hepatitis B. Eur J Immunol (2012) 1.25
Tau becomes a more favorable substrate for GSK-3 when it is prephosphorylated by PKA in rat brain. J Biol Chem (2004) 1.24
The tight junction protein CAR regulates cardiac conduction and cell-cell communication. J Exp Med (2008) 1.23
Resveratrol as a therapeutic agent for neurodegenerative diseases. Mol Neurobiol (2010) 1.23
Proliferation of human neuroblastomas mediated by the epidermal growth factor receptor. Cancer Res (2005) 1.23
Critical role of TRPC6 channels in the formation of excitatory synapses. Nat Neurosci (2008) 1.22
Frequent loss of PDCD4 expression in human glioma: possible role in the tumorigenesis of glioma. Oncol Rep (2007) 1.20
The role of the p38 MAPK signaling pathway in high glucose-induced epithelial-mesenchymal transition of cultured human renal tubular epithelial cells. PLoS One (2011) 1.20
Requirement of dendritic Akt degradation by the ubiquitin-proteasome system for neuronal polarity. J Cell Biol (2006) 1.20
A meta-analysis of candidate gene polymorphisms and ischemic stroke in 6 study populations: association of lymphotoxin-alpha in nonhypertensive patients. Stroke (2009) 1.20
The effects of depression and smoking on pain severity and opioid use in patients with chronic pain. Pain (2010) 1.19
Coevolution of RANTES sensitivity and mode of CCR5 receptor use by human immunodeficiency virus type 1 of the R5 phenotype. J Virol (2004) 1.17
Accurate outcome prediction in neuroblastoma across independent data sets using a multigene signature. Clin Cancer Res (2010) 1.15
Retracted Curcumin prevents and reverses murine cardiac hypertrophy. J Clin Invest (2008) 1.15
Identification of broadly protective human antibodies to Pseudomonas aeruginosa exopolysaccharide Psl by phenotypic screening. J Exp Med (2012) 1.15
Effect of exogenous spermidine on polyamine content and metabolism in tomato exposed to salinity-alkalinity mixed stress. Plant Physiol Biochem (2012) 1.15
Canonical transient receptor potential 3 channels regulate mitochondrial calcium uptake. Proc Natl Acad Sci U S A (2013) 1.14
Telocytes in human oesophagus. J Cell Mol Med (2013) 1.14
Critical role of TRPC6 channels in VEGF-mediated angiogenesis. Cancer Lett (2009) 1.12
Botanical phenolics and brain health. Neuromolecular Med (2008) 1.11
Polyphenols in cerebral ischemia: novel targets for neuroprotection. Mol Neurobiol (2005) 1.11
Mitochondrial DNA oxidative damage triggering mitochondrial dysfunction and apoptosis in high glucose-induced HRECs. Invest Ophthalmol Vis Sci (2008) 1.11
The critical role of CD133(+)CD44(+/high) tumor cells in hematogenous metastasis of liver cancers. Cell Res (2011) 1.10
Epidemiology and molecular characteristics of community-associated methicillin-resistant and methicillin-susceptible Staphylococcus aureus from skin/soft tissue infections in a children's hospital in Beijing, China. Diagn Microbiol Infect Dis (2010) 1.09
Perceptions of tobacco advertising and marketing that might lead to smoking initiation among Chinese high school girls. Tob Control (2007) 1.08
TRPC6 channels promote dendritic growth via the CaMKIV-CREB pathway. J Cell Sci (2008) 1.07
Induction of secretory phospholipase A2 in reactive astrocytes in response to transient focal cerebral ischemia in the rat brain. J Neurochem (2004) 1.07
Long-term but not short-term blockade of dopamine release in Drosophila impairs orientation during flight in a visual attention paradigm. Eur J Neurosci (2004) 1.07
Dll4-Notch signaling determines the formation of native arterial collateral networks and arterial function in mouse ischemia models. Development (2013) 1.07
COX-2 from the injury milieu is critical for the initiation of periosteal progenitor cell mediated bone healing. Bone (2008) 1.07
Prognostic role of Twist, Slug, and Foxc2 expression in stage I non-small-cell lung cancer after curative resection. Clin Lung Cancer (2011) 1.06
Burden of pneumonia and meningitis caused by Streptococcus pneumoniae in China among children under 5 years of age: a systematic literature review. PLoS One (2011) 1.05
Blockade of TRPC6 channels induced G2/M phase arrest and suppressed growth in human gastric cancer cells. Int J Cancer (2009) 1.04
Metabolomic study for diagnostic model of oesophageal cancer using gas chromatography/mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci (2009) 1.04
Transcriptome profiling of testis during sexual maturation stages in Eriocheir sinensis using Illumina sequencing. PLoS One (2012) 1.04
E2F8 contributes to human hepatocellular carcinoma via regulating cell proliferation. Cancer Res (2010) 1.03
Profound metabolic, functional, and cytolytic differences characterize HIV-specific CD8 T cells in primary and chronic HIV infection. Blood (2012) 1.03
Primary pulmonary mucoepidermoid carcinoma: an analysis of 21 cases. World J Surg Oncol (2012) 1.03
The unique expression profile of human TIPE2 suggests new functions beyond its role in immune regulation. Mol Immunol (2011) 1.02
Multifunctional nanoparticles for targeted delivery of immune activating and cancer therapeutic agents. J Control Release (2013) 1.01
PDCD4 gene silencing in gliomas is associated with 5'CpG island methylation and unfavourable prognosis. J Cell Mol Med (2009) 1.01
Hydrogen sulfide preconditioning or neutrophil depletion attenuates ischemia-reperfusion-induced mitochondrial dysfunction in rat small intestine. Am J Physiol Gastrointest Liver Physiol (2011) 1.01
Human tumor necrosis factor (TNF)-alpha-induced protein 8-like 2 suppresses hepatocellular carcinoma metastasis through inhibiting Rac1. Mol Cancer (2013) 1.01
Characterization of the steric defense of the HIV-1 gp41 N-trimer region. Protein Sci (2008) 1.01
Homocysteine induces tau phosphorylation by inactivating protein phosphatase 2A in rat hippocampus. Neurobiol Aging (2007) 1.00
Opposing roles for ATF2 and c-Fos in c-Jun-mediated neuronal apoptosis. Mol Cell Biol (2009) 1.00
HIV biological variability unveiled: frequent isolations and chimeric receptors reveal unprecedented variation of coreceptor use. AIDS (2003) 1.00
Platinum anticancer drug damage enforces a particular rotational setting of DNA in nucleosomes. Proc Natl Acad Sci U S A (2005) 1.00
Extensive mediastinal lymphadenectomy during minimally invasive esophagectomy: optimal results from a single center. J Gastrointest Surg (2012) 0.99
GSK-3 beta inhibits presynaptic vesicle exocytosis by phosphorylating P/Q-type calcium channel and interrupting SNARE complex formation. J Neurosci (2010) 0.99
Smoking cessation and chronic pain: patient and pain medicine physician attitudes. Pain Pract (2011) 0.98
Transient activation of EGFR/AKT cell survival pathway and expression of survivin contribute to reduced sensitivity of human melanoma cells to betulinic acid. Int J Oncol (2005) 0.98
Role of magnetic resonance spectroscopy for the differentiation of recurrent glioma from radiation necrosis: a systematic review and meta-analysis. Eur J Radiol (2014) 0.98
Clinician-delivered intervention to facilitate tobacco quitline use by surgical patients. Anesthesiology (2011) 0.98
Structural and functional multiplicity of the kisspeptin/GPR54 system in goldfish (Carassius auratus). J Endocrinol (2009) 0.97
Survival and cardiac remodeling after myocardial infarction are critically dependent on the host innate immune interleukin-1 receptor-associated kinase-4 signaling: a regulator of bone marrow-derived dendritic cells. Circulation (2009) 0.97
IL-17 induces apoptosis of vascular endothelial cells: a potential mechanism for human acute coronary syndrome. Clin Immunol (2011) 0.97
Comparative transcriptome analysis of the accessory sex gland and testis from the Chinese mitten crab (Eriocheir sinensis). PLoS One (2013) 0.96
mTORC2 signaling promotes skeletal growth and bone formation in mice. J Bone Miner Res (2015) 0.96