Published in Nature on January 26, 1978
Selective protection of stereospecific enkephalin and opiate binding against inactivation by N-ethylmaleimide: evidence for two classes of opiate receptors. Proc Natl Acad Sci U S A (1980) 1.04
Purification and characterization of the mu opiate receptor from rat brain using affinity chromatography. Proc Natl Acad Sci U S A (1985) 0.88
Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo. Oncogene (1994) 7.24
Stereospecific binding of the potent narcotic analgesic (3H) Etorphine to rat-brain homogenate. Proc Natl Acad Sci U S A (1973) 3.91
Structural model for the beta-amyloid fibril based on interstrand alignment of an antiparallel-sheet comprising a C-terminal peptide. Nat Struct Biol (1995) 3.44
From HER2/Neu signal cascade to androgen receptor and its coactivators: a novel pathway by induction of androgen target genes through MAP kinase in prostate cancer cells. Proc Natl Acad Sci U S A (1999) 3.00
The relation between intercellular coupling and electrical noise in turtle photoreceptors. J Physiol (1976) 2.76
Colour-dependence of cone responses in the turtle retina. J Physiol (1973) 2.71
Immediate early up-regulation of bax expression by p53 but not TGF beta 1: a paradigm for distinct apoptotic pathways. Oncogene (1994) 2.49
Analysis of electrical noise in turtle cones. J Physiol (1977) 2.38
Two types of luminosity horizontal cells in the retina of the turtle. J Physiol (1973) 2.31
Spontaneous voltage fluctuations in retinal cones and bipolar cells. Nature (1975) 2.05
Slow- and tight-binding inhibitors of the 85-kDa human phospholipase A2. Biochemistry (1993) 1.93
Differential effects of cholesterol and lanosterol on artificial membranes. Proc Natl Acad Sci U S A (1977) 1.89
Further properties of stereospecific opiate binding sites in rat brain: on the nature of the sodium effect. J Pharmacol Exp Ther (1975) 1.68
The novel primary response gene MyD118 and the proto-oncogenes myb, myc, and bcl-2 modulate transforming growth factor beta 1-induced apoptosis of myeloid leukemia cells. Mol Cell Biol (1994) 1.58
Interactions leading to horizontal cell responses in the turtle retina. J Physiol (1974) 1.41
Increase of androgen-induced cell death and androgen receptor transactivation by BRCA1 in prostate cancer cells. Proc Natl Acad Sci U S A (2000) 1.36
Distribution of stereospecific binding of the potent narcotic analgesic etorphine in the human brain: predominance in the limbic system. Res Commun Chem Pathol Pharmacol (1973) 1.36
Polyamines and inhibition of RNA synthesis in E. coli by levorphanol. Biochem Biophys Res Commun (1966) 1.34
Evidence from opiate binding studies that heroin acts through its metabolites. Life Sci (1983) 1.30
Studies on the intracellular distribution and tissue binding of dihydromorphine-7,8-H3 in the rat. Proc Soc Exp Biol Med (1966) 1.30
Tight binding inhibitors of 85-kDa phospholipase A2 but not 14-kDa phospholipase A2 inhibit release of free arachidonate in thrombin-stimulated human platelets. J Biol Chem (1994) 1.29
Coupling of a new, active morphine derivative to sepharose for affinity chromatography. Proc Natl Acad Sci U S A (1972) 1.29
Effects of levorphanol on phospholipid metabolism and composition in Escherichia coli. Biochim Biophys Acta (1971) 1.28
POLTERGEIST functions to regulate meristem development downstream of the CLAVATA loci. Development (2000) 1.21
Properties of centre-hyperpolarizing, red-sensitive bipolar cells in the turtle retina. J Physiol (1975) 1.16
Potential affinity labels for the opiate receptor based on fentanyl and related compounds. J Med Chem (1982) 1.16
Mu-, delta- and kappa-opioid receptor populations are differentially altered in distinct areas of postmortem brains of Alzheimer's disease patients. Brain Res (2001) 1.15
Kinetics of opiate receptor inactivation by sulfhydryl reagents: evidence for conformational change in presence of sodium ions. Proc Natl Acad Sci U S A (1975) 1.11
Receptor affinity and pharmacological potency of a series of narcotic analgesic, anti-diarrheal and neuroleptic drugs. Eur J Pharmacol (1977) 1.10
The effects of the morphine analogue levorphanol on leukocytes. Metabolic effects at rest and during phagocytosis. J Clin Invest (1971) 1.10
From transforming growth factor-beta signaling to androgen action: identification of Smad3 as an androgen receptor coregulator in prostate cancer cells. Proc Natl Acad Sci U S A (2001) 1.09
Solubilization of a stereospecific opiate-macromolecular complex from rat brain. Science (1975) 1.08
Specific, high affinity [3H]ethylketocyclazocine binding in rat central nervous system: lack of evidence for kappa receptors. J Pharmacol Exp Ther (1980) 1.07
3H-ethylketocyclazocine binding: lack of evidence for a separate kappa receptor in rats CNS. Eur J Pharmacol (1979) 1.07
Effect of levorphanol on putrescine transport in Escherichia coli. Mol Pharmacol (1970) 1.04
Selective protection of stereospecific enkephalin and opiate binding against inactivation by N-ethylmaleimide: evidence for two classes of opiate receptors. Proc Natl Acad Sci U S A (1980) 1.04
Electrical responses of double cones in the turtle retina. J Physiol (1974) 1.03
Comparative studies on synaptosomes: uptake of (N-Me-3H)choline by synaptosomes from squid optic lobes. J Neurochem (1973) 0.99
Differential induction of androgen receptor transactivation by different androgen receptor coactivators in human prostate cancer DU145 cells. Endocrine (1999) 0.98
Purification of an active opioid-binding protein from bovine striatum. J Biol Chem (1985) 0.97
Solubilization of an active opiate receptor from Bufo marinus. Eur J Pharmacol (1980) 0.97
Structure-function aspects and inhibitor design of type 5 17beta-hydroxysteroid dehydrogenase (AKR1C3). Mol Cell Endocrinol (2001) 0.96
Covalent labeling of opioid receptors with radioiodinated human beta-endorphin. Identification of binding site subunit. J Biol Chem (1985) 0.96
Role of protein kinase C (PKC) in agonist-induced mu-opioid receptor down-regulation: II. Activation and involvement of the alpha, epsilon, and zeta isoforms of PKC. J Neurochem (1999) 0.95
mu and delta-opioid receptor agonists induce mitogen-activated protein kinase (MAPK) activation in the absence of receptor internalization. Neuropharmacology (2000) 0.95
Opiate receptors and their interactions with agnoists and antagonists. Life Sci (1975) 0.93
Human nonpancreatic secreted phospholipase A2: interfacial parameters, substrate specificities, and competitive inhibitors. Biochemistry (1993) 0.92
Solubilization and characterization of active opiate binding sites from mammalian brain. J Pharmacol Exp Ther (1982) 0.92
Decreased expression of smooth muscle alpha-actin results in decreased contractile function of the mouse bladder. J Urol (2004) 0.92
Tyrosine phosphorylation of the delta-opioid receptor. Evidence for its role in mitogen-activated protein kinase activation and receptor internalization*. Biochem Pharmacol (2000) 0.91
Differential induction of the androgen receptor transcriptional activity by selective androgen receptor coactivators. Keio J Med (1999) 0.91
Ontological development of opiate receptors in rodent brain. Brain Res (1976) 0.90
Solubilization and characterization of mu, delta, and kappa opioid binding sites from guinea pig brain: physical separation of kappa receptors. Proc Natl Acad Sci U S A (1984) 0.90
Sodium ions increase the binding of the antagonist peptide ICI 174864 to the delta-opiate receptor. Neuropeptides (1986) 0.90
Multiple opiate receptors: alcohol selectively inhibits binding to delta receptors. Science (1981) 0.89
Metabolism of polyamines in mouse neuroblastoma cells in culture: formation of GABA and putreanine. J Neurochem (1975) 0.89
Evidence for the presence of disulfide bridges in opioid receptors essential for ligand binding. Possible role in receptor activation. J Mol Recognit (1989) 0.87
The opiate receptors. Annu Rev Pharmacol Toxicol (1978) 0.87
Identification of a neurorestrictive suppressor element (NRSE) in the human mu-opioid receptor gene. Brain Res Mol Brain Res (2001) 0.87
Role of protein kinase C (PKC) in agonist-induced mu-opioid receptor down-regulation: I. PKC translocation to the membrane of SH-SY5Y neuroblastoma cells is induced by mu-opioid agonists. J Neurochem (1999) 0.86
Mutation of tyrosine 318 (Y318F) in the delta-opioid receptor attenuates tyrosine phosphorylation, agonist-dependent receptor internalization, and mitogen-activated protein kinase activation. Brain Res Mol Brain Res (2000) 0.86
Opiate receptors in cultures of fetal mouse dorsal root ganglia (DRG) and spinal cord: predominance in DRG neurites. Brain Res (1978) 0.85
Power spectral measurements of noise in the turtle tetina [proceedings]. J Physiol (1976) 0.85
The effect of the morphine analog levorphanol on phagocytosing leukocytes. A morphologic study. Lab Invest (1971) 0.85
Cross-linking of human [125I]beta-endorphin to opioid receptors in rat striatal membranes: biochemical evidence for the existence of a mu/delta opioid receptor complex. J Pharmacol Exp Ther (1990) 0.84
Initiation of chains by RNA polymerase and the effects of inhibitors studied by a direct filtration technique. Biochim Biophys Acta (1968) 0.84
Genetic manipulation to identify limiting steps and develop strategies for high-level expression of penicillin acylase in Escherichia coli. Biotechnol Bioeng (1999) 0.84
Mammalian 3 alpha-hydroxysteroid dehydrogenases. Steroids (1996) 0.84
Heparin protects BALB/c mice from mite-induced airway allergic inflammation. Int J Immunopathol Pharmacol (2013) 0.84
Localization of promoter elements in the human mu-opioid receptor gene and regulation by DNA methylation. Brain Res Mol Brain Res (1999) 0.83
Selective changes in mu, delta and kappa opioid receptor binding in certain limbic regions of the brain in Alzheimer's disease patients. Brain Res (1987) 0.83
Characterization and partial purification of solubilized active opiate receptors from toad brain. Proc Natl Acad Sci U S A (1981) 0.83
Effect of SecB chaperone on production of periplasmic penicillin acylase in Escherichia coli. Biotechnol Prog (1999) 0.82
Antithrombotic effect of crotalin, a platelet membrane glycoprotein Ib antagonist from venom of Crotalus atrox. Blood (1998) 0.82
Lectin binding of solubilized opiate receptors: evidence for their glycoprotein nature. Biochem Biophys Res Commun (1982) 0.82
A re-evaluation of the molecular size of duck epsilon-crystallin and its comparison with avian lactate dehydrogenases. Biochim Biophys Acta (1988) 0.81
The bovine mu-opioid receptor: cloning of cDNA and pharmacological characterization of the receptor expressed in mammalian cells. Brain Res Mol Brain Res (1999) 0.81
Identification of distinct binding site subunits of mu and delta opioid receptors. Biochemistry (1986) 0.81
The nature of opiate receptors in toad brain. Life Sci (1983) 0.81
Physicochemical characterization of beta-crystallins from bovine lenses: hydrodynamic and aggregation properties. J Protein Chem (1989) 0.81
Sulfhydryl groups on opioid receptors revisited. Evidence for two sulfhydryl groups at or near the active site of the mu opioid receptor. Receptor (1992) 0.80
Reversible inhibition of RNA phage replication and macromolecular synthesis by levorphanol. Biochem Biophys Res Commun (1970) 0.80
Characterization of solubilized opioid receptors: reconstitution and uncoupling of guanine nucleotide-sensitive agonist binding. J Neurochem (1992) 0.80
Opiate binding sites in the retina: properties and distribution. J Pharmacol Exp Ther (1980) 0.80
Brain stimulation-induced feeding alters regional opioid receptor binding in the rat: an in vivo autoradiographic study. Brain Res (1990) 0.80
Diphenhydramine potentiates narcotic but not endogenous opioid analgesia. Neuropeptides (1985) 0.80
Antagonist-induced opiate receptor upregulation in cultures of fetal mouse spinal cord-ganglion explants. Brain Res (1986) 0.80
Effects of parabrachial opioid antagonism on stimulation-induced feeding. Brain Res (1991) 0.80
Selective depression by opioid peptides of sensory-evoked dorsal-horn network responses in organized spinal cord cultures. Brain Res (1978) 0.80
The selective inhibition of ribosomal RNA synthesis in E. coli by 2,4-Dinitrophenol. Mol Pharmacol (1966) 0.80
A member of the heat shock protein 40 family, hlj1, binds to the carboxyl tail of the human mu opioid receptor. Brain Res (2006) 0.80
In search of the opiate receptor. Am J Med Sci (1973) 0.80
Recent studies on opioid receptors: heterogeneity and purification. Ann N Y Acad Sci (1986) 0.80
"Mammalian 3 alpha-hydroxysteroid dehydrogenases". Steroids (1997) 0.79
Reconstitution of a purified mu-opioid binding protein in liposomes: selective, high affinity, GTP gamma S-sensitive mu-opioid agonist binding is restored. Biochem Biophys Res Commun (1993) 0.79
Manipulation of carbon assimilation with respect to expression of the pac gene for improving production of penicillin acylase in Escherichia coli. J Biotechnol (1999) 0.79
Effects of stress on opioid receptor binding in the rat central nervous system. Neuroscience (1992) 0.79
Affinity chromatography of solubilized opioid binding sites using CH-Sepharose modified with a new naltrexone derivative. Biochem Biophys Res Commun (1984) 0.79