Published in CNS Drugs on April 01, 2010
Automated design of ligands to polypharmacological profiles. Nature (2012) 3.54
The vagus nerve and the inflammatory reflex--linking immunity and metabolism. Nat Rev Endocrinol (2012) 1.59
Cholinergic contributions to the cognitive symptoms of schizophrenia and the viability of cholinergic treatments. Neuropharmacology (2010) 0.97
Mouse pharmacological models of cognitive disruption relevant to schizophrenia. Neuropharmacology (2011) 0.95
Adjunctive use of nonsteroidal anti-inflammatory drugs for schizophrenia: a meta-analytic investigation of randomized controlled trials. Schizophr Bull (2013) 0.91
Nicotine differentially modulates antisaccade performance in healthy male non-smoking volunteers stratified for low and high accuracy. Psychopharmacology (Berl) (2011) 0.85
Acetylcholinesterase Inhibitors (AChEI's) for the treatment of visual hallucinations in schizophrenia: a review of the literature. BMC Psychiatry (2010) 0.84
Translational Aspects of the Novel Object Recognition Task in Rats Abstinent Following Sub-Chronic Treatment with Phencyclidine (PCP): Effects of Modafinil and Relevance to Cognitive Deficits in Schizophrenia. Front Psychiatry (2010) 0.79
Translating advances in the molecular basis of schizophrenia into novel cognitive treatment strategies. Br J Pharmacol (2017) 0.79
Critics on "adjunctive memantine therapy for cognitive impairment in chronic schizophrenia: a placebo-controlled pilot study". Psychiatry Investig (2013) 0.78
Assessing the synergy between cholinomimetics and memantine as augmentation therapy in cognitive impairment in schizophrenia. A virtual human patient trial using quantitative systems pharmacology. Front Pharmacol (2015) 0.78
Adjunctive treatment for cognitive impairment in patients with chronic schizophrenia: a double-blind, placebo-controlled study. Neuropsychiatr Dis Treat (2014) 0.76
Effectiveness of rivastigmine on positive, negative, and cognitive symptoms of schizophrenia: a double-blind clinical trial. Ther Adv Psychopharmacol (2016) 0.75
Treating Negative Symptoms in Schizophrenia: an Update. Curr Treat Options Psychiatry (2016) 0.75
Effect of Pharmacological Interventions on the Fronto-Cingulo-Parietal Cognitive Control Network in Psychiatric Disorders: A Transdiagnostic Systematic Review of fMRI Studies. Front Psychiatry (2016) 0.75
Task- and Treatment Length-Dependent Effects of Vortioxetine on Scopolamine-Induced Cognitive Dysfunction and Hippocampal Extracellular Acetylcholine in Rats. J Pharmacol Exp Ther (2016) 0.75
Hormone replacement therapy and incidence of Alzheimer disease in older women: the Cache County Study. JAMA (2002) 6.72
Prevalence of cognitive impairment without dementia in the United States. Ann Intern Med (2008) 5.34
The Aging, Demographics, and Memory Study: study design and methods. Neuroepidemiology (2005) 4.44
Treatment course with antidepressant therapy in late-life depression. Am J Psychiatry (2012) 2.94
Comparison of clinical and neuropathologic diagnoses of Alzheimer's disease in 3 epidemiologic samples. Alzheimers Dement (2006) 2.51
Point and 5-year period prevalence of neuropsychiatric symptoms in dementia: the Cache County Study. Int J Geriatr Psychiatry (2008) 2.32
Reducing suicidal ideation in depressed older primary care patients. J Am Geriatr Soc (2006) 2.11
Head injury in early adulthood and the lifetime risk of depression. Arch Gen Psychiatry (2002) 1.97
Psychiatric disease in the twenty-first century: The case for subcortical ischemic depression. Biol Psychiatry (2006) 1.94
Cognitive function in late life depression: relationships to depression severity, cerebrovascular risk factors and processing speed. Biol Psychiatry (2006) 1.92
Depression treatment preferences in older primary care patients. Gerontologist (2006) 1.92
Prevalence of dementia in Latin America: a collaborative study of population-based cohorts. Int Psychogeriatr (2009) 1.76
Provisional diagnostic criteria for depression of Alzheimer disease. Am J Geriatr Psychiatry (2002) 1.75
Greater risk of dementia when spouse has dementia? The Cache County study. J Am Geriatr Soc (2010) 1.73
Dorsolateral prefrontal cortex and anterior cingulate cortex white matter alterations in late-life depression. Biol Psychiatry (2006) 1.73
Support for the vascular depression hypothesis in late-life depression: results of a 2-site, prospective, antidepressant treatment trial. Arch Gen Psychiatry (2010) 1.72
Incidence of dementia and cognitive impairment, not dementia in the United States. Ann Neurol (2011) 1.63
Prevalence of neuropsychiatric symptoms and their association with functional limitations in older adults in the United States: the aging, demographics, and memory study. J Am Geriatr Soc (2010) 1.60
Late-life depression and microstructural abnormalities in dorsolateral prefrontal cortex white matter. Am J Psychiatry (2004) 1.55
Prefrontal neuropsychological predictors of treatment remission in late-life depression. Neuropsychopharmacology (2004) 1.48
Symptomatic remission in patients with bipolar mania: results from a double-blind, placebo-controlled trial of risperidone monotherapy. J Clin Psychiatry (2005) 1.47
Vascular risk factors and cognitive decline among elderly male twins. Neurology (2006) 1.47
Clinical characteristics of magnetic resonance imaging-defined subcortical ischemic depression. Biol Psychiatry (2004) 1.46
White matter hyperintensity progression and late-life depression outcomes. Arch Gen Psychiatry (2003) 1.46
The persistence of neuropsychiatric symptoms in dementia: the Cache County Study. Int J Geriatr Psychiatry (2004) 1.46
Persistent mild cognitive impairment in geriatric depression. Int Psychogeriatr (2006) 1.45
Testing for cytochrome P450 polymorphisms in adults with non-psychotic depression treated with selective serotonin reuptake inhibitors (SSRIs). Evid Rep Technol Assess (Full Rep) (2007) 1.42
Depressive state- and disease-related alterations in neural responses to affective and executive challenges in geriatric depression. Am J Psychiatry (2008) 1.42
Characteristics of patients assisted at an ambulatory of dementia from a university hospital. Arq Neuropsiquiatr (2008) 1.39
Influence of serotonin transporter promoter region polymorphisms on hippocampal volumes in late-life depression. Arch Gen Psychiatry (2005) 1.39
Greater MRI lesion volumes in elderly depressed subjects than in control subjects. Psychiatry Res (2005) 1.39
Cognitive intervention in amnestic Mild Cognitive Impairment: a systematic review. Neurosci Biobehav Rev (2012) 1.36
Serial MR imaging of volumes of hyperintense white matter lesions in elderly patients: correlation with vascular risk factors. AJR Am J Roentgenol (2003) 1.34
Midlife activity predicts risk of dementia in older male twin pairs. Alzheimers Dement (2008) 1.32
Hippocampal volume and antidepressant response in geriatric depression. Int J Geriatr Psychiatry (2002) 1.31
Aging, gender, and the elderly adult brain: an examination of analytical strategies. Neurobiol Aging (2006) 1.30
Population-based study of medical comorbidity in early dementia and "cognitive impairment, no dementia (CIND)": association with functional and cognitive impairment: The Cache County Study. Am J Geriatr Psychiatry (2005) 1.23
Profiles of depressive symptoms in older adults diagnosed with major depression: latent cluster analysis. Am J Geriatr Psychiatry (2009) 1.21
Duke Twins Study of Memory in Aging in the NAS-NRC Twin Registry. Twin Res Hum Genet (2006) 1.19
A preliminary metabolomic analysis of older adults with and without depression. Int J Geriatr Psychiatry (2007) 1.19
The vascular depression subtype: evidence of internal validity. Biol Psychiatry (2008) 1.19
Amyloid-associated depression: a prodromal depression of Alzheimer disease? Arch Gen Psychiatry (2008) 1.18
The incidence of mental and behavioral disturbances in dementia: the cache county study. J Neuropsychiatry Clin Neurosci (2003) 1.18
Review of evidence for genetic testing for CYP450 polymorphisms in management of patients with nonpsychotic depression with selective serotonin reuptake inhibitors. Genet Med (2007) 1.17
Calcium and vitamin D intakes may be positively associated with brain lesions in depressed and nondepressed elders. Nutr Res (2008) 1.16
Neuropsychiatric symptoms and the risk of institutionalization and death: the aging, demographics, and memory study. J Am Geriatr Soc (2011) 1.15
Neurocognitive correlates of response to treatment in late-life depression. Am J Geriatr Psychiatry (2008) 1.15
The neurosteroid allopregnanolone is reduced in prefrontal cortex in Alzheimer's disease. Biol Psychiatry (2006) 1.15
National Institutes of Health Pathways to Prevention Workshop: the role of opioids in the treatment of chronic pain. Ann Intern Med (2015) 1.12
Localization of age-associated white matter hyperintensities in late-life depression. Prog Neuropsychopharmacol Biol Psychiatry (2003) 1.11
Three-year incidence of first-onset depressive syndrome in a population sample of older adults: the Cache County study. Am J Geriatr Psychiatry (2006) 1.10
Psychosocial and clinical predictors of unipolar depression outcome in older adults. Int J Geriatr Psychiatry (2002) 1.10
Contribution of depression to cognitive impairment and dementia in older adults. Neurologist (2007) 1.09
Cognitive performance and informant reports in the diagnosis of cognitive impairment and dementia in African Americans and whites. Alzheimers Dement (2009) 1.08
Orbitofrontal cortex volume in late life depression: influence of hyperintense lesions and genetic polymorphisms. Psychol Med (2007) 1.07
Social support and locus of control as predictors of adherence to antidepressant medication in an elderly population. Am J Geriatr Psychiatry (2005) 1.06
Gender differences in the association between religious involvement and depression: the Cache County (Utah) study. J Gerontol B Psychol Sci Soc Sci (2006) 1.06
The impact of religious practice and religious coping on geriatric depression. Int J Geriatr Psychiatry (2003) 1.05
Smaller orbital frontal cortex volumes associated with functional disability in depressed elders. Biol Psychiatry (2003) 1.05
Reduction of dorsolateral prefrontal cortex gray matter in late-life depression. Psychiatry Res (2011) 1.05
The brain-derived neurotrophic factor VAL66MET polymorphism and cerebral white matter hyperintensities in late-life depression. Am J Geriatr Psychiatry (2008) 1.04
Subcortical lesion severity and orbitofrontal cortex volume in geriatric depression. Biol Psychiatry (2003) 1.03
Allelic differences in the brain-derived neurotrophic factor Val66Met polymorphism in late-life depression. Am J Geriatr Psychiatry (2007) 1.02
Widespread effects of hyperintense lesions on cerebral white matter structure. AJR Am J Roentgenol (2007) 1.02
Hippocampus shape analysis and late-life depression. PLoS One (2008) 1.02
Anatomic location and laterality of MRI signal hyperintensities in late-life depression. J Psychosom Res (2002) 1.01
Early parental death and remarriage of widowed parents as risk factors for Alzheimer disease: the Cache County study. Am J Geriatr Psychiatry (2011) 1.00
MRI-defined vascular depression: a review of the construct. Int J Geriatr Psychiatry (2010) 0.98
The brain-derived neurotrophic factor Val66Met polymorphism, hippocampal volume, and cognitive function in geriatric depression. Am J Geriatr Psychiatry (2010) 0.98
Cognitive rehabilitation combined with drug treatment in Alzheimer's disease patients: a pilot study. Clin Rehabil (2005) 0.97
Implementing a disease management intervention for depression in primary care: a random work sampling study. Gen Hosp Psychiatry (2003) 0.97
APOE related hippocampal shape alteration in geriatric depression. Neuroimage (2008) 0.96
Amygdala volume in late-life depression: relationship with age of onset. Am J Geriatr Psychiatry (2011) 0.96
Quality of life and physical activity associated to lower prevalence of depression in community-dwelling elderly subjects from Sao Paulo. J Affect Disord (2013) 0.96
Change in stress and social support as predictors of cognitive decline in older adults with and without depression. Int J Geriatr Psychiatry (2011) 0.96
Time-to-remission from geriatric depression: psychosocial and clinical factors. Am J Geriatr Psychiatry (2002) 0.95
The effects of antidepressant medication adherence as well as psychosocial and clinical factors on depression outcome among older adults. Int J Geriatr Psychiatry (2008) 0.95
Differences in brain volumes among males and female hormone-therapy users and nonusers. Psychiatry Res (2006) 0.95
White matter and subcortical gray matter lesion volume changes and late-life depression outcome: a 4-year magnetic resonance imaging study. Int Psychogeriatr (2006) 0.95
Fiber tract-specific white matter lesion severity Findings in late-life depression and by AGTR1 A1166C genotype. Hum Brain Mapp (2011) 0.94
A three-factor analytic model of the MADRS in geriatric depression. Int J Geriatr Psychiatry (2003) 0.93
Age-dependent reduction of amygdala volume in bipolar disorder. Psychiatry Res (2008) 0.93
Differential patterns of cognitive decline in anterior and posterior white matter hyperintensity progression. Stroke (2010) 0.92
Religion and the presence and severity of depression in older adults. Am J Geriatr Psychiatry (2012) 0.92
Association analysis of the COMT/MTHFR genes and geriatric depression: an MRI study of the putamen. Int J Geriatr Psychiatry (2009) 0.92
[Fulminant non-Hodgkin lymphoma presenting as lactic acidosis and acute liver failure: case report and literature review]. Acta Gastroenterol Latinoam (2009) 0.92
Clinically significant depressive symptoms and associated factors in community elderly subjects from Sao Paulo, Brazil. Am J Geriatr Psychiatry (2009) 0.91
[Combined instruments on the evaluation of dementia in the elderly: preliminary results]. Arq Neuropsiquiatr (2003) 0.91
Association of five-factor model personality domains and facets with presence, onset, and treatment outcomes of major depression in older adults. Am J Geriatr Psychiatry (2013) 0.91
Fatigue as a core symptom in major depressive disorder: overview and the role of bupropion. Expert Rev Neurother (2007) 0.90
Fruit, vegetable, and antioxidant intakes are lower in older adults with depression. J Acad Nutr Diet (2012) 0.90
White matter lesion volumes and caudate volumes in late-life depression. Int J Geriatr Psychiatry (2006) 0.90
Functional evidence implicating a novel TOR1A mutation in idiopathic, late-onset focal dystonia. J Med Genet (2009) 0.90
Clinical correlates of anxious depression among elderly patients with depression. J Affect Disord (2005) 0.90
Depression, hippocampal volume changes, and cognitive decline in a clinical sample of older depressed outpatients and non-depressed controls. Aging Ment Health (2012) 0.90
Heterogeneity in symptom profiles among older adults diagnosed with major depression. Int Psychogeriatr (2011) 0.90
Associations among the NEO Personality Inventory, Revised and the serotonin transporter gene-linked polymorphic region in elders: effects of depression and gender. Psychiatr Genet (2003) 0.89
Cross-cultural considerations in administering the center for epidemiologic studies depression scale. Gerontology (2010) 0.89
Vascular nutritional correlates of late-life depression. Am J Geriatr Psychiatry (2006) 0.89