Published in Genet Med on December 01, 2007
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The promise and reality of pharmacogenetics in psychiatry. Psychiatr Clin North Am (2010) 0.92
Evidence based medicine meets genomic medicine. Genet Med (2007) 0.85
Role of cytochrome P450 genotype in the steps toward personalized drug therapy. Pharmgenomics Pers Med (2011) 0.83
Finding the missing heritability of complex diseases. Nature (2009) 67.95
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Large recurrent microdeletions associated with schizophrenia. Nature (2008) 20.25
A whole-genome association study of major determinants for host control of HIV-1. Science (2007) 15.19
Rare variants create synthetic genome-wide associations. PLoS Biol (2010) 14.43
Genetic variation in IL28B and spontaneous clearance of hepatitis C virus. Nature (2009) 13.99
Common variants conferring risk of schizophrenia. Nature (2009) 10.37
Uncovering the roles of rare variants in common disease through whole-genome sequencing. Nat Rev Genet (2010) 9.53
Discerning the ancestry of European Americans in genetic association studies. PLoS Genet (2007) 7.81
Clopidogrel use and long-term clinical outcomes after drug-eluting stent implantation. JAMA (2006) 7.81
De novo mutations in epileptic encephalopathies. Nature (2013) 7.42
WGAViewer: software for genomic annotation of whole genome association studies. Genome Res (2008) 7.15
A genome-wide association study in chronic obstructive pulmonary disease (COPD): identification of two major susceptibility loci. PLoS Genet (2009) 6.93
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Interleukin-28B polymorphism improves viral kinetics and is the strongest pretreatment predictor of sustained virologic response in genotype 1 hepatitis C virus. Gastroenterology (2010) 6.14
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Frontotemporal dementia: clinicopathological correlations. Ann Neurol (2006) 5.14
Tissue-specific genetic control of splicing: implications for the study of complex traits. PLoS Biol (2008) 5.08
A genome-wide investigation of SNPs and CNVs in schizophrenia. PLoS Genet (2009) 5.01
Society for Ambulatory Anesthesia guidelines for the management of postoperative nausea and vomiting. Anesth Analg (2007) 4.95
ITPA gene variants protect against anaemia in patients treated for chronic hepatitis C. Nature (2010) 4.64
Selection and evaluation of tagging SNPs in the neuronal-sodium-channel gene SCN1A: implications for linkage-disequilibrium gene mapping. Am J Hum Genet (2003) 4.58
The Aging, Demographics, and Memory Study: study design and methods. Neuroepidemiology (2005) 4.44
Does this patient with headache have a migraine or need neuroimaging? JAMA (2006) 4.35
Whole-genome sequencing of a single proband together with linkage analysis identifies a Mendelian disease gene. PLoS Genet (2010) 4.29
HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin. Nat Genet (2009) 4.11
HLA-A*3101 and carbamazepine-induced hypersensitivity reactions in Europeans. N Engl J Med (2011) 3.93
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Common genetic variation and the control of HIV-1 in humans. PLoS Genet (2009) 3.68
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IL28B genotype is associated with differential expression of intrahepatic interferon-stimulated genes in patients with chronic hepatitis C. Hepatology (2010) 3.57
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Association of multidrug resistance in epilepsy with a polymorphism in the drug-transporter gene ABCB1. N Engl J Med (2003) 3.37
Clinical application of exome sequencing in undiagnosed genetic conditions. J Med Genet (2012) 3.33
Noninvasive staging of non-small cell lung cancer: a review of the current evidence. Chest (2003) 3.16
Cerebrospinal fluid profile in frontotemporal dementia and Alzheimer's disease. Ann Neurol (2005) 3.09
Long-range LD can confound genome scans in admixed populations. Am J Hum Genet (2008) 3.06
Hepatitis C pharmacogenetics: state of the art in 2010. Hepatology (2011) 2.99
Treatment course with antidepressant therapy in late-life depression. Am J Psychiatry (2012) 2.94
Host determinants of HIV-1 control in African Americans. J Infect Dis (2010) 2.90
Multicentre search for genetic susceptibility loci in sporadic epilepsy syndrome and seizure types: a case-control study. Lancet Neurol (2007) 2.88
An IL28B polymorphism determines treatment response of hepatitis C virus genotype 2 or 3 patients who do not achieve a rapid virologic response. Gastroenterology (2010) 2.87
Charlson Index comorbidity adjustment for ischemic stroke outcome studies. Stroke (2004) 2.86
A polymorphism near IL28B is associated with spontaneous clearance of acute hepatitis C virus and jaundice. Gastroenterology (2010) 2.78
Prognosis of pulmonary arterial hypertension: ACCP evidence-based clinical practice guidelines. Chest (2004) 2.74
Evidence for the treatment of patients with pulmonary nodules: when is it lung cancer?: ACCP evidence-based clinical practice guidelines (2nd edition). Chest (2007) 2.72
Systematic review: comparative effectiveness of angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers for treating essential hypertension. Ann Intern Med (2007) 2.69
Creating a global rare disease patient registry linked to a rare diseases biorepository database: Rare Disease-HUB (RD-HUB). Contemp Clin Trials (2010) 2.69
Priorities and standards in pharmacogenetic research. Nat Genet (2005) 2.65
Rare deletions at 16p13.11 predispose to a diverse spectrum of sporadic epilepsy syndromes. Am J Hum Genet (2010) 2.61
Positive selection on a human-specific transcription factor binding site regulating IL4 expression. Curr Biol (2003) 2.59
Next generation disparities in human genomics: concerns and remedies. Trends Genet (2009) 2.53
Comparison of clinical and neuropathologic diagnoses of Alzheimer's disease in 3 epidemiologic samples. Alzheimers Dement (2006) 2.51
Which evolutionary processes influence natural genetic variation for phenotypic traits? Nat Rev Genet (2007) 2.45
A single-nucleotide polymorphism tagging set for human drug metabolism and transport. Nat Genet (2004) 2.44
Performance characteristics of different modalities for diagnosis of suspected lung cancer: summary of published evidence. Chest (2003) 2.42
Genetic predictors of the maximum doses patients receive during clinical use of the anti-epileptic drugs carbamazepine and phenytoin. Proc Natl Acad Sci U S A (2005) 2.39
Geographical genomics of human leukocyte gene expression variation in southern Morocco. Nat Genet (2009) 2.38
Hypertension improvement project: randomized trial of quality improvement for physicians and lifestyle modification for patients. Hypertension (2009) 2.37
Ancient and recent positive selection transformed opioid cis-regulation in humans. PLoS Biol (2005) 2.37
De novo mutations in ATP1A3 cause alternating hemiplegia of childhood. Nat Genet (2012) 2.34
Genomics meets HIV-1. Nat Rev Microbiol (2006) 2.34
Symptomatic oxygen for non-hypoxaemic chronic obstructive pulmonary disease. Cochrane Database Syst Rev (2011) 2.32
Point and 5-year period prevalence of neuropsychiatric symptoms in dementia: the Cache County Study. Int J Geriatr Psychiatry (2008) 2.32
Pharmacogenetics in the laboratory and the clinic. N Engl J Med (2003) 2.12
SVA: software for annotating and visualizing sequenced human genomes. Bioinformatics (2011) 2.11
Reducing suicidal ideation in depressed older primary care patients. J Am Geriatr Soc (2006) 2.11
Geographic variation in carotid revascularization among Medicare beneficiaries, 2003-2006. Arch Intern Med (2010) 2.08
Mutations in the profilin 1 gene cause familial amyotrophic lateral sclerosis. Nature (2012) 2.08
Cold urticaria, immunodeficiency, and autoimmunity related to PLCG2 deletions. N Engl J Med (2012) 2.08
Interpretation of association signals and identification of causal variants from genome-wide association studies. Am J Hum Genet (2010) 2.06
Dissemination of Evidence-based Practice Center reports. Ann Intern Med (2005) 2.05
Nova2 interacts with a cis-acting polymorphism to influence the proportions of drug-responsive splice variants of SCN1A. Am J Hum Genet (2007) 2.04
Interpretive Diagnostic Error Reduction in Surgical Pathology and Cytology: Guideline From the College of American Pathologists Pathology and Laboratory Quality Center and the Association of Directors of Anatomic and Surgical Pathology. Arch Pathol Lab Med (2015) 2.01
Susceptibility to amoxicillin-clavulanate-induced liver injury is influenced by multiple HLA class I and II alleles. Gastroenterology (2011) 2.01
Screening the human exome: a comparison of whole genome and whole transcriptome sequencing. Genome Biol (2010) 2.00
Medical therapy for pulmonary arterial hypertension: ACCP evidence-based clinical practice guidelines. Chest (2004) 2.00
Head injury in early adulthood and the lifetime risk of depression. Arch Gen Psychiatry (2002) 1.97
Psychiatric disease in the twenty-first century: The case for subcortical ischemic depression. Biol Psychiatry (2006) 1.94
Cognitive function in late life depression: relationships to depression severity, cerebrovascular risk factors and processing speed. Biol Psychiatry (2006) 1.92
Depression treatment preferences in older primary care patients. Gerontologist (2006) 1.92
Genome-wide mRNA expression correlates of viral control in CD4+ T-cells from HIV-1-infected individuals. PLoS Pathog (2010) 1.90
Founding mothers of Jewish communities: geographically separated Jewish groups were independently founded by very few female ancestors. Am J Hum Genet (2002) 1.89