Published in Environ Health Perspect on March 18, 2010
Evaluation of the association between arsenic and diabetes: a National Toxicology Program workshop review. Environ Health Perspect (2012) 2.05
Inhibiting TGF-β activity improves respiratory function in mdx mice. Am J Pathol (2011) 1.09
Role of pericytes in skeletal muscle regeneration and fat accumulation. Stem Cells Dev (2013) 1.01
Sodium arsenite delays the differentiation of C2C12 mouse myoblast cells and alters methylation patterns on the transcription factor myogenin. Toxicol Appl Pharmacol (2010) 0.94
Sodium arsenite represses the expression of myogenin in C2C12 mouse myoblast cells through histone modifications and altered expression of Ezh2, Glp, and Igf-1. Toxicol Appl Pharmacol (2012) 0.88
Antidiabetic effects of pterosin A, a small-molecular-weight natural product, on diabetic mouse models. Diabetes (2012) 0.87
Effects of arsenic on osteoblast differentiation in vitro and on bone mineral density and microstructure in rats. Environ Health Perspect (2014) 0.87
Arsenic induces sustained impairment of skeletal muscle and muscle progenitor cell ultrastructure and bioenergetics. Free Radic Biol Med (2014) 0.85
Arsenic exposure inhibits myogenesis and neurogenesis in P19 stem cells through repression of the β-catenin signaling pathway. Toxicol Sci (2012) 0.84
Environmental endocrine disruption of energy metabolism and cardiovascular risk. Curr Diab Rep (2014) 0.80
Low-Concentration Arsenic Trioxide Inhibits Skeletal Myoblast Cell Proliferation via a Reactive Oxygen Species-Independent Pathway. PLoS One (2015) 0.79
Arsenic exposure to killifish during embryogenesis alters muscle development. Toxicol Sci (2011) 0.79
Embryonic-only arsenic exposure in killifish (Fundulus heteroclitus) reduces growth and alters muscle IGF levels one year later. Aquat Toxicol (2017) 0.75
Zebrafish: A Model for the Study of Toxicants Affecting Muscle Development and Function. Int J Mol Sci (2016) 0.75
Arsenic inhibits stem cell differentiation by altering the interplay between the Wnt3a and Notch signaling pathways. Toxicol Rep (2016) 0.75
Arsenic Promotes NF-Κb-Mediated Fibroblast Dysfunction and Matrix Remodeling to Impair Muscle Stem Cell Function. Stem Cells (2016) 0.75
Arsenic trioxide alters the differentiation of mouse embryonic stem cell into cardiomyocytes. Sci Rep (2015) 0.75
Photobiomodulation Protects and Promotes Differentiation of C2C12 Myoblast Cells Exposed to Snake Venom. PLoS One (2016) 0.75
Assessment of arsenic trioxide toxicity on cock muscular tissue: alterations of oxidative damage parameters, inflammatory cytokines and heat shock proteins. Ecotoxicology (2017) 0.75
Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo. Nat Cell Biol (2001) 10.85
The myoD gene family: nodal point during specification of the muscle cell lineage. Science (1991) 9.53
Correlation of terminal cell cycle arrest of skeletal muscle with induction of p21 by MyoD. Science (1995) 7.25
The MyoD family and myogenesis: redundancy, networks, and thresholds. Cell (1993) 6.24
Dwarfism, impaired skin development, skeletal muscle atrophy, delayed bone development, and impeded adipogenesis in mice lacking Akt1 and Akt2. Genes Dev (2003) 5.91
Identification of a novel population of muscle stem cells in mice: potential for muscle regeneration. J Cell Biol (2002) 4.61
Use of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia (APL): I. As2O3 exerts dose-dependent dual effects on APL cells. Blood (1997) 3.56
Arsenic groundwater contamination in Middle Ganga Plain, Bihar, India: a future danger? Environ Health Perspect (2003) 2.89
Cellular signaling: pivoting around PDK-1. Cell (2000) 2.86
Physiological roles of PKB/Akt isoforms in development and disease. Biochem Soc Trans (2007) 2.70
Diabetes mellitus associated with arsenic exposure in Bangladesh. Am J Epidemiol (1998) 2.63
Arsenic exposure and type 2 diabetes: a systematic review of the experimental and epidemiological evidence. Environ Health Perspect (2006) 2.44
Mechanisms of disease: glucocorticoids, their placental metabolism and fetal 'programming' of adult pathophysiology. Nat Clin Pract Endocrinol Metab (2007) 2.44
Regulatory mechanisms that coordinate skeletal muscle differentiation and cell cycle withdrawal. Curr Opin Cell Biol (1994) 2.44
Regulation of muscle differentiation by the MEF2 family of MADS box transcription factors. Dev Biol (1995) 2.28
Ingested inorganic arsenic and prevalence of diabetes mellitus. Am J Epidemiol (1994) 2.17
Myogenic signaling of phosphatidylinositol 3-kinase requires the serine-threonine kinase Akt/protein kinase B. Proc Natl Acad Sci U S A (1999) 1.81
Molecular mechanisms of the diabetogenic effects of arsenic: inhibition of insulin signaling by arsenite and methylarsonous acid. Environ Health Perspect (2007) 1.77
Phosphatidylinositol 3-kinase inhibitors block differentiation of skeletal muscle cells. J Biol Chem (1996) 1.56
Arsenic and diabetes and hypertension in human populations: a review. Toxicol Appl Pharmacol (2007) 1.31
Antifibrotic effects of suramin in injured skeletal muscle after laceration. J Appl Physiol (1985) (2003) 1.28
Phosphoinositide 3-kinase induces the transcriptional activity of MEF2 proteins during muscle differentiation. J Biol Chem (2000) 1.26
Insulin-like growth factors require phosphatidylinositol 3-kinase to signal myogenesis: dominant negative p85 expression blocks differentiation of L6E9 muscle cells. Mol Endocrinol (1998) 1.25
Induction of p18INK4c and its predominant association with CDK4 and CDK6 during myogenic differentiation. Mol Biol Cell (1996) 1.25
Arsenic-induced alteration in the expression of genes related to type 2 diabetes mellitus. Toxicol Appl Pharmacol (2007) 1.22
The involvement of PI 3-K/Akt-dependent up-regulation of Mcl-1 in the prevention of apoptosis of Hep3B cells by interleukin-6. Oncogene (2001) 1.22
Reduced placental 11beta-hydroxysteroid dehydrogenase type 2 mRNA levels in human pregnancies complicated by intrauterine growth restriction: an analysis of possible mechanisms. J Clin Endocrinol Metab (2001) 1.21
Consequences of birth weight for postnatal growth performance and carcass quality in pigs as related to myogenesis. J Anim Sci (2006) 1.21
Akt2, a novel functional link between p38 mitogen-activated protein kinase and phosphatidylinositol 3-kinase pathways in myogenesis. Mol Cell Biol (2004) 1.18
Altered skeletal muscle fiber composition and size precede whole-body insulin resistance in young men with low birth weight. J Clin Endocrinol Metab (2007) 1.16
Akt1 and Akt2 differently regulate muscle creatine kinase and myogenin gene transcription in insulin-induced differentiation of C2C12 myoblasts. Endocrinology (2002) 1.09
Altered PI3-kinase/Akt signalling in skeletal muscle of young men with low birth weight. PLoS One (2008) 1.08
Activation of myogenic precursor cells after muscle injury. Med Sci Sports Exerc (1992) 1.08
The effect of maternal undernutrition before muscle differentiation on the muscle fiber development of the newborn lamb. J Anim Sci (2005) 1.07
Cadmium exposure during pregnancy reduces birth weight and increases maternal and foetal glucocorticoids. Toxicol Lett (2009) 1.03
MyoD cannot compensate for the absence of myogenin during skeletal muscle differentiation in murine embryonic stem cells. Dev Biol (2001) 1.01
Development of approaches to improve the healing following muscle contusion. Cell Transplant (1999) 0.98
Maternal nutrition alters the expression of insulin-like growth factors in fetal sheep liver and skeletal muscle. J Endocrinol (2000) 0.98
Arsenate suppression of human keratinocyte programming. Mutat Res (1997) 0.97
Target gene selectivity of the myogenic basic helix-loop-helix transcription factor myogenin in embryonic muscle. Dev Biol (2007) 0.97
Sodium arsenite inhibits terminal differentiation of murine C3H 10T1/2 preadipocytes. Toxicol Appl Pharmacol (2000) 0.97
Low-level arsenite activates the transcription of genes involved in adipose differentiation. Cell Biol Toxicol (2004) 0.95
Phosphatidylinositol 3-kinase: a key regulator in adherens junction formation and function. Front Biosci (Landmark Ed) (2009) 0.94
Two myogenin-related genes are differentially expressed in Xenopus laevis myogenesis and differ in their ability to transactivate muscle structural genes. J Biol Chem (2001) 0.91
Prenatal and developmental toxicology of arsenicals. Adv Exp Med Biol (1984) 0.87
The role of Akt on arsenic trioxide suppression of 3T3-L1 preadipocyte differentiation. Cell Res (2005) 0.84
p53 response to arsenic exposure in epithelial cells: protein kinase B/Akt involvement. Toxicol Sci (2007) 0.84
Effects of perinatal high dose dexamethasone on skeletal muscle development in rats. Can J Vet Res (1989) 0.83
Characterization of cytotoxicity induced by arsenic trioxide (a potent anti-APL drug) in rat cardiac myocytes. J Trace Elem Med Biol (2008) 0.83
Arsenate perturbation of human keratinocyte differentiation. Cell Growth Differ (1994) 0.83
Experimental glycerol myopathy: a histological study. Acta Neuropathol (1990) 0.80
4E-BP functions as a metabolic brake used under stress conditions but not during normal growth. Genes Dev (2005) 2.28
Acetylation of yeast AMPK controls intrinsic aging independently of caloric restriction. Cell (2011) 2.10
The growth regulators warts/lats and melted interact in a bistable loop to specify opposite fates in Drosophila R8 photoreceptors. Cell (2005) 2.00
Prognostic factors of treatment outcomes in patients with granulocytic sarcoma. Acta Haematol (2009) 1.90
Krüppel-like factor 4, a tumor suppressor in hepatocellular carcinoma cells reverts epithelial mesenchymal transition by suppressing slug expression. PLoS One (2012) 1.87
Quantitative evaluation of focused ultrasound with a contrast agent on blood-brain barrier disruption. Ultrasound Med Biol (2007) 1.64
Viremia profiles in children with chronic hepatitis B virus infection and spontaneous e antigen seroconversion. Gastroenterology (2007) 1.63
Adiponectin enhances IL-6 production in human synovial fibroblast via an AdipoR1 receptor, AMPK, p38, and NF-kappa B pathway. J Immunol (2007) 1.59
Drosophila Melted modulates FOXO and TOR activity. Dev Cell (2005) 1.59
Clinical relevance of hepatitis B virus genotype in children with chronic infection and hepatocellular carcinoma. Gastroenterology (2004) 1.36
Polarized epithelial cells secrete matriptase as a consequence of zymogen activation and HAI-1-mediated inhibition. Am J Physiol Cell Physiol (2009) 1.27
Recombinase-mediated cassette exchange provides a versatile platform for gene targeting: knockout of miR-31b. Genetics (2009) 1.26
Leptin-induced IL-6 production is mediated by leptin receptor, insulin receptor substrate-1, phosphatidylinositol 3-kinase, Akt, NF-kappaB, and p300 pathway in microglia. J Immunol (2007) 1.24
Zymogen activation, inhibition, and ectodomain shedding of matriptase. Front Biosci (2008) 1.24
A new tool for measuring cup orientation in total hip arthroplasties from plain radiographs. Clin Orthop Relat Res (2006) 1.22
High glucose induces human endothelial cell apoptosis through a phosphoinositide 3-kinase-regulated cyclooxygenase-2 pathway. Arterioscler Thromb Vasc Biol (2005) 1.22
The alternative reading frame tumor suppressor antagonizes hypoxia-induced cancer cell migration via interaction with the COOH-terminal binding protein corepressor. Cancer Res (2007) 1.19
Thyroid carcinoma with bone metastases: a prognostic factor study. Clin Med Oncol (2008) 1.18
Ultrasound stimulates cyclooxygenase-2 expression and increases bone formation through integrin, focal adhesion kinase, phosphatidylinositol 3-kinase, and Akt pathway in osteoblasts. Mol Pharmacol (2006) 1.16
Osteopontin increases migration and MMP-9 up-regulation via alphavbeta3 integrin, FAK, ERK, and NF-kappaB-dependent pathway in human chondrosarcoma cells. J Cell Physiol (2009) 1.16
Effect of ultrasound contrast agent dose on the duration of focused-ultrasound-induced blood-brain barrier disruption. J Acoust Soc Am (2009) 1.15
Identification of a novel FN1-FGFR1 genetic fusion as a frequent event in phosphaturic mesenchymal tumour. J Pathol (2015) 1.14
Higher seroprevalence of Entamoeba histolytica infection is associated with human immunodeficiency virus type 1 infection in Taiwan. Am J Trop Med Hyg (2006) 1.11
Long-term tracking of hepatitis B viral load and the relationship with risk for hepatocellular carcinoma in men. Carcinogenesis (2007) 1.11
Effectiveness and limitations of hand hygiene promotion on decreasing healthcare-associated infections. PLoS One (2011) 1.10
Endoplasmic reticulum stress implicated in the development of renal fibrosis. Mol Med (2011) 1.09
Identification of three novel mutations in the GATA3 gene responsible for familial hypoparathyroidism and deafness in the Chinese population. J Clin Endocrinol Metab (2006) 1.09
Prostaglandin E2 stimulates fibronectin expression through EP1 receptor, phospholipase C, protein kinase Calpha, and c-Src pathway in primary cultured rat osteoblasts. J Biol Chem (2005) 1.09
Involvement of matrix metalloproteinase-9 in stromal cell-derived factor-1/CXCR4 pathway of lung cancer metastasis. Carcinogenesis (2007) 1.07
PPARgamma inhibits osteogenesis via the down-regulation of the expression of COX-2 and iNOS in rats. Bone (2007) 1.06
Effects of 24 h ultra-marathon on biochemical and hematological parameters. World J Gastroenterol (2004) 1.05
Arsenic induces pancreatic β-cell apoptosis via the oxidative stress-regulated mitochondria-dependent and endoplasmic reticulum stress-triggered signaling pathways. Toxicol Lett (2010) 1.02
Body-mass index and progression of hepatitis B: a population-based cohort study in men. J Clin Oncol (2008) 1.02
Cancer risk in HBV patients with statin and metformin use: a population-based cohort study. Medicine (Baltimore) (2015) 1.02
Thrombin-induced IL-6 production in human synovial fibroblasts is mediated by PAR1, phospholipase C, protein kinase C alpha, c-Src, NF-kappa B and p300 pathway. Mol Immunol (2007) 1.00
Ultrasound induces cyclooxygenase-2 expression through integrin, integrin-linked kinase, Akt, NF-kappaB and p300 pathway in human chondrocytes. Cell Signal (2007) 1.00
Effects on function and quality of life of postoperative home-based physical therapy for patients with hip fracture. Arch Phys Med Rehabil (2005) 1.00
Effects of exercise programmes on quality of life in osteoporotic and osteopenic postmenopausal women: a systematic review and meta-analysis. Clin Rehabil (2009) 1.00
Apoptosis of cultured astrocytes induced by the copper and neocuproine complex through oxidative stress and JNK activation. Toxicol Sci (2007) 0.99
Honokiol induces cell apoptosis in human chondrosarcoma cells through mitochondrial dysfunction and endoplasmic reticulum stress. Cancer Lett (2009) 0.99
Involvement of oxidative stress-mediated ERK1/2 and p38 activation regulated mitochondria-dependent apoptotic signals in methylmercury-induced neuronal cell injury. Toxicol Lett (2011) 0.99
A pilot randomized controlled trial to improve geriatric frailty. BMC Geriatr (2012) 0.99
Stromal cell-derived factor-1 increase alphavbeta3 integrin expression and invasion in human chondrosarcoma cells. J Cell Physiol (2009) 0.99
Treatment of unicameral bone cyst: a comparative study of selected techniques. J Bone Joint Surg Am (2010) 0.98
Osteoblasts-derived BMP-2 enhances the motility of prostate cancer cells via activation of integrins. Prostate (2008) 0.98
beta-Lapachone reduces endotoxin-induced macrophage activation and lung edema and mortality. Am J Respir Crit Care Med (2003) 0.98
Lack of independent relationship between plasma adiponectin, leptin levels and bone density in nondiabetic female adolescents. Clin Endocrinol (Oxf) (2004) 0.96
Stromal cell-derived factor-1 induces matrix metalloprotease-13 expression in human chondrocytes. Mol Pharmacol (2007) 0.96
MicroRNA transgene overexpression complements deficiency-based modifier screens in Drosophila. Genetics (2011) 0.96
Tissue distribution of different mercurial compounds analyzed by the improved FI-CVAAS. J Anal Toxicol (2002) 0.96
The diagnostic and prognostic effectiveness of F-18 sodium fluoride PET-CT in detecting bone metastases for hepatocellular carcinoma patients. Nucl Med Commun (2010) 0.96
Neurotoxicological effects of cinnabar (a Chinese mineral medicine, HgS) in mice. Toxicol Appl Pharmacol (2007) 0.96
Measurement of the acetabular cup anteversion on simulated radiographs. J Arthroplasty (2008) 0.95
Ultrasound induces hypoxia-inducible factor-1 activation and inducible nitric-oxide synthase expression through the integrin/integrin-linked kinase/Akt/mammalian target of rapamycin pathway in osteoblasts. J Biol Chem (2007) 0.95
Prevalence of dyslipidemia and mean blood lipid values in Taiwan: results from the Nutrition and Health Survey in Taiwan (NAHSIT, 1993-1996). Chin J Physiol (2002) 0.94
The effects of sensorimotor training on knee proprioception and function for patients with knee osteoarthritis: a preliminary report. Clin Rehabil (2008) 0.93
Arsenic induces apoptosis in myoblasts through a reactive oxygen species-induced endoplasmic reticulum stress and mitochondrial dysfunction pathway. Arch Toxicol (2012) 0.93
Hepatitis B virus core variants modify natural course of viral infection and hepatocellular carcinoma progression. Gastroenterology (2009) 0.92
Mechanisms for the control of matriptase activity in the absence of sufficient HAI-1. Am J Physiol Cell Physiol (2011) 0.92
Cadmium induces apoptosis in pancreatic β-cells through a mitochondria-dependent pathway: the role of oxidative stress-mediated c-Jun N-terminal kinase activation. PLoS One (2013) 0.92
Arsenic induces reactive oxygen species-caused neuronal cell apoptosis through JNK/ERK-mediated mitochondria-dependent and GRP 78/CHOP-regulated pathways. Toxicol Lett (2013) 0.92
Osteoblast-derived TGF-beta1 stimulates IL-8 release through AP-1 and NF-kappaB in human cancer cells. J Bone Miner Res (2008) 0.92
Atypical femoral fractures shortly after osteonecrosis of the jaw in a postmenopausal woman taking alendronate for osteoporosis. J Clin Endocrinol Metab (2013) 0.92
Structural insights into the Notch-modifying glycosyltransferase Fringe. Nat Struct Mol Biol (2006) 0.92
A 12-year ecological study of hip fracture rates among older Taiwanese adults. Calcif Tissue Int (2013) 0.91
C/EBP homologous protein (CHOP) deficiency aggravates hippocampal cell apoptosis and impairs memory performance. PLoS One (2012) 0.91
The in vivo antioxidant and antifibrotic properties of green tea (Camellia sinensis, Theaceae). Food Chem (2012) 0.91
Image changes of paraspinal muscles and clinical correlations in patients with unilateral lumbar spinal stenosis. Eur Spine J (2014) 0.90
Analgesic and Antiinflammatory Activities of the Aqueous Extract from Plectranthus amboinicus (Lour.) Spreng. Both In Vitro and In Vivo. Evid Based Complement Alternat Med (2011) 0.90
The oscillating miRNA 959-964 cluster impacts Drosophila feeding time and other circadian outputs. Cell Metab (2012) 0.90
Upregulation of heme oxygenase-1 inhibits the maturation and mineralization of osteoblasts. J Cell Physiol (2010) 0.89
Similar local control between phenol- and ethanol-treated giant cell tumors of bone. Clin Orthop Relat Res (2011) 0.89
Clinical practice guidelines for the prevention and treatment of osteoporosis in Taiwan: summary. J Bone Miner Metab (2013) 0.89
Basic fibroblast growth factor stimulates fibronectin expression through phospholipase C gamma, protein kinase C alpha, c-Src, NF-kappaB, and p300 pathway in osteoblasts. J Cell Physiol (2007) 0.89
Risk factors for single and recurrent falls: a prospective study of falls in community dwelling seniors without cognitive impairment. Prev Med (2013) 0.89
Increased matriptase zymogen activation in inflammatory skin disorders. Am J Physiol Cell Physiol (2010) 0.89
Endonuclease V-mediated deoxyinosine excision repair in vitro. DNA Repair (Amst) (2010) 0.89
Regulation of the maturation of osteoblasts and osteoclastogenesis by glutamate. Eur J Pharmacol (2008) 0.89
Neurotoxicological mechanism of methylmercury induced by low-dose and long-term exposure in mice: oxidative stress and down-regulated Na+/K(+)-ATPase involved. Toxicol Lett (2007) 0.89
Septic arthritis of the hip joint in cervical cancer patients after radiotherapy: Three case reports. J Orthop Surg (Hong Kong) (2001) 0.88
Enhancement of bone morphogenetic protein-2 expression and bone formation by coumarin derivatives via p38 and ERK-dependent pathway in osteoblasts. Eur J Pharmacol (2007) 0.88
High prevalence of hyperuricemia in elderly Taiwanese. Asia Pac J Clin Nutr (2005) 0.88
Arsenic induces cell apoptosis in cultured osteoblasts through endoplasmic reticulum stress. Toxicol Appl Pharmacol (2009) 0.88
Caffeic acid phenethyl ester suppresses proliferation and survival of TW2.6 human oral cancer cells via inhibition of Akt signaling. Int J Mol Sci (2013) 0.88
Use of motor abundance in old adults in the regulation of a narrow-based stance. Eur J Appl Physiol (2013) 0.87
Effects of arsenic on osteoblast differentiation in vitro and on bone mineral density and microstructure in rats. Environ Health Perspect (2014) 0.87