Published in Nat Struct Mol Biol on September 10, 2006
The molecular logic of Notch signaling--a structural and biochemical perspective. J Cell Sci (2008) 1.65
The Actinobacillus pleuropneumoniae HMW1C-like glycosyltransferase mediates N-linked glycosylation of the Haemophilus influenzae HMW1 adhesin. PLoS One (2010) 0.98
The human collagen beta(1-O)galactosyltransferase, GLT25D1, is a soluble endoplasmic reticulum localized protein. BMC Cell Biol (2010) 0.92
The highly conserved domain of unknown function 1792 has a distinct glycosyltransferase fold. Nat Commun (2014) 0.89
Positional cloning of a Bombyx wingless locus flugellos (fl) reveals a crucial role for fringe that is specific for wing morphogenesis. Genetics (2008) 0.89
Structural and mechanistic insights into lunatic fringe from a kinetic analysis of enzyme mutants. J Biol Chem (2008) 0.80
Chondroitin sulfate synthase-2/chondroitin polymerizing factor has two variants with distinct function. J Biol Chem (2010) 0.80
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Biochemical characterization of functional domains of the chaperone Cosmc. PLoS One (2017) 0.75
Principles of microRNA-target recognition. PLoS Biol (2005) 23.70
bantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in Drosophila. Cell (2003) 22.14
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Animal MicroRNAs confer robustness to gene expression and have a significant impact on 3'UTR evolution. Cell (2005) 15.38
Identification of Drosophila MicroRNA targets. PLoS Biol (2003) 12.72
Isolation of microRNA targets by miRNP immunopurification. RNA (2007) 5.50
Drosophila's insulin/PI3-kinase pathway coordinates cellular metabolism with nutritional conditions. Dev Cell (2002) 4.85
A single subunit, Dis3, is essentially responsible for yeast exosome core activity. Nat Struct Mol Biol (2006) 4.84
Structural basis of Aurora-A activation by TPX2 at the mitotic spindle. Mol Cell (2003) 4.51
The conserved microRNA miR-8 tunes atrophin levels to prevent neurodegeneration in Drosophila. Cell (2007) 4.00
Structure of a Survivin-Borealin-INCENP core complex reveals how chromosomal passengers travel together. Cell (2007) 3.98
The Hippo pathway regulates the bantam microRNA to control cell proliferation and apoptosis in Drosophila. Cell (2006) 3.81
Genome-wide analysis of mRNAs regulated by Drosha and Argonaute proteins in Drosophila melanogaster. Mol Cell Biol (2006) 3.80
Structural biology of nucleocytoplasmic transport. Annu Rev Biochem (2007) 3.66
The crystal structure of the exon junction complex reveals how it maintains a stable grip on mRNA. Cell (2006) 3.51
The archaeal exosome core is a hexameric ring structure with three catalytic subunits. Nat Struct Mol Biol (2005) 3.07
Tumor suppressor properties of the ESCRT-II complex component Vps25 in Drosophila. Dev Cell (2005) 2.81
SMG7 is a 14-3-3-like adaptor in the nonsense-mediated mRNA decay pathway. Mol Cell (2005) 2.71
Polypeptide GalNAc-transferase T3 and familial tumoral calcinosis. Secretion of fibroblast growth factor 23 requires O-glycosylation. J Biol Chem (2006) 2.68
On the mechanism of wing size determination in fly development. Proc Natl Acad Sci U S A (2007) 2.62
Precision mapping of the human O-GalNAc glycoproteome through SimpleCell technology. EMBO J (2013) 2.58
Control of mucin-type O-glycosylation: a classification of the polypeptide GalNAc-transferase gene family. Glycobiology (2011) 2.56
Mei-P26 regulates microRNAs and cell growth in the Drosophila ovarian stem cell lineage. Nature (2008) 2.54
MicroRNAs and gene regulatory networks: managing the impact of noise in biological systems. Genes Dev (2010) 2.51
Temporal reciprocity of miRNAs and their targets during the maternal-to-zygotic transition in Drosophila. Curr Biol (2008) 2.47
A single Hox locus in Drosophila produces functional microRNAs from opposite DNA strands. Genes Dev (2008) 2.45
The yeast exosome functions as a macromolecular cage to channel RNA substrates for degradation. Cell (2009) 2.43
Bacterial glycosidases for the production of universal red blood cells. Nat Biotechnol (2007) 2.41
The superhelical TPR-repeat domain of O-linked GlcNAc transferase exhibits structural similarities to importin alpha. Nat Struct Mol Biol (2004) 2.36
Nutritional control of protein biosynthetic capacity by insulin via Myc in Drosophila. Cell Metab (2008) 2.32
Molecular mechanisms for the RNA-dependent ATPase activity of Upf1 and its regulation by Upf2. Mol Cell (2011) 2.31
4E-BP functions as a metabolic brake used under stress conditions but not during normal growth. Genes Dev (2005) 2.28
Drosophila lacking microRNA miR-278 are defective in energy homeostasis. Genes Dev (2006) 2.26
Structure of the active subunit of the yeast exosome core, Rrp44: diverse modes of substrate recruitment in the RNase II nuclease family. Mol Cell (2008) 2.22
Regulation of tissue growth through nutrient sensing. Annu Rev Genet (2009) 2.18
Glycosylation restores survival of chilled blood platelets. Science (2003) 2.18
Structures of the PIN domains of SMG6 and SMG5 reveal a nuclease within the mRNA surveillance complex. EMBO J (2006) 2.16
A novel mode of RBD-protein recognition in the Y14-Mago complex. Nat Struct Biol (2003) 2.11
HSPG modification by the secreted enzyme Notum shapes the Wingless morphogen gradient. Dev Cell (2002) 2.03
The growth regulators warts/lats and melted interact in a bistable loop to specify opposite fates in Drosophila R8 photoreceptors. Cell (2005) 2.00
Connecting proliferation and apoptosis in development and disease. Nat Rev Mol Cell Biol (2004) 1.97
Mining the O-glycoproteome using zinc-finger nuclease-glycoengineered SimpleCell lines. Nat Methods (2011) 1.92
Krüppel-like factor 4, a tumor suppressor in hepatocellular carcinoma cells reverts epithelial mesenchymal transition by suppressing slug expression. PLoS One (2012) 1.87
Seromic profiling of colorectal cancer patients with novel glycopeptide microarray. Int J Cancer (2011) 1.84
Re-evaluating AKT regulation: role of TOR complex 2 in tissue growth. Genes Dev (2007) 1.83
microRNA miR-14 acts to modulate a positive autoregulatory loop controlling steroid hormone signaling in Drosophila. Genes Dev (2007) 1.80
Cancer biomarkers defined by autoantibody signatures to aberrant O-glycopeptide epitopes. Cancer Res (2010) 1.79
Stable kinetochore-microtubule interactions depend on the Ska complex and its new component Ska3/C13Orf3. EMBO J (2009) 1.76
Crystal structure of an RNA-bound 11-subunit eukaryotic exosome complex. Nature (2013) 1.74
Wingless and Notch signaling provide cell survival cues and control cell proliferation during wing development. Development (2003) 1.72
Mucin-type O-glycosylation and its potential use in drug and vaccine development. Biochim Biophys Acta (2007) 1.70
Opposing activities of Dally-like glypican at high and low levels of Wingless morphogen activity. Dev Cell (2004) 1.69
Structural basis of 3' end RNA recognition and exoribonucleolytic cleavage by an exosome RNase PH core. Mol Cell (2005) 1.68
The mRNA export protein DBP5 binds RNA and the cytoplasmic nucleoporin NUP214 in a mutually exclusive manner. Nat Struct Mol Biol (2009) 1.68
Location, location, location: new insights into O-GalNAc protein glycosylation. Trends Cell Biol (2010) 1.65
RNA channelling by the archaeal exosome. EMBO Rep (2007) 1.62
The bantam gene regulates Drosophila growth. Genetics (2002) 1.62
MicroRNAs in neurodegeneration. Curr Opin Neurobiol (2008) 1.62
Drosophila Melted modulates FOXO and TOR activity. Dev Cell (2005) 1.59
The ST6GalNAc-I sialyltransferase localizes throughout the Golgi and is responsible for the synthesis of the tumor-associated sialyl-Tn O-glycan in human breast cancer. J Biol Chem (2005) 1.59
Short-range cell interactions and cell survival in the Drosophila wing. Dev Cell (2002) 1.57
Repeated infusions of donor-derived cytokine-induced killer cells in patients relapsing after allogeneic stem cell transplantation: a phase I study. Haematologica (2007) 1.54
Chemoenzymatically synthesized multimeric Tn/STn MUC1 glycopeptides elicit cancer-specific anti-MUC1 antibody responses and override tolerance. Glycobiology (2005) 1.50
Towards a complete description of the microRNA complement of animal genomes. Genome Biol (2003) 1.49
O-glycosylation modulates proprotein convertase activation of angiopoietin-like protein 3: possible role of polypeptide GalNAc-transferase-2 in regulation of concentrations of plasma lipids. J Biol Chem (2010) 1.46
Assessing calibration uncertainty in molecular dating: the assignment of fossils to alternative calibration points. Syst Biol (2007) 1.43
Islands as model systems in ecology and evolution: prospects fifty years after MacArthur-Wilson. Ecol Lett (2015) 1.41
A systematic study of site-specific GalNAc-type O-glycosylation modulating proprotein convertase processing. J Biol Chem (2011) 1.40
Tracing the temporal and spatial origins of island endemics in the Mediterranean region: a case study from the citrus family (Ruta L., Rutaceae). Syst Biol (2010) 1.39
Pilot study of a heptavalent vaccine-keyhole limpet hemocyanin conjugate plus QS21 in patients with epithelial ovarian, fallopian tube, or peritoneal cancer. Clin Cancer Res (2007) 1.39
Slik Sterile-20 kinase regulates Moesin activity to promote epithelial integrity during tissue growth. Genes Dev (2004) 1.38
Evolutionary biology in biodiversity science, conservation, and policy: a call to action. Evolution (2010) 1.36
Site-specific protein O-glycosylation modulates proprotein processing - deciphering specific functions of the large polypeptide GalNAc-transferase gene family. Biochim Biophys Acta (2012) 1.36
Identification of a novel cancer-specific immunodominant glycopeptide epitope in the MUC1 tandem repeat. Glycobiology (2006) 1.35
Are any primroses (Primula) primitively monomorphic? New Phytol (2006) 1.31
Phylogenetic relationships of Ruteae (Rutaceae): new evidence from the chloroplast genome and comparisons with non-molecular data. Mol Phylogenet Evol (2008) 1.29
Aberrant expression of mucin core proteins and o-linked glycans associated with progression of pancreatic cancer. Clin Cancer Res (2013) 1.28
Identification of novel Drosophila melanogaster microRNAs. PLoS One (2007) 1.28
Mining the O-mannose glycoproteome reveals cadherins as major O-mannosylated glycoproteins. Proc Natl Acad Sci U S A (2013) 1.27
Polarized epithelial cells secrete matriptase as a consequence of zymogen activation and HAI-1-mediated inhibition. Am J Physiol Cell Physiol (2009) 1.27
Immunopurification of Ago1 miRNPs selects for a distinct class of microRNA targets. Proc Natl Acad Sci U S A (2009) 1.26
Tumor-associated Tn-MUC1 glycoform is internalized through the macrophage galactose-type C-type lectin and delivered to the HLA class I and II compartments in dendritic cells. Cancer Res (2007) 1.26
Recombinase-mediated cassette exchange provides a versatile platform for gene targeting: knockout of miR-31b. Genetics (2009) 1.26
Initiation of GalNAc-type O-glycosylation in the endoplasmic reticulum promotes cancer cell invasiveness. Proc Natl Acad Sci U S A (2013) 1.26
Drosophila microRNAs 263a/b confer robustness during development by protecting nascent sense organs from apoptosis. PLoS Biol (2010) 1.26
Arabidopsis thaliana RGXT1 and RGXT2 encode Golgi-localized (1,3)-alpha-D-xylosyltransferases involved in the synthesis of pectic rhamnogalacturonan-II. Plant Cell (2006) 1.25
Structural analysis reveals the characteristic features of Mtr4, a DExH helicase involved in nuclear RNA processing and surveillance. Proc Natl Acad Sci U S A (2010) 1.25
Phylogenetic relationships within Senna (Leguminosae, Cassiinae) based on three chloroplast DNA regions: patterns in the evolution of floral symmetry and extrafloral nectaries. Am J Bot (2006) 1.24
Zymogen activation, inhibition, and ectodomain shedding of matriptase. Front Biosci (2008) 1.24
Architecture of the nuclease module of the yeast Ccr4-not complex: the Not1-Caf1-Ccr4 interaction. Mol Cell (2012) 1.24
MAP4K3 regulates body size and metabolism in Drosophila. Dev Biol (2010) 1.24
Role of the human ST6GalNAc-I and ST6GalNAc-II in the synthesis of the cancer-associated sialyl-Tn antigen. Cancer Res (2004) 1.23
Structures of the tRNA export factor in the nuclear and cytosolic states. Nature (2009) 1.23
Probing isoform-specific functions of polypeptide GalNAc-transferases using zinc finger nuclease glycoengineered SimpleCells. Proc Natl Acad Sci U S A (2012) 1.22
The lectin domains of polypeptide GalNAc-transferases exhibit carbohydrate-binding specificity for GalNAc: lectin binding to GalNAc-glycopeptide substrates is required for high density GalNAc-O-glycosylation. Glycobiology (2007) 1.21