The p75 neurotrophin receptor, semaphorins, and sympathetic traffic in the heart.

PubWeight™: 0.76‹?›

🔗 View Article (PMC 2886656)

Published in Am J Physiol Heart Circ Physiol on March 19, 2010

Authors

Bruce D Carter, Ning Feng, Nazareno Paolocci

Articles cited by this

The sympathetic nervous system in heart failure physiology, pathophysiology, and clinical implications. J Am Coll Cardiol (2009) 3.55

A neurotrophin signaling cascade coordinates sympathetic neuron development through differential control of TrkA trafficking and retrograde signaling. Cell (2004) 3.38

Neurotrophin signalling in health and disease. Clin Sci (Lond) (2006) 2.85

Developmental axon pruning mediated by BDNF-p75NTR-dependent axon degeneration. Nat Neurosci (2008) 2.61

Relationship between regional cardiac hyperinnervation and ventricular arrhythmia. Circulation (2000) 2.44

Brain derived neurotrophic factor is an endothelial cell survival factor required for intramyocardial vessel stabilization. Development (2000) 2.18

Sema3a maintains normal heart rhythm through sympathetic innervation patterning. Nat Med (2007) 2.16

MAG induces regulated intramembrane proteolysis of the p75 neurotrophin receptor to inhibit neurite outgrowth. Neuron (2005) 2.15

Growth and survival signals controlling sympathetic nervous system development. Annu Rev Neurosci (2005) 2.11

The p75 neurotrophin receptor mediates neuronal apoptosis and is essential for naturally occurring sympathetic neuron death. J Cell Biol (1998) 1.90

Parasympathetic nervous system and heart failure: pathophysiology and potential implications for therapy. Circulation (2008) 1.83

Novel mechanisms of sympathetic regulation in chronic heart failure. Hypertension (2006) 1.66

Injection of nerve growth factor into stellate ganglia improves norepinephrine reuptake into failing hearts. Hypertension (2005) 1.49

Low-affinity nerve growth factor receptor p75NTR immunoreactivity in the myocardium with sympathetic hyperinnervation. J Cardiovasc Electrophysiol (2004) 1.46

Cardiovascular actions of neurotrophins. Physiol Rev (2009) 1.45

Functionally antagonistic interactions between the TrkA and p75 neurotrophin receptors regulate sympathetic neuron growth and target innervation. J Neurosci (1999) 1.40

Identification of the prosurvival activity of nerve growth factor on cardiac myocytes. Cell Death Differ (2007) 1.39

Cardiac autonomic neural remodeling and susceptibility to sudden cardiac death: effect of endurance exercise training. Am J Physiol Heart Circ Physiol (2009) 1.35

The p75 neurotrophin receptor: multiple interactors and numerous functions. Prog Brain Res (2004) 1.26

TrkB signaling is required for postnatal survival of CNS neurons and protects hippocampal and motor neurons from axotomy-induced cell death. J Neurosci (1997) 1.25

Regulation of human leukocyte beta receptors by endogenous catecholamines: relationship of leukocyte beta receptor density to the cardiac sensitivity to isoproterenol. J Clin Invest (1981) 1.23

Nerve growth factor modulates synaptic transmission between sympathetic neurons and cardiac myocytes. J Neurosci (1997) 1.22

Sympathetic nerve biology in essential hypertension. Clin Exp Pharmacol Physiol (2001) 1.21

Response of failing canine and human heart cells to beta 2-adrenergic stimulation. Circulation (1995) 1.18

Overexpression of NGF within the heart of transgenic mice causes hyperinnervation, cardiac enlargement, and hyperplasia of ectopic cells. Dev Biol (1995) 1.15

The cardiac hERG/IKr potassium channel as pharmacological target: structure, function, regulation, and clinical applications. Curr Pharm Des (2006) 1.12

A neural set point for the long-term control of arterial pressure: beyond the arterial baroreceptor reflex. Am J Physiol Regul Integr Comp Physiol (2005) 1.11

Deficiency of M2 muscarinic acetylcholine receptors increases susceptibility of ventricular function to chronic adrenergic stress. Am J Physiol Heart Circ Physiol (2007) 1.05

Identification of Nogo as a novel indicator of heart failure. Physiol Genomics (2007) 1.03

Differential expression of cardiac neurotrophic factors and sympathetic nerve ending abnormalities within the failing heart. J Mol Cell Cardiol (2007) 0.99

Modulation of semaphorin3A activity by p75 neurotrophin receptor influences peripheral axon patterning. J Neurosci (2007) 0.98

Heterogeneous ventricular sympathetic innervation, altered beta-adrenergic receptor expression, and rhythm instability in mice lacking the p75 neurotrophin receptor. Am J Physiol Heart Circ Physiol (2010) 0.96

Cholinergic neurons of mouse intrinsic cardiac ganglia contain noradrenergic enzymes, norepinephrine transporters, and the neurotrophin receptors tropomyosin-related kinase A and p75. Neuroscience (2008) 0.94

Something old, something new: BDNF-induced neuron survival requires TRPC channel function. Nat Neurosci (2007) 0.91

The influences of p75 neurotrophin receptor and brain-derived neurotrophic factor in the sympathetic innervation of target tissues during murine postnatal development. Auton Neurosci (2005) 0.91

Regulation of cardiac innervation and function via the p75 neurotrophin receptor. Auton Neurosci (2008) 0.91

Influences of autonomic nervous system on atrial arrhythmogenic substrates and the incidence of atrial fibrillation in diabetic heart. Int Heart J (2009) 0.90

Nerve growth factor collaborates with myocyte-derived factors to promote development of presynaptic sites in cultured sympathetic neurons. J Neurobiol (2000) 0.87

Neurite outgrowth elicited by embryonic chick heart: partial purification of the active factor. Neurosci Lett (1979) 0.86

VEGF-A and Semaphorin3A: modulators of vascular sympathetic innervation. Dev Biol (2009) 0.86

Nerve growth factor-mediated induction of tyrosine hydroxylase in rat superior cervical ganglia in vitro. J Biol Chem (1978) 0.86

A novel cardiac hypertrophic factor, neurotrophin-3, is paradoxically downregulated in cardiac hypertrophy. Life Sci (2007) 0.85

TrkA and mitogen-activated protein kinase phosphorylation are enhanced in sympathetic neurons lacking functional p75 neurotrophin receptor expression. Eur J Neurosci (2004) 0.83

What have we learned about the contribution of autonomic nervous system to human arrhythmia? Heart Rhythm (2009) 0.81

Sympathetic nervous system neuroplasticity. Hypertension (2006) 0.81

Target derived and putative local actions of neurotrophins in the peripheral nervous system. Prog Brain Res (1994) 0.78

Retrograde control of neural circuit formation. Cell (2006) 0.76

Articles by these authors

Neuronal apoptosis linked to EglN3 prolyl hydroxylase and familial pheochromocytoma genes: developmental culling and cancer. Cancer Cell (2005) 3.51

Oxidant stress from nitric oxide synthase-3 uncoupling stimulates cardiac pathologic remodeling from chronic pressure load. J Clin Invest (2005) 3.22

The chemical biology of nitric oxide: implications in cellular signaling. Free Radic Biol Med (2008) 2.72

High-dose folic acid pretreatment blunts cardiac dysfunction during ischemia coupled to maintenance of high-energy phosphates and reduces postreperfusion injury. Circulation (2008) 2.47

Activation of the transcription factor NF-kappaB in Schwann cells is required for peripheral myelin formation. Nat Neurosci (2003) 2.19

Activation of the p75 neurotrophin receptor through conformational rearrangement of disulphide-linked receptor dimers. Neuron (2009) 1.96

The kinesin KIF1Bbeta acts downstream from EglN3 to induce apoptosis and is a potential 1p36 tumor suppressor. Genes Dev (2008) 1.93

Compartmentalized phosphodiesterase-2 activity blunts beta-adrenergic cardiac inotropy via an NO/cGMP-dependent pathway. Circ Res (2005) 1.91

Junctional adhesion molecule-A is required for hematogenous dissemination of reovirus. Cell Host Microbe (2009) 1.91

Reversal of cardiac hypertrophy and fibrosis from pressure overload by tetrahydrobiopterin: efficacy of recoupling nitric oxide synthase as a therapeutic strategy. Circulation (2008) 1.82

A biochemical rationale for the discrete behavior of nitroxyl and nitric oxide in the cardiovascular system. Proc Natl Acad Sci U S A (2003) 1.78

Ligand-dependent cleavage of the P75 neurotrophin receptor is necessary for NRIF nuclear translocation and apoptosis in sympathetic neurons. Neuron (2006) 1.74

Cardioprotective effect of beta-3 adrenergic receptor agonism: role of neuronal nitric oxide synthase. J Am Coll Cardiol (2012) 1.72

Imbalance between xanthine oxidase and nitric oxide synthase signaling pathways underlies mechanoenergetic uncoupling in the failing heart. Circ Res (2002) 1.70

Nitroxyl improves cellular heart function by directly enhancing cardiac sarcoplasmic reticulum Ca2+ cycling. Circ Res (2006) 1.56

Glial precursors clear sensory neuron corpses during development via Jedi-1, an engulfment receptor. Nat Neurosci (2009) 1.54

Expression, activity, and pro-hypertrophic effects of PDE5A in cardiac myocytes. Cell Signal (2008) 1.44

(R)-Profens are substrate-selective inhibitors of endocannabinoid oxygenation by COX-2. Nat Chem Biol (2011) 1.39

The chemistry of nitrosative stress induced by nitric oxide and reactive nitrogen oxide species. Putting perspective on stressful biological situations. Biol Chem (2004) 1.37

Thioredoxin reductase-2 is essential for keeping low levels of H(2)O(2) emission from isolated heart mitochondria. J Biol Chem (2011) 1.35

Protein kinase A-induced phosphorylation of the p65 subunit of nuclear factor-kappaB promotes Schwann cell differentiation into a myelinating phenotype. J Neurosci (2008) 1.34

Modulation of mitochondrial proteome and improved mitochondrial function by biventricular pacing of dyssynchronous failing hearts. Circ Cardiovasc Genet (2009) 1.32

Monoamine oxidase A-mediated enhanced catabolism of norepinephrine contributes to adverse remodeling and pump failure in hearts with pressure overload. Circ Res (2009) 1.32

Nitroxyl increases force development in rat cardiac muscle. J Physiol (2007) 1.30

Nitroxyl affords thiol-sensitive myocardial protective effects akin to early preconditioning. Free Radic Biol Med (2003) 1.28

The p75 neurotrophin receptor: multiple interactors and numerous functions. Prog Brain Res (2004) 1.26

Comparison of the NO and HNO donating properties of diazeniumdiolates: primary amine adducts release HNO in Vivo. J Med Chem (2005) 1.26

Creatine kinase-mediated improvement of function in failing mouse hearts provides causal evidence the failing heart is energy starved. J Clin Invest (2011) 1.26

The physiological chemistry and biological activity of nitroxyl (HNO): the neglected, misunderstood, and enigmatic nitrogen oxide. Chem Res Toxicol (2005) 1.24

TRAF6-mediated ubiquitination regulates nuclear translocation of NRIF, the p75 receptor interactor. EMBO J (2005) 1.22

Mechanism of aerobic decomposition of Angeli's salt (sodium trioxodinitrate) at physiological pH. J Am Chem Soc (2005) 1.22

Guide for the use of nitric oxide (NO) donors as probes of the chemistry of NO and related redox species in biological systems. Methods Enzymol (2002) 1.20

Induction of proneurotrophins and activation of p75NTR-mediated apoptosis via neurotrophin receptor-interacting factor in hippocampal neurons after seizures. J Neurosci (2008) 1.19

Phospholamban thiols play a central role in activation of the cardiac muscle sarcoplasmic reticulum calcium pump by nitroxyl. Biochemistry (2008) 1.16

Orthogonal properties of the redox siblings nitroxyl and nitric oxide in the cardiovascular system: a novel redox paradigm. Am J Physiol Heart Circ Physiol (2003) 1.15

Monoamine oxidases (MAO) in the pathogenesis of heart failure and ischemia/reperfusion injury. Biochim Biophys Acta (2010) 1.13

Glutathione/thioredoxin systems modulate mitochondrial H2O2 emission: an experimental-computational study. J Gen Physiol (2012) 1.13

Neurotrophin signaling through the p75 receptor is deficient in traf6-/- mice. J Neurosci (2004) 1.11

p75 neurotrophin receptor-mediated apoptosis in sympathetic neurons involves a biphasic activation of JNK and up-regulation of tumor necrosis factor-alpha-converting enzyme/ADAM17. J Biol Chem (2010) 1.09

Serum paraoxonase: effect of the apolipoprotein composition of HDL and the acute phase response. J Lipid Res (2003) 1.09

Peroxynitrite and myocardial contractility: in vivo versus in vitro effects. Free Radic Biol Med (2006) 1.08

Playing with cardiac "redox switches": the "HNO way" to modulate cardiac function. Antioxid Redox Signal (2011) 1.07

Abnormal junctions and permeability of myelin in PMP22-deficient nerves. Ann Neurol (2014) 1.06

Monoamine oxidase B prompts mitochondrial and cardiac dysfunction in pressure overloaded hearts. Antioxid Redox Signal (2013) 1.04

The specificity of nitroxyl chemistry is unique among nitrogen oxides in biological systems. Antioxid Redox Signal (2011) 1.04

Discriminating formation of HNO from other reactive nitrogen oxide species. Free Radic Biol Med (2005) 1.03

GSH or palmitate preserves mitochondrial energetic/redox balance, preventing mechanical dysfunction in metabolically challenged myocytes/hearts from type 2 diabetic mice. Diabetes (2012) 1.03

Nitroxyl-mediated disulfide bond formation between cardiac myofilament cysteines enhances contractile function. Circ Res (2012) 1.02

Neurotrophin receptor interacting factor (NRIF) is an essential mediator of apoptotic signaling by the p75 neurotrophin receptor. J Biol Chem (2005) 1.01

Comparison of the reactivity of nitric oxide and nitroxyl with heme proteins. A chemical discussion of the differential biological effects of these redox related products of NOS. J Inorg Biochem (2003) 1.00

Calcitonin gene-related peptide in vivo positive inotropy is attributable to regional sympatho-stimulation and is blunted in congestive heart failure. Circ Res (2004) 0.99

Ligand-independent signaling by disulfide-crosslinked dimers of the p75 neurotrophin receptor. J Cell Sci (2009) 0.99

Influence of apoA-I and apoE on the formation of serum amyloid A-containing lipoproteins in vivo and in vitro. J Lipid Res (2003) 0.99

The emergence of nitroxyl (HNO) as a pharmacological agent. Biochim Biophys Acta (2009) 0.98

NF-κB forms a complex with the chromatin remodeler BRG1 to regulate Schwann cell differentiation. J Neurosci (2013) 0.98

Axonal neuregulin 1 type III activates NF-kappaB in Schwann cells during myelin formation. J Biol Chem (2010) 0.98

Examining nitroxyl in biological systems. Methods Enzymol (2008) 0.98

Jedi-1 and MEGF10 signal engulfment of apoptotic neurons through the tyrosine kinase Syk. J Neurosci (2012) 0.97

A functional interaction between the p75 neurotrophin receptor interacting factors, TRAF6 and NRIF. J Biol Chem (2004) 0.95

Mutation analysis of HIF prolyl hydroxylases (PHD/EGLN) in individuals with features of phaeochromocytoma and renal cell carcinoma susceptibility. Endocr Relat Cancer (2010) 0.95

Inhibiting metalloproteases with PD 166793 in heart failure: impact on cardiac remodeling and beyond. Cardiovasc Ther (2008) 0.94

miR-153 regulates SNAP-25, synaptic transmission, and neuronal development. PLoS One (2013) 0.92

p75 neurotrophin receptor cleavage by α- and γ-secretases is required for neurotrophin-mediated proliferation of brain tumor-initiating cells. J Biol Chem (2014) 0.91

Brain-derived neurotrophic factor (BDNF) induces polarized signaling of small GTPase (Rac1) protein at the onset of Schwann cell myelination through partitioning-defective 3 (Par3) protein. J Biol Chem (2011) 0.90

Reversible folding of human peripheral myelin protein 22, a tetraspan membrane protein. Biochemistry (2013) 0.89

Acyloxy nitroso compounds inhibit LIF signaling in endothelial cells and cardiac myocytes: evidence that STAT3 signaling is redox-sensitive. PLoS One (2012) 0.88

The chemical dynamics of NO and reactive nitrogen oxides: a practical guide. Curr Mol Med (2004) 0.87

Hydrogen sulfide [corrected] increases survival during sepsis: protective effect of CHOP inhibition. J Immunol (2014) 0.86

A novel role for PTEN in the inhibition of neurite outgrowth by myelin-associated glycoprotein in cortical neurons. Mol Cell Neurosci (2010) 0.86

HNO enhances SERCA2a activity and cardiomyocyte function by promoting redox-dependent phospholamban oligomerization. Antioxid Redox Signal (2013) 0.86

Nitroxyl enhances myocyte Ca2+ transients by exclusively targeting SR Ca2+-cycling. Front Biosci (Elite Ed) (2010) 0.86

Mother was right: eat your vegetables and do not spit! When oral nitrate helps with high blood pressure. Hypertension (2008) 0.86

Cobalt-Protoporphyrin Improves Heart Function by Blunting Oxidative Stress and Restoring NO Synthase Equilibrium in an Animal Model of Experimental Diabetes. Front Physiol (2012) 0.85

β₂-Adrenoceptors, NADPH oxidase, ROS and p38 MAPK: another 'radical' road to heart failure? Br J Pharmacol (2011) 0.85

Hydralazine and organic nitrates restore impaired excitation-contraction coupling by reducing calcium leak associated with nitroso-redox imbalance. J Biol Chem (2013) 0.85

Glutathione oxidation unmasks proarrhythmic vulnerability of chronically hyperglycemic guinea pigs. Am J Physiol Heart Circ Physiol (2013) 0.84

Effects of cardioselective KATP channel antagonism on basal, stimulated, and ischaemic myocardial function in in vivo failing canine heart. Br J Pharmacol (2002) 0.84

Nitroxyl (HNO): A novel approach for the acute treatment of heart failure. Circ Heart Fail (2013) 0.84

Novel regulation of cardiac force-frequency relation by CREM (cAMP response element modulator). FASEB J (2003) 0.84

CCR5 inhibition prevents cardiac dysfunction in the SIV/macaque model of HIV. J Am Heart Assoc (2014) 0.83

Synthesis and chemical and biological comparison of nitroxyl- and nitric oxide-releasing diazeniumdiolate-based aspirin derivatives. J Med Chem (2013) 0.83

Reversal of isoflurane-induced depression of myocardial contraction by nitroxyl via myofilament sensitization to Ca2+. J Pharmacol Exp Ther (2011) 0.83

Reverse remodeling and enhanced adrenergic reserve from passive external support in experimental dilated heart failure. J Am Coll Cardiol (2002) 0.82

Warburg effect's manifestation in aggressive pheochromocytomas and paragangliomas: insights from a mouse cell model applied to human tumor tissue. PLoS One (2012) 0.82

The shy Angeli and his elusive creature: the HNO route to vasodilation. Am J Physiol Heart Circ Physiol (2009) 0.81

The p75 neurotrophin receptor evades the endolysosomal route in neuronal cells, favouring multivesicular bodies specialised for exosomal release. J Cell Sci (2014) 0.80

Expression and localization of myosin-1d in the developing nervous system. Brain Res (2012) 0.80

Depletion of cellular glutathione modulates LIF-induced JAK1-STAT3 signaling in cardiac myocytes. Int J Biochem Cell Biol (2012) 0.80

Comparison of changes in body composition during puberty development of obese and normal-weight children in China. Biomed Environ Sci (2009) 0.79

Endocardial endothelium is a key determinant of force-frequency relationship in rat ventricular myocardium. J Appl Physiol (1985) (2013) 0.79

Neurotrophic factors. Preface. Handb Exp Pharmacol (2014) 0.78

When the heart sleeps... is the vagus resetting the myocardial 'redox clock'? Cardiovasc Res (2008) 0.77

Differential effects of pulsatile versus steady flow on coronary endothelial membrane potential. Am J Physiol Heart Circ Physiol (2003) 0.77

Forever young?: nerve growth factor, sympathetic fibers, and right ventricle pressure overload. Circ Res (2007) 0.77

Multi-responsive nitrobenzene-based amphiphilic random copolymer assemblies. Chem Commun (Camb) (2013) 0.77

[Effects of induced deletion of repeats in binding domain of the VLDL receptor on its ligand-binding capacity]. Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai) (2002) 0.77

Genes, geography and geometry: the "critical mass" in hypertrophic cardiomyopathy. J Mol Diagn (2008) 0.77

NRIF is a regulator of neuronal cholesterol biosynthesis genes. J Mol Neurosci (2008) 0.76