Published in Dis Model Mech on March 24, 2010
LncRNAs expression signatures of renal clear cell carcinoma revealed by microarray. PLoS One (2012) 1.59
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E2F7 and E2F8 promote angiogenesis through transcriptional activation of VEGFA in cooperation with HIF1. EMBO J (2012) 1.09
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The visual system of zebrafish and its use to model human ocular diseases. Dev Neurobiol (2012) 0.96
Blood flow suppresses vascular Notch signalling via dll4 and is required for angiogenesis in response to hypoxic signalling. Cardiovasc Res (2013) 0.94
Complex cellular functions of the von Hippel-Lindau tumor suppressor gene: insights from model organisms. Oncogene (2011) 0.92
Investigating the genetics of visual processing, function and behaviour in zebrafish. Neurogenetics (2011) 0.86
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Exploring the HIFs, buts and maybes of hypoxia signalling in disease: lessons from zebrafish models. Dis Model Mech (2015) 0.75
The zebrafish eye-a paradigm for investigating human ocular genetics. Eye (Lond) (2016) 0.75
Von Hippel-Lindau disease (VHL): a need for a murine model with retinal hemangioblastoma. Histol Histopathol (2012) 0.75
Deriving cell lines from zebrafish embryos and tumors. Zebrafish (2013) 0.75
Loss of vhl in the zebrafish pronephros recapitulates early stages of human clear cell renal cell carcinoma. Dis Model Mech (2016) 0.75
SENP1 promotes proliferation of clear cell renal cell carcinoma through activation of glycolysis. Oncotarget (2016) 0.75
Neuroprotective effects respond to cerebral ischemia without susceptibility to HB-tumorigenesis in VHL heterozygous knockout mice. Mol Carcinog (2017) 0.75
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Lgr5(+ve) stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro. Cell Stem Cell (2010) 7.25
Rapid chemotherapy-induced acute endothelial progenitor cell mobilization: implications for antiangiogenic drugs as chemosensitizing agents. Cancer Cell (2008) 4.51
Limitations and possibilities of small RNA digital gene expression profiling. Nat Methods (2009) 4.34
tp53 mutant zebrafish develop malignant peripheral nerve sheath tumors. Proc Natl Acad Sci U S A (2005) 4.15
Candidate exome capture identifies mutation of SDCCAG8 as the cause of a retinal-renal ciliopathy. Nat Genet (2010) 3.99
Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways. Cell (2011) 3.95
Shared and separate functions of polo-like kinases and aurora kinases in cancer. Nat Rev Cancer (2010) 3.74
Endothelial cells dynamically compete for the tip cell position during angiogenic sprouting. Nat Cell Biol (2010) 3.61
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High-dose chemotherapy with hematopoietic stem-cell rescue for high-risk breast cancer. N Engl J Med (2003) 3.15
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Human embryonic stem cell-derived cardiomyocytes survive and mature in the mouse heart and transiently improve function after myocardial infarction. Stem Cell Res (2007) 3.04
The immunoglobulin heavy-chain locus in zebrafish: identification and expression of a previously unknown isotype, immunoglobulin Z. Nat Immunol (2005) 2.90
The Wnt/beta-catenin pathway regulates cardiac valve formation. Nature (2003) 2.89
FAN1 mutations cause karyomegalic interstitial nephritis, linking chronic kidney failure to defective DNA damage repair. Nat Genet (2012) 2.74
Target-selected inactivation of the zebrafish rag1 gene. Science (2002) 2.60
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Exome capture reveals ZNF423 and CEP164 mutations, linking renal ciliopathies to DNA damage response signaling. Cell (2012) 2.54
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Ccbe1 is required for embryonic lymphangiogenesis and venous sprouting. Nat Genet (2009) 2.23
Fatigue and relating factors in high-risk breast cancer patients treated with adjuvant standard or high-dose chemotherapy: a longitudinal study. J Clin Oncol (2005) 2.14
Zebrafish mutants in the von Hippel-Lindau tumor suppressor display a hypoxic response and recapitulate key aspects of Chuvash polycythemia. Blood (2009) 2.11
Analysis of a zebrafish VEGF receptor mutant reveals specific disruption of angiogenesis. Curr Biol (2002) 2.06
The ets-domain transcription factor Spdef promotes maturation of goblet and paneth cells in the intestinal epithelium. Gastroenterology (2009) 2.01
MicroRNA-24 regulates vascularity after myocardial infarction. Circulation (2011) 1.98
NEK8 links the ATR-regulated replication stress response and S phase CDK activity to renal ciliopathies. Mol Cell (2013) 1.97
Redundant roles for sox7 and sox18 in arteriovenous specification in zebrafish. Circ Res (2007) 1.95
Mapping the consequence of Notch1 proteolysis in vivo with NIP-CRE. Development (2007) 1.94
Functional analyses of human and zebrafish 18-amino acid in-frame deletion pave the way for domain mapping of the cerebral cavernous malformation 3 protein. Hum Mutat (2009) 1.90
Bone regenerates via dedifferentiation of osteoblasts in the zebrafish fin. Dev Cell (2011) 1.86
The leukemia-associated Mllt10/Af10-Dot1l are Tcf4/β-catenin coactivators essential for intestinal homeostasis. PLoS Biol (2010) 1.81
Development of the zebrafish lymphatic system requires VEGFC signaling. Curr Biol (2006) 1.78
Meta-analysis of genome-wide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22. Ann Rheum Dis (2010) 1.75
Early endocardial morphogenesis requires Scl/Tal1. PLoS Genet (2007) 1.73
Primary colorectal cancers and their subsequent hepatic metastases are genetically different: implications for selection of patients for targeted treatment. Clin Cancer Res (2011) 1.64
Mesenchymal stem cells induce resistance to chemotherapy through the release of platinum-induced fatty acids. Cancer Cell (2011) 1.62
Endothelial cell-specific FGD5 involvement in vascular pruning defines neovessel fate in mice. Circulation (2012) 1.60
The molecular basis of class side effects due to treatment with inhibitors of the VEGF/VEGFR pathway. Curr Clin Pharmacol (2008) 1.60
Mutations in CCBE1 cause generalized lymph vessel dysplasia in humans. Nat Genet (2009) 1.59
Target practice: lessons from phase III trials with bevacizumab and vatalanib in the treatment of advanced colorectal cancer. Oncologist (2007) 1.58
A novel multistep mechanism for initial lymphangiogenesis in mouse embryos based on ultramicroscopy. EMBO J (2013) 1.58
Arteries provide essential guidance cues for lymphatic endothelial cells in the zebrafish trunk. Development (2010) 1.57
DNA replication stress underlies renal phenotypes in CEP290-associated Joubert syndrome. J Clin Invest (2015) 1.55
Genetic analysis of von Hippel-Lindau disease. Hum Mutat (2010) 1.55
Gain-of-function mutations of PPM1D/Wip1 impair the p53-dependent G1 checkpoint. J Cell Biol (2013) 1.52
Vegfc/Flt4 signalling is suppressed by Dll4 in developing zebrafish intersegmental arteries. Development (2009) 1.51
Retinoic acid signalling in the zebrafish embryo is necessary during pre-segmentation stages to pattern the anterior-posterior axis of the CNS and to induce a pectoral fin bud. Development (2002) 1.50
ccm1 cell autonomously regulates endothelial cellular morphogenesis and vascular tubulogenesis in zebrafish. Hum Mol Genet (2008) 1.47
Zebrafish VEGF receptors: a guideline to nomenclature. PLoS Genet (2008) 1.46
Zebrafish development and regeneration: new tools for biomedical research. Int J Dev Biol (2009) 1.46
Flt1 acts as a negative regulator of tip cell formation and branching morphogenesis in the zebrafish embryo. Development (2011) 1.44
Two populations of endochondral osteoblasts with differential sensitivity to Hedgehog signalling. Development (2009) 1.42
Retinoic acid and Cyp26b1 are critical regulators of osteogenesis in the axial skeleton. Development (2008) 1.42
Validation of serum amyloid α as an independent biomarker for progression-free and overall survival in metastatic renal cell cancer patients. Eur Urol (2012) 1.41
CCBE1 is essential for mammalian lymphatic vascular development and enhances the lymphangiogenic effect of vascular endothelial growth factor-C in vivo. Circ Res (2011) 1.39
LRRC50, a conserved ciliary protein implicated in polycystic kidney disease. J Am Soc Nephrol (2008) 1.38
Ischemia/reperfusion accelerates the outgrowth of hepatic micrometastases in a highly standardized murine model. Hepatology (2005) 1.37
A versatile toolkit to produce sensitive FRET biosensors to visualize signaling in time and space. Sci Signal (2013) 1.37
Human embryonic mesenchymal stem cell-derived conditioned medium rescues kidney function in rats with established chronic kidney disease. PLoS One (2012) 1.36
Stimulation of angiogenesis by Ras proteins. Biochim Biophys Acta (2004) 1.35
Role of delta-like-4/Notch in the formation and wiring of the lymphatic network in zebrafish. Arterioscler Thromb Vasc Biol (2010) 1.35
A critical role for the Wnt effector Tcf4 in adult intestinal homeostatic self-renewal. Mol Cell Biol (2012) 1.34
Patient selection for oncology phase I trials: a multi-institutional study of prognostic factors. J Clin Oncol (2012) 1.33
The SYSCILIA gold standard (SCGSv1) of known ciliary components and its applications within a systems biology consortium. Cilia (2013) 1.31
Chemotherapy enhances metastasis formation via VEGFR-1-expressing endothelial cells. Cancer Res (2011) 1.31
Functional aspects of primary cilia in signaling, cell cycle and tumorigenesis. Cilia (2013) 1.28
Platelets take up the monoclonal antibody bevacizumab. Clin Cancer Res (2007) 1.28
Rapid BAC selection for tol2-mediated transgenesis in zebrafish. Development (2011) 1.27
T-cell factor 4 (Tcf7l2) maintains proliferative compartments in zebrafish intestine. EMBO Rep (2007) 1.26
Lithium causes G2 arrest of renal principal cells. J Am Soc Nephrol (2014) 1.26
A phase I, randomized, open-label, parallel-cohort, dose-finding study of elacridar (GF120918) and oral topotecan in cancer patients. Clin Cancer Res (2007) 1.24
Accelerated perinecrotic outgrowth of colorectal liver metastases following radiofrequency ablation is a hypoxia-driven phenomenon. Ann Surg (2009) 1.24
Control of colorectal metastasis formation by K-Ras. Biochim Biophys Acta (2005) 1.22
Liver regeneration is an angiogenesis- associated phenomenon. Ann Surg (2002) 1.21
Contribution of granulocyte colony-stimulating factor to the acute mobilization of endothelial precursor cells by vascular disrupting agents. Cancer Res (2009) 1.20
Rotation and asymmetric development of the zebrafish heart requires directed migration of cardiac progenitor cells. Dev Cell (2008) 1.20
Progenitor marker CD133 mRNA is elevated in peripheral blood of cancer patients with bone metastases. Clin Cancer Res (2006) 1.16
Genomic and transcriptomic plasticity in treatment-naive ovarian cancer. Genome Res (2013) 1.15
miR-31 functions as a negative regulator of lymphatic vascular lineage-specific differentiation in vitro and vascular development in vivo. Mol Cell Biol (2010) 1.15
Cytosolic p120-catenin regulates growth of metastatic lobular carcinoma through Rock1-mediated anoikis resistance. J Clin Invest (2011) 1.13
Glycation induces formation of amyloid cross-beta structure in albumin. J Biol Chem (2003) 1.12
A phase I pharmacologic study of necitumumab (IMC-11F8), a fully human IgG1 monoclonal antibody directed against EGFR in patients with advanced solid malignancies. Clin Cancer Res (2010) 1.12