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1
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Widespread amyloid deposition in transplanted human pancreatic islets.
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N Engl J Med
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2008
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2.13
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2
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Pancreatic biopsy by minimal tail resection in live adult patients at the onset of type 1 diabetes: experiences from the DiViD study.
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Diabetologia
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2014
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2.04
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3
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Utilization of small pediatric donors including infants for pancreas and kidney transplantation: exemplification of the surgical technique and the surveillance.
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Ann Surg
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2014
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2.01
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4
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Tissue factor produced by the endocrine cells of the islets of Langerhans is associated with a negative outcome of clinical islet transplantation.
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Diabetes
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2005
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1.96
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5
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A systems genetics approach identifies genes and pathways for type 2 diabetes in human islets.
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Cell Metab
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2012
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1.93
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6
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Identification of proliferative and mature β-cells in the islets of Langerhans.
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Nature
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2016
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1.71
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7
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Refinement of the automated method for human islet isolation and presentation of a closed system for in vitro islet culture.
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Transplantation
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2004
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1.64
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8
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Current advances and travails in islet transplantation.
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Diabetes
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2009
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1.63
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9
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Inhibition of thrombin abrogates the instant blood-mediated inflammatory reaction triggered by isolated human islets: possible application of the thrombin inhibitor melagatran in clinical islet transplantation.
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Diabetes
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2002
|
1.52
|
|
10
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Standardized experimental brain death model for studies of intracranial dynamics, organ preservation, and organ transplantation in the pig.
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Crit Care Med
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2011
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1.52
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11
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Enteroviruses and the pathogenesis of type 1 diabetes revisited: cross-reactivity of enterovirus capsid protein (VP1) antibodies with human mitochondrial proteins.
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J Pathol
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2013
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1.51
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12
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Characterization of endocrine progenitor cells and critical factors for their differentiation in human adult pancreatic cell culture.
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Diabetes
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2003
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1.48
|
|
13
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Interferons induce an antiviral state in human pancreatic islet cells.
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Virology
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2007
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1.41
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14
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[Swedish medical research does not need more control].
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Lakartidningen
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2014
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1.39
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15
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Are therapeutic human mesenchymal stromal cells compatible with human blood?
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Stem Cells
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2012
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1.36
|
|
16
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Inflammatory mediators expressed in human islets of Langerhans: implications for islet transplantation.
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Biochem Biophys Res Commun
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2003
|
1.33
|
|
17
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Can cells and biomaterials in therapeutic medicine be shielded from innate immune recognition?
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Trends Immunol
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2010
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1.28
|
|
18
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Formation of composite endothelial cell-mesenchymal stem cell islets: a novel approach to promote islet revascularization.
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Diabetes
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2008
|
1.26
|
|
19
|
Islet surface heparinization prevents the instant blood-mediated inflammatory reaction in islet transplantation.
|
Diabetes
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2007
|
1.24
|
|
20
|
Clinical and experimental pancreatic islet transplantation to striated muscle: establishment of a vascular system similar to that in native islets.
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Diabetes
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2010
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1.20
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21
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Detection of metastatic insulinoma by positron emission tomography with [(68)ga]exendin-4-a case report.
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J Clin Endocrinol Metab
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2014
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1.15
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22
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Dissecting the instant blood-mediated inflammatory reaction in islet xenotransplantation.
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Xenotransplantation
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2008
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1.12
|
|
23
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In vivo imaging of the glucagonlike peptide 1 receptor in the pancreas with 68Ga-labeled DO3A-exendin-4.
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J Nucl Med
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2013
|
1.12
|
|
24
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Control of instant blood-mediated inflammatory reaction to improve islets of Langerhans engraftment.
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Curr Opin Organ Transplant
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2011
|
1.10
|
|
25
|
Insulin-heparin infusions peritransplant substantially improve single-donor clinical islet transplant success.
|
Transplantation
|
2010
|
1.10
|
|
26
|
Detection of enterovirus in the islet cells of patients with type 1 diabetes: what do we learn from immunohistochemistry?
|
Diabetologia
|
2013
|
1.09
|
|
27
|
Positron emission tomography: a real-time tool to quantify early islet engraftment in a preclinical large animal model.
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Transplantation
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2007
|
1.05
|
|
28
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The importance of tryptic-like activity in purified enzyme blends for efficient islet isolation.
|
Transplantation
|
2009
|
1.04
|
|
29
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Revisiting the notion of type 1 diabetes being a T-cell-mediated autoimmune disease.
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Curr Opin Endocrinol Diabetes Obes
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2013
|
1.02
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|
30
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Large-scale bioreactor expansion of tumor-infiltrating lymphocytes.
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J Immunol Methods
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2010
|
1.02
|
|
31
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Glucocorticoids reduce pro-inflammatory cytokines and tissue factor in vitro and improve function of transplanted human islets in vivo.
|
Transpl Int
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2008
|
1.01
|
|
32
|
Low molecular weight dextran sulfate prevents the instant blood-mediated inflammatory reaction induced by adult porcine islets.
|
Transplantation
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2004
|
1.01
|
|
33
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In vivo and in vitro characterization of [18F]-FE-(+)-DTBZ as a tracer for beta-cell mass.
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Nucl Med Biol
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2010
|
1.01
|
|
34
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Proliferation and plasticity of human beta cells on physiologically occurring laminin isoforms.
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Mol Cell Endocrinol
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2012
|
1.00
|
|
35
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Acute antibody-mediated complement activation mediates lysis of pancreatic islets cells and may cause tissue loss in clinical islet transplantation.
|
Transplantation
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2008
|
1.00
|
|
36
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The instant blood-mediated inflammatory reaction characterized in hepatocyte transplantation.
|
Transplantation
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2011
|
0.99
|
|
37
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No beneficial effect of two-layer storage compared with UW-storage on human islet isolation and transplantation.
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Transplantation
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2007
|
0.98
|
|
38
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Antiviral effect of nicotinamide on enterovirus-infected human islets in vitro: effect on virus replication and chemokine secretion.
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J Med Virol
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2009
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0.98
|
|
39
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Quantitative imaging of serotonergic biosynthesis and degradation in the endocrine pancreas.
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J Nucl Med
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2014
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0.97
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40
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Adenovirus CD40 ligand gene therapy counteracts immune escape mechanisms in the tumor Microenvironment.
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J Immunol
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2004
|
0.97
|
|
41
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Composite islet-endothelial cell grafts: a novel approach to counteract innate immunity in islet transplantation.
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Am J Transplant
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2005
|
0.96
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|
42
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On the etiology of type 1 diabetes: a new animal model signifying a decisive role for bacteria eliciting an adverse innate immunity response.
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Am J Pathol
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2012
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0.95
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43
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Treatment efficacy and immune stimulation by AdCD40L gene therapy of spontaneous canine malignant melanoma.
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J Immunother
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2013
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0.95
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|
44
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Novel pancreatic beta cell-specific proteins: antibody-based proteomics for identification of new biomarker candidates.
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J Proteomics
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2012
|
0.93
|
|
45
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Preparatory studies of composite mesenchymal stem cell islets for application in intraportal islet transplantation.
|
Ups J Med Sci
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2010
|
0.93
|
|
46
|
Nicotinamide inhibits tissue factor expression in isolated human pancreatic islets: implications for clinical islet transplantation.
|
Transplantation
|
2003
|
0.93
|
|
47
|
Inflammatory gene expression in Coxsackievirus B-4-infected human islets of Langerhans.
|
Biochem Biophys Res Commun
|
2005
|
0.92
|
|
48
|
Induction of an antiviral state and attenuated coxsackievirus replication in type III interferon-treated primary human pancreatic islets.
|
J Virol
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2013
|
0.91
|
|
49
|
Intraportal pig islet xenotransplantation into athymic mice as an in vivo model for the study of the instant blood-mediated inflammatory reaction.
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Xenotransplantation
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2004
|
0.89
|
|
50
|
Efficient adenovector CD40 ligand immunotherapy of canine malignant melanoma.
|
J Immunother
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2008
|
0.89
|
|
51
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Sustained reversal of diabetes following islet transplantation to striated musculature in the rat.
|
J Surg Res
|
2008
|
0.89
|
|
52
|
Quantification of the islet product: presentation of a standardized current good manufacturing practices compliant system with minimal variability.
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Transplantation
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2011
|
0.88
|
|
53
|
Effects on isolated human pancreatic islet cells after infection with strains of enterovirus isolated at clinical presentation of type 1 diabetes.
|
Virus Res
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2006
|
0.88
|
|
54
|
Long-term engraftment and function of transplanted pancreatic islets in vascularized segments of small intestine.
|
Transpl Int
|
2010
|
0.87
|
|
55
|
Vitacyte collagenase HA: a novel enzyme blend for efficient human islet isolation.
|
Transplantation
|
2009
|
0.87
|
|
56
|
Positron emission tomography imaging of the glucagon-like peptide-1 receptor in healthy and streptozotocin-induced diabetic pigs.
|
Eur J Nucl Med Mol Imaging
|
2014
|
0.87
|
|
57
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The ratio between collagenase class I and class II influences the efficient islet release from the rat pancreas.
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Transplantation
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2008
|
0.86
|
|
58
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Modulation of innate immunity in human pancreatic islets infected with enterovirus in vitro.
|
J Med Virol
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2011
|
0.86
|
|
59
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T cell control of primary and latent cytomegalovirus infections in healthy subjects.
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J Clin Immunol
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2005
|
0.86
|
|
60
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Pathogen inactivation of human serum facilitates its clinical use for islet cell culture and subsequent transplantation.
|
Cell Transplant
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2010
|
0.86
|
|
61
|
Adenovirus serotype 5 vectors with Tat-PTD modified hexon and serotype 35 fiber show greatly enhanced transduction capacity of primary cell cultures.
|
PLoS One
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2013
|
0.86
|
|
62
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Isolation, expansion and functional assessment of CD4+CD25+FoxP3+ regulatory T cells and Tr1 cells from uremic patients awaiting kidney transplantation.
|
Transpl Immunol
|
2011
|
0.85
|
|
63
|
Further evidence for amyloid deposition in clinical pancreatic islet grafts.
|
Transplantation
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2012
|
0.85
|
|
64
|
Using HTK for prolonged pancreas preservation prior to human islet isolation.
|
J Surg Res
|
2011
|
0.85
|
|
65
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Antiviral treatment of Coxsackie B virus infection in human pancreatic islets.
|
Antiviral Res
|
2006
|
0.84
|
|
66
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Immunosuppressive drugs in islet xenotransplantation: a tool for gaining further insights in the mechanisms of the rejection process.
|
Transplantation
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2002
|
0.84
|
|
67
|
Anchoring of vascular endothelial growth factor to surface-immobilized heparin on pancreatic islets: implications for stimulating islet angiogenesis.
|
Tissue Eng Part A
|
2010
|
0.84
|
|
68
|
Low molecular weight dextran sulfate as complement inhibitor and cytoprotectant in solid organ and islet transplantation.
|
Mol Immunol
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2008
|
0.83
|
|
69
|
A vast amount of enzyme activity fails to be absorbed within the human pancreas: implications for cost-effective islet isolation procedures.
|
Transplantation
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2013
|
0.83
|
|
70
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CMV-specific T-cell immunity, viral load, and clinical outcome in seropositive renal transplant recipients: a pilot study.
|
Clin Transplant
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2009
|
0.83
|
|
71
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A new murine model of islet xenograft rejection: graft destruction is dependent on a major histocompatibility-specific interaction between T-cells and macrophages.
|
Diabetes
|
2003
|
0.83
|
|
72
|
The effect of truncated collagenase class I isomers on human islet isolation outcome.
|
Transplantation
|
2010
|
0.83
|
|
73
|
Antibody-based proteomics for discovery and exploration of proteins expressed in pancreatic islets.
|
Discov Med
|
2010
|
0.82
|
|
74
|
Decreased defluorination using the novel beta-cell imaging agent [18F]FE-DTBZ-d4 in pigs examined by PET.
|
EJNMMI Res
|
2011
|
0.82
|
|
75
|
Low molecular weight dextran sulfate is well tolerated in humans and increases endogenous expression of islet protective hepatocyte growth factor.
|
Transplantation
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2008
|
0.82
|
|
76
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Executive Summary of IPITA-TTS Opinion Leaders Report on the Future of β-Cell Replacement.
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Transplantation
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2016
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0.82
|
|
77
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Expression of human leukocyte antigen class I in endocrine and exocrine pancreatic tissue at onset of type 1 diabetes.
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Am J Pathol
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2015
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0.82
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78
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Infection of human islets of Langerhans with two strains of Coxsackie B virus serotype 1: assessment of virus replication, degree of cell death and induction of genes involved in the innate immunity pathway.
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J Med Virol
|
2013
|
0.82
|
|
79
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A new oxygen carrier for improved long-term storage of human pancreata before islet isolation.
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Transplantation
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2010
|
0.81
|
|
80
|
MyD88-dependent toll-like receptor signalling is not a requirement for fetal islet xenograft rejection in mice.
|
Xenotransplantation
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2004
|
0.80
|
|
81
|
Islet engraftment and revascularization in clinical and experimental transplantation.
|
Cell Transplant
|
2012
|
0.80
|
|
82
|
A new method for incorporating functional heparin onto the surface of islets of Langerhans.
|
Tissue Eng Part C Methods
|
2008
|
0.80
|
|
83
|
Mammalian tissue-free liberase: a new GMP-graded enzyme blend for human islet isolation.
|
Transplantation
|
2010
|
0.80
|
|
84
|
Pig islet xenotransplantation: activation of porcine endogenous retrovirus in the immediate post-transplantation period.
|
Xenotransplantation
|
2005
|
0.80
|
|
85
|
Intracerebral cytokine profiles in adult rats grafted with neural tissue of different immunological disparity.
|
Brain Res Bull
|
2004
|
0.80
|
|
86
|
Intragraft cytokine mRNA expression in rejecting and non-rejecting vascularized xenografts.
|
Xenotransplantation
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2003
|
0.79
|
|
87
|
Decreased proportion of cytomegalovirus specific CD8 T-cells but no signs of general immunosenescence in Alzheimer's disease.
|
PLoS One
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2013
|
0.79
|
|
88
|
Report from IPITA-TTS Opinion Leaders Meeting on the Future of β-Cell Replacement.
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Transplantation
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2016
|
0.79
|
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89
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Anakinra and tocilizumab enhance survival and function of human islets during culture: implications for clinical islet transplantation.
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Cell Transplant
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2013
|
0.78
|
|
90
|
Human islet distribution programme for basic research: activity over the last 5 years.
|
Diabetologia
|
2015
|
0.78
|
|
91
|
Human pancreatic islet preparations release HMGB1: (ir)relevance for graft engraftment.
|
Cell Transplant
|
2012
|
0.78
|
|
92
|
Adenovirus-mediated expression of the anticoagulant hirudin in human islets: a tool to make the islets biocompatible to blood.
|
Cell Transplant
|
2006
|
0.78
|
|
93
|
Maturation of in vitro-generated human islets after transplantation in nude mice.
|
Mol Cell Endocrinol
|
2006
|
0.78
|
|
94
|
Human islet isolation processing times shortened by one hour: minimized incubation time between tissue harvest and islet purification.
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Transplantation
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2013
|
0.78
|
|
95
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A distinct Th1 immune response precedes the described Th2 response in islet xenograft rejection.
|
Diabetes
|
2002
|
0.78
|
|
96
|
Immunological shielding by induced recruitment of regulatory T-lymphocytes delays rejection of islets transplanted in muscle.
|
Cell Transplant
|
2014
|
0.78
|
|
97
|
Oxygen-charged HTK-F6H8 emulsion reduces ischemia-reperfusion injury in kidneys from brain-dead pigs.
|
J Surg Res
|
2012
|
0.77
|
|
98
|
Preclinical evaluation of a 68Ga-labeled biotin analogue for applications in islet transplantation.
|
Nucl Med Biol
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2011
|
0.77
|
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99
|
Transplanted functional islet mass: donor, islet preparation, and recipient factors influence early graft function in islet-after-kidney patients.
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Transplantation
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2012
|
0.77
|
|
100
|
Gene expression analysis of human islets in a subject at onset of type 1 diabetes.
|
Acta Diabetol
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2013
|
0.77
|
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101
|
Mesenchymal stromal cells to halt the progression of type 1 diabetes?
|
Curr Diab Rep
|
2015
|
0.77
|
|
102
|
Co-stimulatory molecules in islet xenotransplantation: CTLA4Ig treatment in CD40 ligand-deficient mice.
|
Cell Transplant
|
2002
|
0.77
|
|
103
|
Quantification of lymphocytes propagating from rat-kidney allografts--a tool to monitor anti-rejection treatment.
|
Transpl Immunol
|
2002
|
0.76
|
|
104
|
Possible transmission of zoonoses in xenotransplantation: porcine endogenous retroviruses (PERVs) from an immunological point of view.
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Acta Vet Scand Suppl
|
2004
|
0.76
|
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105
|
Distribution of adoptively transferred porcine T-lymphoblasts tracked by (18)F-2-fluoro-2-deoxy-D-glucose and position emission tomography.
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Nucl Med Biol
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2011
|
0.76
|
|
106
|
Lymphocyte propagation from biopsies of kidney allografts.
|
Transpl Immunol
|
2006
|
0.76
|
|
107
|
Adenovirus-mediated expression of human CD55 or CD59 protects adult porcine islets from complement-mediated cell lysis by human serum.
|
Transplantation
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2003
|
0.76
|
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108
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A novel model for studies of blood-mediated long-term responses to cellular transplants.
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Ups J Med Sci
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2014
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0.75
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109
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Insulin independence after conversion from tacrolimus to cyclosporine in islet transplantation.
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Transpl Int
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2012
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0.75
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110
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Islet Transplantation & β-Cell Replacement Therapies for Diabetes.
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J Transplant
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2012
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0.75
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111
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Syngeneic islet transplantations into the submandibular gland of mice.
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Transplantation
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2011
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0.75
|
|
112
|
Imaging the in vivo fate of human T cells following transplantation in immunoincompetent mice - implications for clinical cell therapy trials.
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Transpl Immunol
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2013
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0.75
|
|
113
|
Glucose Effectiveness: The Mouse Trap in the Development of Novel ß-Cell Replacement Therapies.
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Transplantation
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2016
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0.75
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114
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The efficacy of CD40 ligand blockade in discordant pig-to-rat islet xenotransplantation is correlated with an immunosuppressive effect of immunoglobulin.
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Transplantation
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2005
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0.75
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115
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The recent finding that tissue factor is produced by the pancreatic islets constitutes a possible link between insulin resistance and cardiovascular disease.
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Am J Ther
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2005
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0.75
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116
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[Replacement therapy with beta-cells: the way to treat diabetes in the future?].
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Duodecim
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2004
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0.75
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117
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Tribute to Carl-Gustav Groth (1933-2014), first president of the International Xenotransplantation Association.
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Xenotransplantation
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2014
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0.75
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118
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Erratum. National Institutes of Health-Sponsored Clinical Islet Transplantation Consortium Phase 3 Trial: Manufacture of a Complex Cellular Product at Eight Processing Facilities. Diabetes 2016;65:3418-3428.
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Diabetes
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2017
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0.75
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119
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Perfluorohexyloctane improves long-term storage of rat pancreata for subsequent islet isolation.
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Transpl Int
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2009
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0.75
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120
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In Vivo Effects of Mesenchymal Stromal Cells in Two Patients With Severe Acute Respiratory Distress Syndrome.
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Stem Cells Transl Med
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2016
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0.75
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121
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Effect of plasma exchange in combination with deoxyspergualin on the survival of guinea-pig hearts in macrophage-depleted C6-deficient rats.
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Xenotransplantation
|
2003
|
0.75
|
|
122
|
Evaluation of Perfluorohexyloctane/Polydimethylsiloxane for Pancreas Preservation for Clinical Islet Isolation and Transplantation.
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Cell Transplant
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2016
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0.75
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123
|
Erratum. Direct Substrate Delivery Into Mitochondrial Fission-Deficient Pancreatic Islets Rescues Insulin Secretion. Diabetes 2017;66:1247-1257.
|
Diabetes
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2017
|
0.75
|
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124
|
Characterization of Innate Immunity in an Extended Whole Blood Model of Human Islet Allotransplantation.
|
Cell Transplant
|
2015
|
0.75
|