1
|
Obesity-induced hypertension: role of sympathetic nervous system, leptin, and melanocortins.
|
J Biol Chem
|
2010
|
2.53
|
2
|
Melanocortin-4 receptor mediates chronic cardiovascular and metabolic actions of leptin.
|
Hypertension
|
2006
|
1.80
|
3
|
Melanocortin-4 receptor-deficient mice are not hypertensive or salt-sensitive despite obesity, hyperinsulinemia, and hyperleptinemia.
|
Hypertension
|
2005
|
1.72
|
4
|
Inhibitor κB kinase 2 is a myosin light chain kinase in vascular smooth muscle.
|
Circ Res
|
2013
|
1.42
|
5
|
Control of blood pressure, appetite, and glucose by leptin in mice lacking leptin receptors in proopiomelanocortin neurons.
|
Hypertension
|
2011
|
1.30
|
6
|
Role of adrenergic activity in pressor responses to chronic melanocortin receptor activation.
|
Hypertension
|
2004
|
1.29
|
7
|
Hypertension: physiology and pathophysiology.
|
Compr Physiol
|
2012
|
1.18
|
8
|
Obesity-associated hypertension and kidney disease.
|
Curr Opin Nephrol Hypertens
|
2003
|
1.18
|
9
|
Aldosterone antagonism attenuates obesity-induced hypertension and glomerular hyperfiltration.
|
Hypertension
|
2003
|
1.14
|
10
|
Impact of obesity on renal structure and function in the presence and absence of hypertension: evidence from melanocortin-4 receptor-deficient mice.
|
Am J Physiol Regul Integr Comp Physiol
|
2009
|
1.13
|
11
|
Chronic central leptin infusion restores cardiac sympathetic-vagal balance and baroreflex sensitivity in diabetic rats.
|
Am J Physiol Heart Circ Physiol
|
2008
|
1.04
|
12
|
Differential control of metabolic and cardiovascular functions by melanocortin-4 receptors in proopiomelanocortin neurons.
|
Am J Physiol Regul Integr Comp Physiol
|
2013
|
0.97
|
13
|
Chronic central ghrelin infusion reduces blood pressure and heart rate despite increasing appetite and promoting weight gain in normotensive and hypertensive rats.
|
Peptides
|
2013
|
0.94
|
14
|
Activation of the central melanocortin system contributes to the increased arterial pressure in obese Zucker rats.
|
Am J Physiol Regul Integr Comp Physiol
|
2011
|
0.93
|
15
|
Enhanced blood pressure and appetite responses to chronic central melanocortin-3/4 receptor blockade in dietary-induced obesity.
|
J Hypertens
|
2010
|
0.91
|
16
|
Role of proopiomelanocortin neuron Stat3 in regulating arterial pressure and mediating the chronic effects of leptin.
|
Hypertension
|
2013
|
0.91
|
17
|
Control of metabolic and cardiovascular function by the leptin-brain melanocortin pathway.
|
IUBMB Life
|
2013
|
0.90
|
18
|
Cardiovascular, renal, and metabolic responses to chronic central administration of agouti-related peptide.
|
Hypertension
|
2004
|
0.89
|
19
|
Systemic but not central nervous system nitric oxide synthase inhibition exacerbates the hypertensive effects of chronic melanocortin-3/4 receptor activation.
|
Hypertension
|
2011
|
0.87
|
20
|
Central leptin replacement enhances chemorespiratory responses in leptin-deficient mice independent of changes in body weight.
|
Pflugers Arch
|
2012
|
0.86
|
21
|
Perinatal salt restriction: a new pathway to programming insulin resistance and dyslipidemia in adult wistar rats.
|
Pediatr Res
|
2004
|
0.84
|
22
|
Chronic effects of centrally administered adiponectin on appetite, metabolism and blood pressure regulation in normotensive and hypertensive rats.
|
Peptides
|
2012
|
0.84
|
23
|
Chronic blood pressure and appetite responses to central leptin infusion in rats fed a high fat diet.
|
J Hypertens
|
2011
|
0.82
|
24
|
Chronic central nervous system hyperinsulinemia and regulation of arterial pressure and food intake.
|
J Hypertens
|
2006
|
0.77
|
25
|
Maternal high-sodium intake alters the responsiveness of the renin-angiotensin system in adult offspring.
|
Life Sci
|
2012
|
0.76
|
26
|
Role of hindbrain melanocortin-4 receptor activity in controlling cardiovascular and metabolic functions in spontaneously hypertensive rats.
|
J Hypertens
|
2015
|
0.75
|