Alexandre A da Silva

Author PubWeight™ 28.33‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Obesity-induced hypertension: role of sympathetic nervous system, leptin, and melanocortins. J Biol Chem 2010 2.53
2 Melanocortin-4 receptor mediates chronic cardiovascular and metabolic actions of leptin. Hypertension 2006 1.80
3 Melanocortin-4 receptor-deficient mice are not hypertensive or salt-sensitive despite obesity, hyperinsulinemia, and hyperleptinemia. Hypertension 2005 1.72
4 Inhibitor κB kinase 2 is a myosin light chain kinase in vascular smooth muscle. Circ Res 2013 1.42
5 Control of blood pressure, appetite, and glucose by leptin in mice lacking leptin receptors in proopiomelanocortin neurons. Hypertension 2011 1.30
6 Role of adrenergic activity in pressor responses to chronic melanocortin receptor activation. Hypertension 2004 1.29
7 Hypertension: physiology and pathophysiology. Compr Physiol 2012 1.18
8 Obesity-associated hypertension and kidney disease. Curr Opin Nephrol Hypertens 2003 1.18
9 Aldosterone antagonism attenuates obesity-induced hypertension and glomerular hyperfiltration. Hypertension 2003 1.14
10 Impact of obesity on renal structure and function in the presence and absence of hypertension: evidence from melanocortin-4 receptor-deficient mice. Am J Physiol Regul Integr Comp Physiol 2009 1.13
11 Chronic central leptin infusion restores cardiac sympathetic-vagal balance and baroreflex sensitivity in diabetic rats. Am J Physiol Heart Circ Physiol 2008 1.04
12 Differential control of metabolic and cardiovascular functions by melanocortin-4 receptors in proopiomelanocortin neurons. Am J Physiol Regul Integr Comp Physiol 2013 0.97
13 Chronic central ghrelin infusion reduces blood pressure and heart rate despite increasing appetite and promoting weight gain in normotensive and hypertensive rats. Peptides 2013 0.94
14 Activation of the central melanocortin system contributes to the increased arterial pressure in obese Zucker rats. Am J Physiol Regul Integr Comp Physiol 2011 0.93
15 Enhanced blood pressure and appetite responses to chronic central melanocortin-3/4 receptor blockade in dietary-induced obesity. J Hypertens 2010 0.91
16 Role of proopiomelanocortin neuron Stat3 in regulating arterial pressure and mediating the chronic effects of leptin. Hypertension 2013 0.91
17 Control of metabolic and cardiovascular function by the leptin-brain melanocortin pathway. IUBMB Life 2013 0.90
18 Cardiovascular, renal, and metabolic responses to chronic central administration of agouti-related peptide. Hypertension 2004 0.89
19 Systemic but not central nervous system nitric oxide synthase inhibition exacerbates the hypertensive effects of chronic melanocortin-3/4 receptor activation. Hypertension 2011 0.87
20 Central leptin replacement enhances chemorespiratory responses in leptin-deficient mice independent of changes in body weight. Pflugers Arch 2012 0.86
21 Perinatal salt restriction: a new pathway to programming insulin resistance and dyslipidemia in adult wistar rats. Pediatr Res 2004 0.84
22 Chronic effects of centrally administered adiponectin on appetite, metabolism and blood pressure regulation in normotensive and hypertensive rats. Peptides 2012 0.84
23 Chronic blood pressure and appetite responses to central leptin infusion in rats fed a high fat diet. J Hypertens 2011 0.82
24 Chronic central nervous system hyperinsulinemia and regulation of arterial pressure and food intake. J Hypertens 2006 0.77
25 Maternal high-sodium intake alters the responsiveness of the renin-angiotensin system in adult offspring. Life Sci 2012 0.76
26 Role of hindbrain melanocortin-4 receptor activity in controlling cardiovascular and metabolic functions in spontaneously hypertensive rats. J Hypertens 2015 0.75