Published in J Biol Chem on March 30, 2010
Non-canonical NF-κB signaling pathway. Cell Res (2010) 3.03
Modulation of NF-κB signalling by microbial pathogens. Nat Rev Microbiol (2011) 1.64
NF-κB inducing kinase: a key regulator in the immune system and in cancer. Cytokine Growth Factor Rev (2010) 1.28
NF-κB and cancer: a paradigm of Yin-Yang. Am J Cancer Res (2010) 1.08
The cytoplasmic domain of the HIV-1 glycoprotein gp41 induces NF-κB activation through TGF-β-activated kinase 1. Cell Host Microbe (2012) 1.06
Roles for TNF-receptor associated factor 3 (TRAF3) in lymphocyte functions. Cytokine Growth Factor Rev (2013) 0.88
Activation of NF-κB by the Kaposi's sarcoma-associated herpesvirus K15 protein involves recruitment of the NF-κB-inducing kinase, IκB kinases, and phosphorylation of p65. J Virol (2014) 0.82
Actin-dependent activation of serum response factor in T cells by the viral oncoprotein tip. Cell Commun Signal (2012) 0.80
TNF-α Modulation of Intestinal Tight Junction Permeability Is Mediated by NIK/IKK-α Axis Activation of the Canonical NF-κB Pathway. Am J Pathol (2016) 0.78
The tumor marker Fascin is induced by the Epstein-Barr virus-encoded oncoprotein LMP1 via NF-κB in lymphocytes and contributes to their invasive migration. Cell Commun Signal (2014) 0.78
NF-κB Signaling Pathway in Controlling Intervertebral Disk Cell Response to Inflammatory and Mechanical Stressors. Phys Ther (2016) 0.77
Activators and target genes of Rel/NF-kappaB transcription factors. Oncogene (1999) 13.46
Regulation and function of NF-kappaB transcription factors in the immune system. Annu Rev Immunol (2009) 11.76
Promiscuous mutations activate the noncanonical NF-kappaB pathway in multiple myeloma. Cancer Cell (2007) 7.24
Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma. Cancer Cell (2007) 7.10
Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation [corrected]. Nat Cell Biol (2006) 6.11
Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-kappaB signaling. Nat Immunol (2008) 4.33
Transcriptional regulation via the NF-kappaB signaling module. Oncogene (2006) 3.92
Noncanonical NF-kappaB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK. Nat Immunol (2008) 3.91
Regulation of tissue homeostasis by NF-kappaB signalling: implications for inflammatory diseases. Nat Rev Immunol (2009) 3.51
A fourth IkappaB protein within the NF-kappaB signaling module. Cell (2007) 3.34
Activation of IKKalpha target genes depends on recognition of specific kappaB binding sites by RelB:p52 dimers. EMBO J (2004) 3.32
Stable growth transformation of human T lymphocytes by herpesvirus saimiri. Proc Natl Acad Sci U S A (1992) 2.94
Molecular mechanism of interleukin-8 gene expression. J Leukoc Biol (1994) 2.35
Targeting the NF-kappaB signaling pathway in Notch1-induced T-cell leukemia. Nat Med (2006) 2.35
Unravelling the complexities of the NF-kappaB signalling pathway using mouse knockout and transgenic models. Oncogene (2006) 2.33
Retroviral oncoprotein Tax induces processing of NF-kappaB2/p100 in T cells: evidence for the involvement of IKKalpha. EMBO J (2001) 2.24
Transcription of the RelB gene is regulated by NF-kappaB. Oncogene (2001) 2.01
Epstein-Barr virus-encoded latent infection membrane protein 1 regulates the processing of p100 NF-kappaB2 to p52 via an IKKgamma/NEMO-independent signalling pathway. Oncogene (2003) 1.98
Synthesis and structure-activity relationships of novel IKK-beta inhibitors. Part 3: Orally active anti-inflammatory agents. Bioorg Med Chem Lett (2004) 1.82
A20 inhibits tumor necrosis factor (TNF) alpha-induced apoptosis by disrupting recruitment of TRADD and RIP to the TNF receptor 1 complex in Jurkat T cells. Mol Cell Biol (2002) 1.77
Activation of alternative NF-kappa B pathway by human herpes virus 8-encoded Fas-associated death domain-like IL-1 beta-converting enzyme inhibitory protein (vFLIP). Proc Natl Acad Sci U S A (2004) 1.72
NFkappaB signaling in carcinogenesis and as a potential molecular target for cancer therapy. Apoptosis (2009) 1.71
The product of the Herpesvirus saimiri open reading frame 1 (tip) interacts with T cell-specific kinase p56lck in transformed cells. J Biol Chem (1995) 1.65
Crosstalk via the NF-kappaB signaling system. Cytokine Growth Factor Rev (2008) 1.48
Involvement of two NF-kappa B binding elements in tumor necrosis factor alpha -, CD40-, and epstein-barr virus latent membrane protein 1-mediated induction of the cellular inhibitor of apoptosis protein 2 gene. J Biol Chem (2000) 1.46
STP and Tip are essential for herpesvirus saimiri oncogenicity. J Virol (1998) 1.45
Structural and functional characterization of the promoter regions of the NFKB2 gene. Nucleic Acids Res (1995) 1.28
Two modes of transcriptional activation at native promoters by NF-kappaB p65. PLoS Biol (2009) 1.25
NF-kappaB p52:RelB heterodimer recognizes two classes of kappaB sites with two distinct modes. EMBO Rep (2008) 1.12
In vitro selection of optimal RelB/p52 DNA-binding motifs. Biochem Biophys Res Commun (2007) 1.08
The Kaposi's Sarcoma-associated Herpesvirus-encoded vIRF-3 Inhibits Cellular IRF-5. J Biol Chem (2009) 1.06
Growth inhibition of multiple myeloma cells by a novel IkappaB kinase inhibitor. Clin Cancer Res (2005) 1.05
Role of cellular tumor necrosis factor receptor-associated factors in NF-kappaB activation and lymphocyte transformation by herpesvirus Saimiri STP. J Virol (1999) 1.05
Herpesvirus ateles: properties of an oncogenic herpesvirus isolated from circulating lymphocytes of spider monkeys (Ateles sp.). Int J Cancer (1974) 1.04
The role of NF-kappaB in lymphoid malignancies. Br J Haematol (2008) 0.99
Herpesvirus ateles gene product Tio interacts with nonreceptor protein tyrosine kinases. J Virol (1999) 0.96
Kaposi sarcoma-associated herpesvirus and other viruses in human lymphomagenesis. Curr Top Microbiol Immunol (2007) 0.95
Growth transformation of human T cells by herpesvirus saimiri requires multiple Tip-Lck interaction motifs. J Virol (2006) 0.91
Induction of cell death in adult T-cell leukemia cells by a novel IkappaB kinase inhibitor. Leukemia (2006) 0.90
Herpesvirus ateles Tio can replace herpesvirus saimiri StpC and Tip oncoproteins in growth transformation of monkey and human T cells. J Virol (2004) 0.88
Molecular mechanisms of the effect of herpesvirus saimiri protein StpC on the signaling pathway leading to NF-kappaB activation. J Biol Chem (2004) 0.87
NFkappaB signaling is induced by the oncoprotein Tio through direct interaction with TRAF6. J Biol Chem (2006) 0.85
Tyrosine phosphorylation of the Tio oncoprotein is essential for transformation of primary human T cells. J Virol (2005) 0.81
NF-kappaB activation by the viral oncoprotein StpC enhances IFN-gamma production in T cells. Immunol Cell Biol (2008) 0.78
Revisiting human IL-12Rβ1 deficiency: a survey of 141 patients from 30 countries. Medicine (Baltimore) (2010) 2.33
Structural investigation of the binding of a herpesviral protein to the SH3 domain of tyrosine kinase Lck. Biochemistry (2002) 1.17
Inherited human OX40 deficiency underlying classic Kaposi sarcoma of childhood. J Exp Med (2013) 1.14
Human RHOH deficiency causes T cell defects and susceptibility to EV-HPV infections. J Clin Invest (2012) 1.00
Autoantibodies to GPI and creatine kinase in RA. Nat Immunol (2002) 0.96
Identification of Helicobacter pylori surface proteins by selective proteinase K digestion and antibody phage display. J Microbiol Methods (2005) 0.93
Growth transformation of human T cells by herpesvirus saimiri requires multiple Tip-Lck interaction motifs. J Virol (2006) 0.91
T-cell growth transformation by herpesvirus saimiri is independent of STAT3 activation. J Virol (2005) 0.91
L-Arginine counteracts nitric oxide deficiency and improves the recovery phase of ischemic acute renal failure in rats. Kidney Int (2003) 0.90
Herpesvirus ateles Tio can replace herpesvirus saimiri StpC and Tip oncoproteins in growth transformation of monkey and human T cells. J Virol (2004) 0.88
The insulator protein CTCF binding sites in the orf73/LANA promoter region of herpesvirus saimiri are involved in conferring episomal stability in latently infected human T cells. J Virol (2011) 0.86
NFkappaB signaling is induced by the oncoprotein Tio through direct interaction with TRAF6. J Biol Chem (2006) 0.85
Peripheral T-cell lymphoma in herpesvirus saimiri-infected tamarins: tumor cell lines reveal subgroup-specific differences. Virology (2002) 0.85
Qualitative and quantitative three-dimensional accuracy of a single tooth captured by elastomeric impression materials: an in vitro study. J Prosthet Dent (2012) 0.84
Complexes of monocationic Group 13 elements with pentaphospha- and pentaarsaferrocene. Chemistry (2014) 0.84
Tyrosine phosphorylation of the Tio oncoprotein is essential for transformation of primary human T cells. J Virol (2005) 0.81
Actin-dependent activation of serum response factor in T cells by the viral oncoprotein tip. Cell Commun Signal (2012) 0.80
NF-kappaB activation by the viral oncoprotein StpC enhances IFN-gamma production in T cells. Immunol Cell Biol (2008) 0.78
Transformation efficiency by Herpesvirus saimiri is not a limiting factor in clonal CD8pos T cell outgrowth. Virology (2009) 0.77
Episomal replication timing of gamma-herpesviruses in latently infected cells. Virology (2010) 0.77
Comparative proteome profiling of host-pathogen interactions: insights into the adaptation mechanisms of Francisella tularensis in the host cell environment. Appl Microbiol Biotechnol (2013) 0.77
Noncanonical NF-κB activation by the oncoprotein Tio occurs through a nonconserved TRAF3-binding motif. Sci Signal (2013) 0.76
Species restriction of Herpesvirus saimiri and Herpesvirus ateles: human lymphocyte transformation correlates with distinct signaling properties of viral oncoproteins. Virus Res (2012) 0.76