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Single-molecule dissection of the high-affinity cohesin-dockerin complex. Proc Natl Acad Sci U S A (2012) 1.04

Locating an extracellular K+-dependent interaction site that modulates betaine-binding of the Na+-coupled betaine symporter BetP. Proc Natl Acad Sci U S A (2011) 1.00

Fast-folding alpha-helices as reversible strain absorbers in the muscle protein myomesin. Proc Natl Acad Sci U S A (2011) 0.89

Reference-free alignment and sorting of single-molecule force spectroscopy data. Biophys J (2012) 0.86

Low folding cooperativity of HP35 revealed by single-molecule force spectroscopy and molecular dynamics simulation. Biophys J (2012) 0.84

Isopeptide bonds mechanically stabilize spy0128 in bacterial pili. Biophys J (2013) 0.84

Single-molecule experiments reveal the flexibility of a Per-ARNT-Sim domain and the kinetic partitioning in the unfolding pathway under force. Biophys J (2012) 0.79

Molecular anatomy of a trafficking organelle. Cell (2006) 11.47

Recognition dynamics up to microseconds revealed from an RDC-derived ubiquitin ensemble in solution. Science (2008) 8.04

Yeast kinesin-8 depolymerizes microtubules in a length-dependent manner. Nat Cell Biol (2006) 4.13

Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage. Nat Biotechnol (2011) 3.97

Anatomy and dynamics of a supramolecular membrane protein cluster. Science (2007) 3.75

Hydrostatic pressure and the actomyosin cortex drive mitotic cell rounding. Nature (2011) 2.68

Membrane protein sequestering by ionic protein-lipid interactions. Nature (2011) 2.40

Single-cell force spectroscopy. J Cell Sci (2008) 2.29

Force probing surfaces of living cells to molecular resolution. Nat Chem Biol (2009) 2.28

Effect of sodium chloride on a lipid bilayer. Biophys J (2003) 2.24

Structure and mechanism of the reversible photoswitch of a fluorescent protein. Proc Natl Acad Sci U S A (2005) 2.21

Sequential N- to C-terminal SNARE complex assembly drives priming and fusion of secretory vesicles. EMBO J (2006) 2.19

Mechanoenzymatics of titin kinase. Proc Natl Acad Sci U S A (2008) 2.17

Generalized correlation for biomolecular dynamics. Proteins (2006) 2.17

g_membed: Efficient insertion of a membrane protein into an equilibrated lipid bilayer with minimal perturbation. J Comput Chem (2010) 2.08

Genetic alterations and oncogenic pathways associated with breast cancer subtypes. Mol Cancer Res (2009) 2.05

Control of directed cell migration in vivo by membrane-to-cortex attachment. PLoS Biol (2010) 2.03

Nanoseconds molecular dynamics simulation of primary mechanical energy transfer steps in F1-ATP synthase. Nat Struct Biol (2002) 1.92

Incorporation of pharmacogenomics into routine clinical practice: the Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline development process. Curr Drug Metab (2014) 1.88

The mechanism of proton exclusion in the aquaporin-1 water channel. J Mol Biol (2003) 1.80

Microtubule dynamics reconstituted in vitro and imaged by single-molecule fluorescence microscopy. Methods Cell Biol (2010) 1.76

Force spectroscopy of single biomolecules. Chemphyschem (2002) 1.73

Mechanically induced titin kinase activation studied by force-probe molecular dynamics simulations. Biophys J (2004) 1.70

The dynamics and energetics of water permeation and proton exclusion in aquaporins. Curr Opin Struct Biol (2005) 1.65

Straight GDP-tubulin protofilaments form in the presence of taxol. Curr Biol (2007) 1.59

Single-molecule FRET measures bends and kinks in DNA. Proc Natl Acad Sci U S A (2008) 1.58

Structure and function of water channels. Curr Opin Struct Biol (2002) 1.55

Molecular mechanisms of schizophrenia. Cell Physiol Biochem (2007) 1.53

Transducer binding establishes localized interactions to tune sensory rhodopsin II. Structure (2008) 1.50

Multistep binding of divalent cations to phospholipid bilayers: a molecular dynamics study. Angew Chem Int Ed Engl (2004) 1.50

Revealing early steps of alpha2beta1 integrin-mediated adhesion to collagen type I by using single-cell force spectroscopy. Mol Biol Cell (2007) 1.49

The c15 ring of the Spirulina platensis F-ATP synthase: F1/F0 symmetry mismatch is not obligatory. EMBO Rep (2005) 1.48

Full correlation analysis of conformational protein dynamics. Proteins (2008) 1.47

Quaternary ammonium compounds as water channel blockers. Specificity, potency, and site of action. J Biol Chem (2006) 1.46

Five challenges to bringing single-molecule force spectroscopy into living cells. Nat Methods (2011) 1.45

Kinetics, statistics, and energetics of lipid membrane electroporation studied by molecular dynamics simulations. Biophys J (2008) 1.43

Measuring cell adhesion forces of primary gastrulating cells from zebrafish using atomic force microscopy. J Cell Sci (2005) 1.42

Energy barriers and driving forces in tRNA translocation through the ribosome. Nat Struct Mol Biol (2013) 1.41

Synaptotagmin-1 may be a distance regulator acting upstream of SNARE nucleation. Nat Struct Mol Biol (2011) 1.41

Interaction of urea with amino acids: implications for urea-induced protein denaturation. J Am Chem Soc (2007) 1.39

Phosphatidylinositol 4,5-bisphosphate clusters act as molecular beacons for vesicle recruitment. Nat Struct Mol Biol (2013) 1.38

Water permeation through gramicidin A: desformylation and the double helix: a molecular dynamics study. Biophys J (2002) 1.37

A new technical approach to quantify cell-cell adhesion forces by AFM. Ultramicroscopy (2006) 1.37

Early airway pressure release ventilation prevents ARDS-a novel preventive approach to lung injury. Shock (2013) 1.35

Movement directionality in collective migration of germ layer progenitors. Curr Biol (2010) 1.33

Self-consistent residual dipolar coupling based model-free analysis for the robust determination of nanosecond to microsecond protein dynamics. J Biomol NMR (2008) 1.33

Computational electrophysiology: the molecular dynamics of ion channel permeation and selectivity in atomistic detail. Biophys J (2011) 1.30

Membrane fusion. Curr Opin Cell Biol (2002) 1.29

How SNARE molecules mediate membrane fusion: recent insights from molecular simulations. Curr Opin Struct Biol (2012) 1.26

Bacteriorhodopsin folds into the membrane against an external force. J Mol Biol (2006) 1.26

Mechanical properties of the icosahedral shell of southern bean mosaic virus: a molecular dynamics study. Biophys J (2009) 1.26

Caught in the act: visualization of SNARE-mediated fusion events in molecular detail. Chembiochem (2011) 1.25

The c13 ring from a thermoalkaliphilic ATP synthase reveals an extended diameter due to a special structural region. J Mol Biol (2009) 1.23

Speeding up parallel GROMACS on high-latency networks. J Comput Chem (2007) 1.23

Detecting protein-induced folding of the U4 snRNA kink-turn by single-molecule multiparameter FRET measurements. RNA (2005) 1.23

Simulation of fluorescence anisotropy experiments: probing protein dynamics. Biophys J (2005) 1.21

Oncogenic activating mutations are associated with local copy gain. Mol Cancer Res (2009) 1.21

Differential peptide dynamics is linked to major histocompatibility complex polymorphism. J Biol Chem (2004) 1.19

Collective Langevin dynamics of conformational motions in proteins. J Chem Phys (2006) 1.18

Structural heterogeneity and quantitative FRET efficiency distributions of polyprolines through a hybrid atomistic simulation and Monte Carlo approach. PLoS One (2011) 1.16

Quantifying cellular adhesion to extracellular matrix components by single-cell force spectroscopy. Nat Protoc (2010) 1.16

Conformational adaptability of Redbeta during DNA annealing and implications for its structural relationship with Rad52. J Mol Biol (2009) 1.16

Aqueous urea solutions: structure, energetics, and urea aggregation. J Phys Chem B (2007) 1.16

Locating ligand binding and activation of a single antiporter. EMBO Rep (2005) 1.15

Hepatic knockdown of mitochondrial GPAT1 in ob/ob mice improves metabolic profile. Biochem Biophys Res Commun (2006) 1.13

Can principal components yield a dimension reduced description of protein dynamics on long time scales? J Phys Chem B (2006) 1.12

Rapid glycation with D-ribose induces globular amyloid-like aggregations of BSA with high cytotoxicity to SH-SY5Y cells. BMC Cell Biol (2009) 1.11

The oligomeric state of c rings from cyanobacterial F-ATP synthases varies from 13 to 15. J Bacteriol (2007) 1.11

Quantitative structural analysis of importin-β flexibility: paradigm for solenoid protein structures. Structure (2010) 1.11

Contributions of galectin-3 and -9 to epithelial cell adhesion analyzed by single cell force spectroscopy. J Biol Chem (2007) 1.10

Mechanical properties of single motor molecules studied by three-dimensional thermal force probing in optical tweezers. Chemphyschem (2004) 1.09

Constant pH Molecular Dynamics in Explicit Solvent with λ-Dynamics. J Chem Theory Comput (2011) 1.09

Observing growth steps of collagen self-assembly by time-lapse high-resolution atomic force microscopy. J Struct Biol (2006) 1.08

Galectin-3 regulates integrin alpha2beta1-mediated adhesion to collagen-I and -IV. J Biol Chem (2008) 1.08

Kinetics of conformational sampling in ubiquitin. Angew Chem Int Ed Engl (2011) 1.07

Photoswitching of the fluorescent protein asFP595: mechanism, proton pathways, and absorption spectra. Angew Chem Int Ed Engl (2007) 1.06

Correction: Spatiotemporal Scan and Age-Period-Cohort Analysis of Hepatitis C Virus in Henan, China: 2005-2012. PLoS One (2015) 1.06

Enzymatic characterization of the pancreatic islet-specific glucose-6-phosphatase-related protein (IGRP). J Biol Chem (2004) 1.06

A bond for a lifetime: employing membrane nanotubes from living cells to determine receptor-ligand kinetics. Angew Chem Int Ed Engl (2008) 1.05

Aminosulfonate modulated pH-induced conformational changes in connexin26 hemichannels. J Biol Chem (2007) 1.05

Stabilizing effect of Zn2+ in native bovine rhodopsin. J Biol Chem (2007) 1.05

Influenza virus binds its host cell using multiple dynamic interactions. Proc Natl Acad Sci U S A (2012) 1.05

Anti-inflammatory and analgesic effect of plumbagin through inhibition of nuclear factor-κB activation. J Pharmacol Exp Ther (2010) 1.04

Characterizing molecular interactions in different bacteriorhodopsin assemblies by single-molecule force spectroscopy. J Mol Biol (2005) 1.04

Cellular remodelling of individual collagen fibrils visualized by time-lapse AFM. J Mol Biol (2007) 1.04

Ultrafast deactivation channel for thymine dimerization. J Am Chem Soc (2007) 1.04

Torsional elasticity and energetics of F1-ATPase. Proc Natl Acad Sci U S A (2011) 1.03

Tudor-SN interacts with and co-localizes with G3BP in stress granules under stress conditions. FEBS Lett (2010) 1.03

An intermediate step in the evolution of ATPases: a hybrid F(0)-V(0) rotor in a bacterial Na(+) F(1)F(0) ATP synthase. FEBS J (2008) 1.03

An unusual hydrophobic core confers extreme flexibility to HEAT repeat proteins. Biophys J (2010) 1.02

Dynamics and energetics of permeation through aquaporins. What do we learn from molecular dynamics simulations? Handb Exp Pharmacol (2009) 1.02

Human Tau isoforms assemble into ribbon-like fibrils that display polymorphic structure and stability. J Biol Chem (2010) 1.02