Published in Nat Protoc on July 01, 2010
The cancer glycocalyx mechanically primes integrin-mediated growth and survival. Nature (2014) 1.96
Kindlin-2 cooperates with talin to activate integrins and induces cell spreading by directly binding paxillin. Elife (2016) 1.04
Neuropilin-2 promotes extravasation and metastasis by interacting with endothelial α5 integrin. Cancer Res (2013) 0.94
Tracking mechanics and volume of globular cells with atomic force microscopy using a constant-height clamp. Nat Protoc (2012) 0.91
Quantifying the forces driving cell-cell adhesion in a fungal pathogen. Langmuir (2013) 0.86
Single-Cell Force Spectroscopy of Als-Mediated Fungal Adhesion. Anal Methods (2013) 0.84
Syntenin-1 and ezrin proteins link activated leukocyte cell adhesion molecule to the actin cytoskeleton. J Biol Chem (2014) 0.83
Covalent and density-controlled surface immobilization of E-cadherin for adhesion force spectroscopy. PLoS One (2014) 0.81
Conformational coupling of integrin and Thy-1 regulates Fyn priming and fibroblast mechanotransduction. J Cell Biol (2015) 0.80
Phenotypic, Morphological and Adhesive Differences of Human Hematopoietic Progenitor Cells Cultured on Murine versus Human Mesenchymal Stromal Cells. Sci Rep (2015) 0.79
Cell Membrane Proteins Modulate the Carbon Nanotube Optical Bandgap via Surface Charge Accumulation. ACS Nano (2015) 0.79
Increasing throughput of AFM-based single cell adhesion measurements through multisubstrate surfaces. Beilstein J Nanotechnol (2015) 0.79
αV-integrins are required for mechanotransduction in MDCK epithelial cells. PLoS One (2013) 0.79
Combined single cell AFM manipulation and TIRFM for probing the molecular stability of multilayer fibrinogen matrices. Ultramicroscopy (2013) 0.77
Cell substratum adhesion during early development of Dictyostelium discoideum. PLoS One (2014) 0.77
In PC3 prostate cancer cells ephrin receptors crosstalk to β1-integrins to strengthen adhesion to collagen type I. Sci Rep (2015) 0.77
Migratory and adhesive properties of Xenopus laevis primordial germ cells in vitro. Biol Open (2013) 0.76
Semi-quantitative monitoring of confluence of adherent mesenchymal stromal cells on calcium-phosphate granules by using widefield microscopy images. J Mater Sci Mater Med (2014) 0.76
Stamping vital cells - a force-based ligand receptor assay. Biophys J (2013) 0.76
Reinforcement of integrin-mediated T-Lymphocyte adhesion by TNF-induced Inside-out Signaling. Sci Rep (2016) 0.76
Exchangeable colloidal AFM probes for the quantification of irreversible and long-term interactions. Biophys J (2013) 0.76
Nano-mechanical Phenotype as a Promising Biomarker to Evaluate Cancer Development, Progression, and Anti-cancer Drug Efficacy. J Cancer Prev (2016) 0.75
Quantifying Molecular-Level Cell Adhesion on Electroactive Conducting Polymers using Electrochemical-Single Cell Force Spectroscopy. Sci Rep (2015) 0.75
Unraveling the Receptor-Ligand Interactions between Bladder Cancer Cells and the Endothelium Using AFM. Biophys J (2017) 0.75
αV-class integrins exert dual roles on α5β1 integrins to strengthen adhesion to fibronectin. Nat Commun (2017) 0.75
Fibronectin-bound α5β1 integrins sense load and signal to reinforce adhesion in less than a second. Nat Mater (2017) 0.75
Zebrafish In-Vivo Screening for Compounds Amplifying Hematopoietic Stem and Progenitor Cells: - Preclinical Validation in Human CD34+ Stem and Progenitor Cells. Sci Rep (2017) 0.75
N-glycan mediated adhesion strengthening during pathogen-receptor binding revealed by cell-cell force spectroscopy. Sci Rep (2017) 0.75
The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors. Cell (1992) 30.02
Adhesion forces between individual ligand-receptor pairs. Science (1994) 11.62
Intermolecular forces and energies between ligands and receptors. Science (1994) 7.44
FAK integrates growth-factor and integrin signals to promote cell migration. Nat Cell Biol (2000) 6.54
Elastic area compressibility modulus of red cell membrane. Biophys J (1976) 6.13
Formation of actin stress fibers and focal adhesions enhanced by Rho-kinase. Science (1997) 5.80
Assembly dynamics of microtubules at molecular resolution. Nature (2006) 5.52
Sensitive force technique to probe molecular adhesion and structural linkages at biological interfaces. Biophys J (1995) 5.45
Consequences of lack of beta 1 integrin gene expression in mice. Genes Dev (1995) 4.89
Isolation of a collagen-dependent cell attachment factor. Nature (1974) 3.81
Discrete interactions in cell adhesion measured by single-molecule force spectroscopy. Nat Cell Biol (2000) 2.94
Forces and bond dynamics in cell adhesion. Science (2007) 2.88
Granulocyte-endothelium initial adhesion. Analysis of transient binding events mediated by E-selectin in a laminar shear flow. Biophys J (1993) 2.86
Intermolecular forces in biology. Q Rev Biophys (2001) 2.77
Polyphenolic Substance of Mytilus edulis: Novel Adhesive Containing L-Dopa and Hydroxyproline. Science (1981) 2.65
Force spectroscopy of the leukocyte function-associated antigen-1/intercellular adhesion molecule-1 interaction. Biophys J (2002) 2.44
Single-cell force spectroscopy. J Cell Sci (2008) 2.29
Integrin modulation and signaling in leukocyte adhesion and migration. Immunol Rev (2007) 2.10
Embryonic lethal mutation in mouse collagen I gene causes rupture of blood vessels and is associated with erythropoietic and mesenchymal cell death. Cell (1984) 2.03
Disruption of the talin gene arrests mouse development at the gastrulation stage. Dev Dyn (2000) 1.98
Determination of junction avidity of cytolytic T cell and target cell. Science (1986) 1.88
Single integrin molecule adhesion forces in intact cells measured by atomic force microscopy. Biochem Biophys Res Commun (1999) 1.74
Revealing early steps of alpha2beta1 integrin-mediated adhesion to collagen type I by using single-cell force spectroscopy. Mol Biol Cell (2007) 1.49
Evidence for a repeating 3,4-dihydroxyphenylalanine- and hydroxyproline-containing decapeptide in the adhesive protein of the mussel, Mytilus edulis L. J Biol Chem (1983) 1.43
Measuring cell adhesion forces of primary gastrulating cells from zebrafish using atomic force microscopy. J Cell Sci (2005) 1.42
Quantification of cell adhesion using a spinning disc device and application to surface-reactive materials. Biomaterials (1997) 1.29
Measuring cell adhesion forces with the atomic force microscope at the molecular level. Cells Tissues Organs (2002) 1.23
Hydrodynamic effects in fast AFM single-molecule force measurements. Eur Biophys J (2004) 1.23
Affinity imaging of red blood cells using an atomic force microscope. J Histochem Cytochem (2000) 1.20
Contributions of galectin-3 and -9 to epithelial cell adhesion analyzed by single cell force spectroscopy. J Biol Chem (2007) 1.10
Galectin-3 regulates integrin alpha2beta1-mediated adhesion to collagen-I and -IV. J Biol Chem (2008) 1.08
A centrifugation cell adhesion assay for high-throughput screening of biomaterial surfaces. J Biomed Mater Res A (2003) 1.07
Functionalized biomicroelectromechanical systems sensors for force response study at local adhesion sites of single living cells on substrates. Ann Biomed Eng (2003) 0.97
Cell adhesion measured by force spectroscopy on living cells. Methods Cell Biol (2002) 0.93
Analysis of ligand-receptor interactions in cells by atomic force microscopy. J Recept Signal Transduct Res (2002) 0.90
Regulation of protrusive and contractile cell-matrix contacts. J Cell Sci (2002) 0.89
TPA primes alpha2beta1 integrins for cell adhesion. FEBS Lett (2008) 0.88
Strategies and results of atomic force microscopy in the study of cellular adhesion. Micron (2005) 0.83
Micromechanical cantilever array sensors for selective fungal immobilization and fast growth detection. Biosens Bioelectron (2005) 0.83
Getting a grip: new insights for cell adhesion and traction. Nat Cell Biol (2001) 0.78
Yeast kinesin-8 depolymerizes microtubules in a length-dependent manner. Nat Cell Biol (2006) 4.13
Hydrostatic pressure and the actomyosin cortex drive mitotic cell rounding. Nature (2011) 2.68
Single-cell force spectroscopy. J Cell Sci (2008) 2.29
Force probing surfaces of living cells to molecular resolution. Nat Chem Biol (2009) 2.28
Control of directed cell migration in vivo by membrane-to-cortex attachment. PLoS Biol (2010) 2.03
Incorporation of pharmacogenomics into routine clinical practice: the Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline development process. Curr Drug Metab (2014) 1.88
Microtubule dynamics reconstituted in vitro and imaged by single-molecule fluorescence microscopy. Methods Cell Biol (2010) 1.76
Straight GDP-tubulin protofilaments form in the presence of taxol. Curr Biol (2007) 1.59
Molecular mechanisms of schizophrenia. Cell Physiol Biochem (2007) 1.53
Transducer binding establishes localized interactions to tune sensory rhodopsin II. Structure (2008) 1.50
Revealing early steps of alpha2beta1 integrin-mediated adhesion to collagen type I by using single-cell force spectroscopy. Mol Biol Cell (2007) 1.49
The c15 ring of the Spirulina platensis F-ATP synthase: F1/F0 symmetry mismatch is not obligatory. EMBO Rep (2005) 1.48
Five challenges to bringing single-molecule force spectroscopy into living cells. Nat Methods (2011) 1.45
Measuring cell adhesion forces of primary gastrulating cells from zebrafish using atomic force microscopy. J Cell Sci (2005) 1.42
A new technical approach to quantify cell-cell adhesion forces by AFM. Ultramicroscopy (2006) 1.37
Movement directionality in collective migration of germ layer progenitors. Curr Biol (2010) 1.33
Bacteriorhodopsin folds into the membrane against an external force. J Mol Biol (2006) 1.26
The c13 ring from a thermoalkaliphilic ATP synthase reveals an extended diameter due to a special structural region. J Mol Biol (2009) 1.23
Conformational adaptability of Redbeta during DNA annealing and implications for its structural relationship with Rad52. J Mol Biol (2009) 1.16
Locating ligand binding and activation of a single antiporter. EMBO Rep (2005) 1.15
The oligomeric state of c rings from cyanobacterial F-ATP synthases varies from 13 to 15. J Bacteriol (2007) 1.11
Contributions of galectin-3 and -9 to epithelial cell adhesion analyzed by single cell force spectroscopy. J Biol Chem (2007) 1.10
Observing growth steps of collagen self-assembly by time-lapse high-resolution atomic force microscopy. J Struct Biol (2006) 1.08
Galectin-3 regulates integrin alpha2beta1-mediated adhesion to collagen-I and -IV. J Biol Chem (2008) 1.08
A bond for a lifetime: employing membrane nanotubes from living cells to determine receptor-ligand kinetics. Angew Chem Int Ed Engl (2008) 1.05
Aminosulfonate modulated pH-induced conformational changes in connexin26 hemichannels. J Biol Chem (2007) 1.05
Stabilizing effect of Zn2+ in native bovine rhodopsin. J Biol Chem (2007) 1.05
Characterizing molecular interactions in different bacteriorhodopsin assemblies by single-molecule force spectroscopy. J Mol Biol (2005) 1.04
Cellular remodelling of individual collagen fibrils visualized by time-lapse AFM. J Mol Biol (2007) 1.04
An intermediate step in the evolution of ATPases: a hybrid F(0)-V(0) rotor in a bacterial Na(+) F(1)F(0) ATP synthase. FEBS J (2008) 1.03
Human Tau isoforms assemble into ribbon-like fibrils that display polymorphic structure and stability. J Biol Chem (2010) 1.02
Point mutations in membrane proteins reshape energy landscape and populate different unfolding pathways. J Mol Biol (2007) 1.02
Locating an extracellular K+-dependent interaction site that modulates betaine-binding of the Na+-coupled betaine symporter BetP. Proc Natl Acad Sci U S A (2011) 1.00
Mechanical properties of bovine rhodopsin and bacteriorhodopsin: possible roles in folding and function. Langmuir (2008) 0.99
Evidence of association between smoking and alpha7 nicotinic receptor subunit gene in schizophrenia patients. Neuropsychopharmacology (2004) 0.97
Actomyosin contractility controls cell surface area of oligodendrocytes. BMC Cell Biol (2009) 0.97
Structural evidence for a constant c11 ring stoichiometry in the sodium F-ATP synthase. FEBS J (2005) 0.96
Imaging and quantifying chemical and physical properties of native proteins at molecular resolution by force-volume AFM. Angew Chem Int Ed Engl (2011) 0.96
Studying integrin-mediated cell adhesion at the single-molecule level using AFM force spectroscopy. Sci STKE (2007) 0.95
Kinetic, energetic, and mechanical differences between dark-state rhodopsin and opsin. Structure (2013) 0.95
An approach to prepare membrane proteins for single-molecule imaging. Angew Chem Int Ed Engl (2006) 0.95
The effect of unlocking RGD-motifs in collagen I on pre-osteoblast adhesion and differentiation. Biomaterials (2010) 0.95
Wedged AFM-cantilevers for parallel plate cell mechanics. Methods (2013) 0.93
A novel pattern recognition algorithm to classify membrane protein unfolding pathways with high-throughput single-molecule force spectroscopy. Bioinformatics (2007) 0.93
Transmembrane helices have rough energy surfaces. J Am Chem Soc (2007) 0.93
Differentiating ligand and inhibitor interactions of a single antiporter. J Mol Biol (2006) 0.93
Free energy of membrane protein unfolding derived from single-molecule force measurements. Biophys J (2007) 0.92
pH-dependent interactions guide the folding and gate the transmembrane pore of the beta-barrel membrane protein OmpG. J Mol Biol (2010) 0.91
Competing interactions stabilize pro- and anti-aggregant conformations of human Tau. J Biol Chem (2011) 0.90
BCR/ABL expression of myeloid progenitors increases beta1-integrin mediated adhesion to stromal cells. J Mol Biol (2008) 0.90
Stimulated single-cell force spectroscopy to quantify cell adhesion receptor crosstalk. Proteomics (2010) 0.90
Substrate binding tunes conformational flexibility and kinetic stability of an amino acid antiporter. J Biol Chem (2009) 0.89
pH-induced conformational change of the beta-barrel-forming protein OmpG reconstituted into native E. coli lipids. J Mol Biol (2009) 0.89
TPA primes alpha2beta1 integrins for cell adhesion. FEBS Lett (2008) 0.88
Dynamic coupling of ALCAM to the actin cortex strengthens cell adhesion to CD6. J Cell Sci (2014) 0.87
A "force buffer" protecting immunoglobulin titin. Angew Chem Int Ed Engl (2010) 0.87
Force probing cell shape changes to molecular resolution. Trends Biochem Sci (2011) 0.87
Detecting molecular interactions that stabilize, activate and guide ligand-binding of the sodium/proton antiporter MjNhaP1 from Methanococcus jannaschii. J Struct Biol (2007) 0.86
Single-cell force spectroscopy, an emerging tool to quantify cell adhesion to biomaterials. Tissue Eng Part B Rev (2013) 0.85
Role of extracellular glutamic acids in the stability and energy landscape of bacteriorhodopsin. Biophys J (2008) 0.85
Dual energy landscape: the functional state of the β-barrel outer membrane protein G molds its unfolding energy landscape. Proteomics (2010) 0.84
One beta hairpin after the other: exploring mechanical unfolding pathways of the transmembrane beta-barrel protein OmpG. Angew Chem Int Ed Engl (2009) 0.84
Examining the dynamic energy landscape of an antiporter upon inhibitor binding. J Mol Biol (2007) 0.84
Imaging and detecting molecular interactions of single transmembrane proteins. Neurobiol Aging (2005) 0.84
Folding and assembly of proteorhodopsin. J Mol Biol (2007) 0.83
Observing folding pathways and kinetics of a single sodium-proton antiporter from Escherichia coli. J Mol Biol (2005) 0.83
Studying collagen self-assembly by time-lapse high-resolution atomic force microscopy. Methods Mol Biol (2011) 0.82
Observing fibrillar assemblies on scrapie-infected cells. Pflugers Arch (2008) 0.81
Narrow-band UVB-induced externalization of selected nuclear antigens in keratinocytes: implications for lupus erythematosus pathogenesis. Photochem Photobiol (2008) 0.80
αV-integrins are required for mechanotransduction in MDCK epithelial cells. PLoS One (2013) 0.79
Creating ultrathin nanoscopic collagen matrices for biological and biotechnological applications. Small (2007) 0.79
Surface morphology and mechanical properties of fibroblasts from scleroderma patients. J Cell Mol Med (2009) 0.78
Structural alterations provoked by narrow-band ultraviolet B in immortalized keratinocytes: assessment by atomic force microscopy. Exp Dermatol (2007) 0.76
Analysis assistant for single-molecule force spectroscopy data on membrane proteins--MPTV. Bioinformatics (2006) 0.75
Investigating fibrillar aggregates of Tau protein by atomic force microscopy. Methods Mol Biol (2012) 0.75