Published in Am J Physiol on May 01, 1991
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TGFβ receptor signaling is essential for inflammation-induced but not β-cell workload-induced β-cell proliferation. Diabetes (2012) 1.21
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Thrombospondin-1: an islet endothelial cell signal of importance for β-cell function. Diabetes (2011) 0.96
Differential synthesis and action of TGFß superfamily ligands in mouse and rat islets. Islets (2011) 0.87
Enhanced stimulus-secretion coupling in polyamine-depleted rat insulinoma cells. An effect involving increased cytoplasmic Ca2+, inositol phosphate generation, and phorbol ester sensitivity. J Clin Invest (1993) 0.83
Sustained beta-cell dysfunction but normalized islet mass in aged thrombospondin-1 deficient mice. PLoS One (2012) 0.80
Repression of a potassium channel by nuclear hormone receptor and TGF-β signaling modulates insulin signaling in Caenorhabditis elegans. PLoS Genet (2012) 0.79
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A Transient Metabolic Recovery from Early Life Glucose Intolerance in Cystic Fibrosis Ferrets Occurs During Pancreatic Remodeling. Endocrinology (2016) 0.76
Transplantation of porcine fetal pancreas to diabetic patients. Lancet (1994) 2.52
Prolonged exposure of human pancreatic islets to high glucose concentrations in vitro impairs the beta-cell function. J Clin Invest (1992) 1.95
Major species differences between humans and rodents in the susceptibility to pancreatic beta-cell injury. Proc Natl Acad Sci U S A (1994) 1.76
Effects of carbohydrates on the oxygen consumption of isolated pancreatic islets of mice. Endocrinology (1967) 1.64
Cytokines suppress human islet function irrespective of their effects on nitric oxide generation. J Clin Invest (1994) 1.48
Inhibitory effects of interleukin 1 on insulin secretion, insulin biosynthesis, and oxidative metabolism of isolated rat pancreatic islets. Endocrinology (1987) 1.45
Cellular localization of somatostatin in endocrine-like cells and neurons of the rat with special references to the A1-cells of the pancreatic islets and to the hypothalamus. Acta Endocrinol Suppl (Copenh) (1975) 1.34
Rapid deposition of amyloid in human islets transplanted into nude mice. Diabetologia (1995) 1.23
Glucose stimulation of insulin secretion from the isolated pancreas of foetal and newborn rats. Diabetologia (1969) 1.22
Failure of glucose to elicit a normal secretory response in fetal pancreatic beta cells results from glucose insensitivity of the ATP-regulated K+ channels. Proc Natl Acad Sci U S A (1989) 1.19
Effects of glucose on the ultrastructure and insulin biosynthesis of isolated mouse pancreatic islets maintained in tissue culture. Diabetologia (1974) 1.16
Human pancreatic beta-cell deoxyribonucleic acid-synthesis in islet grafts decreases with increasing organ donor age but increases in response to glucose stimulation in vitro. Endocrinology (1996) 1.16
Diabetes in pregnancy: effects on the foetal and newborn rat with particular regard to body weight, serum insulin concentration and pancreatic contents of insulin, glucagon and somatostatin. Acta Endocrinol (Copenh) (1980) 1.15
Increased incidence of congenital malformations in the offspring of diabetic rats and their prevention by maternal insulin therapy. Diabetes (1982) 1.12
Impairment of glucose-induced insulin secretion in human pancreatic islets transplanted to diabetic nude mice. J Clin Invest (1995) 1.08
Biosynthesis of glucagon in isolated pancreatic islets of guinea pigs. Biochem J (1974) 1.08
Stimulation by glucose of the blood flow to the pancreatic islets of the rat. Diabetologia (1983) 1.07
Multiple low-dose streptozotocin-induced diabetes in the mouse. Evidence for stimulation of a cytotoxic cellular immune response against an insulin-producing beta cell line. J Clin Invest (1984) 1.05
The stimulus-secretion coupling of amino acid-induced insulin release. Metabolic response of pancreatic islets of L-glutamine and L-leucine. J Biol Chem (1982) 1.05
Nitric oxide donors decrease the function and survival of human pancreatic islets. Mol Cell Endocrinol (1996) 1.04
Oxidation of glucose and fatty acids in normal and in A 2 -cell rich pancreatic islets isolated from guinea-pigs. Diabetologia (1972) 1.02
Cytotoxic effects of streptozotocin and N-nitrosomethylurea on the pancreatic B cells with special regard to the role of nicotinamide-adenine dinucleotide. Biochem J (1974) 1.01
Structure and metabolism of the pancreatic islets in streptozotocin treated guinea pigs. Horm Metab Res (1970) 1.01
The life story of the pancreatic B cell. Diabetologia (1984) 1.01
Effects of glucose and amino acids on the biosynthesis of DNA and insulin in fetal rat islets maintained in tissue culture. Diabetes (1980) 1.00
A rapid method of visualizing the pancreatic islets for studies of islet capillary blood flow using non-radioactive microspheres. Acta Physiol Scand (1981) 0.99
Glucose-induced changes in pancreatic islet blood flow mediated by central nervous system. Am J Physiol (1986) 0.98
Metabolic characteristics of isolated pancreatic islets in tissue culture. Diabetes (1972) 0.97
[Bioenergetics of islet function: oxygen utilization and oxidative metabolism in the beta-cells]. Acta Diabetol Lat (1970) 0.96
Long-term effects of cyclosporin A on cultured mouse pancreatic islets. Diabetologia (1984) 0.96
Regeneration of islet cells. Acta Endocrinol Suppl (Copenh) (1976) 0.95
Participation of endogenous fatty acids in the secretory activity of the pancreatic B-cell. Biochem J (1985) 0.94
Differential effects of age versus glycemic stimulation on the maturation of insulin stimulus-secretion coupling during culture of fetal rat islets. Diabetes (1984) 0.94
Glucose regulation of the autoantigen GAD65 in human pancreatic islets. J Clin Endocrinol Metab (1992) 0.93
Preferential reduction of insulin production in mouse pancreatic islets maintained in culture after streptozotocin exposure. Endocrinology (1988) 0.93
Effects in vitro of alloxan on the glucose metabolism of mouse pancreatic B-cells. Biochem J (1979) 0.91
Acute effects of alloxan on the metabolism and insulin secretion of the pancreatic B-cell. Horm Metab Res (1973) 0.91
Insulin production and glucose metabolism in isolated pancreatic islets of rats with NIDDM. Diabetes (1988) 0.90
Mechanism of 3-phenylpyruvate-induced insulin release. Metabolic aspects. Biochem J (1983) 0.90
Tissue culture of A 2 cell-rich pancreatic islets isolated from guinea pigs. J Cell Biol (1973) 0.89
Effects of glucosamine on the respiration of pancreatic islet B-cells. Acta Endocrinol (Copenh) (1968) 0.89
Differences in amyloid deposition in islets of transgenic mice expressing human islet amyloid polypeptide versus human islets implanted into nude mice. Metabolism (1999) 0.89
Respiration of the pancreatic B-cell: effects of glucose and 2-aminonorbornane-2-carboxylic acid. Horm Metab Res Suppl (1980) 0.88
The cell types in the endocrine pancreas of the human fetus. Z Zellforsch Mikrosk Anat (1966) 0.87
In vitro restoration of insulin production in islets from adult rats treated neonatally with streptozotocin. Endocrinology (1990) 0.87
Role of zinc and calcium in the formation and storage of insulin in the pancreatic beta-cell. Cell Tissue Res (1978) 0.87
Role of polyamines in mitogenic and secretory responses of pancreatic beta-cells to growth factors. Am J Physiol (1990) 0.86
Oxygen consumption of isolated pancreatic islets of mice studied with the cartesian-diver micro-gasometer. Biochem J (1966) 0.86
Glucose metabolism of pancreatic islets isolated from neonatal rats. Horm Metab Res (1972) 0.86
Predominance of stimulatory effects of interleukin-1 beta on isolated human pancreatic islets. J Clin Endocrinol Metab (1993) 0.85
Long-term effects of a high glucose concentration in vitro on the oxidative metabolism and insulin production of isolated rat pancreatic islets. Metabolism (1991) 0.85
Respiration and insulin release in mouse pancreatic islets. Effects of L-leucine and 2-ketoisocaproate in combination with D-glucose and L-glutamine. Biochim Biophys Acta (1982) 0.84
Survival of isolated human islets of Langerhans maintained in tissue culture. J Clin Invest (1976) 0.84
Diabetes in pregnancy. Skeletal malformations in the offspring of diabetic rats after intermittent withdrawal of insulin in early gestation. Diabetes (1983) 0.84
Effects of high glucose concentrations on the insulin biosynthesis of rat pancreatic islets maintained for extended periods in tissue culture. Diabete Metab (1981) 0.84
Long-term effects of a low extracellular glucose concentration on glucose metabolism and insulin biosynthesis and release of mouse pancreatic islets maintained in tissue culture. Acta Endocrinol (Copenh) (1976) 0.84
Tissue culture of human fetal pancreas. Effects of nicotinamide on insulin production and formation of isletlike cell clusters. Diabetes (1989) 0.84
Ultrastructure of monolayer cultures of pancreatic islet cells. Acta Diabetol Lat (1971) 0.83
Effects of D-glucose, L-leucine, and 2-ketoisocaproate on insulin mRNA levels in mouse pancreatic islets. Diabetes (1986) 0.83
Induction of alloxan diabetes in obese-hyperglycemic mice (genotype obob). Experientia (1973) 0.83
Effects of D-glyceraldehyde and D-glucose of the insulin release of pancreatic islets isolated from the newborn rat. FEBS Lett (1976) 0.83
Radioautographic localization of labelled proteins after incubation of guinea-pig islets of Langerhans with (3H)tryptophan. Biochem J (1974) 0.83
Mechanism of 3-phenylpyruvate-induced insulin release. Secretory, ionic and oxidative aspects. Biochem J (1983) 0.83
The structure and hormone content of the endocrine pancreas of the one-humped camel (Camelus dromedarius). Anat Anz (1985) 0.83
Tissue culture of human fetal pancreas. Development and function of B-cells in vitro and transplantation of explants to nude mice. Diabetes (1985) 0.83
Diet-induced obesity and pancreatic islet blood flow in the rat: a preferential increase in islet blood perfusion persists after withdrawal of the diet and normalization of body weight. J Endocrinol (1996) 0.82
Effects of platelet-derived growth factor and somatomedin-C/insulin-like growth factor I on the deoxyribonucleic acid replication of fetal rat islets of Langerhans in tissue culture. Endocrinology (1988) 0.82
Mechanisms of defective glucose-induced insulin release in human pancreatic islets transplanted to diabetic nude mice. J Clin Endocrinol Metab (1997) 0.82
Nicotinamide decreases nitric oxide production and partially protects human pancreatic islets against the suppressive effects of combinations of cytokines. Autoimmunity (1994) 0.82
Mechanisms of leucine- and theophylline-stimulated insulin biosynthesis in isolated rat pancreatic islets. Biochem J (1987) 0.81
Assessment of insulin secretion in vitro from microencapsulated fetal porcine islet-like cell clusters and rat, mouse, and human pancreatic islets. Transplantation (1997) 0.81
Engraftment and growth of transplanted pancreatic islets. Ups J Med Sci (2000) 0.81
Lithium increases DNA replication, polyamine content, and insulin secretion by rat pancreatic beta-cells. Am J Physiol (1992) 0.81
Use of liposomes to introduce substances into pancreatic islet cells. Diabetes (1988) 0.81
In vitro regulation of insulin release and biosynthesis of fetal rat pancreatic cells explanted on pregnancy day 16. Biol Neonate (1997) 0.81
Opposite effects of D-glucose and a nonmetabolized analogue of L-leucine on respiration and secretion in insulin-producing tumoral cells (RINm5F). Diabetes (1987) 0.81
Increased glucose oxidation and contents of insulin and ATP in polyamine-depleted rat insulinoma cells (RINm5F). Biochem J (1991) 0.81
Effects of somatostatin on the biosynthesis and release of insulin from isolated pancreatic islets. Diabete Metab (1976) 0.81
Phase-contrast microscopy of fresh and cultured pancreatic islet cells of guinea-pigs. Z Zellforsch Mikrosk Anat (1967) 0.80
Is there an animal model for gestational diabetes? Diabetes (1985) 0.80
Phylogenetic aspects of somatostatin in the gastroenteropancreatic (GEP) endocrine system. Metabolism (1978) 0.80
Quantitative studies on isolated pancreatic islets of mammals: enzymic hydrolysis of nucleoside diphosphates and rho-nitrophenyl phosphate in normal and cortisone-treated rats. J Endocrinol (1966) 0.80
Long term inhibitory effects of pancreastatin and diazepam binding inhibitor on pancreatic beta-cell deoxyribonucleic acid replication, polyamine content, and insulin secretion. Endocrinology (1991) 0.80
Transplantation of porcine fetal pancreas to a diabetic patient. Transplant Proc (1992) 0.79
Evidence of xenograft function in a diabetic patient grafted with porcine fetal pancreas. Transplant Proc (1992) 0.79
Decreased cyclic AMP and insulin response to glucose in isolated islets of neonatal rats. Diabetes (1975) 0.79
Letter: Diabetogenic nitrosamines? Lancet (1974) 0.79
Effects of glucose, leucine and adenosine on insulin release, 45Ca2+ net uptake, NADH/NAD ratios and oxygen consumption of islets isolated from fed and starved mice. Mol Cell Endocrinol (1983) 0.79
Morphologic study of cultured pancreatic fetal islets during maturation of the insulin stimulus-secretion mechanism. Diabetes (1980) 0.79
Transplantation of fetal pancreatic microfragments via the portal vein to a diabetic patient. Diabetes (1980) 0.78
Release of insulin in vitro from normal and duct-ligated rat pancreas. Acta Pathol Microbiol Scand A (1979) 0.78
The growth hormone dependent incor- poration of sulphate into the costal cartilage of obese-hyperglycaemic mice of different ages. Acta Endocrinol (Copenh) (1970) 0.78
Pig-to-human islet transplantation in eight patients. Transplant Proc (1994) 0.78
Glucose metabolism in vitro of cultured and transplanted mouse pancreatic islets microencapsulated by means of a high-voltage electrostatic field. Diabetes Care (1999) 0.78
Explant culture: pancreatic islets. Methods Cell Biol (1980) 0.78