David Dawbarn

Author PubWeight™ 17.87‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Clinical relevance of the neurotrophins and their receptors. Clin Sci (Lond) 2006 1.48
2 alpha- and beta-secretase: profound changes in Alzheimer's disease. Biochem Biophys Res Commun 2002 1.37
3 Treatment of murine osteoarthritis with TrkAd5 reveals a pivotal role for nerve growth factor in non-inflammatory joint pain. Pain 2010 1.37
4 Targeting nerve growth factor in pain: what is the therapeutic potential? BioDrugs 2008 1.26
5 Biological activity of nerve growth factor precursor is dependent upon relative levels of its receptors. J Biol Chem 2009 1.21
6 Brain-derived neurotrophic factor drives the changes in excitatory synaptic transmission in the rat superficial dorsal horn that follow sciatic nerve injury. J Physiol 2009 1.19
7 Premorbid effects of APOE on synaptic proteins in human temporal neocortex. Neurobiol Aging 2005 1.13
8 Decrease in bladder overactivity with REN1820 in rats with cyclophosphamide induced cystitis. J Urol 2005 1.10
9 Human ProNGF: biological effects and binding profiles at TrkA, P75NTR and sortilin. J Neurochem 2008 1.05
10 Measurement of pre- and post-synaptic proteins in cerebral cortex: effects of post-mortem delay. J Neurosci Methods 2004 1.04
11 The neurotrophins and their role in Alzheimer's disease. Curr Neuropharmacol 2011 0.98
12 Pulmonary distribution, regulation, and functional role of Trk receptors in a murine model of asthma. J Allergy Clin Immunol 2006 0.94
13 Neurotrophin-3 is a novel angiogenic factor capable of therapeutic neovascularization in a mouse model of limb ischemia. Arterioscler Thromb Vasc Biol 2010 0.88
14 TrkAd5: A novel therapeutic agent for treatment of inflammatory pain and asthma. J Pharmacol Exp Ther 2005 0.84
15 A discrete domain of the human TrkB receptor defines the binding sites for BDNF and NT-4. Biochem Biophys Res Commun 2002 0.82
16 Familial Alzheimer's disease presenilin 1 mutation M146V increases gamma secretase cutting of p75NTR in vitro. Brain Res 2007 0.77
17 Design and nuclear magnetic resonance (NMR) structure determination of the second extracellular immunoglobulin tyrosine kinase A (TrkAIg2) domain construct for binding site elucidation in drug discovery. J Med Chem 2014 0.75