Ian J Jacobs

Author PubWeight™ 84.29‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Age-dependent DNA methylation of genes that are suppressed in stem cells is a hallmark of cancer. Genome Res 2010 6.03
2 Three biomarkers identified from serum proteomic analysis for the detection of early stage ovarian cancer. Cancer Res 2004 5.68
3 A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2. Nat Genet 2009 4.38
4 An epigenetic signature in peripheral blood predicts active ovarian cancer. PLoS One 2009 3.33
5 Prospective study using the risk of ovarian cancer algorithm to screen for ovarian cancer. J Clin Oncol 2005 3.15
6 Calculation of the risk of ovarian cancer from serial CA-125 values for preclinical detection in postmenopausal women. J Clin Oncol 2003 2.58
7 CA125 expression pattern, prognosis and correlation with serum CA125 in ovarian tumor patients. From The Danish "MALOVA" Ovarian Cancer Study. Gynecol Oncol 2006 2.47
8 Preoperative sensitivity and specificity for early-stage ovarian cancer when combining cancer antigen CA-125II, CA 15-3, CA 72-4, and macrophage colony-stimulating factor using mixtures of multivariate normal distributions. J Clin Oncol 2004 2.32
9 Results of annual screening in phase I of the United Kingdom familial ovarian cancer screening study highlight the need for strict adherence to screening schedule. J Clin Oncol 2012 1.90
10 The sex hormone system in carriers of BRCA1/2 mutations: a case-control study. Lancet Oncol 2013 1.83
11 Epigenotyping in peripheral blood cell DNA and breast cancer risk: a proof of principle study. PLoS One 2008 1.75
12 HOXA11 DNA methylation--a novel prognostic biomarker in ovarian cancer. Int J Cancer 2008 1.44
13 Performance of ultrasound as a second line test to serum CA125 in ovarian cancer screening. BJOG 2014 1.43
14 Association between invasive ovarian cancer susceptibility and 11 best candidate SNPs from breast cancer genome-wide association study. Hum Mol Genet 2009 1.42
15 Expression of vascular endothelial growth factor (VEGF)-C and VEGF-D, and their receptor VEGFR-3, during different stages of cervical carcinogenesis. J Pathol 2003 1.39
16 Prognostic value of estrogen receptor and progesterone receptor tumor expression in Danish ovarian cancer patients: from the 'MALOVA' ovarian cancer study. Oncol Rep 2007 1.34
17 The dynamics and prognostic potential of DNA methylation changes at stem cell gene loci in women's cancer. PLoS Genet 2012 1.33
18 Senescent fibroblasts promote neoplastic transformation of partially transformed ovarian epithelial cells in a three-dimensional model of early stage ovarian cancer. Neoplasia 2010 1.33
19 Contribution of BRCA1 and BRCA2 mutations to inherited ovarian cancer. Hum Mutat 2007 1.33
20 Significance of PTEN alterations in endometrial carcinoma: a population-based study of mutations, promoter methylation and PTEN protein expression. Int J Oncol 2004 1.31
21 A modified medium that significantly improves the growth of human normal ovarian surface epithelial (OSE) cells in vitro. Lab Invest 2004 1.31
22 The clonal evolution of metastases from primary serous epithelial ovarian cancers. Int J Cancer 2009 1.29
23 Combining multiple serum tumor markers improves detection of stage I epithelial ovarian cancer. Gynecol Oncol 2007 1.26
24 Diagnostic performance of nanoparticle-enhanced magnetic resonance imaging in the diagnosis of lymph node metastases in patients with endometrial and cervical cancer. J Clin Oncol 2005 1.22
25 BRCA1 and BRCA2 mutation prevalence and clinical characteristics of a population-based series of ovarian cancer cases from Denmark. Clin Cancer Res 2008 1.20
26 Recruitment of newly diagnosed ovarian cancer patients proved challenging in a multicentre biobanking study. J Clin Epidemiol 2010 1.18
27 STK15 polymorphisms and association with risk of invasive ovarian cancer. Cancer Epidemiol Biomarkers Prev 2004 1.18
28 Common alleles in candidate susceptibility genes associated with risk and development of epithelial ovarian cancer. Int J Cancer 2011 1.17
29 Characterization of adnexal mass lesions on MR imaging. AJR Am J Roentgenol 2003 1.16
30 Role of DNA methylation and epigenetic silencing of HAND2 in endometrial cancer development. PLoS Med 2013 1.10
31 Tagging single nucleotide polymorphisms in the BRIP1 gene and susceptibility to breast and ovarian cancer. PLoS One 2007 1.08
32 DNA methylation analysis in liquid-based cytology for cervical cancer screening. Int J Cancer 2009 1.04
33 Chromosomes 6 and 18 induce neoplastic suppression in epithelial ovarian cancer cells. Int J Cancer 2009 1.02
34 Common variants in RB1 gene and risk of invasive ovarian cancer. Cancer Res 2006 1.01
35 A molecular genetic and statistical approach for the diagnosis of dual-site cancers. J Natl Cancer Inst 2004 1.00
36 A Perl toolkit for LIMS development. Source Code Biol Med 2008 1.00
37 Distribution of p53 expression in tissue from 774 Danish ovarian tumour patients and its prognostic significance in ovarian carcinomas. APMIS 2008 0.99
38 Microcell-mediated chromosome transfer identifies EPB41L3 as a functional suppressor of epithelial ovarian cancers. Neoplasia 2010 0.99
39 HOXA methylation in normal endometrium from premenopausal women is associated with the presence of ovarian cancer: a proof of principle study. Int J Cancer 2009 0.97
40 Ovarian cancer familial relative risks by tumour subtypes and by known ovarian cancer genetic susceptibility variants. J Med Genet 2013 0.95
41 Expression level of Wilms tumor 1 (WT1) protein has limited prognostic value in epithelial ovarian cancer: from the Danish "MALOVA" ovarian cancer study. Gynecol Oncol 2007 0.94
42 Modelling genetic and clinical heterogeneity in epithelial ovarian cancers. Carcinogenesis 2011 0.93
43 MSI-low, a real phenomenon which varies in frequency among cancer types. J Pathol 2003 0.91
44 Screening for ovarian cancer. Clin Obstet Gynecol 2006 0.90
45 MR imaging of carcinoma of the vulva. AJR Am J Roentgenol 2002 0.90
46 Loss of hMSH2 and hMSH6 expression is frequent in sporadic endometrial carcinomas with microsatellite instability: a population-based study. Clin Cancer Res 2002 0.89
47 Low frequency of BRAF and CDKN2A mutations in endometrial cancer. Int J Cancer 2005 0.89
48 In vitro three-dimensional modeling of fallopian tube secretory epithelial cells. BMC Cell Biol 2013 0.87
49 Molecular evidence of a common clonal origin and subsequent divergent clonal evolution in vulval intraepithelial neoplasia, vulval squamous cell carcinoma and lymph node metastases. Int J Cancer 2002 0.85
50 A suite of Perl modules for handling microarray data. Bioinformatics 2008 0.85
51 Protein expression levels of carcinoembryonic antigen (CEA) in Danish ovarian cancer patients: from the Danish 'MALOVA'ovarian cancer study. Pathology 2008 0.84
52 Predicting clinical outcome in patients diagnosed with synchronous ovarian and endometrial cancer. Clin Cancer Res 2008 0.82
53 Clinical value of immunohistochemically detected lymphovascular space invasion in early stage cervical carcinoma. Ann Surg Oncol 2008 0.81
54 OSPACS: Ultrasound image management system. Source Code Biol Med 2008 0.81
55 Screening for the BRCA1-ins6kbEx13 mutation: potential for misdiagnosis. Mutation in brief #964. Online. Hum Mutat 2007 0.81
56 Loss of heterozygosity on the X chromosome is an independent prognostic factor in ovarian carcinoma: from the Danish "MALOVA" Ovarian Carcinoma Study. Cancer 2004 0.80
57 Molecular assessment of depth of myometrial invasion in stage I endometrial cancer: a model based on K-ras mutation analysis. Gynecol Oncol 2003 0.79
58 Distribution of microsatellite instability in Danish ovarian tumor patients and the prognostic value in ovarian cancer patients. Oncol Res 2008 0.78
59 Ovarian cancer screening. Hosp Med 2002 0.76
60 10th Biennial Helene Harris Memorial Trust meeting. Cancer Res 2006 0.75