Common alleles in candidate susceptibility genes associated with risk and development of epithelial ovarian cancer.

PubWeight™: 1.17‹?› | Rank: Top 10%

🔗 View Article (PMC 3098608)

Published in Int J Cancer on May 01, 2011

Authors

Maria Notaridou1, Lydia Quaye, Dimitra Dafou, Chris Jones, Honglin Song, Estrid Høgdall, Susanne K Kjaer, Lise Christensen, Claus Høgdall, Jan Blaakaer, Valerie McGuire, Anna H Wu, David J Van Den Berg, Malcolm C Pike, Aleksandra Gentry-Maharaj, Eva Wozniak, Tanya Sher, Ian J Jacobs, Jonathan Tyrer, Joellen M Schildkraut, Patricia G Moorman, Edwin S Iversen, Anna Jakubowska, Krzysztof Mędrek, Jan Lubiński, Roberta B Ness, Kirsten B Moysich, Galina Lurie, Lynne R Wilkens, Michael E Carney, Shan Wang-Gohrke, Jennifer A Doherty, Mary Anne Rossing, Matthias W Beckmann, Falk C Thiel, Arif B Ekici, Xiaoqing Chen, Jonathan Beesley, Australian Ovarian Cancer Study Group/Australian Cancer Study (Ovarian Cancer), Jacek Gronwald, Peter A Fasching, Jenny Chang-Claude, Marc T Goodman, Georgia Chenevix-Trench, Andrew Berchuck, C Leigh Pearce, Alice S Whittemore, Usha Menon, Paul D P Pharoah, Simon A Gayther, Susan J Ramus, Ovarian Cancer Association Consortium

Author Affiliations

1: Gynaecological Oncology Unit, UCL EGA Institute for Women's Health, University College London, United Kingdom.

Articles citing this

Whole-exome sequencing combined with functional genomics reveals novel candidate driver cancer genes in endometrial cancer. Genome Res (2012) 2.27

Mutant cohesin in premature ovarian failure. N Engl J Med (2014) 1.20

Primary culture and immortalization of human fallopian tube secretory epithelial cells. Nat Protoc (2012) 1.03

Wnt and hedgehog gene pathway expression in serous ovarian cancer. Int J Gynecol Cancer (2011) 1.02

Genetic variants in TGF-β pathway are associated with ovarian cancer risk. PLoS One (2011) 1.01

Downregulation of Filamin A interacting protein 1-like is associated with promoter methylation and induces an invasive phenotype in ovarian cancer. Mol Cancer Res (2011) 1.00

Filamin A interacting protein 1-like inhibits WNT signaling and MMP expression to suppress cancer cell invasion and metastasis. Int J Cancer (2014) 0.98

The new face of ovarian cancer modeling: better prospects for detection and treatment. F1000 Med Rep (2011) 0.94

Meiosis-specific cohesin component, Stag3 is essential for maintaining centromere chromatid cohesion, and required for DNA repair and synapsis between homologous chromosomes. PLoS Genet (2014) 0.92

Down-regulation of Filamin A interacting protein 1-like Is associated with promoter methylation and an invasive phenotype in breast, colon, lung and pancreatic cancers [corrected]. PLoS One (2013) 0.90

An analysis of polymorphisms within the Wnt signaling pathway in relation to ovarian cancer risk in a Polish population. Mol Diagn Ther (2014) 0.88

A new spontaneously transformed syngeneic model of high-grade serous ovarian cancer with a tumor-initiating cell population. Front Oncol (2014) 0.86

Insights from studies with oral cleft genes suggest associations between WNT-pathway genes and risk of oral cancer. J Dent Res (2011) 0.85

Expression and functional roles of caspase-5 in inflammatory responses of human retinal pigment epithelial cells. Invest Ophthalmol Vis Sci (2011) 0.85

Genetic, morphometric, and behavioral factors linked to the midsagittal area of the corpus callosum. Front Genet (2012) 0.84

Identification of biomarkers for esophageal squamous cell carcinoma using feature selection and decision tree methods. ScientificWorldJournal (2013) 0.80

Alcohol Consumption Modulates Host Defense in Rhesus Macaques by Altering Gene Expression in Circulating Leukocytes. J Immunol (2015) 0.80

A Single Nucleotide Polymorphism in Catalase Is Strongly Associated with Ovarian Cancer Survival. PLoS One (2015) 0.76

Polymorphisms in the p63 and p73 genes are associated with ovarian cancer risk and clinicopathological variables. J Exp Clin Cancer Res (2012) 0.75

Replication of somatic micronuclei in bovine enucleated oocytes. Cell Div (2012) 0.75

RGC32 induces epithelial-mesenchymal transition by activating the Smad/Sip1 signaling pathway in CRC. Sci Rep (2017) 0.75

Articles cited by this

Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics (2004) 125.23

The structure of haplotype blocks in the human genome. Science (2002) 50.88

Efficiency and power in genetic association studies. Nat Genet (2005) 25.56

Polygenic susceptibility to breast cancer and implications for prevention. Nat Genet (2002) 8.89

Testing association of statistically inferred haplotypes with discrete and continuous traits in samples of unrelated individuals. Hum Hered (2002) 8.64

Choosing haplotype-tagging SNPS based on unphased genotype data using a preliminary sample of unrelated subjects with an example from the Multiethnic Cohort Study. Hum Hered (2003) 5.78

A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2. Nat Genet (2009) 4.38

Recent developments in genomewide association scans: a workshop summary and review. Am J Hum Genet (2005) 3.76

Quantitative trait Loci analysis using the false discovery rate. Genetics (2005) 3.69

Chromatid cohesion defects may underlie chromosome instability in human colorectal cancers. Proc Natl Acad Sci U S A (2008) 3.52

Genome-wide association studies in cancer. Hum Mol Genet (2008) 3.34

Allele-specific amplification in cancer revealed by SNP array analysis. PLoS Comput Biol (2005) 2.84

Pathology of ovarian cancers in BRCA1 and BRCA2 carriers. Clin Cancer Res (2004) 2.17

Tagging single nucleotide polymorphisms in cell cycle control genes and susceptibility to invasive epithelial ovarian cancer. Cancer Res (2007) 1.92

Characterization of four novel epithelial ovarian cancer cell lines. In Vitro Cell Dev Biol Anim (2000) 1.91

Consortium analysis of 7 candidate SNPs for ovarian cancer. Int J Cancer (2008) 1.82

Semiautomated assessment of loss of heterozygosity and replication error in tumors. Cancer Res (1996) 1.77

Mammalian STAG3 is a cohesin specific to sister chromatid arms in meiosis I. Nat Cell Biol (2001) 1.75

Risk prediction models for familial breast cancer. Future Oncol (2006) 1.68

STAG3, a novel gene encoding a protein involved in meiotic chromosome pairing and location of STAG3-related genes flanking the Williams-Beuren syndrome deletion. FASEB J (2000) 1.65

Genetic intra-tumour heterogeneity in epithelial ovarian cancer and its implications for molecular diagnosis of tumours. J Pathol (2007) 1.61

Differentiation of human embryonal carcinomas in vitro and in vivo reveals expression profiles relevant to normal development. Cancer Res (2005) 1.52

The contribution of germline BRCA1 and BRCA2 mutations to familial ovarian cancer: no evidence for other ovarian cancer-susceptibility genes. Am J Hum Genet (1999) 1.45

Contribution of BRCA1 mutations to ovarian cancer. N Engl J Med (1997) 1.44

Progesterone receptor variation and risk of ovarian cancer is limited to the invasive endometrioid subtype: results from the Ovarian Cancer Association Consortium pooled analysis. Br J Cancer (2008) 1.38

Common variants in mismatch repair genes and risk of invasive ovarian cancer. Carcinogenesis (2006) 1.35

Role of genetic polymorphisms and ovarian cancer susceptibility. Mol Oncol (2009) 1.33

Genome-wide association studies: past, present and future. Hum Mol Genet (2008) 1.31

Mouse embryonic stem cells form follicle-like ovarian structures but do not progress through meiosis. Stem Cells (2006) 1.21

Tagging single-nucleotide polymorphisms in candidate oncogenes and susceptibility to ovarian cancer. Br J Cancer (2009) 1.08

Tagging single nucleotide polymorphisms in the BRIP1 gene and susceptibility to breast and ovarian cancer. PLoS One (2007) 1.08

Upregulation of meiosis-specific genes in lymphoma cell lines following genotoxic insult and induction of mitotic catastrophe. BMC Cancer (2006) 1.05

Clarifying the PROGINS allele association in ovarian and breast cancer risk: a haplotype-based analysis. J Natl Cancer Inst (2005) 1.05

Chromosomes 6 and 18 induce neoplastic suppression in epithelial ovarian cancer cells. Int J Cancer (2009) 1.02

Common variants in RB1 gene and risk of invasive ovarian cancer. Cancer Res (2006) 1.01

Identification of a novel tumor suppressor gene p34 on human chromosome 6q25.1. Cancer Res (2007) 0.98

Functional complementation studies identify candidate genes and common genetic variants associated with ovarian cancer survival. Hum Mol Genet (2009) 0.94

Allele-specific loss of heterozygosity in multiple colorectal adenomas: toward an integrated molecular cytogenetic map II. Cancer Genet Cytogenet (2006) 0.94

All in the (cancer) family. Nat Genet (1993) 0.93

Allele-specific loss of heterozygosity at the DAL-1/4.1B (EPB41L3) tumor-suppressor gene locus in the absence of mutation. Genes Chromosomes Cancer (2004) 0.93

Screening for the BRCA1-ins6kbEx13 mutation: potential for misdiagnosis. Mutation in brief #964. Online. Hum Mutat (2007) 0.81

Biological significance of allele specific loss of the p53 gene in breast carcinomas. Breast Cancer Res Treat (2008) 0.80

Articles by these authors

Finding the missing heritability of complex diseases. Nature (2009) 67.95

Mutations of the BRAF gene in human cancer. Nature (2002) 65.42

Patterns of somatic mutation in human cancer genomes. Nature (2007) 38.41

Genome-wide association study identifies novel breast cancer susceptibility loci. Nature (2007) 29.23

Race, breast cancer subtypes, and survival in the Carolina Breast Cancer Study. JAMA (2006) 24.01

Oncogenic pathway signatures in human cancers as a guide to targeted therapies. Nature (2005) 19.56

Multiple regions within 8q24 independently affect risk for prostate cancer. Nat Genet (2007) 14.37

Human papillomavirus and rising oropharyngeal cancer incidence in the United States. J Clin Oncol (2011) 12.10

Admixture mapping identifies 8q24 as a prostate cancer risk locus in African-American men. Proc Natl Acad Sci U S A (2006) 10.32

Low-penetrance susceptibility to breast cancer due to CHEK2(*)1100delC in noncarriers of BRCA1 or BRCA2 mutations. Nat Genet (2002) 9.71

Definition and impact of pathologic complete response on prognosis after neoadjuvant chemotherapy in various intrinsic breast cancer subtypes. J Clin Oncol (2012) 8.74

Range of genetic mutations associated with severe non-syndromic sporadic intellectual disability: an exome sequencing study. Lancet (2012) 8.42

Lung cancer: intragenic ERBB2 kinase mutations in tumours. Nature (2004) 8.35

Large-scale genotyping identifies 41 new loci associated with breast cancer risk. Nat Genet (2013) 8.24

Common variants on chromosome 6p22.1 are associated with schizophrenia. Nature (2009) 8.12

A 9-valent HPV vaccine against infection and intraepithelial neoplasia in women. N Engl J Med (2015) 7.99

Ethnic and racial differences in the smoking-related risk of lung cancer. N Engl J Med (2006) 7.82

Sensitivity and specificity of multimodal and ultrasound screening for ovarian cancer, and stage distribution of detected cancers: results of the prevalence screen of the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS). Lancet Oncol (2009) 7.67

Genome-wide association study identifies five new breast cancer susceptibility loci. Nat Genet (2010) 7.62

Retracted Genomic signatures to guide the use of chemotherapeutics. Nat Med (2006) 7.45

A common coding variant in CASP8 is associated with breast cancer risk. Nat Genet (2007) 7.35

Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2. Nat Genet (2009) 7.30

A common genetic risk factor for colorectal and prostate cancer. Nat Genet (2007) 7.11

Epidemiology of basal-like breast cancer. Breast Cancer Res Treat (2007) 7.08

Gene expression predictors of breast cancer outcomes. Lancet (2003) 6.99

Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer. Nat Genet (2008) 6.97

Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21. Nat Genet (2008) 6.75

Protection from colorectal cancer after colonoscopy: a population-based, case-control study. Ann Intern Med (2011) 6.50

Dietary fat reduction and breast cancer outcome: interim efficacy results from the Women's Intervention Nutrition Study. J Natl Cancer Inst (2006) 6.41

Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristics. PLoS Genet (2008) 6.22

Age-dependent DNA methylation of genes that are suppressed in stem cells is a hallmark of cancer. Genome Res (2010) 6.03

Dental x-rays and risk of meningioma. Cancer (2012) 5.99

Multiple loci with different cancer specificities within the 8q24 gene desert. J Natl Cancer Inst (2008) 5.82

Choosing haplotype-tagging SNPS based on unphased genotype data using a preliminary sample of unrelated subjects with an example from the Multiethnic Cohort Study. Hum Hered (2003) 5.78

Retracted An integrated genomic-based approach to individualized treatment of patients with advanced-stage ovarian cancer. J Clin Oncol (2007) 5.77

Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas. N Engl J Med (2015) 5.71

Prediction of BRCA1 status in patients with breast cancer using estrogen receptor and basal phenotype. Clin Cancer Res (2005) 5.70

Association between endometriosis and risk of histological subtypes of ovarian cancer: a pooled analysis of case-control studies. Lancet Oncol (2012) 5.70

Three biomarkers identified from serum proteomic analysis for the detection of early stage ovarian cancer. Cancer Res (2004) 5.68

A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma. Am J Hum Genet (2009) 5.62

Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array. Nat Genet (2013) 5.58

Rethinking ovarian cancer: recommendations for improving outcomes. Nat Rev Cancer (2011) 5.28

A systematic genetic assessment of 1,433 sequence variants of unknown clinical significance in the BRCA1 and BRCA2 breast cancer-predisposition genes. Am J Hum Genet (2007) 5.17

The impact of quadrivalent human papillomavirus (HPV; types 6, 11, 16, and 18) L1 virus-like particle vaccine on infection and disease due to oncogenic nonvaccine HPV types in generally HPV-naive women aged 16-26 years. J Infect Dis (2009) 5.09

Association between CYP2D6 polymorphisms and outcomes among women with early stage breast cancer treated with tamoxifen. JAMA (2009) 5.05