Pierre Wallemacq

Author PubWeight™ 83.20‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Associations between cytomegalovirus infection and functional impairment and frailty in the BELFRAIL Cohort. J Am Geriatr Soc 2011 2.38
2 Preclinical evidence that sildenafil and vardenafil activate chloride transport in cystic fibrosis. Am J Respir Crit Care Med 2007 2.18
3 Insufficient β-lactam concentrations in the early phase of severe sepsis and septic shock. Crit Care 2010 2.11
4 The effect of CYP3A5 and MDR1 (ABCB1) polymorphisms on cyclosporine and tacrolimus dose requirements and trough blood levels in stable renal transplant patients. Pharmacogenetics 2004 2.06
5 The European Register of Specialists in Clinical Chemistry and Laboratory Medicine: guide to the Register, version 3-2010. Clin Chem Lab Med 2010 1.68
6 The impact of the assay for measuring albumin on corrected ('adjusted') calcium concentrations. Nephrol Dial Transplant 2009 1.43
7 Prolonged unconsciousness in a patient on automated peritoneal dialysis. Eur J Emerg Med 2006 1.38
8 Effect of a new functional CYP3A4 polymorphism on calcineurin inhibitors' dose requirements and trough blood levels in stable renal transplant patients. Pharmacogenomics 2011 1.27
9 Revisiting the loading dose of amikacin for patients with severe sepsis and septic shock. Crit Care 2010 1.26
10 Sirolimus and tacrolimus trough concentrations and dose requirements after kidney transplantation in relation to CYP3A5 and MDR1 polymorphisms and steroids. Transplantation 2005 1.21
11 Azithromycin reduces spontaneous and induced inflammation in DeltaF508 cystic fibrosis mice. Respir Res 2006 1.12
12 Potentiation of cyclophosphamide chemotherapy using the anti-angiogenic drug thalidomide: importance of optimal scheduling to exploit the 'normalization' window of the tumor vasculature. Cancer Lett 2006 1.11
13 Azithromycin reduces exaggerated cytokine production by M1 alveolar macrophages in cystic fibrosis. Am J Respir Cell Mol Biol 2009 1.11
14 Comparison of calibrated chromogenic anti-Xa assay and PT tests with LC-MS/MS for the therapeutic monitoring of patients treated with rivaroxaban. Thromb Haemost 2013 1.02
15 The BELFRAIL (BFC80+) study: a population-based prospective cohort study of the very elderly in Belgium. BMC Geriatr 2010 1.01
16 Validation of an ELISA-based screening assay for the detection of amphetamine, MDMA and MDA in blood and oral fluid. Forensic Sci Int 2005 1.01
17 Basic protocol for transepithelial nasal potential difference measurements. J Cyst Fibros 2004 1.01
18 The EC4 European syllabus for post-graduate training in clinical chemistry and laboratory medicine: version 4--2012. Clin Chem Lab Med 2012 0.99
19 Influence of host genetic factors on efavirenz plasma and intracellular pharmacokinetics in HIV-1-infected patients. Pharmacogenomics 2010 0.95
20 Limited sampling models and Bayesian estimation for mycophenolic acid area under the curve prediction in stable renal transplant patients co-medicated with ciclosporin or sirolimus. Clin Pharmacokinet 2009 0.94
21 A simultaneous d-optimal designed study for population pharmacokinetic analyses of mycophenolic Acid and tacrolimus early after renal transplantation. J Clin Pharmacol 2011 0.93
22 Vancomycin penetration of uninfected pleural fluid exudate after continuous or intermittent infusion. Antimicrob Agents Chemother 2003 0.93
23 An overview of monitoring and supplementation of omega 3 fatty acids in cystic fibrosis. Clin Biochem 2007 0.93
24 1199G>A and 2677G>T/A polymorphisms of ABCB1 independently affect tacrolimus concentration in hepatic tissue after liver transplantation. Pharmacogenet Genomics 2007 0.92
25 Time of drug administration, CYP3A5 and ABCB1 genotypes, and analytical method influence tacrolimus pharmacokinetics: a population pharmacokinetic study. Ther Drug Monit 2009 0.91
26 CYP3A5 and ABCB1 polymorphisms influence tacrolimus concentrations in peripheral blood mononuclear cells after renal transplantation. Pharmacogenomics 2010 0.90
27 Iodine and iron status of pregnant women in Lubumbashi, Democratic Republic of Congo. Public Health Nutr 2013 0.90
28 Hyperhomocysteinemia and venous thromboembolism: a risk factor more prevalent in the elderly and in idiopathic cases. Thromb Res 2002 0.90
29 Pharmacokinetics of a loading dose of amikacin in septic patients undergoing continuous renal replacement therapy. Int J Antimicrob Agents 2011 0.89
30 Glycosomal ABC transporters of Trypanosoma brucei: characterisation of their expression, topology and substrate specificity. Int J Parasitol 2010 0.89
31 The glomerular filtration rate estimated by new and old equations as a predictor of important outcomes in elderly patients. BMC Med 2014 0.88
32 The future of hospital laboratories. Position statement from the Royal Belgian Society of Clinical Chemistry (RBSCC). Clin Chem Lab Med 2009 0.88
33 Significance of serum immune markers in identification of global functional impairment in the oldest old: cross-sectional results from the BELFRAIL study. Age (Dordr) 2013 0.87
34 Impact of CYP3A4*22 allele on tacrolimus pharmacokinetics in early period after renal transplantation: toward updated genotype-based dosage guidelines. Ther Drug Monit 2013 0.87
35 The prevalence of cardiac dysfunction and the correlation with poor functioning among the very elderly. Int J Cardiol 2011 0.87
36 Liquid chromatography-tandem mass spectrometry or automated immunoassays: what are the future trends in therapeutic drug monitoring? Clin Chem 2012 0.87
37 Correlation of tacrolimus levels in peripheral blood mononuclear cells with histological staging of rejection after liver transplantation: preliminary results of a prospective study. Transpl Int 2011 0.87
38 Barcelona Consensus on Biomarker-Based Immunosuppressive Drugs Management in Solid Organ Transplantation. Ther Drug Monit 2016 0.86
39 Immunomodulatory activity of vardenafil on induced lung inflammation in cystic fibrosis mice. J Cyst Fibros 2012 0.86
40 Monitoring of urea and potassium by reverse iontophoresis in vitro. Pharm Res 2007 0.85
41 Dysregulated proinflammatory and fibrogenic phenotype of fibroblasts in cystic fibrosis. PLoS One 2013 0.85
42 Performance of serum cystatin-C versus serum creatinine in subjects with type 1 diabetes. Diabetes Care 2003 0.85
43 Automated serum protein electrophoresis by Capillarys. Clin Chem Lab Med 2003 0.84
44 The influence of genetic polymorphisms of cytochrome P450 3A5 and ABCB1 on starting dose- and weight-standardized tacrolimus trough concentrations after kidney transplantation in relation to renal function. Clin Chem Lab Med 2006 0.84
45 Azithromycin fails to reduce increased expression of neutrophil-related cytokines in primary-cultured epithelial cells from cystic fibrosis mice. J Cyst Fibros 2009 0.84
46 Endoxifen levels and its association with CYP2D6 genotype and phenotype: evaluation of a southern Brazilian population under tamoxifen pharmacotherapy. Ther Drug Monit 2012 0.84
47 Airway delivery of low-dose miglustat normalizes nasal potential difference in F508del cystic fibrosis mice. Am J Respir Crit Care Med 2009 0.84
48 Influence of donor-recipient CYP3A4/5 genotypes, age and fluconazole on tacrolimus pharmacokinetics in pediatric liver transplantation: a population approach. Pharmacogenomics 2014 0.83
49 Biotransformation enzymes and drug transporters pharmacogenetics in relation to immunosuppressive drugs: impact on pharmacokinetics and clinical outcome. Transplantation 2008 0.83
50 Increased tissue arachidonic acid and reduced linoleic acid in a mouse model of cystic fibrosis are reversed by supplemental glycerophospholipids enriched in docosahexaenoic acid. J Nutr 2009 0.82
51 Mass spectrometry in laboratory medicine: When "high-tech" meets routine needs. Clin Biochem 2010 0.82
52 Liquid chromatography-tandem mass spectrometry method for the simultaneous analysis of multiple hallucinogens, chlorpheniramine, ketamine, ritalinic acid, and metabolites, in urine. J Anal Toxicol 2007 0.82
53 Cocaine induces a mixed lysosomal lipidosis in cultured fibroblasts, by inactivation of acid sphingomyelinase and inhibition of phospholipase A1. Toxicol Appl Pharmacol 2004 0.81
54 Influence of pancreatic status and sex on polyunsaturated fatty acid profiles in cystic fibrosis. Clin Chem 2007 0.81
55 Evaluation of a new Sebia kit for analysis of hemoglobin fractions and variants on the Capillarys system. Clin Chem Lab Med 2006 0.81
56 Airway ion transport impacts on disease presentation and severity in cystic fibrosis. Clin Biochem 2008 0.81
57 Permeability of gloves to selected chemotherapeutic agents after treatment with alcohol or isopropyl alcohol. Am J Health Syst Pharm 2012 0.81
58 Evaluation of peritoneal transport properties at onset of peritoneal dialysis and longitudinal follow-up. Nephrol Dial Transplant 2005 0.81
59 Stearoyl-CoA desaturase is an essential enzyme for the parasitic protist Trypanosoma brucei. Biochem Biophys Res Commun 2011 0.81
60 Genetic and chemical evaluation of Trypanosoma brucei oleate desaturase as a candidate drug target. PLoS One 2010 0.80
61 Fomepizole alone for severe infant ethylene glycol poisoning. Pediatr Crit Care Med 2004 0.80
62 The prevalence and detection of chronic kidney disease (CKD)-related metabolic complications as a function of estimated glomerular filtration rate in the oldest old. Arch Gerontol Geriatr 2012 0.80
63 Tacrolimus monotherapy in liver transplantation: one-year results of a prospective, randomized, double-blind, placebo-controlled study. Ann Surg 2008 0.79
64 High prevalence of thyroid dysfunction among pregnant women in Lubumbashi, Democratic Republic of Congo. Thyroid 2013 0.79
65 Interleukin-6 predicts short-term global functional decline in the oldest old: results from the BELFRAIL study. Age (Dordr) 2014 0.79
66 A fast ultra-performance liquid chromatography method for simultaneous quantification of mycophenolic acid and its phenol- and acyl-glucuronides in human plasma. Ther Drug Monit 2009 0.79
67 Modified method to measure nasal potential difference. Clin Chem Lab Med 2003 0.79
68 Association between ABCC2 polymorphism and lopinavir accumulation in peripheral blood mononuclear cells of HIV-infected patients. Pharmacogenomics 2009 0.79
69 Electrocardiographic changes with segmental akinesia after chloral hydrate overdose. J Emerg Med 2006 0.79
70 Therapeutic Drug Monitoring of Everolimus: A Consensus Report. Ther Drug Monit 2016 0.79
71 Long-term medical complications and quality of life in adult recipients surviving 10 years or more after liver transplantation. Acta Gastroenterol Belg 2005 0.78
72 Drug prescriptions unadapted to the renal function in patients aged 80 years and older. Eur J Gen Pract 2013 0.78
73 Alfentanil-induced miosis as a surrogate measure of alfentanil pharmacokinetics in patients with mild and moderate liver cirrhosis. Clin Pharmacokinet 2007 0.78
74 Alfentanil-induced miosis clearance as a liver CYP3A4 and 3A5 activity measure in healthy volunteers: improvement of experimental conditions. J Clin Pharmacol 2005 0.78
75 Value of adding natriuretic peptides and electrocardiographic findings to assess the presence of cardiac dysfunction in patients ≥80 years of age. Am J Cardiol 2013 0.78
76 Therapeutic monitoring of mycophenolate mofetil in organ transplant recipients: is it necessary? Clin Pharmacokinet 2002 0.78
77 Pharmacogenetic Biomarkers Predictive of the Pharmacokinetics and Pharmacodynamics of Immunosuppressive Drugs. Ther Drug Monit 2016 0.77
78 Impact of Laboratory Practices on Interlaboratory Variability in Therapeutic Drug Monitoring of Immunosuppressive Drugs. Ther Drug Monit 2015 0.77
79 Quantification of 8 HIV-protease inhibitors and 2 nonnucleoside reverse transcriptase inhibitors by ultra-performance liquid chromatography with diode array detection. Clin Chem 2008 0.77
80 Population pharmacokinetics of four β-lactams in critically ill septic patients comedicated with amikacin. Clin Biochem 2012 0.77
81 Efficacy and pharmacokinetics of tacrolimus oral suspension in pediatric liver transplant recipients. Pediatr Transplant 2002 0.77
82 Life-threatening dextromethorphan intoxication associated with interaction with amitriptyline in a poor CYP2D6 metabolizer: a single case re-exposure study. J Pain Symptom Manage 2008 0.77
83 CYP3A4*22 is related to increased plasma levels of 4-hydroxytamoxifen and partially compensates for reduced CYP2D6 activation of tamoxifen. Pharmacogenomics 2015 0.77
84 Estimating GFR in the oldest old: does it matter what equation we use? Age Ageing 2011 0.77
85 Prevalence of microalbuminuria and diagnostic value of dipstick proteinuria in outpatients from HIV clinics in Bukavu, the Democratic Republic of Congo. BMC Nephrol 2014 0.77
86 Lung transplantation in cystic fibrosis normalizes essential fatty acid profiles. J Cyst Fibros 2012 0.76
87 Comparison of cytochrome P4502E1 (CYP2E1) activity and hepatic and lymphocyte mRNA expression in patients with chronic hepatitis C. Toxicol Lett 2005 0.76
88 HPLC-high resolution mass spectrometry in clinical laboratory? Clin Biochem 2010 0.76
89 Influence of CYP2D6 and CYP3A4 Phenotypes, Drug Interactions, and Vitamin D Status on Tamoxifen Biotransformation. Ther Drug Monit 2015 0.75
90 Enteric hyperoxaluria in chronic pancreatitis. Medicine (Baltimore) 2017 0.75
91 Control of AA amyloidosis complicating Crohn's disease: a clinico-pathological study. Eur J Clin Invest 2013 0.75
92 Multicenter analytical evaluation of the automated electrochemiluminescence immunoassay for cyclosporine. Ther Drug Monit 2014 0.75
93 Statistical tools for dose individualization of mycophenolic acid and tacrolimus co-administered during the first month after renal transplantation. Br J Clin Pharmacol 2013 0.75
94 Population pharmacokinetic analysis of tacrolimus early after pediatric liver transplantation. Ther Drug Monit 2014 0.75
95 Assuring the Proper Analytical Performance of Measurement Procedures for Immunosuppressive Drug Concentrations in Clinical Practice: Recommendations of the International Association of Therapeutic Drug Monitoring and Clinical Toxicology Immunosuppressive Drug Scientific Committee. Ther Drug Monit 2016 0.75
96 Individually tailored immunosuppression: is there a role for biomarkers? Clin Chem 2011 0.75
97 Effervescent paracetamol poisoning: a case report. Eur J Emerg Med 2002 0.75
98 Mycophenolic acid quantification in human peripheral blood mononuclear cells using liquid chromatography-tandem mass spectrometry. Clin Biochem 2013 0.75
99 Prolonged hypotension due to deliberate trazodone overdose in the presence of fluoxetine. Ann Clin Psychiatry 2007 0.75
100 Quantification of serum free light chain kappa and lambda by the SPAPLUS analyser. Clin Biochem 2013 0.75
101 Extended release tacrolimus and antiretroviral therapy in a renal transplant recipient: so extended! Transpl Int 2010 0.75
102 Toxicokinetics of cocaine and metabolites in a body-packer becoming symptomatic. J Forensic Leg Med 2011 0.75
103 Clinically unexpected cyclosporine levels using the ACMIA method on the RXL dimension analyser. Nephrol Dial Transplant 2011 0.75
104 The ABCs of clinical biochemistry. Clin Biochem 2011 0.75