Published in Dis Model Mech on April 06, 2010
Density and function of central serotonin (5-HT) transporters, 5-HT1A and 5-HT2A receptors, and effects of their targeting on BTBR T+tf/J mouse social behavior. J Neurochem (2010) 1.24
The serotonin transporter is an exclusive client of the coat protein complex II (COPII) component SEC24C. J Biol Chem (2011) 1.11
Social defeat: impact on fear extinction and amygdala-prefrontal cortical theta synchrony in 5-HTT deficient mice. PLoS One (2011) 1.07
Stress, social behavior, and resilience: insights from rodents. Neurobiol Stress (2015) 0.96
Serotonin transporter deficient mice are vulnerable to escape deficits following inescapable shocks. Genes Brain Behav (2010) 0.94
Stress induced obesity: lessons from rodent models of stress. Front Neurosci (2013) 0.93
Differential serotonin transport is linked to the rh5-HTTLPR in peripheral blood cells. Transl Psychiatry (2012) 0.93
Targeting brain serotonin synthesis: insights into neurodevelopmental disorders with long-term outcomes related to negative emotionality, aggression and antisocial behaviour. Philos Trans R Soc Lond B Biol Sci (2012) 0.92
Individual differences in novelty-seeking behavior in rats as a model for psychosocial stress-related mood disorders. Physiol Behav (2010) 0.90
Acetaminophen differentially enhances social behavior and cortical cannabinoid levels in inbred mice. Prog Neuropsychopharmacol Biol Psychiatry (2012) 0.87
Bridging the gap between basic and applied biology: towards preclinical translation. Dis Model Mech (2013) 0.86
Differential effects of prenatal stress in 5-Htt deficient mice: towards molecular mechanisms of gene × environment interactions. PLoS One (2011) 0.85
Chronic subordination stress induces hyperphagia and disrupts eating behavior in mice modeling binge-eating-like disorder. Front Nutr (2015) 0.83
Stress-induced susceptibility to sudden cardiac death in mice with altered serotonin homeostasis. PLoS One (2012) 0.83
Early life adversity and serotonin transporter gene variation interact at the level of the adrenal gland to affect the adult hypothalamo-pituitary-adrenal axis. Transl Psychiatry (2014) 0.81
Denial of reward in the neonate shapes sociability and serotonergic activity in the adult rat. PLoS One (2012) 0.81
Top-Down Control of Serotonin Systems by the Prefrontal Cortex: A Path toward Restored Socioemotional Function in Depression. ACS Chem Neurosci (2015) 0.81
The role of the serotonergic and GABA system in translational approaches in drug discovery for anxiety disorders. Front Pharmacol (2013) 0.80
Stress-induced activation of brown adipose tissue prevents obesity in conditions of low adaptive thermogenesis. Mol Metab (2015) 0.79
Effects of repeated adolescent stress and serotonin transporter gene partial knockout in mice on behaviors and brain structures relevant to major depression. Front Behav Neurosci (2013) 0.78
Mice with compromised 5-HTT function lack phosphotyrosine-mediated inhibitory control over prefrontal 5-HT responses. J Neurosci (2014) 0.78
5-HTT deficiency affects neuroplasticity and increases stress sensitivity resulting in altered spatial learning performance in the Morris water maze but not in the Barnes maze. PLoS One (2013) 0.77
Tetratricopeptide repeat domain 9A modulates anxiety-like behavior in female mice. Sci Rep (2016) 0.75
Stress, overeating, and obesity: Insights from human studies and preclinical models. Neurosci Biobehav Rev (2017) 0.75
The Relationship between Personality Traits, the 5HTT Polymorphisms, and the Occurrence of Anxiety and Depressive Symptoms in Elite Athletes. PLoS One (2016) 0.75
The Serotonin Transporter and Early Life Stress: Translational Perspectives. Front Cell Neurosci (2017) 0.75
Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants. Science (2003) 16.14
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nat Genet (2013) 8.02
Long story short: the serotonin transporter in emotion regulation and social cognition. Nat Neurosci (2007) 3.66
Why public health agencies cannot depend on good laboratory practices as a criterion for selecting data: the case of bisphenol A. Environ Health Perspect (2008) 3.27
Meta-analysis of genome-wide association studies of attention-deficit/hyperactivity disorder. J Am Acad Child Adolesc Psychiatry (2010) 3.13
Genome-wide analysis of copy number variants in attention deficit hyperactivity disorder: the role of rare variants and duplications at 15q13.3. Am J Psychiatry (2012) 2.48
Suppression of conditioning to ambiguous cues by pharmacogenetic inhibition of the dentate gyrus. Nat Neurosci (2007) 2.30
Targeting the murine serotonin transporter: insights into human neurobiology. Nat Rev Neurosci (2008) 2.21
Neural hyporesponsiveness and hyperresponsiveness during immediate and delayed reward processing in adult attention-deficit/hyperactivity disorder. Biol Psychiatry (2008) 2.04
Sporadic autonomic dysregulation and death associated with excessive serotonin autoinhibition. Science (2008) 2.03
Looking on the bright side of serotonin transporter gene variation. Biol Psychiatry (2010) 1.94
Serotonin transporter: gene, genetic disorders, and pharmacogenetics. Mol Interv (2004) 1.89
Case-control genome-wide association study of attention-deficit/hyperactivity disorder. J Am Acad Child Adolesc Psychiatry (2010) 1.86
Monoamine oxidase A gene promoter variation and rearing experience influences aggressive behavior in rhesus monkeys. Biol Psychiatry (2005) 1.81
Exposure to a low dose of bisphenol A during fetal life or in adulthood alters maternal behavior in mice. Environ Health Perspect (2002) 1.64
Genome-wide copy number variation study associates metabotropic glutamate receptor gene networks with attention deficit hyperactivity disorder. Nat Genet (2011) 1.63
Nature and nurture predispose to violent behavior: serotonergic genes and adverse childhood environment. Neuropsychopharmacology (2007) 1.56
How the serotonin story is being rewritten by new gene-based discoveries principally related to SLC6A4, the serotonin transporter gene, which functions to influence all cellular serotonin systems. Neuropharmacology (2008) 1.56
The epigenome and postnatal environmental influences in psychotic disorders. Soc Psychiatry Psychiatr Epidemiol (2014) 1.51
Identification of novel peptide hormones in the human proteome by hidden Markov model screening. Genome Res (2007) 1.50
Prefrontal/accumbal catecholamine system determines motivational salience attribution to both reward- and aversion-related stimuli. Proc Natl Acad Sci U S A (2007) 1.50
Annual research review: The (epi)genetics of neurodevelopmental disorders in the era of whole-genome sequencing--unveiling the dark matter. J Child Psychol Psychiatry (2015) 1.48
Effects of developmental exposure to bisphenol A on brain and behavior in mice. Environ Res (2008) 1.47
Early trauma and increased risk for physical aggression during adulthood: the moderating role of MAOA genotype. PLoS One (2007) 1.46
The genome of the platyfish, Xiphophorus maculatus, provides insights into evolutionary adaptation and several complex traits. Nat Genet (2013) 1.42
Regional differences in extracellular dopamine and serotonin assessed by in vivo microdialysis in mice lacking dopamine and/or serotonin transporters. Neuropsychopharmacology (2004) 1.41
Mice lacking the serotonin transporter exhibit 5-HT(1A) receptor-mediated abnormalities in tests for anxiety-like behavior. Neuropsychopharmacology (2003) 1.36
Deficiency of brain 5-HT synthesis but serotonergic neuron formation in Tph2 knockout mice. J Neural Transm (Vienna) (2008) 1.36
Role of sortase-dependent pili of Bifidobacterium bifidum PRL2010 in modulating bacterium-host interactions. Proc Natl Acad Sci U S A (2013) 1.36
Dopamine beta-hydroxylase knockout mice have alterations in dopamine signaling and are hypersensitive to cocaine. Neuropsychopharmacology (2005) 1.35
Multicenter analysis of the SLC6A3/DAT1 VNTR haplotype in persistent ADHD suggests differential involvement of the gene in childhood and persistent ADHD. Neuropsychopharmacology (2009) 1.33
Identifying molecular substrates in a mouse model of the serotonin transporter x environment risk factor for anxiety and depression. Biol Psychiatry (2007) 1.32
Differential functional variability of serotonin transporter and monoamine oxidase a genes in macaque species displaying contrasting levels of aggression-related behavior. Behav Genet (2005) 1.29
Norepinephrine in the prefrontal cortex is critical for amphetamine-induced reward and mesoaccumbens dopamine release. J Neurosci (2003) 1.29
Serotonin-1A receptor gene HTR1A variation predicts interferon-induced depression in chronic hepatitis C. Gastroenterology (2007) 1.29
Systematic identification of proteins that elicit drug side effects. Mol Syst Biol (2013) 1.28
The mesoaccumbens dopamine in coping with stress. Neurosci Biobehav Rev (2011) 1.28
Neural response to reward anticipation is modulated by Gray's impulsivity. Neuroimage (2009) 1.27
Integrating neurobiological markers of depression. Arch Gen Psychiatry (2010) 1.24
Animal models of depression in dopamine, serotonin, and norepinephrine transporter knockout mice: prominent effects of dopamine transporter deletions. Behav Pharmacol (2008) 1.23
Escalated aggressive behavior: dopamine, serotonin and GABA. Eur J Pharmacol (2005) 1.23
Spatio-temporal expression of tryptophan hydroxylase isoforms in murine and human brain: convergent data from Tph2 knockout mice. Eur Neuropsychopharmacol (2009) 1.22
Altered serotonin synthesis, turnover and dynamic regulation in multiple brain regions of mice lacking the serotonin transporter. Neuropharmacology (2005) 1.20
Metabolic consequences and vulnerability to diet-induced obesity in male mice under chronic social stress. PLoS One (2009) 1.19
Developmental exposure to low-dose estrogenic endocrine disruptors alters sex differences in exploration and emotional responses in mice. Horm Behav (2007) 1.18
Toward a molecular architecture of personality. Behav Brain Res (2003) 1.18
Behavioral and physiological characterization of male mice under chronic psychosocial stress. Psychoneuroendocrinology (2004) 1.18
Alpha-Ca2+/calmodulin-dependent protein kinase II contributes to the developmental programming of anxiety in serotonin receptor 1A knock-out mice. J Neurosci (2008) 1.16
Dopamine and cognitive control: the influence of spontaneous eyeblink rate and dopamine gene polymorphisms on perseveration and distractibility. Behav Neurosci (2005) 1.15
Additive effects of serotonin transporter and tryptophan hydroxylase-2 gene variation on emotional processing. Cereb Cortex (2006) 1.14
3,4-methylenedioxymethamphetamine self-administration is abolished in serotonin transporter knockout mice. Biol Psychiatry (2007) 1.14
Tryptophan hydroxylase-2 (TPH2) in disorders of cognitive control and emotion regulation: a perspective. Psychoneuroendocrinology (2011) 1.13
Neurogenesis and schizophrenia: dividing neurons in a divided mind? Eur Arch Psychiatry Clin Neurosci (2007) 1.12
Association of the functional V158M catechol-O-methyl-transferase polymorphism with panic disorder in women. Int J Neuropsychopharmacol (2004) 1.12
Polygenic transmission and complex neuro developmental network for attention deficit hyperactivity disorder: genome-wide association study of both common and rare variants. Am J Med Genet B Neuropsychiatr Genet (2013) 1.11
High loading of polygenic risk for ADHD in children with comorbid aggression. Am J Psychiatry (2013) 1.10
Activation of TRPV1 in the VTA excites dopaminergic neurons and increases chemical- and noxious-induced dopamine release in the nucleus accumbens. Neuropsychopharmacology (2005) 1.10
Association between the HOXA1 A218G polymorphism and increased head circumference in patients with autism. Biol Psychiatry (2004) 1.10
Genome-wide association study in German patients with attention deficit/hyperactivity disorder. Am J Med Genet B Neuropsychiatr Genet (2011) 1.09
Gender-dependent modulation of brain monoamines and anxiety-like behaviors in mice with genetic serotonin transporter and BDNF deficiencies. Cell Mol Neurobiol (2006) 1.09
Transmission disequilibrium of polymorphic variants in the tryptophan hydroxylase-2 gene in children and adolescents with obsessive-compulsive disorder. Int J Neuropsychopharmacol (2005) 1.08
Principal pathogenetic components and biological endophenotypes in autism spectrum disorders. Autism Res (2010) 1.08
Serotonin uptake into dopamine neurons via dopamine transporters: a compensatory alternative. Brain Res (2002) 1.08
Chronic psychosocial stress down-regulates central cytokines mRNA. Brain Res Bull (2003) 1.08
Cross-disorder analysis of bipolar risk genes: further evidence of DGKH as a risk gene for bipolar disorder, but also unipolar depression and adult ADHD. Neuropsychopharmacology (2011) 1.07
Genes regulating the serotonin metabolic pathway in the brain stem and their role in the etiopathogenesis of the sudden infant death syndrome. Genomics (2008) 1.07
Dopamine in the medial prefrontal cortex controls genotype-dependent effects of amphetamine on mesoaccumbens dopamine release and locomotion. Neuropsychopharmacology (2004) 1.07
Regional brain activation changes and abnormal functional connectivity of the ventrolateral prefrontal cortex during working memory processing in adults with attention-deficit/hyperactivity disorder. Hum Brain Mapp (2009) 1.06
Characterization of a novel peripheral pro-lipolytic mechanism in mice: role of VGF-derived peptide TLQP-21. Biochem J (2012) 1.06
The medial prefrontal cortex determines the accumbens dopamine response to stress through the opposing influences of norepinephrine and dopamine. Cereb Cortex (2007) 1.06
Clinical, morphological, and biochemical correlates of head circumference in autism. Biol Psychiatry (2007) 1.06
Influence of functional variant of neuronal nitric oxide synthase on impulsive behaviors in humans. Arch Gen Psychiatry (2009) 1.06
Association of dopamine transporter and monoamine oxidase molecular polymorphisms with sudden infant death syndrome and stillbirth: new insights into the serotonin hypothesis. Neurogenetics (2008) 1.05
Social hedonic capacity is associated with the A118G polymorphism of the mu-opioid receptor gene (OPRM1) in adult healthy volunteers and psychiatric patients. Soc Neurosci (2010) 1.05
Absence of thermal hyperalgesia in serotonin transporter-deficient mice. J Neurosci (2003) 1.05
Susceptibility to amphetamine-induced place preference is predicted by locomotor response to novelty and amphetamine in the mouse. Psychopharmacology (Berl) (2003) 1.05
D-amphetamine-related reinforcing effects are reduced in mice exposed prenatally to estrogenic endocrine disruptors. Brain Res Bull (2004) 1.04
Chemokine fractalkine/CX3CL1 negatively modulates active glutamatergic synapses in rat hippocampal neurons. J Neurosci (2006) 1.04
Co-morbidity of adult attention-deficit/hyperactivity disorder with focus on personality traits and related disorders in a tertiary referral center. Eur Arch Psychiatry Clin Neurosci (2007) 1.04
Prefrontal cortical norepinephrine release is critical for morphine-induced reward, reinstatement and dopamine release in the nucleus accumbens. Cereb Cortex (2005) 1.03