Published in Kidney Int on April 14, 2010
Physiological insights into all-trans-retinoic acid biosynthesis. Biochim Biophys Acta (2011) 1.86
Nephric duct insertion is a crucial step in urinary tract maturation that is regulated by a Gata3-Raldh2-Ret molecular network in mice. Development (2011) 1.29
Developmental origins of chronic renal disease: an integrative hypothesis. Int J Nephrol (2013) 0.86
Evaluation of High Resolution Melting analysis as an alternate tool to screen for risk alleles associated with small kidneys in Indian newborns. BMC Nephrol (2011) 0.84
Nephron number and its determinants in early life: a primer. Pediatr Nephrol (2014) 0.81
Importance of ALDH1A enzymes in determining human testicular retinoic acid concentrations. J Lipid Res (2014) 0.79
The beneficial role of retinoids in glomerular disease. Front Med (Lausanne) (2015) 0.79
Compensatory growth of congenital solitary kidneys in pigs reflects increased nephron numbers rather than hypertrophy. PLoS One (2012) 0.77
The quest for the elusive causative SNP. Kidney Int (2010) 0.75
Perturbation of Retinoid Homeostasis Increases Malformation Risk in Embryos Exposed to Pregestational Diabetes. Diabetes (2017) 0.75
Association of BMPR1A polymorphism, but not BMP4, with kidney size in full-term newborns. Pediatr Nephrol (2012) 0.75
Developmental Origins and Nephron Endowment in Hypertension. Front Pediatr (2017) 0.75
A second generation human haplotype map of over 3.1 million SNPs. Nature (2007) 85.39
A genome-wide association study identifies novel risk loci for type 2 diabetes. Nature (2007) 35.08
Genome-wide detection and characterization of positive selection in human populations. Nature (2007) 17.27
Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma. Nature (2012) 10.99
Genome-wide association scan identifies a colorectal cancer susceptibility locus on chromosome 8q24. Nat Genet (2007) 9.88
Concept, design and implementation of a cardiovascular gene-centric 50 k SNP array for large-scale genomic association studies. PLoS One (2008) 7.16
Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer. Nat Genet (2008) 6.97
Renal and retinal effects of enalapril and losartan in type 1 diabetes. N Engl J Med (2009) 6.75
Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21. Nat Genet (2008) 6.75
Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations. Nat Genet (2009) 6.39
Lung cancer susceptibility locus at 5p15.33. Nat Genet (2008) 5.99
Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia. Nat Genet (2009) 5.43
Global patterns of cis variation in human cells revealed by high-density allelic expression analysis. Nat Genet (2009) 4.72
K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas. Acta Neuropathol (2012) 4.00
Susceptibility to leprosy is associated with PARK2 and PACRG. Nature (2004) 3.07
Germ-line DNA copy number variation frequencies in a large North American population. Hum Genet (2007) 2.94
A partition-ligation-combination-subdivision EM algorithm for haplotype inference with multiallelic markers: update of the SHEsis (http://analysis.bio-x.cn). Cell Res (2009) 2.86
Outdoor temperature, age, sex, body mass index, and diabetic status determine the prevalence, mass, and glucose-uptake activity of 18F-FDG-detected BAT in humans. J Clin Endocrinol Metab (2010) 2.83
What can exome sequencing do for you? J Med Genet (2011) 2.63
Molecular identification and functional roles of a Ca(2+)-activated K+ channel in human and mouse hearts. J Biol Chem (2003) 2.22
Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height. Am J Hum Genet (2010) 2.15
Association of vitamin D receptor genetic variants with susceptibility to asthma and atopy. Am J Respir Crit Care Med (2004) 2.08
Rare variants in the CYP27B1 gene are associated with multiple sclerosis. Ann Neurol (2011) 2.07
Genome-wide profiling using single-nucleotide polymorphism arrays identifies novel chromosomal imbalances in pediatric glioblastomas. Neuro Oncol (2009) 2.04
A predominant role for the HLA class II region in the association of the MHC region with multiple sclerosis. Nat Genet (2005) 2.03
Differential expression of small-conductance Ca2+-activated K+ channels SK1, SK2, and SK3 in mouse atrial and ventricular myocytes. Am J Physiol Heart Circ Physiol (2005) 2.03
Paired-Box genes are frequently expressed in cancer and often required for cancer cell survival. Oncogene (2003) 1.99
Genetic variants of FTO influence adiposity, insulin sensitivity, leptin levels, and resting metabolic rate in the Quebec Family Study. Diabetes (2008) 1.98
Genetic dissection of Verticillium wilt resistance mediated by tomato Ve1. Plant Physiol (2009) 1.94
Tomato immune receptor Ve1 recognizes effector of multiple fungal pathogens uncovered by genome and RNA sequencing. Proc Natl Acad Sci U S A (2012) 1.84
Genetic variants associated with myocardial infarction risk factors in over 8000 individuals from five ethnic groups: The INTERHEART Genetics Study. Circ Cardiovasc Genet (2009) 1.83
CAG expansion in the Huntington disease gene is associated with a specific and targetable predisposing haplogroup. Am J Hum Genet (2009) 1.78
Genetic analysis of 103 candidate genes for coronary artery disease and associated phenotypes in a founder population reveals a new association between endothelin-1 and high-density lipoprotein cholesterol. Am J Hum Genet (2007) 1.77
Ablation of a Ca2+-activated K+ channel (SK2 channel) results in action potential prolongation in atrial myocytes and atrial fibrillation. J Physiol (2009) 1.74
GAP production of TCM herbs in China. Planta Med (2010) 1.70
T-cell factor/β-catenin activity is suppressed in two different models of autosomal dominant polycystic kidney disease. Kidney Int (2011) 1.69
Lineage specification of parietal epithelial cells requires β-catenin/Wnt signaling. J Am Soc Nephrol (2011) 1.64
Identification of T. gondii epitopes, adjuvants, and host genetic factors that influence protection of mice and humans. Vaccine (2010) 1.61
Correction of population stratification in large multi-ethnic association studies. PLoS One (2008) 1.59
Molecular coupling of a Ca2+-activated K+ channel to L-type Ca2+ channels via alpha-actinin2. Circ Res (2006) 1.59
TNFα pathway blockade ameliorates toxic effects of FSGS plasma on podocyte cytoskeleton and β3 integrin activation. Pediatr Nephrol (2012) 1.57
Exome sequencing identifies a novel multiple sclerosis susceptibility variant in the TYK2 gene. Neurology (2012) 1.56
Mutations in SETD2 and genes affecting histone H3K36 methylation target hemispheric high-grade gliomas. Acta Neuropathol (2013) 1.54
UAP56 couples piRNA clusters to the perinuclear transposon silencing machinery. Cell (2012) 1.53
Analyses of associations with asthma in four asthma population samples from Canada and Australia. Hum Genet (2009) 1.48
NALP1 influences susceptibility to human congenital toxoplasmosis, proinflammatory cytokine response, and fate of Toxoplasma gondii-infected monocytic cells. Infect Immun (2010) 1.46
LGL1, a novel branching morphogen in developing kidney, is induced by retinoic acid. Am J Physiol Renal Physiol (2007) 1.45
SHEsisEpi, a GPU-enhanced genome-wide SNP-SNP interaction scanning algorithm, efficiently reveals the risk genetic epistasis in bipolar disorder. Cell Res (2010) 1.42
The relationship of diabetic retinopathy to preclinical diabetic glomerulopathy lesions in type 1 diabetic patients: the Renin-Angiotensin System Study. Diabetes (2005) 1.40
Rare copy number variants contribute to congenital left-sided heart disease. PLoS Genet (2012) 1.35
Responsiveness of hypercalciuria to thiazide in Dent's disease. J Am Soc Nephrol (2002) 1.25
Uncertainties in predicting rice yield by current crop models under a wide range of climatic conditions. Glob Chang Biol (2014) 1.25
A common RET variant is associated with reduced newborn kidney size and function. J Am Soc Nephrol (2008) 1.24
Receptor-like kinase SOBIR1/EVR interacts with receptor-like proteins in plant immunity against fungal infection. Proc Natl Acad Sci U S A (2013) 1.23
Genome-wide assessment of imprinted expression in human cells. Genome Biol (2011) 1.22
Identification of susceptibility genes for complex diseases using pooling-based genome-wide association scans. Hum Genet (2009) 1.20
A common variant of the PAX2 gene is associated with reduced newborn kidney size. J Am Soc Nephrol (2007) 1.14
Suppression of ureteric bud apoptosis rescues nephron endowment and adult renal function in Pax2 mutant mice. J Am Soc Nephrol (2006) 1.14
Effect of nitisinone (NTBC) treatment on the clinical course of hepatorenal tyrosinemia in Québec. Mol Genet Metab (2012) 1.13
miR-520b regulates migration of breast cancer cells by targeting hepatitis B X-interacting protein and interleukin-8. J Biol Chem (2011) 1.11
HLA class I alleles tag HLA-DRB1*1501 haplotypes for differential risk in multiple sclerosis susceptibility. Proc Natl Acad Sci U S A (2008) 1.11
[Genetic diversity evaluation of ex-situ conservation population of Phellodendron amurense detected by AFLP markers]. Zhongguo Zhong Yao Za Zhi (2008) 1.10
The effects of intracellular Ca2+ on cardiac K+ channel expression and activity: novel insights from genetically altered mice. J Physiol (2004) 1.10
MEDNIK syndrome: a novel defect of copper metabolism treatable by zinc acetate therapy. Brain (2013) 1.07
Stem cell microvesicles transfer cystinosin to human cystinotic cells and reduce cystine accumulation in vitro. PLoS One (2012) 1.07
SNP genotyping of a sclerosing rhabdomyosarcoma: reveals highly aneuploid profile and a specific MDM2/HMGA2 amplification. Hum Pathol (2009) 1.06
Snap-Through Instability of Graphene on Substrates. Nanoscale Res Lett (2009) 1.04
Berberine reduces ischemia/reperfusion-induced myocardial apoptosis via activating AMPK and PI3K-Akt signaling in diabetic rats. Apoptosis (2014) 1.01
WT1 is a modifier of the Pax2 mutant phenotype: cooperation and interaction between WT1 and Pax2. Oncogene (2003) 1.01
Morphology of the cartilaginous endplates in human intervertebral disks with ultrashort echo time MR imaging. Radiology (2012) 1.01
PlantNATsDB: a comprehensive database of plant natural antisense transcripts. Nucleic Acids Res (2011) 1.00
Evaluating the performance of commercial whole-genome marker sets for capturing common genetic variation. BMC Genomics (2007) 0.99
Kinetic analysis of mouse retinal dehydrogenase type-2 (RALDH2) for retinal substrates. Biochim Biophys Acta (2002) 0.98
Presence of a calcium-activated chloride current in mouse ventricular myocytes. Am J Physiol Heart Circ Physiol (2002) 0.97
The relation of ambulatory blood pressure and pulse rate to retinopathy in type 1 diabetes mellitus: the renin-angiotensin system study. Ophthalmology (2006) 0.96
Ureteric bud apoptosis and renal hypoplasia in transgenic PAX2-Bax fetal mice mimics the renal-coloboma syndrome. J Am Soc Nephrol (2003) 0.96
The safety and use of short-acting nifedipine in hospitalized hypertensive children. Pediatr Nephrol (2004) 0.95
A variant OSR1 allele which disturbs OSR1 mRNA expression in renal progenitor cells is associated with reduction of newborn kidney size and function. Hum Mol Genet (2011) 0.95
Genetic control of alternative splicing in the TAP2 gene: possible implication in the genetics of type 1 diabetes. Diabetes (2007) 0.95
PRKCA and multiple sclerosis: association in two independent populations. PLoS Genet (2006) 0.95
The differential transcription network between embryo and endosperm in the early developing maize seed. Plant Physiol (2013) 0.95
Somatic point mutations occurring early in development: a monozygotic twin study. J Med Genet (2013) 0.95
Targeted inactivation of EGF receptor inhibits renal collecting duct development and function. J Am Soc Nephrol (2010) 0.94
Identification of a chromosome 8p locus for early-onset coronary heart disease in a French Canadian population. Eur J Hum Genet (2007) 0.94
First NIH/Office of Rare Diseases Conference on Cystinosis: past, present, and future. Pediatr Nephrol (2005) 0.94
Mutation and biochemical analysis of patients belonging to the cblB complementation class of vitamin B12-dependent methylmalonic aciduria. Mol Genet Metab (2006) 0.94
Single rice growth period was prolonged by cultivars shifts, but yield was damaged by climate change during 1981-2009 in China, and late rice was just opposite. Glob Chang Biol (2013) 0.93
Adenovirus-delivered angiopoietin 1 accelerates the resolution of inflammation of acute endotoxic lung injury in mice. Anesth Analg (2011) 0.93
All-trans retinoic acid lowers serum retinol-binding protein 4 concentrations and increases insulin sensitivity in diabetic mice. J Nutr (2009) 0.93
Association of urokinase-type plasminogen activator with asthma and atopy. Am J Respir Crit Care Med (2007) 0.92
Structure of the MST4 in complex with MO25 provides insights into its activation mechanism. Structure (2013) 0.92
Endonucleases: tools to correct the dystrophin gene. J Gene Med (2011) 0.92
Rare CNVs and tag SNPs at 15q11.2 are associated with schizophrenia in the Han Chinese population. Schizophr Bull (2012) 0.91
Genetic diversity of the apolipoprotein E gene and diabetic nephropathy: a meta-analysis. Mol Biol Rep (2010) 0.91
PAX2 activates WNT4 expression during mammalian kidney development. J Biol Chem (2005) 0.91
SLC7A9 mutations in all three cystinuria subtypes. Kidney Int (2002) 0.90
Ginsenoside Rg1 attenuates okadaic acid induced spatial memory impairment by the GSK3β/tau signaling pathway and the Aβ formation prevention in rats. Eur J Pharmacol (2013) 0.90
Molecular characterization of novel TaNAC genes in wheat and overexpression of TaNAC2a confers drought tolerance in tobacco. Physiol Plant (2012) 0.90
Single-step rapid assembly of DNA origami nanostructures for addressable nanoscale bioreactors. J Am Chem Soc (2012) 0.89