Published in J Biol Chem on February 22, 2011
Elevation of highly up-regulated in liver cancer (HULC) by hepatitis B virus X protein promotes hepatoma cell proliferation via down-regulating p18. J Biol Chem (2012) 2.16
The oncoprotein HBXIP uses two pathways to up-regulate S100A4 in promotion of growth and migration of breast cancer cells. J Biol Chem (2012) 1.02
The oncoprotein HBXIP activates transcriptional coregulatory protein LMO4 via Sp1 to promote proliferation of breast cancer cells. Carcinogenesis (2013) 1.01
MicroRNA-520b inhibits growth of hepatoma cells by targeting MEKK2 and cyclin D1. PLoS One (2012) 0.99
Tat-activating regulatory DNA-binding protein regulates glycolysis in hepatocellular carcinoma by regulating the platelet isoform of phosphofructokinase through microRNA 520. Hepatology (2013) 0.96
Hepatitis B virus X protein accelerates hepatocarcinogenesis with partner survivin through modulating miR-520b and HBXIP. Mol Cancer (2014) 0.90
Molecular characteristics of CTA056, a novel interleukin-2-inducible T-cell kinase inhibitor that selectively targets malignant T cells and modulates oncomirs. Mol Pharmacol (2012) 0.89
Transcription of Interleukin-8: How Altered Regulation Can Affect Cystic Fibrosis Lung Disease. Biomolecules (2015) 0.88
Therapeutic microRNAs targeting the NF-kappa B signaling circuits of cancers. Adv Drug Deliv Rev (2014) 0.88
The nuclear import of oncoprotein hepatitis B X-interacting protein depends on interacting with c-Fos and phosphorylation of both proteins in breast cancer cells. J Biol Chem (2013) 0.85
C19MC microRNAs regulate the migration of human trophoblasts. Endocrinology (2014) 0.85
Computational analysis of expression of human embryonic stem cell-associated signatures in tumors. BMC Res Notes (2011) 0.81
Deacetylation of tumor-suppressor MST1 in Hippo pathway induces its degradation through HBXIP-elevated HDAC6 in promotion of breast cancer growth. Oncogene (2015) 0.81
The oncoprotein HBXIP modulates the feedback loop of MDM2/p53 to enhance the growth of breast cancer. J Biol Chem (2015) 0.79
Regulation of IL-8 gene expression in gliomas by microRNA miR-93. BMC Cancer (2015) 0.77
MiR-520b as a novel molecular target for suppressing stemness phenotype of head-neck cancer by inhibiting CD44. Sci Rep (2017) 0.75
MicroRNA Expression in Cystic Fibrosis Airway Epithelium. Biomolecules (2013) 0.75
Onco-GPCR signaling and dysregulated expression of microRNAs in human cancer. J Hum Genet (2016) 0.75
The Fragment HMGA2-sh-3p20 from HMGA2 mRNA 3'UTR Promotes the Growth of Hepatoma Cells by Upregulating HMGA2. Sci Rep (2017) 0.75
Upregulation of miR-520b promotes ovarian cancer growth. Oncol Lett (2017) 0.75
Inflammatory factor TNF-α promotes the growth of breast cancer via the positive feedback loop of TNFR1/NF-κB (and/or p38)/p-STAT3/HBXIP/TNFR1. Oncotarget (2017) 0.75
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MicroRNA-21 targets tumor suppressor genes in invasion and metastasis. Cell Res (2008) 7.53
Multiple control of interleukin-8 gene expression. J Leukoc Biol (2002) 5.35
Expression of microRNA-146 suppresses NF-kappaB activity with reduction of metastatic potential in breast cancer cells. Oncogene (2008) 4.21
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MicroRNA-21 targets a network of key tumor-suppressive pathways in glioblastoma cells. Cancer Res (2008) 3.70
Breast cancer metastasis suppressor 1 up-regulates miR-146, which suppresses breast cancer metastasis. Cancer Res (2009) 3.40
miR-29a suppresses tristetraprolin, which is a regulator of epithelial polarity and metastasis. EMBO Rep (2009) 3.03
MicroRNAs and their target gene networks in breast cancer. Breast Cancer Res (2010) 2.83
HBXIP functions as a cofactor of survivin in apoptosis suppression. EMBO J (2003) 2.47
Increased serum interleukin-8 in patients with early and metastatic breast cancer correlates with early dissemination and survival. Clin Cancer Res (2004) 2.12
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Cloning and characterization of a novel hepatitis B virus x binding protein that inhibits viral replication. J Virol (1998) 1.96
CXCL8/IL8 stimulates vascular endothelial growth factor (VEGF) expression and the autocrine activation of VEGFR2 in endothelial cells by activating NFkappaB through the CBM (Carma3/Bcl10/Malt1) complex. J Biol Chem (2008) 1.93
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NF-kappa B genes have a major role in inflammatory breast cancer. BMC Cancer (2008) 1.82
CXCL8/IL-8 and CXCL12/SDF-1alpha co-operatively promote invasiveness and angiogenesis in pancreatic cancer. Int J Cancer (2009) 1.79
NFkappaB signaling in carcinogenesis and as a potential molecular target for cancer therapy. Apoptosis (2009) 1.71
MicroRNA-183 regulates Ezrin expression in lung cancer cells. FEBS Lett (2008) 1.56
MicroRNAs regulate CYP3A4 expression via direct and indirect targeting. Drug Metab Dispos (2009) 1.55
Dachshund inhibits oncogene-induced breast cancer cellular migration and invasion through suppression of interleukin-8. Proc Natl Acad Sci U S A (2008) 1.51
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MicroRNA 132 regulates nutritional stress-induced chemokine production through repression of SirT1. Mol Endocrinol (2009) 1.41
Identification of interleukin-8 as estrogen receptor-regulated factor involved in breast cancer invasion and angiogenesis by protein arrays. Int J Cancer (2004) 1.36
ST14 (suppression of tumorigenicity 14) gene is a target for miR-27b, and the inhibitory effect of ST14 on cell growth is independent of miR-27b regulation. J Biol Chem (2009) 1.34
Cutting edge: down-regulation of MHC class I-related chain A on tumor cells by IFN-gamma-induced microRNA. J Immunol (2009) 1.30
Interleukin-8 modulates growth and invasiveness of estrogen receptor-negative breast cancer cells. Int J Cancer (2007) 1.26
Hepatitis B virus X protein upregulates survivin expression in hepatoma tissues. J Med Virol (2005) 1.24
MicroRNA-224 is upregulated in HepG2 cells and involved in cellular migration and invasion. J Gastroenterol Hepatol (2009) 1.24
Hepatitis B virus X protein promotes liver cell proliferation via a positive cascade loop involving arachidonic acid metabolism and p-ERK1/2. Cell Res (2010) 1.19
Interaction of hepatitis B viral oncoprotein with cellular target HBXIP dysregulates centrosome dynamics and mitotic spindle formation. J Biol Chem (2007) 1.08
Interleukin-8 expression is regulated by histone deacetylases through the nuclear factor-kappaB pathway in breast cancer. Mol Pharmacol (2008) 1.06
The role of the NFkappaB signalling pathway in cancer. Clin Transl Oncol (2008) 1.04
Involvement of hepatitis B X-interacting protein (HBXIP) in proliferation regulation of cells. Acta Pharmacol Sin (2007) 1.03
Estradiol increases IL-8 secretion of normal human breast tissue and breast cancer in vivo. J Immunol (2009) 1.01
miRNA-520b and miR-520e sensitize breast cancer cells to complement attack via directly targeting 3'UTR of CD46. Cancer Biol Ther (2010) 0.96
Human ATP-dependent RNA/DNA helicase hSuv3p interacts with the cofactor of survivin HBXIP. FEBS J (2005) 0.96
Acquisition of stable inducible up-regulation of nuclear factor-kappaB by tumor necrosis factor exposure confers increased radiation resistance without increased transformation in breast cancer cells. Mol Cancer Res (2008) 0.92
Tid1 negatively regulates the migratory potential of cancer cells by inhibiting the production of interleukin-8. Cancer Res (2005) 0.91
[Screening of a sub-clone of human breast cancer cells with high metastasis potential]. Zhonghua Yi Xue Za Zhi (2006) 0.89
Promotion of cell proliferation by HBXIP via upregulation of human telomerase reverse transcriptase in human mesenchymal stem cells. Acta Pharmacol Sin (2008) 0.87
The TetR family of transcriptional repressors. Microbiol Mol Biol Rev (2005) 6.02
Effect of genetic variation in the organic cation transporter 1 (OCT1) on metformin action. J Clin Invest (2007) 4.47
Graphene in mice: ultrahigh in vivo tumor uptake and efficient photothermal therapy. Nano Lett (2010) 3.59
Biological features of novel avian influenza A (H7N9) virus. Nature (2013) 3.24
Significant reduction of normal tissue dose by proton radiotherapy compared with three-dimensional conformal or intensity-modulated radiation therapy in Stage I or Stage III non-small-cell lung cancer. Int J Radiat Oncol Biol Phys (2006) 2.90
A partition-ligation-combination-subdivision EM algorithm for haplotype inference with multiallelic markers: update of the SHEsis (http://analysis.bio-x.cn). Cell Res (2009) 2.86
4D Proton treatment planning strategy for mobile lung tumors. Int J Radiat Oncol Biol Phys (2007) 2.80
Apollon ubiquitinates SMAC and caspase-9, and has an essential cytoprotection function. Nat Cell Biol (2004) 2.63
Monte Carlo simulations for configuring and testing an analytical proton dose-calculation algorithm. Phys Med Biol (2007) 2.57
Study on nanometric cutting of germanium by molecular dynamics simulation. Nanoscale Res Lett (2013) 2.48
microRNA-21 negatively regulates Cdc25A and cell cycle progression in colon cancer cells. Cancer Res (2009) 2.32
Genomic distribution of CHD7 on chromatin tracks H3K4 methylation patterns. Genome Res (2009) 2.31
Role of GSK3 beta in behavioral abnormalities induced by serotonin deficiency. Proc Natl Acad Sci U S A (2008) 2.23
Molecular identification and functional roles of a Ca(2+)-activated K+ channel in human and mouse hearts. J Biol Chem (2003) 2.22
Elevation of highly up-regulated in liver cancer (HULC) by hepatitis B virus X protein promotes hepatoma cell proliferation via down-regulating p18. J Biol Chem (2012) 2.16
Observed changes in winter wheat phenology in the North China Plain for 1981-2009. Int J Biometeorol (2012) 2.11
Reversible methylation of promoter-bound STAT3 by histone-modifying enzymes. Proc Natl Acad Sci U S A (2010) 2.06
VCIP135, a novel essential factor for p97/p47-mediated membrane fusion, is required for Golgi and ER assembly in vivo. J Cell Biol (2002) 2.06
Structural insights into the activity of enhancer-binding proteins. Science (2005) 2.04
Differential expression of small-conductance Ca2+-activated K+ channels SK1, SK2, and SK3 in mouse atrial and ventricular myocytes. Am J Physiol Heart Circ Physiol (2005) 2.03
A novel class of potent influenza virus inhibitors: polysubstituted acylthiourea and its fused heterocycle derivatives. Bioorg Med Chem Lett (2005) 2.01
The crystal structure of murine p97/VCP at 3.6A. J Struct Biol (2003) 1.98
p37 is a p97 adaptor required for Golgi and ER biogenesis in interphase and at the end of mitosis. Dev Cell (2006) 1.95
In vivo pharmacokinetics, long-term biodistribution, and toxicology of PEGylated graphene in mice. ACS Nano (2010) 1.94
Genetic dissection of Verticillium wilt resistance mediated by tomato Ve1. Plant Physiol (2009) 1.94
Proton stereotactic body radiation therapy for clinically challenging cases of centrally and superiorly located stage I non-small-cell lung cancer. Int J Radiat Oncol Biol Phys (2010) 1.90
Tomato immune receptor Ve1 recognizes effector of multiple fungal pathogens uncovered by genome and RNA sequencing. Proc Natl Acad Sci U S A (2012) 1.84
Ablation of a Ca2+-activated K+ channel (SK2 channel) results in action potential prolongation in atrial myocytes and atrial fibrillation. J Physiol (2009) 1.74
Robust optimization of intensity modulated proton therapy. Med Phys (2012) 1.72
Suppression of tumorigenesis by human mesenchymal stem cells in a hepatoma model. Cell Res (2008) 1.70
Effects of hepatitis B virus X protein on the development of liver cancer. J Lab Clin Med (2006) 1.70
GAP production of TCM herbs in China. Planta Med (2010) 1.70
RNA polymerase and transcription elongation factor Spt4/5 complex structure. Proc Natl Acad Sci U S A (2010) 1.70
T-cell factor/β-catenin activity is suppressed in two different models of autosomal dominant polycystic kidney disease. Kidney Int (2011) 1.69
Structural basis of the interaction between the AAA ATPase p97/VCP and its adaptor protein p47. EMBO J (2004) 1.68
Insights into adaptor binding to the AAA protein p97. Biochem Soc Trans (2008) 1.66
Differential expression of the RANKL/RANK/OPG system is associated with bone metastasis in human non-small cell lung cancer. PLoS One (2013) 1.64
Effectiveness of noncoplanar IMRT planning using a parallelized multiresolution beam angle optimization method for paranasal sinus carcinoma. Int J Radiat Oncol Biol Phys (2005) 1.63
Going through the motions: the ATPase cycle of p97. J Struct Biol (2006) 1.61
Molecular coupling of a Ca2+-activated K+ channel to L-type Ca2+ channels via alpha-actinin2. Circ Res (2006) 1.59
Effects of interfractional motion and anatomic changes on proton therapy dose distribution in lung cancer. Int J Radiat Oncol Biol Phys (2008) 1.56
Modus operandi of the bacterial RNA polymerase containing the sigma54 promoter-specificity factor. Mol Microbiol (2008) 1.56
Crystal structures of multidrug binding protein TtgR in complex with antibiotics and plant antimicrobials. J Mol Biol (2007) 1.55
A human ALDH1A2 gene variant is associated with increased newborn kidney size and serum retinoic acid. Kidney Int (2010) 1.55
Hadoop-GIS: A High Performance Spatial Data Warehousing System over MapReduce. Proceedings VLDB Endowment (2013) 1.55
UAP56 couples piRNA clusters to the perinuclear transposon silencing machinery. Cell (2012) 1.53
Photothermally enhanced photodynamic therapy delivered by nano-graphene oxide. ACS Nano (2011) 1.51
Use of deformed intensity distributions for on-line modification of image-guided IMRT to account for interfractional anatomic changes. Int J Radiat Oncol Biol Phys (2005) 1.49
Conformational changes in the AAA ATPase p97-p47 adaptor complex. EMBO J (2006) 1.48
Structure of the whole cytosolic region of ATP-dependent protease FtsH. Mol Cell (2006) 1.46
The ATP hydrolyzing transcription activator phage shock protein F of Escherichia coli: identifying a surface that binds sigma 54. Proc Natl Acad Sci U S A (2003) 1.45
Upregulated microRNA-29a by hepatitis B virus X protein enhances hepatoma cell migration by targeting PTEN in cell culture model. PLoS One (2011) 1.44
SHEsisEpi, a GPU-enhanced genome-wide SNP-SNP interaction scanning algorithm, efficiently reveals the risk genetic epistasis in bipolar disorder. Cell Res (2010) 1.42
Graphene based gene transfection. Nanoscale (2011) 1.40
Bacterial enhancer-binding proteins: unlocking sigma54-dependent gene transcription. Curr Opin Struct Biol (2006) 1.40
Structural basis of the nucleotide driven conformational changes in the AAA+ domain of transcription activator PspF. J Mol Biol (2006) 1.40
Organization of an activator-bound RNA polymerase holoenzyme. Mol Cell (2008) 1.39
Accelerating Pathology Image Data Cross-Comparison on CPU-GPU Hybrid Systems. Proceedings VLDB Endowment (2012) 1.39
Motions and negative cooperativity between p97 domains revealed by cryo-electron microscopy and quantised elastic deformational model. J Mol Biol (2003) 1.36
Analysis of nucleotide binding to P97 reveals the properties of a tandem AAA hexameric ATPase. J Biol Chem (2008) 1.36
Structures and organisation of AAA+ enhancer binding proteins in transcriptional activation. J Struct Biol (2006) 1.36
The influence of surface chemistry and size of nanoscale graphene oxide on photothermal therapy of cancer using ultra-low laser power. Biomaterials (2011) 1.36
Hepatitis B virus X protein modulates oncogene Yes-associated protein by CREB to promote growth of hepatoma cells. Hepatology (2012) 1.34
Optimization of surface chemistry on single-walled carbon nanotubes for in vivo photothermal ablation of tumors. Biomaterials (2011) 1.33
The role of the N-domain in the ATPase activity of the mammalian AAA ATPase p97/VCP. J Biol Chem (2012) 1.32
Identification and functional characterization of paxillin as a target of protein tyrosine phosphatase receptor T. Proc Natl Acad Sci U S A (2010) 1.30
Extramammary Paget's disease of scrotum--report of 25 cases and literature review. Urol Oncol (2008) 1.30
Structure-based mechanism of lipoteichoic acid synthesis by Staphylococcus aureus LtaS. Proc Natl Acad Sci U S A (2009) 1.30
The localization and phosphorylation of p47 are important for Golgi disassembly-assembly during the cell cycle. J Cell Biol (2003) 1.29
Controllable disorder engineering in oxygen-incorporated MoS2 ultrathin nanosheets for efficient hydrogen evolution. J Am Chem Soc (2013) 1.28
Uncertainties in predicting rice yield by current crop models under a wide range of climatic conditions. Glob Chang Biol (2014) 1.25
Hepatitis B virus X protein upregulates survivin expression in hepatoma tissues. J Med Virol (2005) 1.24
Receptor-like kinase SOBIR1/EVR interacts with receptor-like proteins in plant immunity against fungal infection. Proc Natl Acad Sci U S A (2013) 1.23
Structural insights into the p97-Ufd1-Npl4 complex. Proc Natl Acad Sci U S A (2007) 1.22
Synthetic inhibitors of cytochrome P-450 2A6: inhibitory activity, difference spectra, mechanism of inhibition, and protein cocrystallization. J Med Chem (2006) 1.20
Influence of robust optimization in intensity-modulated proton therapy with different dose delivery techniques. Med Phys (2012) 1.19
Hepatitis B virus X protein promotes liver cell proliferation via a positive cascade loop involving arachidonic acid metabolism and p-ERK1/2. Cell Res (2010) 1.19
A comprehensive comparison of IMRT and VMAT plan quality for prostate cancer treatment. Int J Radiat Oncol Biol Phys (2012) 1.19
Beyond Gaussians: a study of single-spot modeling for scanning proton dose calculation. Phys Med Biol (2012) 1.18
Mechanisms for activating bacterial RNA polymerase. FEMS Microbiol Rev (2010) 1.17
Long-circulating liposomal contrast agents for magnetic resonance imaging. Magn Reson Med (2006) 1.17
Synaptotagmin IX regulates Ca2+-dependent secretion in PC12 cells. J Biol Chem (2001) 1.17
The multidrug efflux regulator TtgV recognizes a wide range of structurally different effectors in solution and complexed with target DNA: evidence from isothermal titration calorimetry. J Biol Chem (2005) 1.16
Oxidative stress induces nuclear-to-cytosol shift of hMSH3, a potential mechanism for EMAST in colorectal cancer cells. PLoS One (2012) 1.15
Nras(G12D/+) promotes leukemogenesis by aberrantly regulating hematopoietic stem cell functions. Blood (2013) 1.15
Modeling of the role of a Bax-activation switch in the mitochondrial apoptosis decision. Biophys J (2007) 1.14
A common variant of the PAX2 gene is associated with reduced newborn kidney size. J Am Soc Nephrol (2007) 1.14
LSm14A is a processing body-associated sensor of viral nucleic acids that initiates cellular antiviral response in the early phase of viral infection. Proc Natl Acad Sci U S A (2012) 1.14
Proliferation and migration mediated by Dkk-1/Wnt/beta-catenin cascade in a model of hepatocellular carcinoma cells. Transl Res (2007) 1.14