Published in Mol Endocrinol on April 09, 2010
COUP-TFII inhibits TGF-β-induced growth barrier to promote prostate tumorigenesis. Nature (2012) 2.11
Coup d'Etat: an orphan takes control. Endocr Rev (2011) 1.45
Perturbing the cellular levels of steroid receptor coactivator-2 impairs murine endometrial function. PLoS One (2014) 1.40
Atrial identity is determined by a COUP-TFII regulatory network. Dev Cell (2013) 1.01
Estrogen receptor-α in medial amygdala neurons regulates body weight. J Clin Invest (2015) 0.93
The construction of transgenic and gene knockout/knockin mouse models of human disease. Transgenic Res (2011) 0.91
Androgen deprivation-induced NCoA2 promotes metastatic and castration-resistant prostate cancer. J Clin Invest (2014) 0.88
COUP-TFII is essential for metanephric mesenchyme formation and kidney precursor cell survival. Development (2012) 0.87
Nuclear receptor LRH-1/NR5A2 is required and targetable for liver endoplasmic reticulum stress resolution. Elife (2014) 0.86
Mig-6 suppresses endometrial cancer associated with Pten deficiency and ERK activation. Cancer Res (2014) 0.79
Choose your destiny: Make a cell fate decision with COUP-TFII. J Steroid Biochem Mol Biol (2015) 0.78
COUP-TFII regulates satellite cell function and muscular dystrophy. J Clin Invest (2016) 0.75
Endometrial Expression of Steroidogenic Factor 1 Promotes Cystic Glandular Morphogenesis. Mol Endocrinol (2016) 0.75
Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat Genet (1999) 55.63
The nuclear receptor superfamily: the second decade. Cell (1995) 24.99
Derivation of completely cell culture-derived mice from early-passage embryonic stem cells. Proc Natl Acad Sci U S A (1993) 20.33
'Green mice' as a source of ubiquitous green cells. FEBS Lett (1997) 17.06
Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice. Cell (1991) 14.89
Simple and highly efficient BAC recombineering using galK selection. Nucleic Acids Res (2005) 11.23
Disruption of overlapping transcripts in the ROSA beta geo 26 gene trap strain leads to widespread expression of beta-galactosidase in mouse embryos and hematopoietic cells. Proc Natl Acad Sci U S A (1997) 8.35
Endogenous oncogenic K-ras(G12D) stimulates proliferation and widespread neoplastic and developmental defects. Cancer Cell (2004) 8.16
AIB1, a steroid receptor coactivator amplified in breast and ovarian cancer. Science (1997) 8.05
Improved reporter strain for monitoring Cre recombinase-mediated DNA excisions in mice. Proc Natl Acad Sci U S A (1999) 6.29
Nuclear receptor expression links the circadian clock to metabolism. Cell (2006) 5.43
Role of the estrogen receptor coactivator AIB1 (SRC-3) and HER-2/neu in tamoxifen resistance in breast cancer. J Natl Cancer Inst (2003) 4.45
Mice lacking the vitamin D receptor exhibit impaired bone formation, uterine hypoplasia and growth retardation after weaning. Nat Genet (1997) 3.89
Suppression of Notch signalling by the COUP-TFII transcription factor regulates vein identity. Nature (2005) 3.67
High tumor incidence and activation of the PI3K/AKT pathway in transgenic mice define AIB1 as an oncogene. Cancer Cell (2004) 3.46
Absence of the SRC-2 coactivator results in a glycogenopathy resembling Von Gierke's disease. Science (2008) 3.17
Cre-mediated recombination in cell lineages that express the progesterone receptor. Genesis (2005) 2.67
Nuclear receptor coregulators and human disease. Endocr Rev (2007) 2.65
Chicken ovalbumin upstream promoter transcription factor (COUP-TF) dimers bind to different GGTCA response elements, allowing COUP-TF to repress hormonal induction of the vitamin D3, thyroid hormone, and retinoic acid receptors. Mol Cell Biol (1992) 2.59
Chick ovalbumin upstream promoter-transcription factors (COUP-TFs): coming of age. Endocr Rev (1997) 2.43
SRC-3 is required for prostate cancer cell proliferation and survival. Cancer Res (2005) 2.07
Function of retinoic acid receptors during embryonic development. Nucl Recept Signal (2009) 2.06
COUP-TFII is essential for radial and anteroposterior patterning of the stomach. Development (2005) 2.00
Nuclear receptors: decoding metabolic disease. FEBS Lett (2007) 1.95
Null mutation of mCOUP-TFI results in defects in morphogenesis of the glossopharyngeal ganglion, axonal projection, and arborization. Genes Dev (1997) 1.88
Generalized resistance to thyroid hormone associated with a mutation in the ligand-binding domain of the human thyroid hormone receptor beta. Proc Natl Acad Sci U S A (1989) 1.85
COUP-TFII mediates progesterone regulation of uterine implantation by controlling ER activity. PLoS Genet (2007) 1.79
Mouse lacking COUP-TFII as an animal model of Bochdalek-type congenital diaphragmatic hernia. Proc Natl Acad Sci U S A (2005) 1.65
Requirement for COUP-TFI and II in the temporal specification of neural stem cells in CNS development. Nat Neurosci (2008) 1.65
Minireview: nuclear receptors and breast cancer. Mol Endocrinol (2008) 1.58
CAR, the continuously advancing receptor, in drug metabolism and disease. Curr Drug Metab (2005) 1.46
COUP-TFII regulates tumor growth and metastasis by modulating tumor angiogenesis. Proc Natl Acad Sci U S A (2010) 1.43
The nuclear orphan receptor COUP-TFII plays an essential role in adipogenesis, glucose homeostasis, and energy metabolism. Cell Metab (2009) 1.38
In vivo analysis of progesterone receptor action in the uterus during embryo implantation. Semin Cell Dev Biol (2008) 1.34
Enrichment and efficient screening of ES cells containing a targeted mutation: the use of DT-A gene with the polyadenylation signal as a negative selection maker. Transgenic Res (1999) 1.33
Haploinsufficiency of chicken ovalbumin upstream promoter transcription factor II in female reproduction. Mol Endocrinol (2005) 1.33
COUP-TFs regulate eye development by controlling factors essential for optic vesicle morphogenesis. Development (2010) 1.23
The spectrum of mutations in UBE3A causing Angelman syndrome. Hum Mol Genet (1999) 1.21
Chicken Ovalbumin Upstream Promoter-Transcription Factor II (COUP-TFII) regulates growth and patterning of the postnatal mouse cerebellum. Dev Biol (2008) 1.18
Hereditary vitamin D resistant rickets caused by a novel mutation in the vitamin D receptor that results in decreased affinity for hormone and cellular hyporesponsiveness. J Clin Invest (1997) 1.17
NURR1 mutations in cases of schizophrenia and manic-depressive disorder. Am J Med Genet (2000) 1.16
Development of the diaphragm and genetic mouse models of diaphragmatic defects. Am J Med Genet C Semin Med Genet (2007) 1.07
Replacing the mouse androgen receptor with human alleles demonstrates glutamine tract length-dependent effects on physiology and tumorigenesis in mice. Mol Endocrinol (2006) 1.06
Nuclear receptor regulation of stemness and stem cell differentiation. Exp Mol Med (2009) 1.03
COUP-TFI controls Notch regulation of hair cell and support cell differentiation. Development (2006) 1.02
The spatial patterning of mouse cone opsin expression is regulated by bone morphogenetic protein signaling through downstream effector COUP-TF nuclear receptors. J Neurosci (2009) 1.00
Bacterial artificial chromosomes improve recombinant protein production in mammalian cells. BMC Biotechnol (2009) 0.89
Minireview: Nuclear receptors, hematopoiesis, and stem cells. Mol Endocrinol (2009) 0.87
Mutant neurogenin-3 in congenital malabsorptive diarrhea. N Engl J Med (2006) 4.31
Lineage tracing demonstrates the venous origin of the mammalian lymphatic vasculature. Genes Dev (2007) 3.81
Suppression of Notch signalling by the COUP-TFII transcription factor regulates vein identity. Nature (2005) 3.67
The SRC-3/AIB1 coactivator is degraded in a ubiquitin- and ATP-independent manner by the REGgamma proteasome. Cell (2006) 3.09
Selective phosphorylations of the SRC-3/AIB1 coactivator integrate genomic reponses to multiple cellular signaling pathways. Mol Cell (2004) 2.95
Estrogens protect pancreatic beta-cells from apoptosis and prevent insulin-deficient diabetes mellitus in mice. Proc Natl Acad Sci U S A (2006) 2.59
Regulation of SRC-3 (pCIP/ACTR/AIB-1/RAC-3/TRAM-1) Coactivator activity by I kappa B kinase. Mol Cell Biol (2002) 2.45
SRC-3Delta4 mediates the interaction of EGFR with FAK to promote cell migration. Mol Cell (2010) 2.18
Coactivator as a target gene specificity determinant for histone H3 lysine 4 methyltransferases. Proc Natl Acad Sci U S A (2006) 2.16
COUP-TFII inhibits TGF-β-induced growth barrier to promote prostate tumorigenesis. Nature (2012) 2.11
Indian hedgehog is a major mediator of progesterone signaling in the mouse uterus. Nat Genet (2006) 2.11
Bmp2 is critical for the murine uterine decidual response. Mol Cell Biol (2007) 2.09
SRC-3 is required for prostate cancer cell proliferation and survival. Cancer Res (2005) 2.07
COUP-TFII is essential for radial and anteroposterior patterning of the stomach. Development (2005) 2.00
Bone morphogenetic protein 2 functions via a conserved signaling pathway involving Wnt4 to regulate uterine decidualization in the mouse and the human. J Biol Chem (2007) 1.91
COUP-TFII mediates progesterone regulation of uterine implantation by controlling ER activity. PLoS Genet (2007) 1.79
Mutation of the androgen receptor causes oncogenic transformation of the prostate. Proc Natl Acad Sci U S A (2005) 1.73
Progesterone and glucocorticoid receptors recruit distinct coactivator complexes and promote distinct patterns of local chromatin modification. Mol Cell Biol (2003) 1.73
Phosphatidylinositol 3-kinase mediates bronchioalveolar stem cell expansion in mouse models of oncogenic K-ras-induced lung cancer. PLoS One (2008) 1.72
The transcription factor Bhlhb4 is required for rod bipolar cell maturation. Neuron (2004) 1.69
Wnt/β-catenin signaling accelerates mouse lung tumorigenesis by imposing an embryonic distal progenitor phenotype on lung epithelium. J Clin Invest (2011) 1.67
Androgen receptor represses the neuroendocrine transdifferentiation process in prostate cancer cells. Mol Endocrinol (2003) 1.66
Mouse lacking COUP-TFII as an animal model of Bochdalek-type congenital diaphragmatic hernia. Proc Natl Acad Sci U S A (2005) 1.65
Steroid receptor coactivator-3 and activator protein-1 coordinately regulate the transcription of components of the insulin-like growth factor/AKT signaling pathway. Cancer Res (2006) 1.61
BETA2/NeuroD1 null mice: a new model for transcription factor-dependent photoreceptor degeneration. J Neurosci (2003) 1.61
Identification of COUP-TFII orphan nuclear receptor as a retinoic acid-activated receptor. PLoS Biol (2008) 1.60
Pten inactivation accelerates oncogenic K-ras-initiated tumorigenesis in a mouse model of lung cancer. Cancer Res (2008) 1.58
Molecular mechanism of chicken ovalbumin upstream promoter-transcription factor (COUP-TF) actions. Keio J Med (2003) 1.55
Steroid receptor coactivator-3/AIB1 promotes cell migration and invasiveness through focal adhesion turnover and matrix metalloproteinase expression. Cancer Res (2008) 1.54
Role of the steroid receptor coactivator SRC-3 in cell growth. Mol Cell Biol (2003) 1.53
Steroid receptor coactivator 2 is critical for progesterone-dependent uterine function and mammary morphogenesis in the mouse. Mol Cell Biol (2006) 1.52
Minireview: Evolution of NURSA, the Nuclear Receptor Signaling Atlas. Mol Endocrinol (2009) 1.49
Oncogenic steroid receptor coactivator-3 is a key regulator of the white adipogenic program. Proc Natl Acad Sci U S A (2006) 1.49
Identification of an integrated SV40 T/t-antigen cancer signature in aggressive human breast, prostate, and lung carcinomas with poor prognosis. Cancer Res (2007) 1.49
Coup d'Etat: an orphan takes control. Endocr Rev (2011) 1.45
Peptidyl-prolyl isomerase 1 (Pin1) serves as a coactivator of steroid receptor by regulating the activity of phosphorylated steroid receptor coactivator 3 (SRC-3/AIB1). Mol Cell Biol (2005) 1.45
Promotion of lung carcinogenesis by chronic obstructive pulmonary disease-like airway inflammation in a K-ras-induced mouse model. Am J Respir Cell Mol Biol (2008) 1.44
COUP-TFII regulates tumor growth and metastasis by modulating tumor angiogenesis. Proc Natl Acad Sci U S A (2010) 1.43
The nuclear orphan receptor COUP-TFII is required for limb and skeletal muscle development. Mol Cell Biol (2004) 1.39
The nuclear orphan receptor COUP-TFII plays an essential role in adipogenesis, glucose homeostasis, and energy metabolism. Cell Metab (2009) 1.38
Identification of Indian hedgehog as a progesterone-responsive gene in the murine uterus. Mol Endocrinol (2002) 1.38
Deletion of the orphan nuclear receptor COUP-TFII in uterus leads to placental deficiency. Proc Natl Acad Sci U S A (2007) 1.38
International Union of Pharmacology. LXVI. Orphan nuclear receptors. Pharmacol Rev (2006) 1.38
In vivo analysis of progesterone receptor action in the uterus during embryo implantation. Semin Cell Dev Biol (2008) 1.34
COUP-TFI coordinates cortical patterning, neurogenesis, and laminar fate and modulates MAPK/ERK, AKT, and beta-catenin signaling. Cereb Cortex (2007) 1.33
Haploinsufficiency of chicken ovalbumin upstream promoter transcription factor II in female reproduction. Mol Endocrinol (2005) 1.33
Direct transcriptional regulation of neuropilin-2 by COUP-TFII modulates multiple steps in murine lymphatic vessel development. J Clin Invest (2010) 1.30
Atypical protein kinase C regulates dual pathways for degradation of the oncogenic coactivator SRC-3/AIB1. Mol Cell (2008) 1.29
Mig-6 modulates uterine steroid hormone responsiveness and exhibits altered expression in endometrial disease. Proc Natl Acad Sci U S A (2009) 1.28
SRC-3/AIB1: transcriptional coactivator in oncogenesis. Acta Pharmacol Sin (2006) 1.27
Essential phosphatases and a phospho-degron are critical for regulation of SRC-3/AIB1 coactivator function and turnover. Mol Cell (2008) 1.27
The role of BETA2/NeuroD1 in the development of the nervous system. Mol Neurobiol (2004) 1.26
Steroid receptor coactivator (SRC)-1 and SRC-3 differentially modulate tissue-specific activation functions of the progesterone receptor. Mol Endocrinol (2005) 1.25
Peroxisome proliferator-activated receptor gamma is a target of progesterone regulation in the preovulatory follicles and controls ovulation in mice. Mol Cell Biol (2008) 1.24
COUP-TFs regulate eye development by controlling factors essential for optic vesicle morphogenesis. Development (2010) 1.23
A germline mutation (A339V) in thyroid transcription factor-1 (TITF-1/NKX2.1) in patients with multinodular goiter and papillary thyroid carcinoma. J Natl Cancer Inst (2009) 1.21
Mouse models of implantation. Trends Endocrinol Metab (2007) 1.20
Neuronatin, a downstream target of BETA2/NeuroD1 in the pancreas, is involved in glucose-mediated insulin secretion. Diabetes (2005) 1.20
Partially redundant functions of SRC-1 and TIF2 in postnatal survival and male reproduction. Proc Natl Acad Sci U S A (2004) 1.19
Epithelial progesterone receptor exhibits pleiotropic roles in uterine development and function. FASEB J (2011) 1.19
Nuclear receptor COUP-TFII controls pancreatic islet tumor angiogenesis by regulating vascular endothelial growth factor/vascular endothelial growth factor receptor-2 signaling. Cancer Res (2010) 1.19
Chicken Ovalbumin Upstream Promoter-Transcription Factor II (COUP-TFII) regulates growth and patterning of the postnatal mouse cerebellum. Dev Biol (2008) 1.18
Proteomic analysis of coregulators bound to ERα on DNA and nucleosomes reveals coregulator dynamics. Mol Cell (2013) 1.17