Published in Nat Genet on September 03, 2006
Hedgehog signaling regulates epithelial-mesenchymal transition during biliary fibrosis in rodents and humans. J Clin Invest (2008) 2.89
Mechanisms of implantation: strategies for successful pregnancy. Nat Med (2012) 2.50
The antiproliferative action of progesterone in uterine epithelium is mediated by Hand2. Science (2011) 2.46
Bmp2 is critical for the murine uterine decidual response. Mol Cell Biol (2007) 2.09
Endometrial decidualization: of mice and men. Semin Reprod Med (2010) 2.01
COUP-TFII mediates progesterone regulation of uterine implantation by controlling ER activity. PLoS Genet (2007) 1.79
Uterine epithelial estrogen receptor α is dispensable for proliferation but essential for complete biological and biochemical responses. Proc Natl Acad Sci U S A (2010) 1.54
NODAL in the uterus is necessary for proper placental development and maintenance of pregnancy. Biol Reprod (2012) 1.52
Coup d'Etat: an orphan takes control. Endocr Rev (2011) 1.45
Deregulation of the serum- and glucocorticoid-inducible kinase SGK1 in the endometrium causes reproductive failure. Nat Med (2011) 1.41
Physiological and molecular determinants of embryo implantation. Mol Aspects Med (2013) 1.33
FKBP52 deficiency-conferred uterine progesterone resistance is genetic background and pregnancy stage specific. J Clin Invest (2007) 1.27
Conditional deletion of Msx homeobox genes in the uterus inhibits blastocyst implantation by altering uterine receptivity. Dev Cell (2011) 1.26
Perivascular human endometrial mesenchymal stem cells express pathways relevant to self-renewal, lineage specification, and functional phenotype. Biol Reprod (2012) 1.24
The progesterone receptor regulates implantation, decidualization, and glandular development via a complex paracrine signaling network. Mol Cell Endocrinol (2011) 1.23
Gap junction communication between uterine stromal cells plays a critical role in pregnancy-associated neovascularization and embryo survival. Development (2008) 1.22
Progesterone inhibits uterine gland development in the neonatal mouse uterus. Biol Reprod (2012) 1.21
Transforming growth factor β receptor type 1 is essential for female reproductive tract integrity and function. PLoS Genet (2011) 1.20
Epithelial progesterone receptor exhibits pleiotropic roles in uterine development and function. FASEB J (2011) 1.19
Uterine disorders and pregnancy complications: insights from mouse models. J Clin Invest (2010) 1.17
Stromal progesterone receptors mediate induction of Indian Hedgehog (IHH) in uterine epithelium and its downstream targets in uterine stroma. Endocrinology (2009) 1.14
The regulation of embryo implantation and endometrial decidualization by progesterone receptor signaling. Mol Cell Endocrinol (2011) 1.07
The Krüppel-like factor 9 (KLF9) network in HEC-1-A endometrial carcinoma cells suggests the carcinogenic potential of dys-regulated KLF9 expression. Reprod Biol Endocrinol (2008) 1.06
STAT3 regulates uterine epithelial remodeling and epithelial-stromal crosstalk during implantation. Mol Endocrinol (2013) 1.06
A mouse model to dissect progesterone signaling in the female reproductive tract and mammary gland. Genesis (2010) 1.05
Ablation of Indian hedgehog in the murine uterus results in decreased cell cycle progression, aberrant epidermal growth factor signaling, and increased estrogen signaling. Biol Reprod (2010) 1.03
Kruppel-like factor 5 (KLF5) is critical for conferring uterine receptivity to implantation. Proc Natl Acad Sci U S A (2012) 1.01
Wnt/Β-catenin and sex hormone signaling in endometrial homeostasis and cancer. Oncotarget (2010) 1.01
Temporal expression pattern of progesterone receptor in the uterine luminal epithelium suggests its requirement during early events of implantation. Fertil Steril (2011) 1.01
Global analysis of genes regulated by HOXA10 in decidualization reveals a role in cell proliferation. Mol Hum Reprod (2008) 0.99
Transient {beta}2-adrenoceptor activation confers pregnancy loss by disrupting embryo spacing at implantation. J Biol Chem (2010) 0.98
Constitutive activation of smoothened leads to female infertility and altered uterine differentiation in the mouse. Biol Reprod (2010) 0.98
Msx homeobox genes critically regulate embryo implantation by controlling paracrine signaling between uterine stroma and epithelium. PLoS Genet (2012) 0.98
Notch1 mediates uterine stromal differentiation and is critical for complete decidualization in the mouse. FASEB J (2011) 0.96
Evidence for a conserved function of heart and neural crest derivatives expressed transcript 2 in mouse and human decidualization. Reproduction (2011) 0.95
Uterine glands: development, function and experimental model systems. Mol Hum Reprod (2013) 0.94
Minireview: Steroid-regulated paracrine mechanisms controlling implantation. Mol Endocrinol (2014) 0.94
Appropriate crypt formation in the uterus for embryo homing and implantation requires Wnt5a-ROR signaling. Cell Rep (2014) 0.93
Krüppel-like factor 9 deficiency in uterine endometrial cells promotes ectopic lesion establishment associated with activated notch and hedgehog signaling in a mouse model of endometriosis. Endocrinology (2014) 0.92
Nuclear receptor coactivator-6 attenuates uterine estrogen sensitivity to permit embryo implantation. Dev Cell (2012) 0.91
Leucine and arginine regulate trophoblast motility through mTOR-dependent and independent pathways in the preimplantation mouse embryo. Dev Biol (2011) 0.90
Estrogen-regulated prohibitin is required for mouse uterine development and adult function. Endocrinology (2011) 0.89
Uterine Rbpj is required for embryonic-uterine orientation and decidual remodeling via Notch pathway-independent and -dependent mechanisms. Cell Res (2014) 0.89
Indian Hedgehog and its targets in human endometrium: menstrual cycle expression and response to CDB-2914. J Clin Endocrinol Metab (2010) 0.88
The hamster as a model for embryo implantation: insights into a multifaceted process. Semin Cell Dev Biol (2007) 0.88
Role of nuclear receptors in blastocyst implantation. Semin Cell Dev Biol (2013) 0.87
Uterine glands: biological roles in conceptus implantation, uterine receptivity and decidualization. Int J Dev Biol (2014) 0.87
Endometrial stromal beta-catenin is required for steroid-dependent mesenchymal-epithelial cross talk and decidualization. Reprod Biol Endocrinol (2012) 0.86
Unique uterine localization and regulation may differentiate LPA3 from other lysophospholipid receptors for its role in embryo implantation. Fertil Steril (2011) 0.86
Progesterone receptor signaling in the initiation of pregnancy and preservation of a healthy uterus. Int J Dev Biol (2014) 0.86
ERBB receptor feedback inhibitor 1 regulation of estrogen receptor activity is critical for uterine implantation in mice. Biol Reprod (2009) 0.85
Role of uterine stromal-epithelial crosstalk in embryo implantation. Int J Dev Biol (2014) 0.85
The molecular genetics of medulloblastoma: an assessment of new therapeutic targets. Neurosurg Rev (2008) 0.85
Biological roles of uterine glands in pregnancy. Semin Reprod Med (2014) 0.85
Sex and hedgehog: roles of genes in the hedgehog signaling pathway in mammalian sexual differentiation. Chromosome Res (2012) 0.84
Uterine activin receptor-like kinase 5 is crucial for blastocyst implantation and placental development. Proc Natl Acad Sci U S A (2015) 0.84
The transcription factor C/EBPβ is a marker of uterine receptivity and expressed at the implantation site in the primate. Reprod Sci (2010) 0.84
Dysregulation of uterine signaling pathways in progesterone receptor-Cre knockout of dicer. Mol Endocrinol (2012) 0.84
Uterine epithelial cell estrogen receptor alpha-dependent and -independent genomic profiles that underlie estrogen responses in mice. Biol Reprod (2014) 0.84
The epidermal growth factor receptor critically regulates endometrial function during early pregnancy. PLoS Genet (2014) 0.83
Uterine Epithelial Estrogen Receptor-α Controls Decidualization via a Paracrine Mechanism. Mol Endocrinol (2015) 0.83
Gene expression analysis of early stage endometrial cancers reveals unique transcripts associated with grade and histology but not depth of invasion. Front Oncol (2013) 0.83
The coregulator, repressor of estrogen receptor activity (REA), is a crucial regulator of the timing and magnitude of uterine decidualization. Endocrinology (2013) 0.83
Genes targeted by the estrogen and progesterone receptors in the human endometrial cell lines HEC1A and RL95-2. Reprod Biol Endocrinol (2009) 0.81
Progesterone-Regulated Endometrial Factors Controlling Implantation. Am J Reprod Immunol (2016) 0.80
Hedgehog signaling and steroidogenesis. Annu Rev Physiol (2015) 0.78
Endometrial Indian hedgehog expression is decreased in women with endometriosis. Fertil Steril (2011) 0.78
Expression and regulation of Foxa2 in the rat uterus during early pregnancy. J Reprod Dev (2014) 0.78
Choose your destiny: Make a cell fate decision with COUP-TFII. J Steroid Biochem Mol Biol (2015) 0.78
CRISPLD2 is a target of progesterone receptor and its expression is decreased in women with endometriosis. PLoS One (2014) 0.78
Mmu-microRNA-200a overexpression leads to implantation defect by targeting phosphatase and tensin homolog in mouse uterus. Reprod Sci (2013) 0.77
Constitutive activation of transforming growth factor Beta receptor 1 in the mouse uterus impairs uterine morphology and function. Biol Reprod (2014) 0.77
Rac1 Regulates Endometrial Secretory Function to Control Placental Development. PLoS Genet (2015) 0.76
Relative roles of the epithelial and stromal tissue compartment(s) in mediating the actions of relaxin and estrogen on cell proliferation and apoptosis in the mouse lower reproductive tract. Ann N Y Acad Sci (2009) 0.76
ARID1A Is Essential for Endometrial Function during Early Pregnancy. PLoS Genet (2015) 0.76
Impaired receptivity and decidualization in DHEA-induced PCOS mice. Sci Rep (2016) 0.76
Aberrant activation of canonical Notch1 signaling in the mouse uterus decreases progesterone receptor by hypermethylation and leads to infertility. Proc Natl Acad Sci U S A (2016) 0.76
Gain-of-function β-catenin in the uterine mesenchyme leads to impaired implantation and decidualization. J Endocrinol (2017) 0.75
In search of molecular mechanisms in endometriosis. Endocrinology (2014) 0.75
A Gata2-Dependent Transcription Network Regulates Uterine Progesterone Responsiveness and Endometrial Function. Cell Rep (2016) 0.75
Deletion of Lysophosphatidic Acid Receptor 3 (Lpar3) Disrupts Fine Local Balance of Progesterone and Estrogen Signaling in Mouse Uterus During Implantation. Biol Reprod (2015) 0.75
Endometrial Expression of Steroidogenic Factor 1 Promotes Cystic Glandular Morphogenesis. Mol Endocrinol (2016) 0.75
Mapping lineage progression of somatic progenitor cells in the mouse fetal testis. Development (2016) 0.75
cAMP-Response Element-Binding 3-Like Protein 1 (CREB3L1) is Required for Decidualization and its Expression is Decreased in Women with Endometriosis. Curr Mol Med (2016) 0.75
Mechanisms of uterine estrogen signaling during early pregnancy in mice: an update. J Mol Endocrinol (2016) 0.75
TGFβ superfamily signaling and uterine decidualization. Reprod Biol Endocrinol (2017) 0.75
p63 is the molecular switch for initiation of an epithelial stratification program. Genes Dev (2004) 6.40
Mutant neurogenin-3 in congenital malabsorptive diarrhea. N Engl J Med (2006) 4.31
Lineage tracing demonstrates the venous origin of the mammalian lymphatic vasculature. Genes Dev (2007) 3.81
Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members. Mol Cell Biol (2007) 3.73
Suppression of Notch signalling by the COUP-TFII transcription factor regulates vein identity. Nature (2005) 3.67
A Gata6-Wnt pathway required for epithelial stem cell development and airway regeneration. Nat Genet (2008) 3.37
Defective mammary gland morphogenesis in mice lacking the progesterone receptor B isoform. Proc Natl Acad Sci U S A (2003) 3.30
Homozygous ablation of fibroblast growth factor-23 results in hyperphosphatemia and impaired skeletogenesis, and reverses hypophosphatemia in Phex-deficient mice. Matrix Biol (2004) 3.23
The SRC-3/AIB1 coactivator is degraded in a ubiquitin- and ATP-independent manner by the REGgamma proteasome. Cell (2006) 3.09
Premature aging-like phenotype in fibroblast growth factor 23 null mice is a vitamin D-mediated process. FASEB J (2006) 2.99
Selective phosphorylations of the SRC-3/AIB1 coactivator integrate genomic reponses to multiple cellular signaling pathways. Mol Cell (2004) 2.95
Klotho: a novel phosphaturic substance acting as an autocrine enzyme in the renal proximal tubule. FASEB J (2010) 2.91
Activation and function of cyclin T-Cdk9 (positive transcription elongation factor-b) in cardiac muscle-cell hypertrophy. Nat Med (2002) 2.82
Cre-mediated recombination in cell lineages that express the progesterone receptor. Genesis (2005) 2.67
Estrogens protect pancreatic beta-cells from apoptosis and prevent insulin-deficient diabetes mellitus in mice. Proc Natl Acad Sci U S A (2006) 2.59
Mucin is produced by clara cells in the proximal airways of antigen-challenged mice. Am J Respir Cell Mol Biol (2004) 2.50
The antiproliferative action of progesterone in uterine epithelium is mediated by Hand2. Science (2011) 2.46
Regulation of SRC-3 (pCIP/ACTR/AIB-1/RAC-3/TRAM-1) Coactivator activity by I kappa B kinase. Mol Cell Biol (2002) 2.45
Reversal of mineral ion homeostasis and soft-tissue calcification of klotho knockout mice by deletion of vitamin D 1alpha-hydroxylase. Kidney Int (2009) 2.39
Characterization of the physical interaction of Gli proteins with SUFU proteins. J Biol Chem (2002) 2.29
PTHrP and Indian hedgehog control differentiation of growth plate chondrocytes at multiple steps. Development (2002) 2.19
SRC-3Delta4 mediates the interaction of EGFR with FAK to promote cell migration. Mol Cell (2010) 2.18
Conditional loss of uterine Pten unfailingly and rapidly induces endometrial cancer in mice. Cancer Res (2008) 2.15
Foxa2 is essential for mouse endometrial gland development and fertility. Biol Reprod (2010) 2.12
COUP-TFII inhibits TGF-β-induced growth barrier to promote prostate tumorigenesis. Nature (2012) 2.11
Bmp2 is critical for the murine uterine decidual response. Mol Cell Biol (2007) 2.09
SRC-3 is required for prostate cancer cell proliferation and survival. Cancer Res (2005) 2.07
In vivo genetic evidence for klotho-dependent, fibroblast growth factor 23 (Fgf23) -mediated regulation of systemic phosphate homeostasis. FASEB J (2008) 2.03
COUP-TFII is essential for radial and anteroposterior patterning of the stomach. Development (2005) 2.00
Conditional Kif3a ablation causes abnormal hedgehog signaling topography, growth plate dysfunction, and excessive bone and cartilage formation during mouse skeletogenesis. Development (2007) 1.97
Deletion of Dicer in somatic cells of the female reproductive tract causes sterility. Mol Endocrinol (2008) 1.91
Indian Hedgehog produced by postnatal chondrocytes is essential for maintaining a growth plate and trabecular bone. Proc Natl Acad Sci U S A (2007) 1.85
Indian hedgehog stimulates periarticular chondrocyte differentiation to regulate growth plate length independently of PTHrP. J Clin Invest (2005) 1.82
Reproductive functions of progesterone receptors. Recent Prog Horm Res (2002) 1.82
The emerging role of the fibroblast growth factor-23-klotho axis in renal regulation of phosphate homeostasis. J Endocrinol (2007) 1.81
Impaired insulin secretory capacity in mice lacking a functional vitamin D receptor. FASEB J (2003) 1.80
Liver-specific deletion of acetyl-CoA carboxylase 1 reduces hepatic triglyceride accumulation without affecting glucose homeostasis. Proc Natl Acad Sci U S A (2006) 1.79
WNT4 is a key regulator of normal postnatal uterine development and progesterone signaling during embryo implantation and decidualization in the mouse. FASEB J (2010) 1.79
COUP-TFII mediates progesterone regulation of uterine implantation by controlling ER activity. PLoS Genet (2007) 1.79
Roles of NPM2 in chromatin and nucleolar organization in oocytes and embryos. Science (2003) 1.78
Knockout of pentraxin 3, a downstream target of growth differentiation factor-9, causes female subfertility. Mol Endocrinol (2002) 1.77
Genetic ablation of vitamin D activation pathway reverses biochemical and skeletal anomalies in Fgf-23-null animals. Am J Pathol (2006) 1.75
Progesterone and glucocorticoid receptors recruit distinct coactivator complexes and promote distinct patterns of local chromatin modification. Mol Cell Biol (2003) 1.73
BMPR2 is required for postimplantation uterine function and pregnancy maintenance. J Clin Invest (2013) 1.70
The transcription factor Bhlhb4 is required for rod bipolar cell maturation. Neuron (2004) 1.69
The RANKL signaling axis is sufficient to elicit ductal side-branching and alveologenesis in the mammary gland of the virgin mouse. Dev Biol (2009) 1.67
Androgen receptor represses the neuroendocrine transdifferentiation process in prostate cancer cells. Mol Endocrinol (2003) 1.66
Mouse lacking COUP-TFII as an animal model of Bochdalek-type congenital diaphragmatic hernia. Proc Natl Acad Sci U S A (2005) 1.65
Transcriptional regulation of bcl-2 mediated by the sonic hedgehog signaling pathway through gli-1. J Biol Chem (2003) 1.65
Genetic evidence of serum phosphate-independent functions of FGF-23 on bone. PLoS Genet (2008) 1.63
A novel LacZ reporter mouse reveals complex regulation of the progesterone receptor promoter during mammary gland development. Mol Endocrinol (2002) 1.61
Steroid receptor coactivator-3 and activator protein-1 coordinately regulate the transcription of components of the insulin-like growth factor/AKT signaling pathway. Cancer Res (2006) 1.61
BETA2/NeuroD1 null mice: a new model for transcription factor-dependent photoreceptor degeneration. J Neurosci (2003) 1.61
Identification of COUP-TFII orphan nuclear receptor as a retinoic acid-activated receptor. PLoS Biol (2008) 1.60
Regulation of Gli1 transcriptional activity in the nucleus by Dyrk1. J Biol Chem (2002) 1.60
Hypervitaminosis D and premature aging: lessons learned from Fgf23 and Klotho mutant mice. Trends Mol Med (2006) 1.60
Identification of murine uterine genes regulated in a ligand-dependent manner by the progesterone receptor. Endocrinology (2005) 1.59
Hepatocyte-specific inhibition of NF-kappaB leads to apoptosis after TNF treatment, but not after partial hepatectomy. J Clin Invest (2002) 1.58
Conditional deletion of Indian hedgehog from collagen type 2alpha1-expressing cells results in abnormal endochondral bone formation. J Pathol (2005) 1.57
Ablation of vitamin D signaling rescues bone, mineral, and glucose homeostasis in Fgf-23 deficient mice. Matrix Biol (2006) 1.56
Acceleration of the glycolytic flux by steroid receptor coactivator-2 is essential for endometrial decidualization. PLoS Genet (2013) 1.56
Molecular mechanism of chicken ovalbumin upstream promoter-transcription factor (COUP-TF) actions. Keio J Med (2003) 1.55
Steroid receptor coactivator-3/AIB1 promotes cell migration and invasiveness through focal adhesion turnover and matrix metalloproteinase expression. Cancer Res (2008) 1.54
PTH ablation ameliorates the anomalies of Fgf23-deficient mice by suppressing the elevated vitamin D and calcium levels. Endocrinology (2011) 1.54
FGF-23-Klotho signaling stimulates proliferation and prevents vitamin D-induced apoptosis. J Cell Biol (2008) 1.53
Role of the steroid receptor coactivator SRC-3 in cell growth. Mol Cell Biol (2003) 1.53
NODAL in the uterus is necessary for proper placental development and maintenance of pregnancy. Biol Reprod (2012) 1.52
Steroid receptor coactivator 2 is critical for progesterone-dependent uterine function and mammary morphogenesis in the mouse. Mol Cell Biol (2006) 1.52
Animal models of implantation. Reproduction (2004) 1.49
Minireview: Evolution of NURSA, the Nuclear Receptor Signaling Atlas. Mol Endocrinol (2009) 1.49
Oncogenic steroid receptor coactivator-3 is a key regulator of the white adipogenic program. Proc Natl Acad Sci U S A (2006) 1.49
Coup d'Etat: an orphan takes control. Endocr Rev (2011) 1.45
Peptidyl-prolyl isomerase 1 (Pin1) serves as a coactivator of steroid receptor by regulating the activity of phosphorylated steroid receptor coactivator 3 (SRC-3/AIB1). Mol Cell Biol (2005) 1.45
The tumor suppressor CYLD interacts with TRIP and regulates negatively nuclear factor kappaB activation by tumor necrosis factor. J Exp Med (2003) 1.44