Yih Yean Lee

Author PubWeight™ 8.73‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Combined in silico modeling and metabolomics analysis to characterize fed-batch CHO cell culture. Biotechnol Bioeng 2012 1.17
2 Transcriptome and proteome profiling to understanding the biology of high productivity CHO cells. Mol Biotechnol 2006 1.05
3 Engineering mammalian cells in bioprocessing - current achievements and future perspectives. Biotechnol Appl Biochem 2010 0.99
4 Regulation of XBP-1 signaling during transient and stable recombinant protein production in CHO cells. Biotechnol Prog 2010 0.86
5 Transcriptional profiling of apoptotic pathways in batch and fed-batch CHO cell cultures. Biotechnol Bioeng 2006 0.80
6 2-D DIGE to expedite downstream process development for human monoclonal antibody purification. Protein Expr Purif 2009 0.80
7 Identification of cellular genes critical to recombinant protein production using a Gaussia luciferase-based siRNA screening system. J Biotechnol 2010 0.79
8 Modeling amino acid metabolism in mammalian cells-toward the development of a model library. Biotechnol Prog 2007 0.79
9 Two-dimensional fluorescence difference gel electrophoresis for comparison of affinity and non-affinity based downstream processing of recombinant monoclonal antibody. J Chromatogr A 2009 0.78
10 Heat shock protein 27 overexpression in CHO cells modulates apoptosis pathways and delays activation of caspases to improve recombinant monoclonal antibody titre in fed-batch bioreactors. Biotechnol J 2015 0.76
11 Adaptation of hybridomas to protein-free media results in a simplified two-step immunoglobulin M purification process. J Chromatogr A 2008 0.75
12 Two-dimensional difference fluorescence gel electrophoresis to verify the scale-up of a non-affinity-based downstream process for isolation of a therapeutic recombinant antibody. Electrophoresis 2010 0.75
13 Elevation of gamma-glutamyltransferase activity in 293 HEK cells constitutively expressing antisense glutaminase mRNA. Metab Eng 2005 0.75