| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Cell junction dynamics in the testis: Sertoli-germ cell interactions and male contraceptive development.
|
Physiol Rev
|
2002
|
2.60
|
|
2
|
Blood-testis barrier dynamics are regulated by testosterone and cytokines via their differential effects on the kinetics of protein endocytosis and recycling in Sertoli cells.
|
FASEB J
|
2008
|
2.13
|
|
3
|
The blood-testis barrier and its implications for male contraception.
|
Pharmacol Rev
|
2011
|
2.10
|
|
4
|
A local autocrine axis in the testes that regulates spermatogenesis.
|
Nat Rev Endocrinol
|
2010
|
2.03
|
|
5
|
Biology and regulation of ectoplasmic specialization, an atypical adherens junction type, in the testis.
|
Biochim Biophys Acta
|
2007
|
1.74
|
|
6
|
Tumor necrosis factor {alpha} reversibly disrupts the blood-testis barrier and impairs Sertoli-germ cell adhesion in the seminiferous epithelium of adult rat testes.
|
J Endocrinol
|
2006
|
1.66
|
|
7
|
TGF-beta3 and TNFalpha perturb blood-testis barrier (BTB) dynamics by accelerating the clathrin-mediated endocytosis of integral membrane proteins: a new concept of BTB regulation during spermatogenesis.
|
Dev Biol
|
2008
|
1.62
|
|
8
|
Regulation of blood-testis barrier dynamics: an in vivo study.
|
J Cell Sci
|
2004
|
1.62
|
|
9
|
Epidermal growth factor receptor pathway substrate 8 (Eps8) is a novel regulator of cell adhesion and the blood-testis barrier integrity in the seminiferous epithelium.
|
FASEB J
|
2009
|
1.61
|
|
10
|
An autocrine axis in the testis that coordinates spermiation and blood-testis barrier restructuring during spermatogenesis.
|
Proc Natl Acad Sci U S A
|
2008
|
1.55
|
|
11
|
Par3/Par6 polarity complex coordinates apical ectoplasmic specialization and blood-testis barrier restructuring during spermatogenesis.
|
Proc Natl Acad Sci U S A
|
2008
|
1.53
|
|
12
|
Disruption of Mtmr2 produces CMT4B1-like neuropathy with myelin outfolding and impaired spermatogenesis.
|
J Cell Biol
|
2004
|
1.53
|
|
13
|
Ectoplasmic specialization: a friend or a foe of spermatogenesis?
|
Bioessays
|
2007
|
1.52
|
|
14
|
Connexin 43 and plakophilin-2 as a protein complex that regulates blood-testis barrier dynamics.
|
Proc Natl Acad Sci U S A
|
2009
|
1.49
|
|
15
|
Restricted Arp3 expression in the testis prevents blood-testis barrier disruption during junction restructuring at spermatogenesis.
|
Proc Natl Acad Sci U S A
|
2010
|
1.49
|
|
16
|
Adhering junction dynamics in the testis are regulated by an interplay of beta 1-integrin and focal adhesion complex-associated proteins.
|
Endocrinology
|
2003
|
1.49
|
|
17
|
Cadmium-induced testicular injury.
|
Toxicol Appl Pharmacol
|
2009
|
1.47
|
|
18
|
Differential interactions between transforming growth factor-beta3/TbetaR1, TAB1, and CD2AP disrupt blood-testis barrier and Sertoli-germ cell adhesion.
|
J Biol Chem
|
2006
|
1.47
|
|
19
|
TGF-beta3 regulates the blood-testis barrier dynamics via the p38 mitogen activated protein (MAP) kinase pathway: an in vivo study.
|
Endocrinology
|
2003
|
1.44
|
|
20
|
Zyxin, axin, and Wiskott-Aldrich syndrome protein are adaptors that link the cadherin/catenin protein complex to the cytoskeleton at adherens junctions in the seminiferous epithelium of the rat testis.
|
J Androl
|
2004
|
1.44
|
|
21
|
Disruption of the blood-testis barrier integrity by bisphenol A in vitro: is this a suitable model for studying blood-testis barrier dynamics?
|
Int J Biochem Cell Biol
|
2009
|
1.38
|
|
22
|
Crosstalk between desmoglein-2/desmocollin-2/Src kinase and coxsackie and adenovirus receptor/ZO-1 protein complexes, regulates blood-testis barrier dynamics.
|
Int J Biochem Cell Biol
|
2010
|
1.37
|
|
23
|
An intracellular trafficking pathway in the seminiferous epithelium regulating spermatogenesis: a biochemical and molecular perspective.
|
Crit Rev Biochem Mol Biol
|
2009
|
1.33
|
|
24
|
Drug transporter, P-glycoprotein (MDR1), is an integrated component of the mammalian blood-testis barrier.
|
Int J Biochem Cell Biol
|
2009
|
1.29
|
|
25
|
An occludin-focal adhesion kinase protein complex at the blood-testis barrier: a study using the cadmium model.
|
Endocrinology
|
2009
|
1.28
|
|
26
|
Focal adhesion kinase is a blood-testis barrier regulator.
|
Proc Natl Acad Sci U S A
|
2009
|
1.26
|
|
27
|
Focal adhesion kinase-Tyr407 and -Tyr397 exhibit antagonistic effects on blood-testis barrier dynamics in the rat.
|
Proc Natl Acad Sci U S A
|
2012
|
1.22
|
|
28
|
Cytokines and junction restructuring during spermatogenesis--a lesson to learn from the testis.
|
Cytokine Growth Factor Rev
|
2005
|
1.21
|
|
29
|
Dynamin II interacts with the cadherin- and occludin-based protein complexes at the blood-testis barrier in adult rat testes.
|
J Endocrinol
|
2006
|
1.21
|
|
30
|
Regulation of ectoplasmic specialization dynamics in the seminiferous epithelium by focal adhesion-associated proteins in testosterone-suppressed rat testes.
|
Endocrinology
|
2004
|
1.20
|
|
31
|
Fer kinase/FerT and adherens junction dynamics in the testis: an in vitro and in vivo study.
|
Biol Reprod
|
2003
|
1.20
|
|
32
|
Cytoskeletal dynamics and spermatogenesis.
|
Philos Trans R Soc Lond B Biol Sci
|
2010
|
1.19
|
|
33
|
Regulation of spermiogenesis, spermiation and blood-testis barrier dynamics: novel insights from studies on Eps8 and Arp3.
|
Biochem J
|
2011
|
1.15
|
|
34
|
Regulation of blood-testis barrier dynamics by TGF-beta3 is a Cdc42-dependent protein trafficking event.
|
Proc Natl Acad Sci U S A
|
2010
|
1.15
|
|
35
|
Junction restructuring and spermatogenesis: the biology, regulation, and implication in male contraceptive development.
|
Curr Top Dev Biol
|
2008
|
1.14
|
|
36
|
The biology of the desmosome-like junction a versatile anchoring junction and signal transducer in the seminiferous epithelium.
|
Int Rev Cell Mol Biol
|
2011
|
1.12
|
|
37
|
Sertoli-germ cell junctions in the testis: a review of recent data.
|
Philos Trans R Soc Lond B Biol Sci
|
2010
|
1.12
|
|
38
|
Regulation of spermatogenesis in the microenvironment of the seminiferous epithelium: new insights and advances.
|
Mol Cell Endocrinol
|
2009
|
1.11
|
|
39
|
Adjudin, a potential male contraceptive, exerts its effects locally in the seminiferous epithelium of mammalian testes.
|
Reproduction
|
2011
|
1.11
|
|
40
|
Cytokines and junction restructuring events during spermatogenesis in the testis: an emerging concept of regulation.
|
Cytokine Growth Factor Rev
|
2009
|
1.11
|
|
41
|
Mitogen-activated protein kinases in male reproductive function.
|
Trends Mol Med
|
2009
|
1.10
|
|
42
|
Regulation of Sertoli-germ cell adherens junction dynamics via changes in protein-protein interactions of the N-cadherin-beta-catenin protein complex which are possibly mediated by c-Src and myotubularin-related protein 2: an in vivo study using an androgen suppression model.
|
Endocrinology
|
2004
|
1.10
|
|
43
|
A peptide derived from laminin-γ3 reversibly impairs spermatogenesis in rats.
|
Nat Commun
|
2012
|
1.09
|
|
44
|
Palladin is a regulator of actin filament bundles at the ectoplasmic specialization in adult rat testes.
|
Endocrinology
|
2013
|
1.08
|
|
45
|
Differential effects of testosterone and TGF-β3 on endocytic vesicle-mediated protein trafficking events at the blood-testis barrier.
|
Exp Cell Res
|
2010
|
1.08
|
|
46
|
Blood-testis barrier dynamics are regulated by {alpha}2-macroglobulin via the c-Jun N-terminal protein kinase pathway.
|
Endocrinology
|
2004
|
1.07
|
|
47
|
Coxsackie and adenovirus receptor (CAR) is a product of Sertoli and germ cells in rat testes which is localized at the Sertoli-Sertoli and Sertoli-germ cell interface.
|
Exp Cell Res
|
2007
|
1.07
|
|
48
|
Connexin 43 is critical to maintain the homeostasis of the blood-testis barrier via its effects on tight junction reassembly.
|
Proc Natl Acad Sci U S A
|
2010
|
1.07
|
|
49
|
c-Yes regulates cell adhesion at the blood-testis barrier and the apical ectoplasmic specialization in the seminiferous epithelium of rat testes.
|
Int J Biochem Cell Biol
|
2011
|
1.06
|
|
50
|
P-glycoprotein regulates blood-testis barrier dynamics via its effects on the occludin/zonula occludens 1 (ZO-1) protein complex mediated by focal adhesion kinase (FAK).
|
Proc Natl Acad Sci U S A
|
2011
|
1.05
|
|
51
|
Drug transporters, the blood-testis barrier, and spermatogenesis.
|
J Endocrinol
|
2010
|
1.05
|
|
52
|
Actin-binding protein drebrin E is involved in junction dynamics during spermatogenesis.
|
Spermatogenesis
|
2011
|
1.03
|
|
53
|
Interleukin 1 alpha (IL1A) is a novel regulator of the blood-testis barrier in the rat.
|
Biol Reprod
|
2007
|
1.02
|
|
54
|
Adjudin attenuates lipopolysaccharide (LPS)- and ischemia-induced microglial activation.
|
J Neuroimmunol
|
2012
|
1.01
|
|
55
|
Interleukin-1alpha is a regulator of the blood-testis barrier.
|
FASEB J
|
2010
|
1.01
|
|
56
|
Drug transporters and blood--testis barrier function.
|
J Endocrinol
|
2011
|
1.01
|
|
57
|
C-type natriuretic peptide regulates blood-testis barrier dynamics in adult rat testes.
|
Proc Natl Acad Sci U S A
|
2007
|
1.00
|
|
58
|
Rab8B GTPase and junction dynamics in the testis.
|
Endocrinology
|
2003
|
1.00
|
|
59
|
New frontiers in nonhormonal male contraception.
|
Contraception
|
2010
|
1.00
|
|
60
|
Adjudin-mediated Sertoli-germ cell junction disassembly affects Sertoli cell barrier function in vitro and in vivo.
|
Int J Biochem Cell Biol
|
2010
|
0.99
|
|
61
|
Regulation of Sertoli-germ cell adherens junction dynamics in the testis via the nitric oxide synthase (NOS)/cGMP/protein kinase G (PRKG)/beta-catenin (CATNB) signaling pathway: an in vitro and in vivo study.
|
Biol Reprod
|
2005
|
0.99
|
|
62
|
rpS6 Regulates blood-testis barrier dynamics by affecting F-actin organization and protein recruitment.
|
Endocrinology
|
2012
|
0.99
|
|
63
|
Adjudin disrupts spermatogenesis via the action of some unlikely partners: Eps8, Arp2/3 complex, drebrin E, PAR6 and 14-3-3.
|
Spermatogenesis
|
2011
|
0.98
|
|
64
|
Regulation of blood-testis barrier dynamics by desmosome, gap junction, hemidesmosome and polarity proteins: An unexpected turn of events.
|
Spermatogenesis
|
2011
|
0.96
|
|
65
|
c-Yes regulates cell adhesion at the apical ectoplasmic specialization-blood-testis barrier axis via its effects on protein recruitment and distribution.
|
Am J Physiol Endocrinol Metab
|
2012
|
0.96
|
|
66
|
Rictor/mTORC2 regulates blood-testis barrier dynamics via its effects on gap junction communications and actin filament network.
|
FASEB J
|
2013
|
0.95
|
|
67
|
Environmental toxicants and male reproductive function.
|
Spermatogenesis
|
2011
|
0.94
|
|
68
|
Targeted and reversible disruption of the blood-testis barrier by an FSH mutant-occludin peptide conjugate.
|
FASEB J
|
2006
|
0.94
|
|
69
|
Perfluorooctanesulfonate (PFOS) perturbs male rat Sertoli cell blood-testis barrier function by affecting F-actin organization via p-FAK-Tyr(407): an in vitro study.
|
Endocrinology
|
2013
|
0.94
|
|
70
|
MAP/microtubule affinity-regulating kinases, microtubule dynamics, and spermatogenesis.
|
J Endocrinol
|
2013
|
0.93
|
|
71
|
Unraveling the molecular targets pertinent to junction restructuring events during spermatogenesis using the Adjudin-induced germ cell depletion model.
|
J Endocrinol
|
2007
|
0.93
|
|
72
|
p-FAK-Tyr(397) regulates spermatid adhesion in the rat testis via its effects on F-actin organization at the ectoplasmic specialization.
|
Am J Physiol Endocrinol Metab
|
2013
|
0.93
|
|
73
|
The biology of spermatogenesis: the past, present and future.
|
Philos Trans R Soc Lond B Biol Sci
|
2010
|
0.93
|
|
74
|
The Scribble/Lgl/Dlg polarity protein complex is a regulator of blood-testis barrier dynamics and spermatid polarity during spermatogenesis.
|
Endocrinology
|
2012
|
0.93
|
|
75
|
Gap junctions and blood-tissue barriers.
|
Adv Exp Med Biol
|
2012
|
0.92
|
|
76
|
Actin binding proteins and spermiogenesis: Some unexpected findings.
|
Spermatogenesis
|
2011
|
0.91
|
|
77
|
The Sertoli-spermatid junctional complex adhesion strength is affected in vitro by adjudin.
|
J Androl
|
2006
|
0.91
|
|
78
|
Intercellular adhesion molecules (ICAMs) and spermatogenesis.
|
Hum Reprod Update
|
2013
|
0.90
|
|
79
|
Regulation of blood-testis barrier dynamics by focal adhesion kinase (FAK): an unexpected turn of events.
|
Cell Cycle
|
2009
|
0.89
|
|
80
|
Myotubularin phosphoinositide phosphatases, protein phosphatases, and kinases: their roles in junction dynamics and spermatogenesis.
|
J Cell Physiol
|
2005
|
0.88
|
|
81
|
A study to assess the assembly of a functional blood-testis barrier in developing rat testes.
|
Spermatogenesis
|
2011
|
0.88
|
|
82
|
The β1-integrin-p-FAK-p130Cas-DOCK180-RhoA-vinculin is a novel regulatory protein complex at the apical ectoplasmic specialization in adult rat testes.
|
Spermatogenesis
|
2011
|
0.88
|
|
83
|
C-Src and c-Yes are two unlikely partners of spermatogenesis and their roles in blood-testis barrier dynamics.
|
Adv Exp Med Biol
|
2012
|
0.88
|
|
84
|
Filamin A is a regulator of blood-testis barrier assembly during postnatal development in the rat testis.
|
Endocrinology
|
2012
|
0.87
|
|
85
|
Targeting testis-specific proteins to inhibit spermatogenesis: lesson from endocrine disrupting chemicals.
|
Expert Opin Ther Targets
|
2013
|
0.87
|
|
86
|
Regulation of blood-testis barrier (BTB) dynamics during spermatogenesis via the "Yin" and "Yang" effects of mammalian target of rapamycin complex 1 (mTORC1) and mTORC2.
|
Int Rev Cell Mol Biol
|
2013
|
0.86
|
|
87
|
Environmental toxicants perturb human Sertoli cell adhesive function via changes in F-actin organization mediated by actin regulatory proteins.
|
Hum Reprod
|
2014
|
0.86
|
|
88
|
Intercellular adhesion molecule-1 is a regulator of blood-testis barrier function.
|
J Cell Sci
|
2012
|
0.86
|
|
89
|
Male contraceptive Adjudin is a potential anti-cancer drug.
|
Biochem Pharmacol
|
2012
|
0.86
|
|
90
|
Regulation of actin dynamics and protein trafficking during spermatogenesis--insights into a complex process.
|
Crit Rev Biochem Mol Biol
|
2013
|
0.86
|
|
91
|
Coordinating cellular events during spermatogenesis: a biochemical model.
|
Trends Biochem Sci
|
2009
|
0.86
|
|
92
|
Tumor necrosis factor α-mediated restructuring of the Sertoli cell barrier in vitro involves matrix metalloprotease 9 (MMP9), membrane-bound intercellular adhesion molecule-1 (ICAM-1) and the actin cytoskeleton.
|
Spermatogenesis
|
2012
|
0.85
|
|
93
|
Signalling pathways regulating the blood-testis barrier.
|
Int J Biochem Cell Biol
|
2012
|
0.85
|
|
94
|
An in vivo study on adjudin and blood-testis barrier dynamics.
|
Endocrinology
|
2009
|
0.85
|
|
95
|
Interactions among IQGAP1, Cdc42, and the cadherin/catenin protein complex regulate Sertoli-germ cell adherens junction dynamics in the testis.
|
J Cell Physiol
|
2005
|
0.84
|
|
96
|
Regulation of the blood-testis barrier by coxsackievirus and adenovirus receptor.
|
Am J Physiol Cell Physiol
|
2012
|
0.84
|
|
97
|
Adjudin-mediated junction restructuring in the seminiferous epithelium leads to displacement of soluble guanylate cyclase from adherens junctions.
|
J Cell Physiol
|
2006
|
0.83
|
|
98
|
Interactions of laminin β3 fragment with β1-integrin receptor: A revisit of the apical ectoplasmic specialization-blood-testis-barrier-hemidesmosome functional axis in the testis.
|
Spermatogenesis
|
2011
|
0.83
|
|
99
|
Breast cancer resistance protein regulates apical ectoplasmic specialization dynamics stage specifically in the rat testis.
|
Am J Physiol Endocrinol Metab
|
2013
|
0.83
|
|
100
|
Cross-talk between tight and anchoring junctions-lesson from the testis.
|
Adv Exp Med Biol
|
2008
|
0.83
|
|
101
|
Microtubule affinity-regulating kinase 4 (MARK4) is a component of the ectoplasmic specialization in the rat testis.
|
Spermatogenesis
|
2012
|
0.82
|
|
102
|
Actin cross-linking protein palladin and spermatogenesis.
|
Spermatogenesis
|
2013
|
0.82
|
|
103
|
Filamin A: A regulator of blood-testis barrier assembly during post-natal development.
|
Spermatogenesis
|
2012
|
0.82
|
|
104
|
Adjudin targeting rabbit germ cell adhesion as a male contraceptive: a pharmacokinetics study.
|
J Androl
|
2008
|
0.82
|
|
105
|
Cellular localization of sphingomyelin synthase 2 in the seminiferous epithelium of adult rat testes.
|
J Endocrinol
|
2007
|
0.82
|
|
106
|
Role of P-glycoprotein at the blood-testis barrier on adjudin distribution in the testis: a revisit of recent data.
|
Adv Exp Med Biol
|
2012
|
0.81
|
|
107
|
Adherens junction dynamics in the testis and spermatogenesis.
|
J Androl
|
2003
|
0.80
|
|
108
|
Intercellular adhesion molecule-2 is involved in apical ectoplasmic specialization dynamics during spermatogenesis in the rat.
|
J Endocrinol
|
2013
|
0.80
|
|
109
|
The biology of interleukin-1: emerging concepts in the regulation of the actin cytoskeleton and cell junction dynamics.
|
Cell Mol Life Sci
|
2011
|
0.80
|
|
110
|
Polarity protein complex Scribble/Lgl/Dlg and epithelial cell barriers.
|
Adv Exp Med Biol
|
2012
|
0.79
|
|
111
|
Rai14 (retinoic acid induced protein 14) is involved in regulating f-actin dynamics at the ectoplasmic specialization in the rat testis*.
|
PLoS One
|
2013
|
0.79
|
|
112
|
Breast cancer resistance protein (Bcrp) and the testis--an unexpected turn of events.
|
Asian J Androl
|
2013
|
0.79
|
|
113
|
Testicular cell junction: a novel target for male contraception.
|
Curr Med Chem
|
2009
|
0.78
|
|
114
|
The apical ES-BTB-BM functional axis is an emerging target for toxicant-induced infertility.
|
Trends Mol Med
|
2013
|
0.78
|
|
115
|
Sertoli cells are the target of environmental toxicants in the testis - a mechanistic and therapeutic insight.
|
Expert Opin Ther Targets
|
2015
|
0.77
|
|
116
|
Regulation of drug transporters in the testis by environmental toxicant cadmium, steroids and cytokines.
|
Spermatogenesis
|
2012
|
0.77
|
|
117
|
Adjudin disrupts spermatogenesis by targeting drug transporters: Lesson from the breast cancer resistance protein (BCRP).
|
Spermatogenesis
|
2013
|
0.76
|
|
118
|
RAI14 (retinoic acid induced protein 14) is an F-actin regulator: Lesson from the testis.
|
Spermatogenesis
|
2013
|
0.75
|
|
119
|
Actin binding proteins in blood-testis barrier function.
|
Curr Opin Endocrinol Diabetes Obes
|
2015
|
0.75
|
|
120
|
Male contraception: Where do we go from here?
|
Spermatogenesis
|
2011
|
0.75
|
|
121
|
Effective Delivery of Male Contraceptives Behind the Blood-Testis Barrier (BTB) - Lesson from Adjudin.
|
Curr Med Chem
|
2016
|
0.75
|
|
122
|
Sertolin mediates blood-testis barrier restructuring.
|
Endocrinology
|
2014
|
0.75
|
|
123
|
Alpha2-macroglobulin expression in the liver in response to inflammation is mediated by the testis.
|
J Endocrinol
|
2005
|
0.75
|