Multivariate analysis of male reproductive function in Inpp5b-/- mice reveals heterogeneity in defects in fertility, sperm-egg membrane interaction and proteolytic cleavage of sperm ADAMs.

PubWeight™: 0.80‹?›

🔗 View Article (PMC 2882869)

Published in Mol Hum Reprod on April 19, 2010

Authors

Matthew R Marcello1, Janice P Evans

Author Affiliations

1: Division of Reproductive Biology, Department of Biochemistry and Molecular Biology, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, 615 N. Wolfe St., Baltimore, MD 21205, USA.

Articles cited by this

The immunoglobulin superfamily protein Izumo is required for sperm to fuse with eggs. Nature (2005) 4.07

Genetic dissection of mammalian fertility pathways. Nat Cell Biol (2002) 3.99

The Lowe's oculocerebrorenal syndrome gene encodes a protein highly homologous to inositol polyphosphate-5-phosphatase. Nature (1992) 2.64

The role of the inositol polyphosphate 5-phosphatases in cellular function and human disease. Biochem J (2009) 1.97

Functional overlap between murine Inpp5b and Ocrl1 may explain why deficiency of the murine ortholog for OCRL1 does not cause Lowe syndrome in mice. J Clin Invest (1998) 1.59

Performance of ten inbred mouse strains following assisted reproductive technologies (ARTs). Theriogenology (2005) 1.50

Properties of type II inositol polyphosphate 5-phosphatase. J Biol Chem (1995) 1.38

A role for the disintegrin domain of cyritestin, a sperm surface protein belonging to the ADAM family, in mouse sperm-egg plasma membrane adhesion and fusion. J Cell Biol (1997) 1.33

Izumo is part of a multiprotein family whose members form large complexes on mammalian sperm. Mol Reprod Dev (2009) 1.33

Analysis of loss of adhesive function in sperm lacking cyritestin or fertilin beta. Dev Biol (2001) 1.32

Mouse sperm-egg plasma membrane interactions: analysis of roles of egg integrins and the mouse sperm homologue of PH-30 (fertilin) beta. J Cell Sci (1995) 1.21

The power of mouse genetics to study spermatogenesis. J Androl (2009) 1.08

New insights into the molecular basis of mammalian sperm-egg membrane interactions. Front Biosci (2008) 1.05

Localization of low-density detergent-resistant membrane proteins in intact and acrosome-reacted mouse sperm. Biol Reprod (2009) 1.03

Tssk6 is required for Izumo relocalization and gamete fusion in the mouse. J Cell Sci (2009) 1.01

Analysis of mouse fertilin in wild-type and fertilin beta(-/-) sperm: evidence for C-terminal modification, alpha/beta dimerization, and lack of essential role of fertilin alpha in sperm-egg fusion. Dev Biol (2000) 1.00

Disrupted sperm function and fertilin beta processing in mice deficient in the inositol polyphosphate 5-phosphatase Inpp5b. Dev Biol (2001) 0.99

Evidence for distinct serine protease activities with a potential role in processing the sperm protein fertilin. Dev Biol (1997) 0.98

Detection of differences in fertility. J Androl (2002) 0.97

Comprehensive analysis of reproductive ADAMs: relationship of ADAM4 and ADAM6 with an ADAM complex required for fertilization in mice. Biol Reprod (2009) 0.96

Capacitation-related changes in antigen distribution on mouse sperm heads and its relation to fertilization rate in vitro. J Reprod Immunol (1987) 0.95

The relationship between sperm concentration and fertilization in vitro of mouse eggs. Biol Reprod (1975) 0.94

Sertoli cell vacuolization and abnormal germ cell adhesion in mice deficient in an inositol polyphosphate 5-phosphatase. Biol Reprod (2002) 0.94

In vitro elucidation of substrate specificity and bioassay of proprotein convertase 4 using intramolecularly quenched fluorogenic peptides. Biochem J (2004) 0.92

Fertility comparison between wild type and transgenic mice by in vitro fertilization. Transgenic Res (2009) 0.92

Sperm defects in mice lacking a functional Niemann-Pick C1 protein. Mol Reprod Dev (2006) 0.88

Reduction of mouse egg surface integrin alpha9 subunit (ITGA9) reduces the egg's ability to support sperm-egg binding and fusion. Biol Reprod (2009) 0.88

Immunoglobulin superfamily member IgSF8 (EWI-2) and CD9 in fertilisation: evidence of distinct functions for CD9 and a CD9-associated protein in mammalian sperm-egg interaction. Reprod Fertil Dev (2009) 0.87

Strain differences in the in vitro fertilizing capacity of mouse spermatozoa as tested in various media. Biol Reprod (1976) 0.85

Analysis of Mammalian sperm-egg membrane interactions during in vitro fertilization. Methods Mol Biol (2006) 0.83

Pre-loading of mouse oocytes with DNA-specific fluorochrome (Hoechst 33342) permits rapid detection of sperm-oocyte fusion. J Reprod Fertil (1988) 0.82

PCSK4-null sperm display enhanced protein tyrosine phosphorylation and ADAM2 proteolytic processing during in vitro capacitation. Fertil Steril (2009) 0.82

Mouse sperm genotype and the rate of egg penetration in vitro. J Exp Zool (1976) 0.81

Articles by these authors

BRCA2 deficiency in mice leads to meiotic impairment and infertility. Development (2003) 1.55

Mammalian membrane block to polyspermy: new insights into how mammalian eggs prevent fertilisation by multiple sperm. Reprod Fertil Dev (2006) 1.26

Targeted disruption of tyrosylprotein sulfotransferase-2, an enzyme that catalyzes post-translational protein tyrosine O-sulfation, causes male infertility. J Biol Chem (2006) 1.15

Cortical mechanics and meiosis II completion in mammalian oocytes are mediated by myosin-II and Ezrin-Radixin-Moesin (ERM) proteins. Mol Biol Cell (2010) 1.13

New insights into the molecular basis of mammalian sperm-egg membrane interactions. Front Biosci (2008) 1.05

Involvement of calcium signaling and the actin cytoskeleton in the membrane block to polyspermy in mouse eggs. Biol Reprod (2002) 0.99

Calcium and sperm components in the establishment of the membrane block to polyspermy: studies of ICSI and activation with sperm factor. Mol Hum Reprod (2007) 0.98

Establishment of the mammalian membrane block to polyspermy: evidence for calcium-dependent and -independent regulation. Reproduction (2007) 0.97

Lack of tyrosylprotein sulfotransferase-2 activity results in altered sperm-egg interactions and loss of ADAM3 and ADAM6 in epididymal sperm. J Biol Chem (2011) 0.91

Analysis of the roles of RGD-binding integrins, alpha(4)/alpha(9) integrins, alpha(6) integrins, and CD9 in the interaction of the fertilin beta (ADAM2) disintegrin domain with the mouse egg membrane. Biol Reprod (2002) 0.91

Reduction of mouse egg surface integrin alpha9 subunit (ITGA9) reduces the egg's ability to support sperm-egg binding and fusion. Biol Reprod (2009) 0.88

Membrane fusions during mammalian fertilization. Adv Exp Med Biol (2011) 0.87

Immunoglobulin superfamily member IgSF8 (EWI-2) and CD9 in fertilisation: evidence of distinct functions for CD9 and a CD9-associated protein in mammalian sperm-egg interaction. Reprod Fertil Dev (2009) 0.87

Analysis of Mammalian sperm-egg membrane interactions during in vitro fertilization. Methods Mol Biol (2006) 0.83

Membrane and cortical abnormalities in post-ovulatory aged eggs: analysis of fertilizability and establishment of the membrane block to polyspermy. Mol Hum Reprod (2004) 0.82

CaMKII can participate in but is not sufficient for the establishment of the membrane block to polyspermy in mouse eggs. J Cell Physiol (2007) 0.82

ADAM2 interactions with mouse eggs and cell lines expressing α4/α9 (ITGA4/ITGA9) integrins: implications for integrin-based adhesion and fertilization. PLoS One (2010) 0.80

Prophase I mouse oocytes are deficient in the ability to respond to fertilization by decreasing membrane receptivity to sperm and establishing a membrane block to polyspermy. Biol Reprod (2013) 0.78

Ultrastructural analysis of egg membrane abnormalities in post-ovulatory aged eggs. Int J Dev Biol (2008) 0.77

Setting up asymmetric cell division in the mouse egg. Mol Reprod Dev (2011) 0.75

Synopsis: 2005 annual meeting of the American Society of Andrology. J Androl (2005) 0.75