Published in Fertil Steril on April 01, 2009
Protein-tyrosine kinase signaling in the biological functions associated with sperm. J Signal Transduct (2012) 0.82
Phospholipase B is activated in response to sterol removal and stimulates acrosome exocytosis in murine sperm. J Biol Chem (2013) 0.81
Multivariate analysis of male reproductive function in Inpp5b-/- mice reveals heterogeneity in defects in fertility, sperm-egg membrane interaction and proteolytic cleavage of sperm ADAMs. Mol Hum Reprod (2010) 0.80
Alteration in the processing of the ACRBP/sp32 protein and sperm head/acrosome malformations in proprotein convertase 4 (PCSK4) null mice. Mol Hum Reprod (2012) 0.78
Characterization of Mammalian ADAM2 and Its Absence from Human Sperm. PLoS One (2016) 0.75
Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature (2002) 37.66
Large-scale mapping of human protein-protein interactions by mass spectrometry. Mol Syst Biol (2007) 8.16
Human Proteinpedia enables sharing of human protein data. Nat Biotechnol (2008) 4.21
PCSK9: a key modulator of cardiovascular health. Circ Res (2014) 1.71
The tale of two domains: proteomics and genomics analysis of SMYD2, a new histone methyltransferase. Mol Cell Proteomics (2007) 1.70
Plasma PCSK9 levels are significantly modified by statins and fibrates in humans. Lipids Health Dis (2008) 1.56
HysTag--a novel proteomic quantification tool applied to differential display analysis of membrane proteins from distinct areas of mouse brain. Mol Cell Proteomics (2003) 1.52
The proteomic reactor: a microfluidic device for processing minute amounts of protein prior to mass spectrometry analysis. J Proteome Res (2006) 1.51
Glycoproteomic reactor for human plasma. J Proteome Res (2009) 1.49
Proteomic analyses of the SMYD family interactomes identify HSP90 as a novel target for SMYD2. J Mol Cell Biol (2011) 1.48
Tryptic digestion of ubiquitin standards reveals an improved strategy for identifying ubiquitinated proteins by mass spectrometry. Proteomics (2007) 1.43
A novel proteomics approach for the discovery of chromatin-associated protein networks. Mol Cell Proteomics (2008) 1.42
Death-associated protein 4 binds MST1 and augments MST1-induced apoptosis. J Biol Chem (2002) 1.41
Functional dissection of the NuA4 histone acetyltransferase reveals its role as a genetic hub and that Eaf1 is essential for complex integrity. Mol Cell Biol (2008) 1.38
Proteomic analysis of ubiquitinated proteins from human MCF-7 breast cancer cells by immunoaffinity purification and mass spectrometry. J Proteome Res (2005) 1.34
The cysteine-rich domain of the secreted proprotein convertases PC5A and PACE4 functions as a cell surface anchor and interacts with tissue inhibitors of metalloproteinases. Mol Biol Cell (2005) 1.30
Plasma PCSK9 levels correlate with cholesterol in men but not in women. Biochem Biophys Res Commun (2007) 1.27
The multifaceted proprotein convertases: their unique, redundant, complementary, and opposite functions. J Biol Chem (2013) 1.27
Two-color cell array screen reveals interdependent roles for histone chaperones and a chromatin boundary regulator in histone gene repression. Mol Cell (2009) 1.24
Deletion of the gene encoding proprotein convertase 5/6 causes early embryonic lethality in the mouse. Mol Cell Biol (2006) 1.23
Activation of the Cdc42p GTPase by cyclin-dependent protein kinases in budding yeast. EMBO J (2007) 1.20
Lipidomics era: accomplishments and challenges. Mass Spectrom Rev (2010) 1.20
Defining the budding yeast chromatin-associated interactome. Mol Syst Biol (2010) 1.19
Involvement of matrix metalloproteinases in the adipose conversion of 3T3-L1 preadipocytes. Biochem J (2002) 1.18
Functional analysis of the missense APOC3 mutation Ala23Thr associated with human hypotriglyceridemia. J Lipid Res (2010) 1.15
Novel loss-of-function PCSK9 variant is associated with low plasma LDL cholesterol in a French-Canadian family and with impaired processing and secretion in cell culture. Clin Chem (2011) 1.14
The functional diversity of protein lysine methylation. Mol Syst Biol (2014) 1.11
Altered processing of the neurotensin/neuromedin N precursor in PC2 knock down mice: a biochemical and immunohistochemical study. J Neurochem (2002) 1.08
15-Deoxy-delta 12,14-prostaglandins D2 and J2 are potent activators of human eosinophils. J Immunol (2002) 1.08
Nonsynonymous mutations within APOB in human familial hypobetalipoproteinemia: evidence for feedback inhibition of lipogenesis and postendoplasmic reticulum degradation of apolipoprotein B. J Biol Chem (2009) 1.07
Exploring the yeast acetylome using functional genomics. Cell (2012) 1.05
Mapping protein-protein interactions by mass spectrometry. Curr Opin Biotechnol (2006) 1.02
Biomarker assay translation from discovery to clinical studies in cancer drug development: quantification of emerging protein biomarkers. Adv Cancer Res (2007) 1.00
Proteomics in 2005/2006: developments, applications and challenges. Anal Chem (2007) 0.99
Role of pro-IGF-II processing by proprotein convertase 4 in human placental development. Proc Natl Acad Sci U S A (2005) 0.99
Proteomics: from gel based to gel free. Anal Chem (2005) 0.99
PCSK9 is phosphorylated by a Golgi casein kinase-like kinase ex vivo and circulates as a phosphoprotein in humans. FEBS J (2008) 0.99
Rare cell proteomic reactor applied to stable isotope labeling by amino acids in cell culture (SILAC)-based quantitative proteomics study of human embryonic stem cell differentiation. Mol Cell Proteomics (2010) 0.98
Amyloid-beta42 signals tau hyperphosphorylation and compromises neuronal viability by disrupting alkylacylglycerophosphocholine metabolism. Proc Natl Acad Sci U S A (2009) 0.96
A Regulatory Network Involving β-Catenin, e-Cadherin, PI3k/Akt, and Slug Balances Self-Renewal and Differentiation of Human Pluripotent Stem Cells In Response to Wnt Signaling. Stem Cells (2015) 0.94
Analytical aspects of proteomics: 2009-2010. Anal Chem (2011) 0.93
From cells to peptides: "one-stop" integrated proteomic processing using amphipols. J Proteome Res (2013) 0.93
Advancements in top-down proteomics. Anal Chem (2011) 0.92
In vitro elucidation of substrate specificity and bioassay of proprotein convertase 4 using intramolecularly quenched fluorogenic peptides. Biochem J (2004) 0.92
Differential regulation of wild-type and mutant alpha-synuclein binding to synaptic membranes by cytosolic factors. BMC Neurosci (2008) 0.91
Recent developments in mass spectrometry-based quantitative phosphoproteomics. Biochem Cell Biol (2008) 0.91
The proteomic reactor facilitates the analysis of affinity-purified proteins by mass spectrometry: application for identifying ubiquitinated proteins in human cells. J Proteome Res (2007) 0.91
Lipin - The bridge between hepatic glycerolipid biosynthesis and lipoprotein metabolism. Biochim Biophys Acta (2010) 0.90
Regulation of septin dynamics by the Saccharomyces cerevisiae lysine acetyltransferase NuA4. PLoS One (2011) 0.90
Recombinant proprotein convertase 4 (PC4) from Leishmania tarentolae expression system: purification, biochemical study and inhibitor design. Protein Expr Purif (2008) 0.89
The liver connexin32 interactome is a novel plasma membrane-mitochondrial signaling nexus. J Proteome Res (2013) 0.88
A novel whole-cell lysate kinase assay identifies substrates of the p38 MAPK in differentiating myoblasts. Skelet Muscle (2012) 0.88
Proprotein convertases as therapeutic targets. Expert Opin Ther Targets (2008) 0.88
Using neurolipidomics to identify phospholipid mediators of synaptic (dys)function in Alzheimer's Disease. Front Physiol (2013) 0.88
Proprotein convertase subtilisin/kexin type 4 in mammalian fertility: a review. Hum Reprod Update (2008) 0.88
Proprotein convertases are important mediators of the adipocyte differentiation of mouse 3T3-L1 cells. J Cell Sci (2002) 0.88
Definition and characterization of a "trypsinosome" from specific peptide characteristics by nano-HPLC-MS/MS and in silico analysis of complex protein mixtures. J Proteome Res (2004) 0.88
Improved recovery and identification of membrane proteins from rat hepatic cells using a centrifugal proteomic reactor. Mol Cell Proteomics (2011) 0.87
Differential effects of PCSK9 loss of function variants on serum lipid and PCSK9 levels in Caucasian and African Canadian populations. Lipids Health Dis (2013) 0.87
Microsome-associated lumenal lipid droplets in the regulation of lipoprotein secretion. Curr Opin Lipidol (2013) 0.86
Lyso-form fragment ions facilitate the determination of stereospecificity of diacyl glycerophospholipids. Rapid Commun Mass Spectrom (2011) 0.86
Improvement of the quantification accuracy and throughput for phosphoproteome analysis by a pseudo triplex stable isotope dimethyl labeling approach. Anal Chem (2011) 0.86
A differential phosphoproteomic analysis of retinoic acid-treated P19 cells. J Proteome Res (2007) 0.85
Proteomic reactors and their applications in biology. FEBS J (2011) 0.85
Allelic clustering and ancestry-dependent frequencies of rs6232, rs6234, and rs6235 PCSK1 SNPs in a Northern Ontario population sample. J Community Genet (2012) 0.85
Sperm from mice genetically deficient for the PCSK4 proteinase exhibit accelerated capacitation, precocious acrosome reaction, reduced binding to egg zona pellucida, and impaired fertilizing ability. Biol Reprod (2005) 0.85
Visualization and Phospholipid Identification (VaLID): online integrated search engine capable of identifying and visualizing glycerophospholipids with given mass. Bioinformatics (2012) 0.85
Differences of pancreatic expression of 7B2 between C57BL/6J and C3H/HeJ mice and genetic polymorphisms at its locus (Sgne1). Diabetes (2006) 0.85
Restriction of histone gene transcription to S phase by phosphorylation of a chromatin boundary protein. Genes Dev (2011) 0.85
Skeletal myosin light chain kinase regulates skeletal myogenesis by phosphorylation of MEF2C. EMBO J (2011) 0.84
Uncovering the proteome response of the master circadian clock to light using an AutoProteome system. Mol Cell Proteomics (2011) 0.84
Proteomics: from technology developments to biological applications. Anal Chem (2009) 0.83
Targeted lipidomics - advances in profiling lysophosphocholine and platelet-activating factor second messengers. FEBS J (2013) 0.83
Gelsolin regulates cisplatin sensitivity in human head-and-neck cancer. Int J Cancer (2014) 0.83
Of proteins and DNA--proteomic role in the field of chromatin research. Mol Biosyst (2009) 0.82
Srf1 is a novel regulator of phospholipase D activity and is essential to buffer the toxic effects of C16:0 platelet activating factor. PLoS Genet (2011) 0.82
Myosin phosphatase modulates the cardiac cell fate by regulating the subcellular localization of Nkx2.5 in a Wnt/Rho-associated protein kinase-dependent pathway. Circ Res (2012) 0.82
Fine tuning of proteomic technologies to improve biological findings: advancements in 2011-2013. Anal Chem (2013) 0.82
Increased stress-induced analgesia in mice lacking the proneuropeptide convertase PC2. Neurosci Lett (2006) 0.82
Expression of PCSK1 (PC1/3), PCSK2 (PC2) and PCSK3 (furin) in mouse small intestine. Regul Pept (2008) 0.81
Analysis of the subcellular phosphoproteome using a novel phosphoproteomic reactor. J Proteome Res (2010) 0.81
Quantitative proteomic analysis of PCSK9 gain of function in human hepatic HuH7 cells. J Proteome Res (2011) 0.81
Proteomics technology in systems biology. Mol Biosyst (2006) 0.81
Multiplexed proteomic reactor for the processing of proteomic samples. Anal Chem (2007) 0.81
PCSK2-null mice exhibit delayed intestinal motility, reduced refeeding response and altered plasma levels of several regulatory peptides. Life Sci (2010) 0.80
New ammunition for the proteomic reactor: strong anion exchange beads and multiple enzymes enhance protein identification and sequence coverage. Anal Bioanal Chem (2010) 0.80
Phospholipase C activity affinity purifies with the Torpedo nicotinic acetylcholine receptor. J Biol Chem (2010) 0.80
Systematic determination of ion score cutoffs based on calculated false positive rates: application for identifying ubiquitinated proteins by tandem mass spectrometry. J Mass Spectrom (2008) 0.80
Analysis of protein interaction networks using mass spectrometry compatible techniques. Anal Chim Acta (2006) 0.80
Identification of protein-protein interactions by mass spectrometry coupled techniques. Adv Biochem Eng Biotechnol (2008) 0.79
On-line strong cation exchange micro-HPLC-ESI-MS/MS for protein identification and process optimization. J Am Soc Mass Spectrom (2003) 0.79
Identification of lysophosphatidylcholine (LPC) and platelet activating factor (PAF) from PC12 cells and mouse cortex using liquid chromatography/multi-stage mass spectrometry (LC/MS3). Rapid Commun Mass Spectrom (2008) 0.79