Published in J Immunol on April 19, 2010
Biology and pathogenesis of chikungunya virus. Nat Rev Microbiol (2010) 3.53
Persistent arthralgia induced by Chikungunya virus infection is associated with interleukin-6 and granulocyte macrophage colony-stimulating factor. J Infect Dis (2011) 2.69
Reemergence of chikungunya virus. J Virol (2014) 2.11
Arthritogenic alphaviruses--an overview. Nat Rev Rheumatol (2012) 1.87
Chikungunya virus-associated long-term arthralgia: a 36-month prospective longitudinal study. PLoS Negl Trop Dis (2013) 1.86
Unconventional repertoire profile is imprinted during acute chikungunya infection for natural killer cells polarization toward cytotoxicity. PLoS Pathog (2011) 1.81
Chikungunya virus and prospects for a vaccine. Expert Rev Vaccines (2012) 1.69
Chikungunya fever: a clinical and virological investigation of outpatients on Reunion Island, South-West Indian Ocean. PLoS Negl Trop Dis (2013) 1.49
A mouse model of chikungunya virus-induced musculoskeletal inflammatory disease: evidence of arthritis, tenosynovitis, myositis, and persistence. Am J Pathol (2010) 1.48
Chikungunya disease: infection-associated markers from the acute to the chronic phase of arbovirus-induced arthralgia. PLoS Negl Trop Dis (2012) 1.42
Early appearance of neutralizing immunoglobulin G3 antibodies is associated with chikungunya virus clearance and long-term clinical protection. J Infect Dis (2012) 1.36
The acute phase of Chikungunya virus infection in humans is associated with strong innate immunity and T CD8 cell activation. J Infect Dis (2010) 1.29
Chikungunya virus infection. Curr Infect Dis Rep (2011) 1.27
Chronic joint disease caused by persistent Chikungunya virus infection is controlled by the adaptive immune response. J Virol (2013) 1.26
Chikungunya triggers an autophagic process which promotes viral replication. Virol J (2011) 1.26
ISG15 is critical in the control of Chikungunya virus infection independent of UbE1L mediated conjugation. PLoS Pathog (2011) 1.26
Perceived morbidity and community burden after a Chikungunya outbreak: the TELECHIK survey, a population-based cohort study. BMC Med (2011) 1.24
Specific management of post-chikungunya rheumatic disorders: a retrospective study of 159 cases in Reunion Island from 2006-2012. PLoS Negl Trop Dis (2015) 1.24
Chikungunya viral arthritis in the United States: a mimic of seronegative rheumatoid arthritis. Arthritis Rheumatol (2015) 1.19
Chikungunya virus neutralization antigens and direct cell-to-cell transmission are revealed by human antibody-escape mutants. PLoS Pathog (2011) 1.16
Viperin restricts chikungunya virus replication and pathology. J Clin Invest (2012) 1.16
Interferon response factors 3 and 7 protect against Chikungunya virus hemorrhagic fever and shock. J Virol (2012) 1.12
Arthritogenic alphaviral infection perturbs osteoblast function and triggers pathologic bone loss. Proc Natl Acad Sci U S A (2014) 1.10
Gene profiling of Chikungunya virus arthritis in a mouse model reveals significant overlap with rheumatoid arthritis. Arthritis Rheum (2012) 1.10
How many patients with post-chikungunya chronic inflammatory rheumatism can we expect in the new endemic areas of Latin America? Rheumatol Int (2015) 1.07
Predictors of Chikungunya rheumatism: a prognostic survey ancillary to the TELECHIK cohort study. Arthritis Res Ther (2013) 1.05
Deliberate attenuation of chikungunya virus by adaptation to heparan sulfate-dependent infectivity: a model for rational arboviral vaccine design. PLoS Negl Trop Dis (2014) 1.02
Multiple immune factors are involved in controlling acute and chronic chikungunya virus infection. PLoS Negl Trop Dis (2014) 1.01
Deciphering the protective role of adaptive immunity to CHIKV/IRES a novel candidate vaccine against Chikungunya in the A129 mouse model. Vaccine (2013) 0.99
Protective and Pathogenic Responses to Chikungunya Virus Infection. Curr Trop Med Rep (2015) 0.99
A novel poxvirus-based vaccine, MVA-CHIKV, is highly immunogenic and protects mice against chikungunya infection. J Virol (2014) 0.97
Detection of chikungunya virus antigen by a novel rapid immunochromatographic test. J Clin Microbiol (2014) 0.96
Animal Models of Chikungunya Virus Infection and Disease. J Infect Dis (2016) 0.96
NK cells: immune cross-talk and therapeutic implications. Immunotherapy (2011) 0.96
A chimeric vesiculo/alphavirus is an effective alphavirus vaccine. J Virol (2012) 0.95
Differential unfolded protein response during Chikungunya and Sindbis virus infection: CHIKV nsP4 suppresses eIF2α phosphorylation. Virol J (2013) 0.94
A neutralizing monoclonal antibody targeting the acid-sensitive region in chikungunya virus E2 protects from disease. PLoS Negl Trop Dis (2013) 0.94
A single-amino-acid polymorphism in Chikungunya virus E2 glycoprotein influences glycosaminoglycan utilization. J Virol (2013) 0.92
Both viremia and cytokine levels associate with the lack of severe disease in secondary dengue 1 infection among adult Chinese patients. PLoS One (2010) 0.92
Antiviral perspectives for chikungunya virus. Biomed Res Int (2014) 0.92
Comparative pathogenesis of epidemic and enzootic Chikungunya viruses in a pregnant Rhesus macaque model. Am J Trop Med Hyg (2010) 0.92
Caribbean and La Réunion Chikungunya Virus Isolates Differ in Their Capacity To Induce Proinflammatory Th1 and NK Cell Responses and Acute Joint Pathology. J Virol (2015) 0.91
Genetic ablation of arginase 1 in macrophages and neutrophils enhances clearance of an arthritogenic alphavirus. J Immunol (2012) 0.91
Assay optimization for molecular detection of Zika virus. Bull World Health Organ (2016) 0.90
Chikungunya viruses that escape monoclonal antibody therapy are clinically attenuated, stable, and not purified in mosquitoes. J Virol (2014) 0.90
Xenosurveillance: a novel mosquito-based approach for examining the human-pathogen landscape. PLoS Negl Trop Dis (2015) 0.90
Chikungunya virus: epidemiology, replication, disease mechanisms, and prospective intervention strategies. J Clin Invest (2017) 0.89
Mutations in nsP1 and PE2 are critical determinants of Ross River virus-induced musculoskeletal inflammatory disease in a mouse model. Virology (2010) 0.87
A Systematic Meta-analysis of Immune Signatures in Patients With Acute Chikungunya Virus Infection. J Infect Dis (2015) 0.86
Critical role for bone marrow stromal antigen 2 in acute Chikungunya virus infection. J Gen Virol (2014) 0.86
Bindarit, an inhibitor of monocyte chemotactic protein synthesis, protects against bone loss induced by chikungunya virus infection. J Virol (2014) 0.86
Rainbow trout (Oncorhynchus mykiss) muscle satellite cells are targets of salmonid alphavirus infection. Vet Res (2016) 0.85
Molecular mechanisms involved in the pathogenesis of alphavirus-induced arthritis. Biomed Res Int (2013) 0.85
Combined miRNA and mRNA signature identifies key molecular players and pathways involved in chikungunya virus infection in human cells. PLoS One (2013) 0.84
Residue 82 of the Chikungunya virus E2 attachment protein modulates viral dissemination and arthritis in mice. J Virol (2014) 0.84
Dendritic cell immunoreceptor regulates Chikungunya virus pathogenesis in mice. J Virol (2013) 0.84
A Rodent Model of Chikungunya Virus Infection in RAG1 -/- Mice, with Features of Persistence, for Vaccine Safety Evaluation. PLoS Negl Trop Dis (2015) 0.84
First Chikungunya Outbreak in Suriname; Clinical and Epidemiological Features. PLoS Negl Trop Dis (2016) 0.84
Mutations conferring a noncytotoxic phenotype on chikungunya virus replicons compromise enzymatic properties of nonstructural protein 2. J Virol (2014) 0.83
Chikungunya Virus Infection: An Update on Joint Manifestations and Management. Rambam Maimonides Med J (2016) 0.82
Macrophage migration inhibitory factor receptor CD74 mediates alphavirus-induced arthritis and myositis in murine models of alphavirus infection. Arthritis Rheum (2013) 0.82
Identification of novel compounds inhibiting chikungunya virus-induced cell death by high throughput screening of a kinase inhibitor library. PLoS Negl Trop Dis (2013) 0.82
Mouse macrophage innate immune response to Chikungunya virus infection. Virol J (2012) 0.81
Neuropathogenesis of Chikungunya infection: astrogliosis and innate immune activation. J Neurovirol (2015) 0.81
Deciphering the differential response of two human fibroblast cell lines following Chikungunya virus infection. Virol J (2012) 0.81
Comprehensive proteomic analysis of white blood cells from chikungunya fever patients of different severities. J Transl Med (2014) 0.81
Identical strength of the T cell responses against E2, nsP1 and capsid CHIKV proteins in recovered and chronic patients after the epidemics of 2005-2006 in La Reunion Island. PLoS One (2013) 0.81
A tyrosine-to-histidine switch at position 18 of the Ross River virus E2 glycoprotein is a determinant of virus fitness in disparate hosts. J Virol (2013) 0.80
Expanding regulatory T cells alleviates chikungunya virus-induced pathology in mice. J Virol (2015) 0.80
Chikungunya fever: focus on peripheral markers of pathogenesis. J Infect Dis (2011) 0.80
Attenuating mutations in nsP1 reveal tissue-specific mechanisms for control of Ross River virus infection. J Virol (2014) 0.80
A Role for RNA Viruses in the Pathogenesis of Burkitt's Lymphoma: The Need for Reappraisal. Adv Hematol (2011) 0.80
Infection of myofibers contributes to increased pathogenicity during infection with an epidemic strain of chikungunya virus. J Virol (2013) 0.79
Characterization of a Novel Human-Specific STING Agonist that Elicits Antiviral Activity Against Emerging Alphaviruses. PLoS Pathog (2015) 0.79
Nonhuman Primate Models of Chikungunya Virus Infection and Disease (CHIKV NHP Model). Pathogens (2015) 0.78
Crystal structure of aura virus capsid protease and its complex with dioxane: new insights into capsid-glycoprotein molecular contacts. PLoS One (2012) 0.78
Phenotypic and functional analyses of NK and NKT-like populations during the early stages of chikungunya infection. Front Microbiol (2015) 0.78
Mechanism and role of MCP-1 upregulation upon chikungunya virus infection in human peripheral blood mononuclear cells. Sci Rep (2016) 0.78
Regulation of Viral Replication, Apoptosis and Pro-Inflammatory Responses by 17-AAG during Chikungunya Virus Infection in Macrophages. Viruses (2017) 0.77
Dysregulated TGF-β Production Underlies the Age-Related Vulnerability to Chikungunya Virus. PLoS Pathog (2016) 0.77
A potent neutralizing IgM mAb targeting the N218 epitope on E2 protein protects against Chikungunya virus pathogenesis. MAbs (2015) 0.77
CD8+ T cells control Ross River virus infection in musculoskeletal tissues of infected mice. J Immunol (2014) 0.77
Myeloid Cell Arg1 Inhibits Control of Arthritogenic Alphavirus Infection by Suppressing Antiviral T Cells. PLoS Pathog (2015) 0.77
Association of HLA class-I and inhibitory KIR genotypes in Gabonese patients infected by Chikungunya or Dengue type-2 viruses. PLoS One (2014) 0.77
Longitudinal Analysis of Natural Killer Cells in Dengue Virus-Infected Patients in Comparison to Chikungunya and Chikungunya/Dengue Virus-Infected Patients. PLoS Negl Trop Dis (2016) 0.77
Pathogenic Chikungunya Virus Evades B Cell Responses to Establish Persistence. Cell Rep (2016) 0.76
Detection of Persistent Chikungunya Virus RNA but not Infectious Virus in Experimental Vertical Transmission in Aedes aegypti from Malaysia. Am J Trop Med Hyg (2015) 0.76
Chikungunya vaccines in development. Hum Vaccin Immunother (2016) 0.76
Methotrexate treatment causes early onset of disease in a mouse model of Ross River virus-induced inflammatory disease through increased monocyte production. PLoS One (2013) 0.76
Simultaneous detection of chikungunya virus, dengue virus and human pathogenic Leptospira genomes using a multiplex TaqMan® assay. BMC Microbiol (2017) 0.75
Attenuated and vectored vaccines protect nonhuman primates against Chikungunya virus. JCI Insight (2017) 0.75
The neutralizing role of IgM during early Chikungunya virus infection. PLoS One (2017) 0.75
RNA-Seq analysis of chikungunya virus infection and identification of granzyme A as a major promoter of arthritic inflammation. PLoS Pathog (2017) 0.75
Long-Term Arthralgia after Mayaro Virus Infection Correlates with Sustained Pro-inflammatory Cytokine Response. PLoS Negl Trop Dis (2015) 0.75
Molecular Virologic and Clinical Characteristics of a Chikungunya Fever Outbreak in La Romana, Dominican Republic, 2014. PLoS Negl Trop Dis (2016) 0.75
Lipopolysaccharide inhibits Sindbis virus-induced IP-10 release in human peripheral blood mononuclear cells. Viral Immunol (2011) 0.75
Neutralization activity of patient sera collected during the 2008-2009 Chikungunya outbreak in Thailand. J Clin Microbiol (2014) 0.75
Envelope specific T cell responses & cytokine profiles in chikungunya patients hospitalized with different clinical presentations. Indian J Med Res (2015) 0.75
Closing the gap between viral and noninfectious arthritis. Proc Natl Acad Sci U S A (2014) 0.75
Post-treatment HIV-1 controllers with a long-term virological remission after the interruption of early initiated antiretroviral therapy ANRS VISCONTI Study. PLoS Pathog (2013) 6.14
Superior control of HIV-1 replication by CD8+ T cells is reflected by their avidity, polyfunctionality, and clonal turnover. J Exp Med (2007) 5.58
Towards an HIV cure: a global scientific strategy. Nat Rev Immunol (2012) 5.52
Development of a TaqMan RT-PCR assay without RNA extraction step for the detection and quantification of African Chikungunya viruses. J Virol Methods (2004) 4.18
The EUROclass trial: defining subgroups in common variable immunodeficiency. Blood (2007) 4.14
Explosion of tuberculin-specific Th1-responses induces immune restoration syndrome in tuberculosis and HIV co-infected patients. AIDS (2006) 3.82
Decreased atherosclerotic lesion formation in CX3CR1/apolipoprotein E double knockout mice. Circulation (2003) 3.55
CX3CR1-dependent subretinal microglia cell accumulation is associated with cardinal features of age-related macular degeneration. J Clin Invest (2007) 3.39
Autophagy is involved in T cell death after binding of HIV-1 envelope proteins to CXCR4. J Clin Invest (2006) 3.34
A patient with HIV-1 superinfection. N Engl J Med (2002) 2.93
HIV infection rapidly induces and maintains a substantial suppression of thymocyte proliferation. Immunity (2004) 2.86
Prophylaxis and therapy for Chikungunya virus infection. J Infect Dis (2009) 2.54
Chikungunya infection: an emerging rheumatism among travelers returned from Indian Ocean islands. Report of 47 cases. Medicine (Baltimore) (2007) 2.48
Accelerated immune senescence and HIV-1 infection. Exp Gerontol (2007) 2.41
The immune paradox of sarcoidosis and regulatory T cells. J Exp Med (2006) 2.35
Antigen sensitivity is a major determinant of CD8+ T-cell polyfunctionality and HIV-suppressive activity. Blood (2009) 2.33
Distinct genetic loci control plasma HIV-RNA and cellular HIV-DNA levels in HIV-1 infection: the ANRS Genome Wide Association 01 study. PLoS One (2008) 2.14
Barriers to a cure for HIV: new ways to target and eradicate HIV-1 reservoirs. Lancet (2013) 2.11
Distinct time effects of vaccination on long-term proliferative and IFN-gamma-producing T cell memory to smallpox in humans. J Exp Med (2004) 2.08
Combination of HIV-1-specific CD4 Th1 cell responses and IgG2 antibodies is the best predictor for persistence of long-term nonprogression. J Infect Dis (2005) 2.03
Low T cell responses to human herpesvirus 8 in patients with AIDS-related and classic Kaposi sarcoma. J Infect Dis (2006) 2.02
Global natural regulatory T cell depletion in active systemic lupus erythematosus. J Immunol (2005) 2.00
Infections in 252 patients with common variable immunodeficiency. Clin Infect Dis (2008) 1.93
Profound coordinated alterations of intratumoral NK cell phenotype and function in lung carcinoma. Cancer Res (2011) 1.91
PD-1 expression on human CD8 T cells depends on both state of differentiation and activation status. AIDS (2007) 1.88
Clinical burden of chikungunya virus infection. Lancet Infect Dis (2008) 1.87
Arthritogenic alphaviruses--an overview. Nat Rev Rheumatol (2012) 1.87
Chikungunya virus, Cameroon, 2006. Emerg Infect Dis (2007) 1.87
Treatment of acute uncomplicated falciparum malaria with artemether-lumefantrine in nonimmune populations: a safety, efficacy, and pharmacokinetic study. Am J Trop Med Hyg (2008) 1.83
Evidence of premature immune aging in patients thymectomized during early childhood. J Clin Invest (2009) 1.81
Unconventional repertoire profile is imprinted during acute chikungunya infection for natural killer cells polarization toward cytotoxicity. PLoS Pathog (2011) 1.81
CMV drives clonal expansion of NKG2C+ NK cells expressing self-specific KIRs in chronic hepatitis patients. Eur J Immunol (2011) 1.81
Impact of therapeutic immunization on HIV-1 viremia after discontinuation of antiretroviral therapy initiated during acute infection. J Infect Dis (2005) 1.80
NK-cell reconstitution after haploidentical hematopoietic stem-cell transplantations: immaturity of NK cells and inhibitory effect of NKG2A override GvL effect. Blood (2005) 1.78
Chikungunya virus strains, Reunion Island outbreak. Emerg Infect Dis (2006) 1.73
NK cytotoxicity against CD4+ T cells during HIV-1 infection: a gp41 peptide induces the expression of an NKp44 ligand. Proc Natl Acad Sci U S A (2005) 1.67
Human NK cells display major phenotypic and functional changes over the life span. Aging Cell (2010) 1.65
A dendritic cell-based vaccine elicits T cell responses associated with control of HIV-1 replication. Sci Transl Med (2013) 1.62
Activation of complement in the central nervous system: roles in neurodegeneration and neuroprotection. Ann N Y Acad Sci (2003) 1.60
Active infection of human blood monocytes by Chikungunya virus triggers an innate immune response. J Immunol (2010) 1.60
Phenotype and function of natural killer cells in systemic lupus erythematosus: excess interferon-γ production in patients with active disease. Arthritis Rheum (2011) 1.59
NK cell terminal differentiation: correlated stepwise decrease of NKG2A and acquisition of KIRs. PLoS One (2010) 1.59
Dengue type 3 virus, Saint Martin, 2003-2004. Emerg Infect Dis (2005) 1.57
High cytotoxic and specific migratory potencies of senescent CD8+ CD57+ cells in HIV-infected and uninfected individuals. J Immunol (2006) 1.55
Chikungunya virus and the mosquito vector Aedes aegypti in New Caledonia (South Pacific Region). Vector Borne Zoonotic Dis (2012) 1.51
Toscana virus and acute meningitis, France. Emerg Infect Dis (2005) 1.49
Old age and anti-cytomegalovirus immunity are associated with altered T-cell reconstitution in HIV-1-infected patients. AIDS (2011) 1.47
Low titers of serum antibodies inhibiting hemagglutination predict fatal fulminant influenza A(H1N1) 2009 infection. Am J Respir Crit Care Med (2014) 1.45
Chikungunya fever: CNS infection and pathologies of a re-emerging arbovirus. Prog Neurobiol (2009) 1.44
Chikungunya virus infection of corneal grafts. J Infect Dis (2012) 1.44
Antibodies to conserved epitopes of the HIV-1 envelope in sera from long-term non-progressors: prevalence and association with neutralizing activity. AIDS (2006) 1.43
Repertoire, diversity, and differentiation of specific CD8 T cells are associated with immune protection against human cytomegalovirus disease. J Exp Med (2005) 1.43
Aedes albopictus mosquito: the main vector of the 2007 Chikungunya outbreak in Gabon. PLoS One (2009) 1.43
Circulation of Chikungunya virus in Gabon, 2006-2007. J Med Virol (2008) 1.40
Modulation of interleukin-7 receptor expression characterizes differentiation of CD8 T cells specific for HIV, EBV and CMV. AIDS (2005) 1.40
B-cell and T-cell phenotypes in CVID patients correlate with the clinical phenotype of the disease. J Clin Immunol (2010) 1.39
Escape from highly effective public CD8+ T-cell clonotypes by HIV. Blood (2011) 1.39
Vector competence of some French Culex and Aedes mosquitoes for West Nile virus. Vector Borne Zoonotic Dis (2008) 1.39
Regulation by complement C3a and C5a anaphylatoxins of cytokine production in human umbilical vein endothelial cells. FASEB J (2003) 1.38
Correlation between breadth of memory HIV-specific cytotoxic T cells, viral load and disease progression in HIV infection. AIDS (2002) 1.35
Chikungunya virus mobilizes the apoptotic machinery to invade host cell defenses. FASEB J (2010) 1.34
Tuberculosis-associated immune restoration syndrome in HIV-1-infected patients involves tuberculin-specific CD4 Th1 cells and KIR-negative gammadelta T cells. J Immunol (2009) 1.33
High efficiency of temperate Aedes albopictus to transmit chikungunya and dengue viruses in the Southeast of France. PLoS One (2013) 1.33
Immune responses driven by protective human leukocyte antigen alleles from long-term nonprogressors are associated with low HIV reservoir in central memory CD4 T cells. Clin Infect Dis (2012) 1.32
Mekong malaria. II. Update of malaria, multi-drug resistance and economic development in the Mekong region of Southeast Asia. Southeast Asian J Trop Med Public Health (2003) 1.31
40 nm, but not 750 or 1,500 nm, nanoparticles enter epidermal CD1a+ cells after transcutaneous application on human skin. J Invest Dermatol (2006) 1.31
Helminth infections are associated with protection from cerebral malaria and increased nitrogen derivatives concentrations in Thailand. Am J Trop Med Hyg (2002) 1.31
The multiple roles of the innate immune system in the regulation of apoptosis and inflammation in the brain. J Neuropathol Exp Neurol (2009) 1.30
Chikungunya triggers an autophagic process which promotes viral replication. Virol J (2011) 1.26
Detection of antibodies to deiminated recombinant rat filaggrin by enzyme-linked immunosorbent assay: a highly effective test for the diagnosis of rheumatoid arthritis. Arthritis Rheum (2002) 1.26
Imported Mayaro virus infection in the Netherlands. J Infect (2010) 1.26
Presence of functional TLR2 and TLR4 on human adipocytes. Histochem Cell Biol (2006) 1.25
Identification of a cellular ligand for the natural cytotoxicity receptor NKp44. Blood (2013) 1.25
HIV disease progression despite suppression of viral replication is associated with exhaustion of lymphopoiesis. Blood (2011) 1.25
CD56brightCD16+ NK cells: a functional intermediate stage of NK cell differentiation. J Immunol (2011) 1.24
Chagas disease, France. Emerg Infect Dis (2008) 1.23
Genetic diversity of Toscana virus. Emerg Infect Dis (2009) 1.23
Longitudinal analysis of the human antibody response to Chikungunya virus infection: implications for serodiagnosis and vaccine development. J Virol (2012) 1.21
Polymorphism in the microglial cell-mobilizing CX3CR1 gene is associated with survival in patients with glioblastoma. J Clin Oncol (2008) 1.21
Human endogenous retrovirus (HERV)-W ENV and GAG proteins: physiological expression in human brain and pathophysiological modulation in multiple sclerosis lesions. J Neurovirol (2005) 1.19
Immune reconstitution after a decade of combined antiretroviral therapies for human immunodeficiency virus. Trends Immunol (2011) 1.19
Human endosialin (tumor endothelial marker 1) is abundantly expressed in highly malignant and invasive brain tumors. J Neuropathol Exp Neurol (2004) 1.19