Published in J Clin Invest on June 01, 1991
Sympathetic neural mechanisms in obstructive sleep apnea. J Clin Invest (1995) 6.64
NADPH oxidase-derived superoxide anion mediates angiotensin II-enhanced carotid body chemoreceptor sensitivity in heart failure rabbits. Cardiovasc Res (2007) 1.56
Sympathetic neural overactivity in healthy humans after prolonged exposure to hypobaric hypoxia. J Physiol (2003) 1.51
Chemoreceptor hypersensitivity, sympathetic excitation, and overexpression of ASIC and TASK channels before the onset of hypertension in SHR. Circ Res (2009) 1.46
Chronic hypoxia increases blood pressure and noradrenaline spillover in healthy humans. J Physiol (2003) 1.32
Interaction of chemoreceptor and baroreceptor reflexes by hypoxia and hypercapnia - a mechanism for promoting hypertension in obstructive sleep apnoea. J Physiol (2005) 1.26
Peripheral chemoreflex and baroreflex interactions in cardiovascular regulation in humans. J Physiol (2003) 1.22
Obstructive sleep apnea, cardiovascular disease, and pulmonary hypertension. Proc Am Thorac Soc (2008) 1.22
Cerebral hemodynamic changes during intensive care of preterm infants. Pediatrics (2008) 1.22
Central CO2 chemoreception and integrated neural mechanisms of cardiovascular and respiratory control. J Appl Physiol (1985) (2010) 1.20
Carotid body function in heart failure. Respir Physiol Neurobiol (2007) 1.14
Baroreflex-induced sympathetic activation does not alter cerebrovascular CO2 responsiveness in humans. J Physiol (2003) 1.12
Chemoreflex function in heart failure. Heart Fail Rev (2000) 1.07
Obstructive sleep apnea and insight into mechanisms of sympathetic overactivity. J Clin Invest (2014) 1.03
Effects of direct cedrol inhalation into the lower airway on autonomic nervous activity in totally laryngectomized subjects. Br J Clin Pharmacol (2007) 0.96
Revelations about carotid body function through its pathological role in resistant hypertension. Curr Hypertens Rep (2013) 0.94
Consequences of peripheral chemoreflex inhibition with low-dose dopamine in humans. J Physiol (2014) 0.94
The Walter B. Cannon Memorial Award Lecture, 2009. Physiology in perspective: The wisdom of the body. In search of autonomic balance: the good, the bad, and the ugly. Am J Physiol Regul Integr Comp Physiol (2010) 0.94
Autonomic dysfunction in patients with chronic obstructive pulmonary disease (COPD). J Thorac Dis (2010) 0.92
Clinical neurocardiology defining the value of neuroscience-based cardiovascular therapeutics. J Physiol (2016) 0.92
Restrictive ventilatory impairment and arterial oxygenation characterize rest and exercise ventilation in patients after fontan operation. Pediatr Cardiol (2004) 0.91
Obstructive sleep apnea: the new cardiovascular disease. Part I: Obstructive sleep apnea and the pathogenesis of vascular disease. Heart Fail Rev (2008) 0.90
Translational neurocardiology: preclinical models and cardioneural integrative aspects. J Physiol (2016) 0.89
Cardiac sympathetic modulation in response to apneas/hypopneas through heart rate variability analysis. PLoS One (2014) 0.88
Obstructive sleep apnea is associated with increased chemoreflex sensitivity in patients with metabolic syndrome. Sleep (2013) 0.88
Chemoreflexes, sleep apnea, and sympathetic dysregulation. Curr Hypertens Rep (2014) 0.86
Paris Prospective Study III: a study of novel heart rate parameters, baroreflex sensitivity and risk of sudden death. Eur J Epidemiol (2011) 0.86
Peripheral chemoreflex inhibition with low-dose dopamine: New insight into mechanisms of extreme apnea. Am J Physiol Regul Integr Comp Physiol (2015) 0.86
Sympathetic withdrawal augments cerebral blood flow during acute hypercapnia in sleeping lambs. Sleep (2008) 0.86
Pulse transit time in screening sleep disordered breathing in an elderly population: the PROOF-SYNAPSE study. Sleep (2011) 0.85
Effect of bilateral carotid body resection on cardiac baroreflex control of blood pressure during hypoglycemia. Hypertension (2015) 0.85
Sleep disorders in chronic obstructive pulmonary disease: etiology, impact, and management. J Clin Sleep Med (2015) 0.84
Cardiovascular and respiratory effect of yogic slow breathing in the yoga beginner: what is the best approach? Evid Based Complement Alternat Med (2013) 0.84
Baroreflex contribution to blood pressure and heart rate oscillations: time scales, time-variant characteristics and nonlinearities. Philos Trans A Math Phys Eng Sci (2009) 0.83
The control of adrenergic function in heart failure: therapeutic intervention. Heart Fail Rev (2000) 0.83
Acute Response to Unilateral Unipolar Electrical Carotid Sinus Stimulation in Patients With Resistant Arterial Hypertension. Hypertension (2016) 0.81
Central sleep apnea indicates autonomic dysfunction in asymptomatic carotid stenosis: a potential marker of cerebrovascular and cardiovascular risk. Sleep (2010) 0.81
Hemodynamic and ventilatory response to different levels of hypoxia and hypercapnia in carotid body-denervated rats. Clinics (Sao Paulo) (2013) 0.81
Mild central chemoreflex activation does not alter arterial baroreflex function in healthy humans. J Physiol (2007) 0.81
Role of Chemoreceptor Activation in Hemodynamic Responses to Electrical Stimulation of the Carotid Sinus in Conscious Rats. Hypertension (2015) 0.80
Role of the carotid body chemoreceptors in baroreflex control of blood pressure during hypoglycaemia in humans. Exp Physiol (2014) 0.80
Chronic Interactions Between Carotid Baroreceptors and Chemoreceptors in Obesity Hypertension. Hypertension (2016) 0.80
Pathogenesis of cognitive dysfunction in patients with obstructive sleep apnea: a hypothesis with emphasis on the nucleus tractus solitarius. Sleep Disord (2012) 0.80
Interaction between central-peripheral chemoreflexes and cerebro-cardiovascular control. Clin Auton Res (2005) 0.79
Modulation of peripheral chemoreflex by neurohumoral adaptations after kidney transplantation. Eur J Med Res (2010) 0.79
Dose-dependent effect of dobutamine on chemoreflex activity in healthy volunteers. Br J Clin Pharmacol (2006) 0.79
Effects of body position on the ventilatory response to hypercapnia. Eur J Med Res (2009) 0.78
Autonomic cardiovascular response to acute hypoxia and passive head-up tilting in humans. Eur J Appl Physiol (2013) 0.78
Carotid body potentiation during chronic intermittent hypoxia: implication for hypertension. Front Physiol (2014) 0.78
Interindividual variability in the dose-specific effect of dopamine on carotid chemoreceptor sensitivity to hypoxia. J Appl Physiol (1985) (2015) 0.78
Cardiovascular Regulation in Obstructive Sleep Apnea. Drug Discov Today Dis Models (2011) 0.78
Effect of acute ozone induced airway inflammation on human sympathetic nerve traffic: a randomized, placebo controlled, crossover study. PLoS One (2011) 0.77
Baroreflex responsiveness during ventilatory acclimatization in humans. Am J Physiol Heart Circ Physiol (2008) 0.77
Chemoreflex physiology and implications for sleep apnoea: insights from studies in humans. Exp Physiol (2014) 0.77
ASICs and cardiovascular homeostasis. Neuropharmacology (2015) 0.76
Systemic hypoxia affects cardiac autonomic activity and vascular hemodynamic control modulated by physical stimulation. Eur J Appl Physiol (2009) 0.76
Age-related reflex responses from peripheral and central chemoreceptors in healthy men. Clin Auton Res (2014) 0.76
Baroreflex sensitivity in acute hypoxia and carbohydrate loading. Eur J Appl Physiol (2011) 0.75
Reductions in carotid chemoreceptor activity with low-dose dopamine improves baroreflex control of heart rate during hypoxia in humans. Physiol Rep (2016) 0.75
Intact blood pressure, but not sympathetic, responsiveness to sympathoexcitatory stimuli in a patient with unilateral carotid body resection. Physiol Rep (2017) 0.75
What Happens before Syncope? Study of the Time Frame Preceding Vasovagal Syncope. ISRN Cardiol (2011) 0.75
Contribution of Autonomic Reflexes to the Hyperadrenergic State in Heart Failure. Front Neurosci (2017) 0.75
Prevalence of obstructive sleep apnea in patients with chronic wounds. J Clin Sleep Med (2010) 0.75
Ventilatory responses to chemoreflex stimulation are not enhanced by angiotensin II in healthy humans. Auton Neurosci (2014) 0.75
Obesity, Hypoxemia, and Hypertension: Mechanistic Insights and Therapeutic Implications. Hypertension (2016) 0.75
Acute and chronic changes in baroreflex sensitivity in hypobaric vs. normobaric hypoxia. Eur J Appl Physiol (2017) 0.75
Somatosensory, proprioceptive, and sympathetic activity in human peripheral nerves. Physiol Rev (1979) 7.25
Microneurographic studies of the mechanisms of sympathetic nerve responses to static exercise in humans. Circ Res (1985) 3.88
Contrasting effects of hypoxia and hypercapnia on ventilation and sympathetic activity in humans. J Appl Physiol (1985) (1989) 2.04
Effect of carotid endarterectomy on carotid chemoreceptor and baroreceptor function in man. N Engl J Med (1970) 1.97
Influence of ventilation and hypocapnia on sympathetic nerve responses to hypoxia in normal humans. J Appl Physiol (1985) (1989) 1.91
The effect of noradrenaline infusion on the relation between pulmonary ventilation and the alveolar PO2 and PCO2 in man. Ann N Y Acad Sci (1963) 1.76
Potentiation of sympathetic nerve responses to hypoxia in borderline hypertensive subjects. Hypertension (1988) 1.56
Effect of bilateral carotid-body resection on ventilatory control at rest and during exercise in man. N Engl J Med (1971) 1.55
The role of the solitary and paramedian reticular nuclei in mediating cardiovascular reflex responses from carotid baro- and chemoreceptors. J Physiol (1972) 1.53
Interaction of baroreceptor and chemoreceptor reflexes. Modulation of the chemoreceptor reflex by changes in baroreceptor activity. J Clin Invest (1974) 1.50
Dynamic respiratory response to abrupt change of inspired CO2 at normal and high PO2. J Appl Physiol (1973) 1.28
Influence of carotid baroreceptors on vascular responses to carotid chemoreceptor stimulation in the dog. Circ Res (1975) 1.27
Effect of baroreceptor activity on ventilatory response to chemoreceptor stimulation. J Appl Physiol (1975) 1.24
Interplay among carotid sinus, cardiopulmonary, and carotid body reflexes in dogs. Am J Physiol (1976) 1.22
Reflex vascular responses to stimulation of chemoreceptors with nicotine and cyanide. Activation of adrenergic constriction in muscle and noncholinergic dilatation in dog's paw. Circ Res (1970) 1.12
Cardiovascular responses to hypoxia and hypercapnia in barodenervated rats. J Appl Physiol (1985) (1990) 1.00
Relative contribution of aortic and carotid baroreflexes to heart rate control in man during steady state and dynamic increases in arterial pressure. J Clin Invest (1985) 0.92
Sympathetic neural mechanisms in obstructive sleep apnea. J Clin Invest (1995) 6.64
Sympathetic-nerve activity during sleep in normal subjects. N Engl J Med (1993) 5.85
Microneurographic studies of the mechanisms of sympathetic nerve responses to static exercise in humans. Circ Res (1985) 3.88
Hyperinsulinemia produces both sympathetic neural activation and vasodilation in normal humans. J Clin Invest (1991) 3.49
Receptor-mediated regional sympathetic nerve activation by leptin. J Clin Invest (1997) 2.98
Relationship between spectral components of cardiovascular variabilities and direct measures of muscle sympathetic nerve activity in humans. Circulation (1997) 2.49
Effects of the cold pressor test on muscle sympathetic nerve activity in humans. Hypertension (1987) 2.46
The Bezold-Jarisch reflex revisited: clinical implications of inhibitory reflexes originating in the heart. J Am Coll Cardiol (1983) 2.39
Elevated sympathetic nerve activity in borderline hypertensive humans. Evidence from direct intraneural recordings. Hypertension (1989) 2.21
Direct evidence from intraneural recordings for increased central sympathetic outflow in patients with heart failure. Circulation (1986) 2.19
Contrasting effects of hypoxia and hypercapnia on ventilation and sympathetic activity in humans. J Appl Physiol (1985) (1989) 2.04
Differential control of heart rate and sympathetic nerve activity during dynamic exercise. Insight from intraneural recordings in humans. J Clin Invest (1987) 1.93
Selective beta-1 receptor blockade with oral practolol in man. A dose-related phenomenon. J Clin Invest (1975) 1.91
Influence of ventilation and hypocapnia on sympathetic nerve responses to hypoxia in normal humans. J Appl Physiol (1985) (1989) 1.91
Recommendations for human blood pressure determination by sphygmomanometers. Subcommittee of the AHA Postgraduate Education Committee. Circulation (1980) 1.90
A molecular component of the arterial baroreceptor mechanotransducer. Neuron (1998) 1.87
Effects of heart failure on baroreflex control of sympathetic neural activity. Am J Cardiol (1992) 1.84
Interactions between the melanocortin system and leptin in control of sympathetic nerve traffic. Hypertension (1999) 1.82
A simplified neck suction device for activation of carotid baroreceptors. J Lab Clin Med (1975) 1.82
Effects of adrenergic stimulation on ventilation in man. J Clin Invest (1972) 1.80
Augmented responses to vasoconstrictor stimuli in hypercholesterolemic and atherosclerotic monkeys. Circ Res (1984) 1.69
The role of low pressure baroreceptors in reflex vasoconstrictor responses in man. J Clin Invest (1972) 1.59
Tonic chemoreflex activation does not contribute to elevated muscle sympathetic nerve activity in heart failure. Circulation (1996) 1.57
Potentiation of sympathetic nerve responses to hypoxia in borderline hypertensive subjects. Hypertension (1988) 1.56
Interaction of baroreceptor and chemoreceptor reflexes. Modulation of the chemoreceptor reflex by changes in baroreceptor activity. J Clin Invest (1974) 1.50
Reflex control of the peripheral circulation. Prog Cardiovasc Dis (1976) 1.47
Risk stratification with pre-hospital discharge exercise technetium-99m sestamibi myocardial tomography in men after acute myocardial infarction. Am Heart J (1998) 1.42
Contrasting effects of static and pulsatile pressure on carotid baroreceptor activity in dogs. Circ Res (1987) 1.39
Dickinson W. Richards Lecture: Circulatory adjustments to hypoxia. Circulation (1980) 1.38
Pathophysiologic levels of atrial natriuretic factor do not alter reflex sympathetic control: direct evidence from microneurographic studies in humans. J Am Coll Cardiol (1990) 1.37
Contrasting effects of digitalis and dobutamine on baroreflex sympathetic control in normal humans. Circulation (1991) 1.37
Spatial and temporal heterogeneity of left ventricular perfusion in awake dogs. Am Heart J (1977) 1.33
Active reflex vasodilatation in man. Fed Proc (1967) 1.32
Coronary vasodilatation produced by dopamine after adrenergic blockade. J Pharmacol Exp Ther (1971) 1.32
Dissociation of sympathetic nerve activity in arm and leg muscle during mental stress. Hypertension (1987) 1.32
Sympathetic and cardiorenal actions of leptin. Hypertension (1997) 1.32
Sympathetic outflow to resting muscles during static handgrip and postcontraction muscle ischemia. Am J Physiol (1989) 1.31
Postexercise hypotension and sympathoinhibition in borderline hypertensive men. Hypertension (1989) 1.28
Localization of beta and gamma subunits of ENaC in sensory nerve endings in the rat foot pad. Brain Res (2000) 1.26
Coronary vascular responses to stimulation of chemoreceptors and baroreceptors: evidence for reflex activation of vagal cholinergic innervation. Circ Res (1972) 1.26
Carotid and cardiopulmonary baroreceptor control of splanchnic and forearm vascular resistance during venous pooling in man. J Physiol (1979) 1.25
Effect of baroreceptor activity on ventilatory response to chemoreceptor stimulation. J Appl Physiol (1975) 1.24
Neurocardiogenic syncope. N Engl J Med (1993) 1.22
Preferential distribution of inhibitory cardiac receptors with vagal afferents to the inferoposterior wall of the left ventricle activated during coronary occlusion in the dog. Circ Res (1978) 1.20
Abnormal vascular responses to exercise in patients with aortic stenosis. J Clin Invest (1973) 1.20
Effect of renal hypertension and left ventricular hypertrophy on the coronary circulation in dogs. Circ Res (1978) 1.18
Comparative changes in segmental vascular resistance in response to nerve stimulation and to norepinephrine. Circ Res (1966) 1.17
Nonuniform regional sympathetic nerve responses to hyperinsulinemia in rats. Am J Physiol (1993) 1.16
Sympathetic activation by hypoxia and hypercapnia--implications for sleep apnea. Clin Exp Hypertens A (1988) 1.16
Flow-mediated and reflex changes in large peripheral artery tone in humans. Circulation (1989) 1.16
Muscle sympathetic nerve responses to dynamic one-legged exercise: effect of body posture. Am J Physiol (1993) 1.16
Three dimensional geometry of acutely ischemic myocardium. Circulation (1975) 1.15
Nitric oxide as an autocrine regulator of sodium currents in baroreceptor neurons. Neuron (1998) 1.14
Reflex vascular responses to stimulation of chemoreceptors with nicotine and cyanide. Activation of adrenergic constriction in muscle and noncholinergic dilatation in dog's paw. Circ Res (1970) 1.12
Role of large arteries in regulation of cerebral blood flow in dogs. J Clin Invest (1978) 1.11
Correlation between echocardiographically demonstrated segmental dyskinesis and regional myocardial perfusion. Circulation (1975) 1.11
Hyperinsulinemia produces cardiac vagal withdrawal and nonuniform sympathetic activation in normal subjects. Am J Physiol (1999) 1.11
Arterial baroreflex control of sympathetic nerve activity during elevation of blood pressure in normal man: dominance of aortic baroreflexes. Circulation (1988) 1.10
The vasodilator action of insulin. Implications for the insulin hypothesis of hypertension. Hypertension (1993) 1.10
Increase in sympathetic activity with age. I. Role of impairment of arterial baroreflexes. Am J Physiol (1991) 1.10
Angiotensin II attenuates baroreflex control of heart rate and sympathetic activity. Am J Physiol (1984) 1.09
Differences in responses of saphenous and mesenteric veins to reflex stimuli. Am J Physiol (1970) 1.09
Central vagotonic effects of atropine modulate spectral oscillations of sympathetic nerve activity. Circulation (1998) 1.09
Intracerebroventricular insulin produces nonuniform regional increases in sympathetic nerve activity. Am J Physiol (1994) 1.09
Nongenomic effects of progesterone on human intestinal smooth muscle cells. Am J Physiol (1996) 1.07
Influence of cardiopulmonary vagal afferent activity on carotid chemoreceptor and baroreceptor reflexes in the dog. Circ Res (1975) 1.07
Total and regional cerebral blood flow measurement with 7-10-, 15-, 25-, and 50-mum microspheres. J Appl Physiol (1976) 1.07
Limitations of thallium-201 myocardial perfusion scintigrams. Circulation (1976) 1.07
Modulation of carotid baroreflex responsiveness in man: effects of posture and propranolol. J Appl Physiol (1976) 1.07
Ventricular syncope: is the heart a sensory organ? N Engl J Med (1989) 1.07
Renal sympathetic nerve activity is increased in obese Zucker rats. Hypertension (1995) 1.06
Interaction of cardiopulmonary and carotid baroreflex control of vascular resistance in humans. J Clin Invest (1985) 1.06
Oxygen-derived free radicals contribute to baroreceptor dysfunction in atherosclerotic rabbits. Circ Res (1996) 1.06
Recommendations for human blood pressure determination by sphygmomanometers. Subcommittee of the AHA Postgraduate Education Committee. Hypertension (1982) 1.05
Mechanical stimulation increases intracellular calcium concentration in nodose sensory neurons. Neuroscience (1995) 1.05
Evidence for cholinergically mediated vasodilation at the beginning of isometric exercise in humans. Circulation (1989) 1.05
The sympathetic system in hypertension. State-of-the-art review. Hypertension (1982) 1.05
Mental stress increases sympathetic nerve activity during sustained baroreceptor stimulation in humans. Hypertension (1991) 1.05
Mechanosensitive currents in putative aortic baroreceptor neurons in vitro. J Neurophysiol (1995) 1.04
The report of the American Heart Association task force on strategies to increase federal research funding. Circulation (1990) 1.03
Effects of alcohol on sympathetic activity, hemodynamics, and chemoreflex sensitivity. Hypertension (1997) 1.03
Central command increases sympathetic nerve activity during spontaneous locomotion in cats. Circ Res (1991) 1.03
Chemoreflexes--responses, interactions and implications for sleep apnea. Sleep (1993) 1.03