Published in J Clin Invest on June 01, 1991
RANTES and macrophage inflammatory protein 1 alpha induce the migration and activation of normal human eosinophil granulocytes. J Exp Med (1992) 3.25
Cytokines in asthma. Thorax (1999) 2.64
Binding to heparan sulfate or heparin enhances neutrophil responses to interleukin 8. Proc Natl Acad Sci U S A (1993) 2.45
Eosinophils: multifaceted biological properties and roles in health and disease. Immunol Rev (2011) 1.45
Eosinophil accumulation induced by human interleukin-8 in the guinea-pig in vivo. Immunology (1993) 1.23
Voltage-activated proton current in eosinophils from human blood. J Physiol (1996) 1.15
Recognition of fungal protease activities induces cellular activation and eosinophil-derived neurotoxin release in human eosinophils. J Immunol (2009) 0.97
Adenosine A3 receptors on human eosinophils mediate inhibition of degranulation and superoxide anion release. Br J Pharmacol (1999) 0.91
Alternaria fungus induces the production of GM-CSF, interleukin-6 and interleukin-8 and calcium signaling in human airway epithelium through protease-activated receptor 2. Int Arch Allergy Immunol (2012) 0.88
Protein kinase C activation inhibits eosinophil degranulation through stimulation of intracellular cAMP production. Br J Pharmacol (2004) 0.81
Cloning and functional expression of the canine anaphylatoxin C5a receptor. Evidence for high interspecies variability. Biochem J (1992) 0.81
A parallel signal-transduction pathway for eotaxin- and interleukin-5-induced eosinophil shape change. Immunology (2003) 0.80
Expression of human platelet-activating factor receptor gene in EoL-1 cells following butyrate-induced differentiation. Biochem J (1995) 0.78
A new generation of Ca2+ indicators with greatly improved fluorescence properties. J Biol Chem (1985) 90.20
Neutrophil-activating peptide-1/interleukin 8, a novel cytokine that activates neutrophils. J Clin Invest (1989) 10.59
Staurosporine, a potent inhibitor of phospholipid/Ca++dependent protein kinase. Biochem Biophys Res Commun (1986) 7.96
A new method for the purification of human eosinophils and neutrophils, and a comparison of the ability of these cells to damage schistosomula of Schistosoma mansoni. J Immunol (1979) 4.17
The eosinophilic leukocyte: structure and function. Adv Immunol (1986) 4.08
Synthesis and expression in Escherichia coli of the gene encoding monocyte-derived neutrophil-activating factor: biological equivalence between natural and recombinant neutrophil-activating factor. Proc Natl Acad Sci U S A (1988) 3.37
Platelet-activating factor. A potent chemotactic and chemokinetic factor for human eosinophils. J Clin Invest (1986) 2.90
Mechanism of neutrophil activation by NAF, a novel monocyte-derived peptide agonist. FASEB J (1988) 2.83
Regulation of human eosinophil viability, density, and function by granulocyte/macrophage colony-stimulating factor in the presence of 3T3 fibroblasts. J Exp Med (1987) 2.69
In vivo inflammatory activity of neutrophil-activating factor, a novel chemotactic peptide derived from human monocytes. Am J Pathol (1989) 2.37
Signal transduction and cytoskeletal activation in the neutrophil. Physiol Rev (1987) 2.34
Heterogeneity of human peripheral blood eosinophils: variability in cell density and cytotoxic ability in relation to the level and the origin of hypereosinophilia. Int Arch Allergy Appl Immunol (1983) 2.17
Protein kinase C phosphorylates human platelet inositol trisphosphate 5'-phosphomonoesterase, increasing the phosphatase activity. Cell (1986) 2.15
Human eosinophils have prolonged survival, enhanced functional properties, and become hypodense when exposed to human interleukin 3. J Clin Invest (1988) 2.15
Molecular cloning of the human eosinophil peroxidase. Evidence for the existence of a peroxidase multigene family. J Exp Med (1989) 1.83
1,2-Diacylglycerol and phorbol ester inhibit agonist-induced formation of inositol phosphates in human platelets: possible implications for negative feedback regulation of inositol phospholipid hydrolysis. Proc Natl Acad Sci U S A (1985) 1.73
Isolation of three separate anaphylatoxins from complement-activated human serum. Mol Cell Biochem (1981) 1.70
A diacylglycerol analogue reduces neuronal calcium currents independently of protein kinase C activation. Nature (1989) 1.58
GTP-binding proteins as possible targets for protein kinase C action. Trends Biochem Sci (1989) 1.55
The ECF-A tetrapeptides and histamine selectively enhance human eosinophil complement receptors. Nature (1977) 1.43
Human eosinophil peroxidase: purification and characterization. J Immunol (1985) 1.36
Molecular cloning of the human eosinophil-derived neurotoxin: a member of the ribonuclease gene family. Proc Natl Acad Sci U S A (1989) 1.35
Staurosporine inhibits protein kinase C and prevents phorbol ester-mediated leukotriene D4 receptor desensitization in RBL-1 cells. Mol Pharmacol (1988) 1.35
Stimulation of degranulation from human eosinophils by platelet-activating factor. J Immunol (1989) 1.32
Comparison of protein kinase C functional assays to clarify mechanisms of inhibitor action. Biochem Pharmacol (1988) 1.30
Human eosinophil cationic protein. Molecular cloning of a cytotoxin and helminthotoxin with ribonuclease activity. J Exp Med (1989) 1.29
Heterogeneity of human eosinophils. II. Variability of respiratory burst activity related to cell density. Clin Exp Immunol (1984) 1.28
The onset of the respiratory burst in human neutrophils. Real-time studies of H2O2 formation reveal a rapid agonist-induced transduction process. J Biol Chem (1987) 1.28
Role of a guanine nucleotide regulatory protein in the activation of phospholipase C by different chemoattractants. J Immunol (1987) 1.24
Eosinophil function and disorders. Adv Intern Med (1974) 1.22
Corresponding oscillations in neutrophil shape and filamentous actin content. J Biol Chem (1990) 1.22
Respiratory burst oscillations in human neutrophils and their correlation with fluctuations in apparent cell shape. J Biol Chem (1989) 1.21
Increased breakdown of phosphatidylinositol 4,5-bisphosphate is not an initiating factor for actin assembly in human neutrophils. J Biol Chem (1988) 1.16
Staurosporine inhibits the respiratory burst and induces exocytosis in human neutrophils. Biochem J (1989) 1.16
K-252a, a potent inhibitor of protein kinase C from microbial origin. J Antibiot (Tokyo) (1986) 1.12
The protein kinase inhibitor staurosporine, like phorbol esters, induces the association of protein kinase C with membranes. Biochem Biophys Res Commun (1988) 1.06
Enhanced chemiluminescent reactions catalyzed by horseradish peroxidase. Methods Enzymol (1986) 1.05
Acidic precursor revealed in human eosinophil granule major basic protein cDNA. J Exp Med (1988) 1.03
Complete dissociation between the activation of phosphoinositide turnover and of NADPH oxidase by formyl-methionyl-leucyl-phenylalanine in human neutrophils depleted of Ca2+ and primed by subthreshold doses of phorbol 12,myristate 13,acetate. Biochem Biophys Res Commun (1986) 1.02
Interleukin-5: an eosinophil growth and activation factor. Dev Biol Stand (1988) 0.96
Plasma membrane antigens on light density and activated human blood eosinophils. Clin Exp Immunol (1985) 0.96
The effect of a protein kinase C inhibitor, H-7, on human neutrophil oxidative burst and degranulation. J Leukoc Biol (1987) 0.95
Signal transduction in cells following binding of chemoattractants to membrane receptors. Virchows Arch B Cell Pathol Incl Mol Pathol (1988) 0.94
Functional studies on human peritoneal eosinophils. Infect Immun (1977) 0.94
Preferential human eosinophil chemotactic activity of the platelet-activating factor (PAF) 1-0-hexadecyl-2-acetyl-sn-glyceryl-3-phosphocholine (AGEPC). J Clin Immunol (1987) 0.92
Monoclonal antibodies to human eosinophil plasma membrane antigens enhance the secretion of eosinophil cationic protein. Clin Exp Immunol (1986) 0.90
Dissociation of the 47-kilodalton protein phosphorylation from degranulation and superoxide production in neutrophils. J Leukoc Biol (1988) 0.88
Staurosporine, a potent protein kinase C inhibitor, fails to inhibit 12-O-tetradecanoylphorbol-13-acetate-caused ornithine decarboxylase induction in isolated mouse epidermal cells. Biochem Biophys Res Commun (1987) 0.88
Utility of staurosporine in uncovering differences in the signal transduction pathways for superoxide production in neutrophils. Biochim Biophys Acta (1990) 0.87
Oscillatory motion in human neutrophils responding to chemotactic stimuli. Biochem Biophys Res Commun (1987) 0.87
Effect of an inhibitor of protein kinase C on human polymorphonuclear leukocyte degranulation. Biochem Biophys Res Commun (1987) 0.86
Characterization of platelet-activating factor-induced elevation of cytosolic free calcium concentration in eosinophils. FEBS Lett (1989) 0.85
Effects of platelet activating factor on the chemotaxis of normodense eosinophils from normal subjects. Biochem Biophys Res Commun (1987) 0.84
Phorbol ester-induced activation of protein kinase C leads to increased formation of diacylglycerol in human neutrophils. Exp Cell Res (1989) 0.84
The behavioural repertoire of neutrophils requires multiple signal transduction pathways. J Cell Sci (1988) 0.82
Paradoxical effects of retinal in neutrophil stimulation. J Biol Chem (1989) 0.82
Function and stimulus-specific effects of phorbol 12-myristate 13-acetate on human polymorphonuclear neutrophils: autoregulatory role for protein kinase C in signal transduction. Inflammation (1988) 0.81
Cellular models for the detection and evaluation of drugs that modulate human phagocyte activity. Experientia (1988) 0.81
Real-time models of morphogenetic processes. Experientia (1988) 0.77
Cytophilic IgE on human blood and tissue eosinophils. Int Arch Allergy Appl Immunol (1985) 0.77
The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1. Nature (1996) 9.25
International union of pharmacology. XXII. Nomenclature for chemokine receptors. Pharmacol Rev (2000) 7.17
Chemokine receptor specific for IP10 and mig: structure, function, and expression in activated T-lymphocytes. J Exp Med (1996) 6.36
Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation. Science (2000) 6.26
Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: the role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses. Biochem J (1993) 5.53
Structural determinants of phosphoinositide 3-kinase inhibition by wortmannin, LY294002, quercetin, myricetin, and staurosporine. Mol Cell (2000) 5.23
A novel neutrophil-activating factor produced by human mononuclear phagocytes. J Exp Med (1988) 4.86
The mechanism of protein secretion across membranes. Nature (1980) 4.72
Resolution of granules from rabbit heterophil leukocytes into distinct populations by zonal sedimentation. J Cell Biol (1969) 4.36
Solution structure and basis for functional activity of stromal cell-derived factor-1; dissociation of CXCR4 activation from binding and inhibition of HIV-1. EMBO J (1997) 4.04
CCR5 is characteristic of Th1 lymphocytes. Nature (1998) 3.92
Purification and amino acid sequencing of NAF, a novel neutrophil-activating factor produced by monocytes. Biochem Biophys Res Commun (1987) 3.77
Biochemical and morphological characterization of azurophil and specific granules of human neutrophilic polymorphonuclear leukocytes. J Cell Biol (1974) 3.71
HIV coreceptor downregulation as antiviral principle: SDF-1alpha-dependent internalization of the chemokine receptor CXCR4 contributes to inhibition of HIV replication. J Exp Med (1997) 3.71
B cell-attracting chemokine 1, a human CXC chemokine expressed in lymphoid tissues, selectively attracts B lymphocytes via BLR1/CXCR5. J Exp Med (1998) 3.60
Cloning of a human seven-transmembrane domain receptor, LESTR, that is highly expressed in leukocytes. J Biol Chem (1994) 3.50
Ion channels in human neutrophils activated by a rise in free cytosolic calcium concentration. Nature (1987) 3.39
Synthesis and expression in Escherichia coli of the gene encoding monocyte-derived neutrophil-activating factor: biological equivalence between natural and recombinant neutrophil-activating factor. Proc Natl Acad Sci U S A (1988) 3.37
Association of lactoferrin with specific granules in rabbit heterophil leukocytes. J Exp Med (1970) 3.32
Interleukin-2 regulates CC chemokine receptor expression and chemotactic responsiveness in T lymphocytes. J Exp Med (1996) 3.30
RANTES and macrophage inflammatory protein 1 alpha induce the migration and activation of normal human eosinophil granulocytes. J Exp Med (1992) 3.25
Extracellular labeling of nascent polypeptides traversing the membrane of Escherichia coli. Proc Natl Acad Sci U S A (1977) 3.16
Physical properties of lipid monolayers on alkylated planar glass surfaces. Biophys J (1981) 3.07
Further biochemical and morphological studies of granule fractions from rabbit heterophil leukocytes. J Cell Biol (1970) 3.06
Phagocytosing neutrophils produce and release high amounts of the neutrophil-activating peptide 1/interleukin 8. J Exp Med (1991) 2.96
Role of ribosome degradation in the death of starved Escherichia coli cells. J Bacteriol (1986) 2.86
CC chemokines in allergic inflammation. Immunol Today (1994) 2.85
Mechanism of neutrophil activation by NAF, a novel monocyte-derived peptide agonist. FASEB J (1988) 2.83
ATP is essential for protein translocation into Escherichia coli membrane vesicles. Proc Natl Acad Sci U S A (1985) 2.65
Subcellular localization and heterogeneity of neutral proteases in neutrophilic polymorphonuclear leukocytes. J Exp Med (1975) 2.64
Specific antibody-dependent interactions between macrophages and lipid haptens in planar lipid monolayers. Proc Natl Acad Sci U S A (1981) 2.55
Cold-sensitive mutations in Salmonella typhimurium which affect ribosome synthesis. J Bacteriol (1969) 2.51
HIV blocked by chemokine antagonist. Nature (1996) 2.50
Actions of the chemotactic cytokines MCP-1, MCP-2, MCP-3, RANTES, MIP-1 alpha and MIP-1 beta on human monocytes. Eur J Immunol (1995) 2.48
Structure and neutrophil-activating properties of a novel inflammatory peptide (ENA-78) with homology to interleukin 8. J Exp Med (1991) 2.46
Binding to heparan sulfate or heparin enhances neutrophil responses to interleukin 8. Proc Natl Acad Sci U S A (1993) 2.45
Neutrophil-activating protein 1/interleukin 8 stimulates the binding activity of the leukocyte adhesion receptor CD11b/CD18 on human neutrophils. J Exp Med (1990) 2.42
SecA protein is required for secretory protein translocation into E. coli membrane vesicles. Cell (1988) 2.41
In vivo inflammatory activity of neutrophil-activating factor, a novel chemotactic peptide derived from human monocytes. Am J Pathol (1989) 2.37
Subcellular localization of the superoxide-forming enzyme in human neutrophils. J Clin Invest (1979) 2.33
Secretion of lysosomal hydrolases by stimulated and nonstimulated macrophages. J Exp Med (1978) 2.32
Neutrophil activation by monomeric interleukin-8. Science (1994) 2.31
Monocyte chemotactic protein 3 is a most effective basophil- and eosinophil-activating chemokine. J Exp Med (1994) 2.29
Monocyte chemotactic proteins MCP-1, MCP-2, and MCP-3 are major attractants for human CD4+ and CD8+ T lymphocytes. FASEB J (1994) 2.27
Actions of aurintricarboxylate, kasugamycin, and pactamycin on Escherichia coli polysomes. Biochemistry (1973) 2.26
Neutrophil chemotactic factor (IL-8) gene expression by cytokine-treated retinal pigment epithelial cells. Am J Pathol (1990) 2.25
Mechanism of protein excretion by gram-negative bacteria: Pseudomonas aeruginosa exotoxin A. J Bacteriol (1983) 2.24
Studies on blood eosinophils. I. Patients with a transient eosinophilia. Clin Exp Immunol (1976) 2.22
Release of gelatinase from a novel secretory compartment of human neutrophils. J Clin Invest (1982) 2.21
Chemical synthesis, purification, and characterization of two inflammatory proteins, neutrophil activating peptide 1 (interleukin-8) and neutrophil activating peptide. Biochemistry (1991) 2.20
Neutrophil-activating properties of the melanoma growth-stimulatory activity. J Exp Med (1990) 2.17
Structure-activity relationships of chemokines. J Leukoc Biol (1995) 2.15
The chemokine SLC is expressed in T cell areas of lymph nodes and mucosal lymphoid tissues and attracts activated T cells via CCR7. Eur J Immunol (1998) 2.15
The chemokine SDF-1, stromal cell-derived factor 1, attracts early stage B cell precursors via the chemokine receptor CXCR4. Eur J Immunol (1997) 2.14
Studies on blood eosinophils. II. Patients with Löffler's cardiomyopathy. Clin Exp Immunol (1976) 2.10
Recombinant human MCP-1/JE induces chemotaxis, calcium flux, and the respiratory burst in human monocytes. Blood (1991) 2.10
Platelet factor 4 binds to interleukin 8 receptors and activates neutrophils when its N terminus is modified with Glu-Leu-Arg. Proc Natl Acad Sci U S A (1993) 2.09
High expression of the chemokine receptor CCR3 in human blood basophils. Role in activation by eotaxin, MCP-4, and other chemokines. J Clin Invest (1997) 2.09
Efficient interaction of HIV-1 with purified dendritic cells via multiple chemokine coreceptors. J Exp Med (1996) 2.08
Wortmannin binds specifically to 1-phosphatidylinositol 3-kinase while inhibiting guanine nucleotide-binding protein-coupled receptor signaling in neutrophil leukocytes. Proc Natl Acad Sci U S A (1994) 2.07
Monocyte chemotactic protein 1 is a potent activator of human basophils. J Exp Med (1992) 2.07
Enhanced production of neutrophil-activating peptide-1/interleukin-8 in rheumatoid arthritis. J Clin Invest (1991) 2.04
Activation of NK cells by CC chemokines. Chemotaxis, Ca2+ mobilization, and enzyme release. J Immunol (1996) 1.99
Effects of the neutrophil-activating peptide NAP-2, platelet basic protein, connective tissue-activating peptide III and platelet factor 4 on human neutrophils. J Exp Med (1989) 1.98
Human alveolar macrophage gene expression of interleukin-8 by tumor necrosis factor-alpha, lipopolysaccharide, and interleukin-1 beta. Am J Respir Cell Mol Biol (1990) 1.98
Deposits of eosinophil granule proteins in cardiac tissues of patients with eosinophilic endomyocardial disease. Lancet (1987) 1.98
Properties of initiation-free polysomes of Escherichia coli. Biochemistry (1973) 1.97
Enhanced production of monocyte chemotactic protein 3 in inflammatory bowel disease mucosa. Gut (1999) 1.97
An alternative view of phospholipid phase behavior at the air-water interface. Microscope and film balance studies. Biophys J (1981) 1.97
Clinical features of fifteen patients with the hypereosinophilic syndrome. Q J Med (1983) 1.96
BCA-1 is highly expressed in Helicobacter pylori-induced mucosa-associated lymphoid tissue and gastric lymphoma. J Clin Invest (1999) 1.94
Misread protein creates membrane channels: an essential step in the bactericidal action of aminoglycosides. Proc Natl Acad Sci U S A (1986) 1.94
The interleukin-8-related chemotactic cytokines GRO alpha, GRO beta, and GRO gamma activate human neutrophil and basophil leukocytes. J Biol Chem (1993) 1.92
Bifurcation of lipid and protein kinase signals of PI3Kgamma to the protein kinases PKB and MAPK. Science (1998) 1.89
The ligands of CXC chemokine receptor 3, I-TAC, Mig, and IP10, are natural antagonists for CCR3. J Biol Chem (2000) 1.86
Assay of H2O2 production by macrophages and neutrophils with homovanillic acid and horse-radish peroxidase. J Immunol Methods (1983) 1.85
Cell cycle-dependent expression of CXC chemokine receptor 3 by endothelial cells mediates angiostatic activity. J Clin Invest (2001) 1.84
Neutrophil-activating peptide 2 and gro/melanoma growth-stimulatory activity interact with neutrophil-activating peptide 1/interleukin 8 receptors on human neutrophils. J Biol Chem (1991) 1.83
Quantitative analysis of the cytosolic free calcium dependency of exocytosis from three subcellular compartments in intact human neutrophils. J Cell Biol (1986) 1.82
Alkaline phosphatase and OmpA protein can be translocated posttranslationally into membrane vesicles of Escherichia coli. J Bacteriol (1985) 1.82
Role of phagocytosis in the activation of macrophages. J Exp Med (1978) 1.77
Turning on the respiratory burst. Trends Biochem Sci (1990) 1.75
Leptin promotes invasiveness of kidney and colonic epithelial cells via phosphoinositide 3-kinase-, rho-, and rac-dependent signaling pathways. FASEB J (2000) 1.75
Monoclonal antibodies distinguish between storage and secreted forms of eosinophil cationic protein. Nature (1984) 1.75
Cytochemical localization of acid phosphatase activity in granule fractions from rabbit polymorphonuclear leukocytes. J Cell Biol (1972) 1.74
Energy-requiring translocation of the OmpA protein and alkaline phosphatase of Escherichia coli into inner membrane vesicles. J Bacteriol (1984) 1.74
Biochemical evidence for the secY24 defect in Escherichia coli protein translocation and its suppression by soluble cytoplasmic factors. Proc Natl Acad Sci U S A (1987) 1.74
Large mononuclear (veiled) cells like 'Ia-like' membrane antigens in human afferent lympn. Clin Exp Immunol (1980) 1.74