Published in Cancer Res on April 20, 2010
Involvement of DNA-dependent protein kinase in normal cell cycle progression through mitosis. J Biol Chem (2011) 1.13
Role of DNA-dependent protein kinase catalytic subunit in cancer development and treatment. Transl Cancer Res (2012) 1.08
CHK2 kinase in the DNA damage response and beyond. J Mol Cell Biol (2014) 1.05
Targeting MPS1 Enhances Radiosensitization of Human Glioblastoma by Modulating DNA Repair Proteins. Mol Cancer Res (2015) 1.01
A double-edged sword: how oncogenes and tumor suppressor genes can contribute to chromosomal instability. Front Oncol (2013) 1.00
4E-BP1 participates in maintaining spindle integrity and genomic stability via interacting with PLK1. Cell Cycle (2012) 0.98
The DNA-dependent protein kinase: A multifunctional protein kinase with roles in DNA double strand break repair and mitosis. Prog Biophys Mol Biol (2014) 0.96
The NF90/NF45 complex participates in DNA break repair via nonhomologous end joining. Mol Cell Biol (2011) 0.93
Polo-like kinase 1 (PLK1) and protein phosphatase 6 (PP6) regulate DNA-dependent protein kinase catalytic subunit (DNA-PKcs) phosphorylation in mitosis. Biosci Rep (2014) 0.90
DNA-PKcs activates the Chk2-Brca1 pathway during mitosis to ensure chromosomal stability. Oncogenesis (2014) 0.90
Phosphorylation of SMC1 by ATR is required for desferrioxamine (DFO)-induced apoptosis. Cell Death Dis (2011) 0.89
The influence of AKT isoforms on radiation sensitivity and DNA repair in colon cancer cell lines. Tumour Biol (2013) 0.89
Steroidogenic Factor 1 (NR5A1) resides in centrosomes and maintains genomic stability by controlling centrosome homeostasis. Cell Death Differ (2011) 0.88
PIG3 functions in DNA damage response through regulating DNA-PKcs homeostasis. Int J Biol Sci (2013) 0.87
NSCLC cells demonstrate differential mode of cell death in response to the combined treatment of radiation and a DNA-PKcs inhibitor. Oncotarget (2015) 0.85
RNF144A, an E3 ubiquitin ligase for DNA-PKcs, promotes apoptosis during DNA damage. Proc Natl Acad Sci U S A (2014) 0.83
Steroidogenic factor 1 (NR5A1) maintains centrosome homeostasis in steroidogenic cells by restricting centrosomal DNA-dependent protein kinase activation. Mol Cell Biol (2012) 0.82
DNA-PK triggers histone ubiquitination and signaling in response to DNA double-strand breaks produced during the repair of transcription-blocking topoisomerase I lesions. Nucleic Acids Res (2015) 0.80
In vitro and in vivo radiosensitization induced by hydroxyapatite nanoparticles. Neuro Oncol (2013) 0.79
WISP-1 contributes to fractionated irradiation-induced radioresistance in esophageal carcinoma cell lines and mice. PLoS One (2014) 0.79
The novel HSP90 inhibitor AT13387 potentiates radiation effects in squamous cell carcinoma and adenocarcinoma cells. Oncotarget (2015) 0.78
Genotypic characteristics of resistant tumors to pre-operative ionizing radiation in rectal cancer. World J Gastrointest Oncol (2014) 0.77
TNKS1BP1 functions in DNA double-strand break repair though facilitating DNA-PKcs autophosphorylation dependent on PARP-1. Oncotarget (2015) 0.77
Deregulation of DNA-dependent protein kinase catalytic subunit contributes to human hepatocarcinogenesis development and has a putative prognostic value. Br J Cancer (2013) 0.77
DNA damage to a single chromosome end delays anaphase onset. J Biol Chem (2014) 0.77
Phosphorylation of SAF-A/hnRNP-U Serine 59 by Polo-Like Kinase 1 Is Required for Mitosis. Mol Cell Biol (2015) 0.76
DNA double-strand break repair is impaired in presenescent Syrian hamster fibroblasts. BMC Mol Biol (2015) 0.75
PIG3 promotes NSCLC cell mitotic progression and is associated with poor prognosis of NSCLC patients. J Exp Clin Cancer Res (2017) 0.75
Suppression of PC-1/PrLZ sensitizes prostate cancer cells to ionizing radiation by attenuating DNA damage repair and inducing autophagic cell death. Oncotarget (2016) 0.75
Inhibiting DNA-PKcs in a non-homologous end-joining pathway in response to DNA double-strand breaks. Oncotarget (2017) 0.75
Ectopic TLX1 expression accelerates malignancies in mice deficient in DNA-PK. PLoS One (2014) 0.75
DNA-PKcs Negatively Regulates Cyclin B1 Protein Stability through Facilitating Its Ubiquitination Mediated by Cdh1-APC/C Pathway. Int J Biol Sci (2015) 0.75
Synergy between Prkdc and Trp53 regulates stem cell proliferation and GI-ARS after irradiation. Cell Death Differ (2017) 0.75
Inhibition of c-Myc expression accounts for an increase in the number of multinucleated cells in human cervical epithelial cells. Oncol Lett (2017) 0.75
Human infection with a novel avian-origin influenza A (H7N9) virus. N Engl J Med (2013) 24.88
The Sorghum bicolor genome and the diversification of grasses. Nature (2009) 14.62
Fever with thrombocytopenia associated with a novel bunyavirus in China. N Engl J Med (2011) 13.18
Complete MHC haplotype sequencing for common disease gene mapping. Genome Res (2004) 12.09
Multicolor super-resolution imaging with photo-switchable fluorescent probes. Science (2007) 9.00
A recurrent 15q13.3 microdeletion syndrome associated with mental retardation and seizures. Nat Genet (2008) 8.44
Rapid health transition in China, 1990-2010: findings from the Global Burden of Disease Study 2010. Lancet (2013) 7.70
Epidemiology of human infections with avian influenza A(H7N9) virus in China. N Engl J Med (2013) 7.52
Evolution of China's response to HIV/AIDS. Lancet (2007) 7.34
A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development. J Exp Med (2006) 6.86
Epidemiological serosurvey of hepatitis B in China--declining HBV prevalence due to hepatitis B vaccination. Vaccine (2009) 6.30
National survey of drug-resistant tuberculosis in China. N Engl J Med (2012) 6.28
Origin and diversity of novel avian influenza A H7N9 viruses causing human infection: phylogenetic, structural, and coalescent analyses. Lancet (2013) 6.10
A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein. Proc Natl Acad Sci U S A (2007) 6.04
Emergence and control of infectious diseases in China. Lancet (2008) 5.93
Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters. Nat Genet (2011) 5.62
Phase III randomized clinical trial comparing tremelimumab with standard-of-care chemotherapy in patients with advanced melanoma. J Clin Oncol (2013) 5.36
The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice. J Clin Invest (2003) 5.32
Nosocomial transmission of human granulocytic anaplasmosis in China. JAMA (2008) 5.01
Genome sequence of Shigella flexneri 2a: insights into pathogenicity through comparison with genomes of Escherichia coli K12 and O157. Nucleic Acids Res (2002) 4.92
Coordinated regulation of Arabidopsis thaliana development by light and gibberellins. Nature (2008) 4.71
Safety and immunogenicity of an inactivated adjuvanted whole-virion influenza A (H5N1) vaccine: a phase I randomised controlled trial. Lancet (2006) 4.22
Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP. Genes Dev (2012) 4.19
Probable limited person-to-person transmission of highly pathogenic avian influenza A (H5N1) virus in China. Lancet (2008) 4.17
Safety and immunogenicity of 2009 pandemic influenza A H1N1 vaccines in China: a multicentre, double-blind, randomised, placebo-controlled trial. Lancet (2009) 3.97
Human infection with avian influenza A H7N9 virus: an assessment of clinical severity. Lancet (2013) 3.90
An emerging recombinant human enterovirus 71 responsible for the 2008 outbreak of hand foot and mouth disease in Fuyang city of China. Virol J (2010) 3.90
Rapid growth of a hepatocellular carcinoma and the driving mutations revealed by cell-population genetic analysis of whole-genome data. Proc Natl Acad Sci U S A (2011) 3.80
Comparative epidemiology of human infections with avian influenza A H7N9 and H5N1 viruses in China: a population-based study of laboratory-confirmed cases. Lancet (2013) 3.77
Person-to-person transmission of severe fever with thrombocytopenia syndrome virus. Vector Borne Zoonotic Dis (2011) 3.73
Human Streptococcus suis outbreak, Sichuan, China. Emerg Infect Dis (2006) 3.65
Genome dynamics and diversity of Shigella species, the etiologic agents of bacillary dysentery. Nucleic Acids Res (2005) 3.56
Superresolution imaging of chemical synapses in the brain. Neuron (2010) 3.51
The role of CXCR7/RDC1 as a chemokine receptor for CXCL12/SDF-1 in prostate cancer. J Biol Chem (2007) 3.38
Conformational biosensors reveal GPCR signalling from endosomes. Nature (2013) 3.29
Biological features of novel avian influenza A (H7N9) virus. Nature (2013) 3.24
Temporal relationship and predictive value of urinary acute kidney injury biomarkers after pediatric cardiopulmonary bypass. J Am Coll Cardiol (2011) 3.17
Effectiveness of strengthened stimulation during acupuncture for the treatment of Bell palsy: a randomized controlled trial. CMAJ (2013) 3.15
Streptococcal toxic shock syndrome caused by Streptococcus suis serotype 2. PLoS Med (2006) 2.99
Ca2+-dependent activation of Rho and Rho kinase in membrane depolarization-induced and receptor stimulation-induced vascular smooth muscle contraction. Circ Res (2003) 2.85
Synthesis of N-doped graphene by chemical vapor deposition and its electrical properties. Nano Lett (2009) 2.85
Cerebrospinal fluid biomarkers for Parkinson disease diagnosis and progression. Ann Neurol (2011) 2.84
Retracted An endogenous, systemic RNAi pathway in plants. EMBO J (2010) 2.82
The Chinese free antiretroviral treatment program: challenges and responses. AIDS (2007) 2.73
Adipocyte fatty acid-binding protein is a plasma biomarker closely associated with obesity and metabolic syndrome. Clin Chem (2006) 2.63
Angiopoietin-like protein 4 decreases blood glucose and improves glucose tolerance but induces hyperlipidemia and hepatic steatosis in mice. Proc Natl Acad Sci U S A (2005) 2.63
Evaluation of the impact of hepatitis B vaccination among children born during 1992-2005 in China. J Infect Dis (2009) 2.62
Faster STORM using compressed sensing. Nat Methods (2012) 2.61
Identification and control of a poliomyelitis outbreak in Xinjiang, China. N Engl J Med (2013) 2.55
A clinical microchip for evaluation of single immune cells reveals high functional heterogeneity in phenotypically similar T cells. Nat Med (2011) 2.54
Adiponectin mediates the metabolic effects of FGF21 on glucose homeostasis and insulin sensitivity in mice. Cell Metab (2013) 2.49
Colloids with valence and specific directional bonding. Nature (2012) 2.49
Super-resolution fluorescence imaging of organelles in live cells with photoswitchable membrane probes. Proc Natl Acad Sci U S A (2012) 2.46
The Kluyveromyces lactis gamma-toxin targets tRNA anticodons. RNA (2005) 2.39
DCDC2 is associated with reading disability and modulates neuronal development in the brain. Proc Natl Acad Sci U S A (2005) 2.35
Structures and receptor binding of hemagglutinins from human-infecting H7N9 influenza viruses. Science (2013) 2.34
ProfCom: a web tool for profiling the complex functionality of gene groups identified from high-throughput data. Nucleic Acids Res (2008) 2.33
Circulating adipocyte-fatty acid binding protein levels predict the development of the metabolic syndrome: a 5-year prospective study. Circulation (2007) 2.29
Clinical characteristics of 26 human cases of highly pathogenic avian influenza A (H5N1) virus infection in China. PLoS One (2008) 2.28
Testosterone selectively reduces the high molecular weight form of adiponectin by inhibiting its secretion from adipocytes. J Biol Chem (2005) 2.28
Switch of glycolysis to gluconeogenesis by dexamethasone for treatment of hepatocarcinoma. Nat Commun (2013) 2.27
HIV and syphilis prevalence among men who have sex with men: a cross-sectional survey of 61 cities in China. Clin Infect Dis (2013) 2.24
Elevated levels of two tRNA species bypass the requirement for elongator complex in transcription and exocytosis. Mol Cell (2006) 2.22
Eukaryotic wobble uridine modifications promote a functionally redundant decoding system. Mol Cell Biol (2008) 2.21
Electrostatic control of ions and molecules in nanofluidic transistors. Nano Lett (2005) 2.21
SIRT1 promotes proliferation and prevents senescence through targeting LKB1 in primary porcine aortic endothelial cells. Circ Res (2010) 2.20
Elucidation of CXCR7-mediated signaling events and inhibition of CXCR4-mediated tumor cell transendothelial migration by CXCR7 ligands. J Immunol (2009) 2.19
CCR1 blockade reduces tumor burden and osteolysis in vivo in a mouse model of myeloma bone disease. Blood (2012) 2.18
IL-17-producing alveolar macrophages mediate allergic lung inflammation related to asthma. J Immunol (2008) 2.17
Replacement of Oct4 by Tet1 during iPSC induction reveals an important role of DNA methylation and hydroxymethylation in reprogramming. Cell Stem Cell (2013) 2.17
Soft fibrin gels promote selection and growth of tumorigenic cells. Nat Mater (2012) 2.15
The chromosome 6p22 haplotype associated with dyslexia reduces the expression of KIAA0319, a novel gene involved in neuronal migration. Hum Mol Genet (2006) 2.14
No significant association between the TP53 codon 72 polymorphism and breast cancer risk: a meta-analysis of 21 studies involving 24,063 subjects. Breast Cancer Res Treat (2010) 2.12
Concern Misregulation of AUXIN RESPONSE FACTOR 8 underlies the developmental abnormalities caused by three distinct viral silencing suppressors in Arabidopsis. PLoS Pathog (2011) 2.12
Cyclooxygenase-2 inhibition by celecoxib reduces proliferation and induces apoptosis in angiogenic endothelial cells in vivo. Cancer Res (2002) 2.09
Retracted Randomized clinical trial of arginine-supplemented enteral nutrition versus standard enteral nutrition in patients undergoing gastric cancer surgery. J Cancer Res Clin Oncol (2013) 2.08
Adiponectin-induced endothelial nitric oxide synthase activation and nitric oxide production are mediated by APPL1 in endothelial cells. Diabetes (2007) 2.08
Streptococcus suis sequence type 7 outbreak, Sichuan, China. Emerg Infect Dis (2006) 2.07
Negative regulation of NF-kappaB action by Set9-mediated lysine methylation of the RelA subunit. EMBO J (2009) 2.05
Myelopathy due to calcified meningiomas of the thoracic spine: minimum 3-year follow-up after surgical treatment. J Neurosurg Spine (2013) 2.02
Controlled growth of Si nanowire arrays for device integration. Nano Lett (2005) 2.02
Identification of a functional genetic variant at 16q12.1 for breast cancer risk: results from the Asia Breast Cancer Consortium. PLoS Genet (2010) 1.98
Estimating the number of people living with HIV/AIDS in China: 2003-09. Int J Epidemiol (2010) 1.96
Serum adipocyte fatty acid binding protein as a new biomarker predicting the development of type 2 diabetes: a 10-year prospective study in a Chinese cohort. Diabetes Care (2007) 1.88
A conserved modified wobble nucleoside (mcm5s2U) in lysyl-tRNA is required for viability in yeast. RNA (2007) 1.88
Risk factors for severe illness with 2009 pandemic influenza A (H1N1) virus infection in China. Clin Infect Dis (2011) 1.87
Indications that live poultry markets are a major source of human H5N1 influenza virus infection in China. J Virol (2011) 1.85
GSK3-TIP60-ULK1 signaling pathway links growth factor deprivation to autophagy. Science (2012) 1.84
Local accumulation of FOXP3+ regulatory T cells: evidence for an immune evasion mechanism in patients with large condylomata acuminata. J Immunol (2008) 1.83
Oxytocin deficiency mediates hyperphagic obesity of Sim1 haploinsufficient mice. Mol Endocrinol (2008) 1.83
Fibroblast growth factor 21 protects against acetaminophen-induced hepatotoxicity by potentiating peroxisome proliferator-activated receptor coactivator protein-1α-mediated antioxidant capacity in mice. Hepatology (2014) 1.80
Diverse set of microRNAs are responsive to powdery mildew infection and heat stress in wheat (Triticum aestivum L.). BMC Plant Biol (2010) 1.80
1B50-1, a mAb raised against recurrent tumor cells, targets liver tumor-initiating cells by binding to the calcium channel α2δ1 subunit. Cancer Cell (2013) 1.79
The first confirmed human case of avian influenza A (H5N1) in Mainland China. Lancet (2006) 1.79
Organization of the Caenorhabditis elegans small non-coding transcriptome: genomic features, biogenesis, and expression. Genome Res (2005) 1.77
Single-cell proteomic chip for profiling intracellular signaling pathways in single tumor cells. Proc Natl Acad Sci U S A (2011) 1.76
Generation of human induced pluripotent stem cells from urine samples. Nat Protoc (2012) 1.76
Structure of the APPL1 BAR-PH domain and characterization of its interaction with Rab5. EMBO J (2007) 1.74
Regulation of cyclin dependent kinase 6 by microRNA 124 in medulloblastoma. J Neurooncol (2008) 1.72