Published in Front Mol Neurosci on March 29, 2010
The GABAergic deficit hypothesis of major depressive disorder. Mol Psychiatry (2010) 1.80
Toward a biosignature for suicide. Am J Psychiatry (2014) 1.03
Why are cortical GABA neurons relevant to internal focus in depression? A cross-level model linking cellular, biochemical and neural network findings. Mol Psychiatry (2014) 0.84
Altered expression of neuroplasticity-related genes in the brain of depressed suicides. Neuroscience (2015) 0.83
An overview of the neurobiology of suicidal behaviors as one meta-system. Mol Psychiatry (2014) 0.77
Suicide attempters with Borderline Personality Disorder show differential orbitofrontal and parietal recruitment when reflecting on aversive memories. J Psychiatr Res (2016) 0.75
Inhibition of glutamine synthetase in the central nucleus of the amygdala induces anhedonic behavior and recurrent seizures in a rat model of mesial temporal lobe epilepsy. Epilepsy Behav (2015) 0.75
The Life Span Model of Suicide and Its Neurobiological Foundation. Front Neurosci (2017) 0.75
Hippocampal bone morphogenetic protein signaling mediates behavioral effects of antidepressant treatment. Mol Psychiatry (2016) 0.75
Frontiers in molecular neuroscience - résumé and perspective. Front Mol Neurosci (2011) 0.75
Expression of p21-activated kinases 1 and 3 is altered in the brain of subjects with depression. Neuroscience (2016) 0.75
Neuropathology of suicide: recent findings and future directions. Mol Psychiatry (2017) 0.75
Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. Science (2003) 28.61
A neurotrophic model for stress-related mood disorders. Biol Psychiatry (2006) 8.97
RNA integrity and the effect on the real-time qRT-PCR performance. Mol Aspects Med (2006) 7.37
Gamma oscillation by synaptic inhibition in a hippocampal interneuronal network model. J Neurosci (1996) 6.33
Similar network activity from disparate circuit parameters. Nat Neurosci (2004) 5.94
Selective changes in single cell GABA(A) receptor subunit expression and function in temporal lobe epilepsy. Nat Med (1998) 4.16
The interaction of stressful life events and a serotonin transporter polymorphism in the prediction of episodes of major depression: a replication. Arch Gen Psychiatry (2005) 3.96
Neuroimaging studies of mood disorders. Biol Psychiatry (2000) 3.92
Comparison of relative mRNA quantification models and the impact of RNA integrity in quantitative real-time RT-PCR. Biotechnol Lett (2006) 3.53
Analysis of gamma rhythms in the rat hippocampus in vitro and in vivo. J Physiol (1996) 3.36
Altered gene expression of brain-derived neurotrophic factor and receptor tyrosine kinase B in postmortem brain of suicide subjects. Arch Gen Psychiatry (2003) 2.82
Protein pathway and complex clustering of correlated mRNA and protein expression analyses in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (2003) 2.73
Altered cortical glutamatergic and GABAergic signal transmission with glial involvement in depression. Proc Natl Acad Sci U S A (2005) 2.38
GABAA receptor promoter hypermethylation in suicide brain: implications for the involvement of epigenetic processes. Biol Psychiatry (2008) 2.04
GABAA receptor subunit gamma2 and delta subtypes confer unique kinetic properties on recombinant GABAA receptor currents in mouse fibroblasts. J Physiol (1999) 2.02
Corticotropin-releasing factor receptors 1 and 2 in anxiety and depression. Curr Opin Pharmacol (2002) 1.97
The corticotropin-releasing factor (CRF) hypothesis of depression: new findings and new directions. Mol Psychiatry (1996) 1.95
Formation and plasticity of GABAergic synapses: physiological mechanisms and pathophysiological implications. Pharmacol Ther (2003) 1.83
Autoregulation of serotonin neurons: role in antidepressant drug action. Pharmacol Rev (1999) 1.69
Differential role of the orbital frontal lobe in emotional versus cognitive perspective-taking. Neuropsychologia (2005) 1.65
Dysregulation in the suicide brain: mRNA expression of corticotropin-releasing hormone receptors and GABA(A) receptor subunits in frontal cortical brain region. J Neurosci (2004) 1.62
Multi-target strategies for the improved treatment of depressive states: Conceptual foundations and neuronal substrates, drug discovery and therapeutic application. Pharmacol Ther (2006) 1.59
Reelin and glutamic acid decarboxylase67 promoter remodeling in an epigenetic methionine-induced mouse model of schizophrenia. Proc Natl Acad Sci U S A (2005) 1.56
Synaptic communication among hippocampal interneurons: properties of spontaneous IPSCs in morphologically identified cells. J Neurosci (1997) 1.51
Evidence for a dysfunctional prefrontal circuit in patients with an impulsive aggressive disorder. Proc Natl Acad Sci U S A (2002) 1.51
Patterns of gene expression in the limbic system of suicides with and without major depression. Mol Psychiatry (2007) 1.47
Genome wide gene expression studies in mood disorders. OMICS (2006) 1.35
Brain-derived neurotrophic factor (BDNF)-induced synthesis of early growth response factor 3 (Egr3) controls the levels of type A GABA receptor alpha 4 subunits in hippocampal neurons. J Biol Chem (2006) 1.33
The human reelin gene: transcription factors (+), repressors (-) and the methylation switch (+/-) in schizophrenia. Pharmacol Ther (2006) 1.32
GABAergic contributions to the pathophysiology of depression and the mechanism of antidepressant action. CNS Neurol Disord Drug Targets (2007) 1.24
Human neuronal gamma-aminobutyric acid(A) receptors: coordinated subunit mRNA expression and functional correlates in individual dentate granule cells. J Neurosci (1999) 1.24
GABAA receptors: building the bridge between subunit mRNAs, their promoters, and cognate transcription factors. Pharmacol Ther (2004) 1.20
A GABRB3 promoter haplotype associated with childhood absence epilepsy impairs transcriptional activity. Hum Mol Genet (2006) 1.16
Neurotrophic signaling cascades in the pathophysiology and treatment of bipolar disorder. Curr Opin Pharmacol (2006) 1.16
Suicide, serotonin, and the brain. Crisis (2001) 1.16
Slow oscillations (</=1 Hz) mediated by GABAergic interneuronal networks in rat hippocampus. J Neurosci (1998) 1.09
alpha-[11C]Methyl-L-tryptophan trapping in the orbital and ventral medial prefrontal cortex of suicide attempters. Eur Neuropsychopharmacol (2005) 1.03
Organization of GABA receptor alpha-subunit clustering in the developing rat neocortex and hippocampus. Eur J Neurosci (2004) 1.02
Reciprocal inhibitory connections regulate the spatiotemporal properties of intrathalamic oscillations. J Neurosci (2000) 1.01
Bombesin receptors as a novel anti-anxiety therapeutic target: BB1 receptor actions on anxiety through alterations of serotonin activity. J Neurosci (2006) 1.00
Transcriptional regulation of the mouse gene encoding the alpha-4 subunit of the GABAA receptor. J Biol Chem (2004) 0.99
Activity-induced expression of common reference genes in individual cns neurons. Lab Invest (2001) 0.96
An initiator element mediates autologous downregulation of the human type A gamma -aminobutyric acid receptor beta 1 subunit gene. Proc Natl Acad Sci U S A (2000) 0.93
Corticotropin releasing hormone receptor alterations elicited by acute and chronic unpredictable stressor challenges in stressor-susceptible and resilient strains of mice. Behav Brain Res (2007) 0.92
Central GABAergic systems and depressive illness. Neurochem Res (2003) 0.89
GABAA receptors as targets for novel anxiolytic drugs. World J Biol Psychiatry (2006) 0.87
Human gamma-aminobutyric acid-type A receptor alpha5 subunit gene (GABRA5): characterization and structural organization of the 5' flanking region. Genomics (1997) 0.87
The mouse GABA(A) receptor alpha3 subunit gene and promoter. Brain Res Mol Brain Res (1999) 0.83
Multiple GABAA receptor subtypes regulate hippocampal ripple oscillations. Eur J Neurosci (2004) 0.83
A minimal promoter for the GABA(A) receptor alpha6-subunit gene controls tissue specificity. J Neurochem (2000) 0.81
Isolation and characterization of the promoter of the human GABAA receptor alpha 1 subunit gene. J Neurochem (1994) 0.81
The 5'-flanking region of the rat GABA(A) receptor alpha2-subunit gene (Gabra2). J Neurochem (2002) 0.78
Activation of the GABA(A)-receptor delta-subunit gene promoter following pentylenetetrazole-induced seizures in transgenic mice. Brain Res Mol Brain Res (1997) 0.77
Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine (MPTP) and oxidative stress. Proc Natl Acad Sci U S A (2005) 3.83
The genome of Tetranychus urticae reveals herbivorous pest adaptations. Nature (2011) 3.29
Impaired repression at a 5-hydroxytryptamine 1A receptor gene polymorphism associated with major depression and suicide. J Neurosci (2003) 2.67
Impact of stressors in a natural context on release of cortisol in healthy adult humans: a meta-analysis. Stress (2008) 2.15
GABAA receptor promoter hypermethylation in suicide brain: implications for the involvement of epigenetic processes. Biol Psychiatry (2008) 2.04
Cyclin-dependent kinase 5 is a mediator of dopaminergic neuron loss in a mouse model of Parkinson's disease. Proc Natl Acad Sci U S A (2003) 1.87
The LIM-homeobox gene Lhx8 is required for the development of many cholinergic neurons in the mouse forebrain. Proc Natl Acad Sci U S A (2003) 1.85
Inhibition of calpains prevents neuronal and behavioral deficits in an MPTP mouse model of Parkinson's disease. J Neurosci (2003) 1.74
Dysregulation in the suicide brain: mRNA expression of corticotropin-releasing hormone receptors and GABA(A) receptor subunits in frontal cortical brain region. J Neurosci (2004) 1.62
Neurotransmitter, peptide and cytokine processes in relation to depressive disorder: comorbidity between depression and neurodegenerative disorders. Prog Neurobiol (2008) 1.61
Calpain-regulated p35/cdk5 plays a central role in dopaminergic neuron death through modulation of the transcription factor myocyte enhancer factor 2. J Neurosci (2006) 1.61
A peculiar constellation of tau pathology defines a subset of dementia in the elderly. Acta Neuropathol (2011) 1.60
Involvement of interferon-gamma in microglial-mediated loss of dopaminergic neurons. J Neurosci (2007) 1.55
Maternal programming of defensive responses through sustained effects on gene expression. Biol Psychol (2006) 1.55
Association of the C(-1019)G 5-HT1A functional promoter polymorphism with antidepressant response. Int J Neuropsychopharmacol (2004) 1.53
Tuberoinfundibular peptide of 39 residues is activated during lactation and participates in the suckling-induced prolactin release in rat. Endocrinology (2010) 1.51
Cytokines, stress and depressive illness: brain-immune interactions. Ann Med (2003) 1.44
CRF receptor 1 regulates anxiety behavior via sensitization of 5-HT2 receptor signaling. Nat Neurosci (2010) 1.38
Evaluation of the effects of chronic mild stressors on hedonic and physiological responses: sex and strain compared. Brain Res (2003) 1.37
Therapeutic and protective effect of environmental enrichment against psychogenic and neurogenic stress. Behav Brain Res (2006) 1.35
Downregulation of the CB1 cannabinoid receptor and related molecular elements of the endocannabinoid system in epileptic human hippocampus. J Neurosci (2008) 1.32
Religiosity as identity: toward an understanding of religion from a social identity perspective. Pers Soc Psychol Rev (2010) 1.31
Dissociating anorexia and anhedonia elicited by interleukin-1beta: antidepressant and gender effects on responding for "free chow" and "earned" sucrose intake. Psychopharmacology (Berl) (2002) 1.30
Cytokines as a precipitant of depressive illness: animal and human studies. Curr Pharm Des (2005) 1.30
Serotonin receptor subtype and p11 mRNA expression in stress-relevant brain regions of suicide and control subjects. J Psychiatry Neurosci (2008) 1.30
Cocaine- and amphetamine-related transcript is involved in the orexigenic effect of endogenous anandamide. Neuroendocrinology (2005) 1.26
Novel tracing paradigms--genetically engineered herpesviruses as tools for mapping functional circuits within the CNS: present status and future prospects. Prog Neurobiol (2004) 1.25
Validation of a simple, ethologically relevant paradigm for assessing anxiety in mice. Biol Psychiatry (2003) 1.24
The Edinger-Westphal nucleus: a historical, structural, and functional perspective on a dichotomous terminology. J Comp Neurol (2011) 1.24
Functional interactions between dopamine, serotonin and norepinephrine neurons: an in-vivo electrophysiological study in rats with monoaminergic lesions. Int J Neuropsychopharmacol (2008) 1.23
miR-7b, a microRNA up-regulated in the hypothalamus after chronic hyperosmolar stimulation, inhibits Fos translation. Proc Natl Acad Sci U S A (2006) 1.22
Maternal behavior regulates benzodiazepine/GABAA receptor subunit expression in brain regions associated with fear in BALB/c and C57BL/6 mice. Neuropsychopharmacology (2004) 1.22
Uncoupling the dopamine D1-D2 receptor complex exerts antidepressant-like effects. Nat Med (2010) 1.22
Expression and distribution of tuberoinfundibular peptide of 39 residues in the rat central nervous system. J Comp Neurol (2003) 1.22
A critical role for the cannabinoid CB1 receptors in alcohol dependence and stress-stimulated ethanol drinking. J Neurosci (2003) 1.17
Anatomical and physiological evidence for involvement of tuberoinfundibular peptide of 39 residues in nociception. Proc Natl Acad Sci U S A (2002) 1.14
A paradoxical association of an oxytocin receptor gene polymorphism: early-life adversity and vulnerability to depression. Front Neurosci (2013) 1.14
Regulation of dopaminergic loss by Fas in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease. J Neurosci (2004) 1.13
Synergistic and additive actions of a psychosocial stressor and endotoxin challenge: Circulating and brain cytokines, plasma corticosterone and behavioral changes in mice. Brain Behav Immun (2008) 1.12
RASGRF2 regulates alcohol-induced reinforcement by influencing mesolimbic dopamine neuron activity and dopamine release. Proc Natl Acad Sci U S A (2012) 1.06
Human NPY promoter variation rs16147:T>C as a moderator of prefrontal NPY gene expression and negative affect. Hum Mutat (2010) 1.06
Cytokines as a stressor: implications for depressive illness. Int J Neuropsychopharmacol (2002) 1.04
Calcitonin gene-related peptide-containing pathways in the rat forebrain. J Comp Neurol (2005) 1.03
Bombesin-like peptides and associated receptors within the brain: distribution and behavioral implications. Peptides (2004) 1.02
Glutamate uptake triggers transporter-mediated GABA release from astrocytes. PLoS One (2009) 1.01
Effects of stressors and immune activating agents on peripheral and central cytokines in mouse strains that differ in stressor responsivity. Brain Behav Immun (2010) 1.01
Systems of coping associated with dysphoria, anxiety and depressive illness: a multivariate profile perspective. Stress (2003) 1.00
The impact of stressors on second generation Indian Residential School survivors. Transcult Psychiatry (2011) 1.00
Increased serotonin-1A (5-HT1A) autoreceptor expression and reduced raphe serotonin levels in deformed epidermal autoregulatory factor-1 (Deaf-1) gene knock-out mice. J Biol Chem (2012) 1.00
Bombesin receptors as a novel anti-anxiety therapeutic target: BB1 receptor actions on anxiety through alterations of serotonin activity. J Neurosci (2006) 1.00
The TIP39-PTH2 receptor system: unique peptidergic cell groups in the brainstem and their interactions with central regulatory mechanisms. Prog Neurobiol (2009) 0.99
Unconventional translation initiation of human trypsinogen 4 at a CUG codon with an N-terminal leucine. A possible means to regulate gene expression. FEBS J (2007) 0.99
Astrocytes convert network excitation to tonic inhibition of neurons. BMC Biol (2012) 0.99
Moonlighting proteins and protein-protein interactions as neurotherapeutic targets in the G protein-coupled receptor field. Neuropsychopharmacology (2013) 0.98
Influence of poly I:C on sickness behaviors, plasma cytokines, corticosterone and central monoamine activity: moderation by social stressors. Brain Behav Immun (2007) 0.98
Stress, coping, uplifts, and quality of life in subtypes of depression: a conceptual frame and emerging data. J Affect Disord (2002) 0.97
Anticipatory cues differentially provoke in vivo peptidergic and monoaminergic release at the medial prefrontal cortex. Neuropsychopharmacology (2004) 0.96
Emerging functions for tuberoinfundibular peptide of 39 residues. Trends Endocrinol Metab (2003) 0.96
Further evidence for the depressive effects of cytokines: anhedonia and neurochemical changes. Brain Behav Immun (2002) 0.96
Experiential and genetic contributions to depressive- and anxiety-like disorders: clinical and experimental studies. Neurosci Biobehav Rev (2008) 0.95
Corticotropin-releasing hormone, arginine vasopressin, gastrin-releasing peptide, and neuromedin B alterations in stress-relevant brain regions of suicides and control subjects. Biol Psychiatry (2005) 0.95
G protein-coupled receptor heterodimerization in the brain. Methods Enzymol (2013) 0.94
Animation-based education as a gambling prevention tool: correcting erroneous cognitions and reducing the frequency of exceeding limits among slots players. J Gambl Stud (2010) 0.94
Sensitization associated with stressors and cytokine treatments. Brain Behav Immun (2003) 0.93
The desire to gamble: the influence of outcomes on the priming effects of a gambling episode. J Gambl Stud (2008) 0.93
Social defeat promotes specific cytokine variations within the prefrontal cortex upon subsequent aggressive or endotoxin challenges. Brain Behav Immun (2011) 0.92
Psychosocial stress evoked by a virtual audience: relation to neuroendocrine activity. Cyberpsychol Behav (2007) 0.92
Corticotropin releasing hormone receptor alterations elicited by acute and chronic unpredictable stressor challenges in stressor-susceptible and resilient strains of mice. Behav Brain Res (2007) 0.92
Interplay between pro-inflammatory cytokines and growth factors in depressive illnesses. Front Cell Neurosci (2013) 0.92
Maternal factors and monoamine changes in stress-resilient and susceptible mice: cross-fostering effects. Brain Res (2006) 0.92
Relations between trauma experiences and psychological, physical and neuroendocrine functioning among Somali refugees: mediating role of coping with acculturation stressors. J Immigr Minor Health (2008) 0.91
Impact of chronic intermittent challenges in stressor-susceptible and resilient strains of mice. Biol Psychiatry (2003) 0.91
Psychosocial stressor effects on cortisol and ghrelin in emotional and non-emotional eaters: influence of anger and shame. Horm Behav (2010) 0.91
Altered functional protein networks in the prefrontal cortex and amygdala of victims of suicide. PLoS One (2012) 0.91
Molecular pathway reconstruction and analysis of disturbed gene expression in depressed individuals who died by suicide. PLoS One (2012) 0.91
Spatial and temporal activation of brain regions in hibernation: c-fos expression during the hibernation bout in thirteen-lined ground squirrel. J Comp Neurol (2007) 0.91
Interferon-alpha effects are exaggerated when administered on a psychosocial stressor backdrop: cytokine, corticosterone and brain monoamine variations. J Neuroimmunol (2007) 0.91
The effects of cortisol administration on social status and brain monoaminergic activity in rainbow trout Oncorhynchus mykiss. J Exp Biol (2005) 0.90
Effects of corticosterone on corticotrophin-releasing hormone and gastrin-releasing peptide release in response to an aversive stimulus in two regions of the forebrain (central nucleus of the amygdala and prefrontal cortex). Eur J Neurosci (2008) 0.90
Soothing the threatened brain: leveraging contact comfort with emotionally focused therapy. PLoS One (2013) 0.90
Ethnopharmacology of Q'eqchi' Maya antiepileptic and anxiolytic plants: effects on the GABAergic system. J Ethnopharmacol (2009) 0.90
Early life stress increases anxiety-like behavior in Balb c mice despite a compensatory increase in levels of postnatal maternal care. Horm Behav (2010) 0.90
Inactivation of Pink1 gene in vivo sensitizes dopamine-producing neurons to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and can be rescued by autosomal recessive Parkinson disease genes, Parkin or DJ-1. J Biol Chem (2012) 0.89
Effects of fluoxetine on the reproductive axis of female goldfish (Carassius auratus). Physiol Genomics (2008) 0.88
Sex differences in hormonal responses to a social stressor in chronic major depression. Psychoneuroendocrinology (2009) 0.88
Regional distribution of human trypsinogen 4 in human brain at mRNA and protein level. Neurochem Res (2007) 0.88
Living with the unexplained: coping, distress, and depression among women with chronic fatigue syndrome and/or fibromyalgia compared to an autoimmune disorder. Anxiety Stress Coping (2014) 0.87