PubRank

Peter M Andersen

Author PubWeight™ 126.23‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis. Nat Genet 2009 4.38
2 VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death. Nat Genet 2003 4.19
3 ANG mutations segregate with familial and 'sporadic' amyotrophic lateral sclerosis. Nat Genet 2006 3.88
4 Chromosome 9p21 in sporadic amyotrophic lateral sclerosis in the UK and seven other countries: a genome-wide association study. Lancet Neurol 2010 3.61
5 Genome-wide analysis of single nucleotide polymorphisms uncovers population structure in Northern Europe. PLoS One 2008 3.09
6 Toxicity of familial ALS-linked SOD1 mutants from selective recruitment to spinal mitochondria. Neuron 2004 2.94
7 ITPR2 as a susceptibility gene in sporadic amyotrophic lateral sclerosis: a genome-wide association study. Lancet Neurol 2007 2.80
8 A yeast functional screen predicts new candidate ALS disease genes. Proc Natl Acad Sci U S A 2011 2.68
9 EPHA4 is a disease modifier of amyotrophic lateral sclerosis in animal models and in humans. Nat Med 2012 2.65
10 Disulphide-reduced superoxide dismutase-1 in CNS of transgenic amyotrophic lateral sclerosis models. Brain 2005 2.64
11 Genetic variation in DPP6 is associated with susceptibility to amyotrophic lateral sclerosis. Nat Genet 2007 2.63
12 Smoking and risk for amyotrophic lateral sclerosis: analysis of the EPIC cohort. Ann Neurol 2009 2.56
13 Minute quantities of misfolded mutant superoxide dismutase-1 cause amyotrophic lateral sclerosis. Brain 2003 2.30
14 EFNS guidelines on the clinical management of amyotrophic lateral sclerosis (MALS)--revised report of an EFNS task force. Eur J Neurol 2011 2.27
15 Soluble misfolded subfractions of mutant superoxide dismutase-1s are enriched in spinal cords throughout life in murine ALS models. Proc Natl Acad Sci U S A 2007 1.95
16 Systematically perturbed folding patterns of amyotrophic lateral sclerosis (ALS)-associated SOD1 mutants. Proc Natl Acad Sci U S A 2005 1.94
17 Novel antibodies reveal inclusions containing non-native SOD1 in sporadic ALS patients. PLoS One 2010 1.89
18 ALSOD: the Amyotrophic Lateral Sclerosis Online Database. Amyotroph Lateral Scler 2008 1.89
19 Splice mutation in the iron-sulfur cluster scaffold protein ISCU causes myopathy with exercise intolerance. Am J Hum Genet 2008 1.84
20 Variation in aggregation propensities among ALS-associated variants of SOD1: correlation to human disease. Hum Mol Genet 2009 1.79
21 Minocycline prevents neurotoxicity induced by cerebrospinal fluid from patients with motor neurone disease. Brain 2002 1.71
22 The C9ORF72 expansion mutation is a common cause of ALS+/-FTD in Europe and has a single founder. Eur J Hum Genet 2012 1.71
23 Four familial ALS pedigrees discordant for two SOD1 mutations: are all SOD1 mutations pathogenic? J Neurol Neurosurg Psychiatry 2010 1.68
24 Genome-wide association analyses in Han Chinese identify two new susceptibility loci for amyotrophic lateral sclerosis. Nat Genet 2013 1.57
25 ALSoD: A user-friendly online bioinformatics tool for amyotrophic lateral sclerosis genetics. Hum Mutat 2012 1.45
26 Angiogenin variants in Parkinson disease and amyotrophic lateral sclerosis. Ann Neurol 2011 1.45
27 Ataxin-2 intermediate-length polyglutamine expansions in European ALS patients. Hum Mol Genet 2011 1.24
28 Motor neuron disease in mice expressing the wild type-like D90A mutant superoxide dismutase-1. J Neuropathol Exp Neurol 2006 1.23
29 Amyotrophic lateral sclerosis-associated copper/zinc superoxide dismutase mutations preferentially reduce the repulsive charge of the proteins. J Biol Chem 2007 1.20
30 Overloading of stable and exclusion of unstable human superoxide dismutase-1 variants in mitochondria of murine amyotrophic lateral sclerosis models. J Neurosci 2006 1.18
31 Glial nuclear aggregates of superoxide dismutase-1 are regularly present in patients with amyotrophic lateral sclerosis. Acta Neuropathol 2011 1.13
32 Expression of wild-type human superoxide dismutase-1 in mice causes amyotrophic lateral sclerosis. Hum Mol Genet 2012 1.12
33 The modulation of Amyotrophic Lateral Sclerosis risk by ataxin-2 intermediate polyglutamine expansions is a specific effect. Neurobiol Dis 2011 1.12
34 Age of onset of amyotrophic lateral sclerosis is modulated by a locus on 1p34.1. Neurobiol Aging 2012 1.02
35 Prediagnostic body fat and risk of death from amyotrophic lateral sclerosis: the EPIC cohort. Neurology 2013 1.02
36 D90A-SOD1 mediated amyotrophic lateral sclerosis: a single founder for all cases with evidence for a Cis-acting disease modifier in the recessive haplotype. Hum Mutat 2002 1.02
37 SOD1 gene mutations in ALS patients from British Columbia, Canada: clinical features, neurophysiology and ethical issues in management. Amyotroph Lateral Scler 2008 1.01
38 Chromogranin B P413L variant as risk factor and modifier of disease onset for amyotrophic lateral sclerosis. Proc Natl Acad Sci U S A 2009 1.01
39 Human extraocular muscles in ALS. Invest Ophthalmol Vis Sci 2010 0.99
40 A genome-wide association meta-analysis identifies a novel locus at 17q11.2 associated with sporadic amyotrophic lateral sclerosis. Hum Mol Genet 2013 0.98
41 Swedish population substructure revealed by genome-wide single nucleotide polymorphism data. PLoS One 2011 0.97
42 Optimization of procedures for collecting and storing of CSF for studying the metabolome in ALS. Amyotroph Lateral Scler 2009 0.97
43 No GGGGCC-hexanucleotide repeat expansion in C9ORF72 in parkinsonism patients in Sweden. Amyotroph Lateral Scler Frontotemporal Degener 2012 0.97
44 SOD1 mutations targeting surface hydrogen bonds promote amyotrophic lateral sclerosis without reducing apo-state stability. J Biol Chem 2010 0.96
45 PGC-1α is a male-specific disease modifier of human and experimental amyotrophic lateral sclerosis. Hum Mol Genet 2013 0.96
46 Mapping of gene expression reveals CYP27A1 as a susceptibility gene for sporadic ALS. PLoS One 2012 0.95
47 Age at onset in sod1-mediated amyotrophic lateral sclerosis shows familiality. Neurogenetics 2007 0.95
48 UNC13A is a modifier of survival in amyotrophic lateral sclerosis. Neurobiol Aging 2011 0.95
49 Proteins that bind to misfolded mutant superoxide dismutase-1 in spinal cords from transgenic amyotrophic lateral sclerosis (ALS) model mice. J Biol Chem 2011 0.94
50 Misfolded superoxide dismutase-1 in CSF from amyotrophic lateral sclerosis patients. J Neurochem 2011 0.93
51 A novel optineurin truncating mutation and three glaucoma-associated missense variants in patients with familial amyotrophic lateral sclerosis in Germany. Neurobiol Aging 2012 0.93
52 A novel SOD1 splice site mutation associated with familial ALS revealed by SOD activity analysis. Hum Mol Genet 2010 0.92
53 The human G93A SOD1 phenotype closely resembles sporadic amyotrophic lateral sclerosis. J Neurol Neurosurg Psychiatry 2010 0.92
54 A large genome scan for rare CNVs in amyotrophic lateral sclerosis. Hum Mol Genet 2010 0.92
55 pNfH is a promising biomarker for ALS. Amyotroph Lateral Scler Frontotemporal Degener 2012 0.91
56 Superoxide dismutase-1 and other proteins in inclusions from transgenic amyotrophic lateral sclerosis model mice. J Neurochem 2010 0.91
57 Diffusion tensor imaging in sporadic and familial (D90A SOD1) forms of amyotrophic lateral sclerosis. Arch Neurol 2009 0.89
58 Distinct changes in synaptic protein composition at neuromuscular junctions of extraocular muscles versus limb muscles of ALS donors. PLoS One 2013 0.88
59 Inclusions of amyotrophic lateral sclerosis-linked superoxide dismutase in ventral horns, liver, and kidney. Ann Neurol 2008 0.88
60 ALS patients with mutations in the SOD1 gene have an unique metabolomic profile in the cerebrospinal fluid compared with ALS patients without mutations. Mol Genet Metab 2011 0.87
61 H63D polymorphism in HFE is not associated with amyotrophic lateral sclerosis. Neurobiol Aging 2012 0.87
62 Composition of soluble misfolded superoxide dismutase-1 in murine models of amyotrophic lateral sclerosis. Neuromolecular Med 2012 0.87
63 Mutant superoxide dismutase-1 indistinguishable from wild-type causes ALS. Hum Mol Genet 2012 0.87
64 Volumetric cortical loss in sporadic and familial amyotrophic lateral sclerosis. Amyotroph Lateral Scler 2007 0.86
65 Genomic landscape of positive natural selection in Northern European populations. Eur J Hum Genet 2009 0.86
66 Impact of presymptomatic genetic testing for familial amyotrophic lateral sclerosis. Genet Med 2011 0.85
67 Can lesions to the motor cortex induce amyotrophic lateral sclerosis? J Neurol 2013 0.84
68 Superoxide dismutase in amyotrophic lateral sclerosis patients homozygous for the D90A mutation. Neurobiol Dis 2009 0.84
69 Changes in the spinal cord proteome of an amyotrophic lateral sclerosis murine model determined by differential in-gel electrophoresis. Mol Cell Proteomics 2009 0.84
70 Homozygous SMN2 deletion is a protective factor in the Swedish ALS population. Eur J Hum Genet 2012 0.83
71 C9orf72 and UNC13A are shared risk loci for amyotrophic lateral sclerosis and frontotemporal dementia: a genome-wide meta-analysis. Ann Neurol 2014 0.83
72 Pyrimethamine decreases levels of SOD1 in leukocytes and cerebrospinal fluid of ALS patients: a phase I pilot study. Amyotroph Lateral Scler Frontotemporal Degener 2012 0.82
73 Association of NFE2L2 and KEAP1 haplotypes with amyotrophic lateral sclerosis. Amyotroph Lateral Scler Frontotemporal Degener 2013 0.82
74 Early onset Parkinsonism associated with an intronic SOD1 mutation. Amyotroph Lateral Scler 2012 0.82
75 Two superoxide dismutase prion strains transmit amyotrophic lateral sclerosis-like disease. J Clin Invest 2016 0.82
76 Novel TARDBP mutations in Nordic ALS patients. J Hum Genet 2012 0.82
77 Angiogenin levels and ANG genotypes: dysregulation in amyotrophic lateral sclerosis. PLoS One 2010 0.82
78 Association of APOE with age at onset of sporadic amyotrophic lateral sclerosis. J Neurol Sci 2008 0.82
79 Development of a Smartphone App for a Genetics Website: The Amyotrophic Lateral Sclerosis Online Genetics Database (ALSoD). JMIR Mhealth Uhealth 2013 0.81
80 Analysis of FGGY as a risk factor for sporadic amyotrophic lateral sclerosis. Amyotroph Lateral Scler 2009 0.81
81 Corticomotoneuronal dysfunction in ALS patients with different SOD1 mutations. Clin Neurophysiol 2006 0.81
82 A novel central motor conduction abnormality in D90A-homozygous patients with amyotrophic lateral sclerosis. Muscle Nerve 2004 0.80
83 Sharing of a conserved haplotype suggests a susceptibility gene for multiple sclerosis at chromosome 17p11. Eur J Hum Genet 2002 0.80
84 Different impact of ALS on laminin isoforms in human extraocular muscles versus limb muscles. Invest Ophthalmol Vis Sci 2011 0.80
85 No evidence for shared genetic basis of common variants in multiple sclerosis and amyotrophic lateral sclerosis. Hum Mol Genet 2013 0.80
86 A rare motor neuron deleterious missense mutation in the DPYSL3 (CRMP4) gene is associated with ALS. Hum Mutat 2013 0.80
87 Cortical involvement in four cases of primary lateral sclerosis using [(11)C]-flumazenil PET. J Neurol 2007 0.79
88 Combined fulminant frontotemporal dementia and amyotrophic lateral sclerosis associated with an I113T SOD1 mutation. Amyotroph Lateral Scler 2012 0.78
89 Multi-platform mass spectrometry analysis of the CSF and plasma metabolomes of rigorously matched amyotrophic lateral sclerosis, Parkinson's disease and control subjects. Mol Biosyst 2016 0.78
90 Disease penetrance in amyotrophic lateral sclerosis associated with mutations in the SOD1 gene. Ann Neurol 2004 0.77
91 Aggressive familial ALS with unusual brain MRI and a SOD1 gene mutation. Amyotroph Lateral Scler 2010 0.77
92 [Changing neurology--from diagnostic to therapeutic discipline]. Lakartidningen 2008 0.77
93 No association between VAPB mutations and familial or sporadic ALS in Sweden, Portugal and Iceland. Amyotroph Lateral Scler Frontotemporal Degener 2013 0.76
94 Credibility analysis of putative disease-causing genes using bioinformatics. PLoS One 2013 0.76
95 Ciliary neurotrophic factor genotype does not influence clinical phenotype in amyotrophic lateral sclerosis. Ann Neurol 2003 0.76
96 Progressive aphasia as the presenting symptom in a patient with amyotrophic lateral sclerosis with a novel mutation in the OPTN gene. Amyotroph Lateral Scler Frontotemporal Degener 2013 0.76
97 CuZn-superoxide dismutase in D90A heterozygotes from recessive and dominant ALS pedigrees. Neurobiol Dis 2002 0.76
98 Polymorphisms in the GluR2 gene are not associated with amyotrophic lateral sclerosis. Neurobiol Aging 2010 0.76
99 Screening of hypoxia-inducible genes in sporadic ALS. Amyotroph Lateral Scler 2008 0.75
100 [Representantives of the Swedish Neurological Association: Swedish neurology needs strong resource reinforcement]. Lakartidningen 2008 0.75
101 G127R: A novel SOD1 mutation associated with rapidly evolving ALS and severe pain syndrome. Amyotroph Lateral Scler 2010 0.75
102 DNA sequence analysis of the conserved region around the SOD1 gene locus in recessively inherited ALS. Neurosci Lett 2009 0.75
103 Variants in candidate ALS modifier genes linked to Cu/Zn superoxide dismutase do not explain divergent survival phenotypes. Neurosci Lett 2005 0.75