Published in Bioorg Med Chem on April 03, 2010
Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation. Nature (2006) 9.36
Complete sequencing and characterization of 21,243 full-length human cDNAs. Nat Genet (2003) 7.98
Clinical outcomes of double-balloon endoscopy for the diagnosis and treatment of small-intestinal diseases. Clin Gastroenterol Hepatol (2004) 3.04
The impact of anti-HLA antibodies on unrelated cord blood transplantations. Blood (2010) 2.05
HIV entry inhibitor TAK-779 attenuates atherogenesis in low-density lipoprotein receptor-deficient mice. Arterioscler Thromb Vasc Biol (2005) 1.66
Lowering bile acid pool size with a synthetic farnesoid X receptor (FXR) agonist induces obesity and diabetes through reduced energy expenditure. J Biol Chem (2011) 1.62
Resistive index as risk factor for acute urinary retention in patients with benign prostatic hyperplasia. Urology (2010) 1.46
Mapping a quantitative trait locus for resistance to bacterial grain rot in rice. Rice (N Y) (2013) 1.45
Analysis of the full-length genome of a hepatitis E virus isolate obtained from a wild boar in Japan that is classifiable into a novel genotype. J Gen Virol (2011) 1.44
Efficacy and safety of once-daily oxybutynin patch versus placebo and propiverine in Japanese patients with overactive bladder: A randomized double-blind trial. Int J Urol (2013) 1.42
Unexpectedly high prevalence of pretransplant abnormal glucose tolerance in pediatric kidney transplant recipients. Pediatr Transplant (2006) 1.41
Arteriosclerosis related factors had no clinical significant correlation with resistive index in symptomatic benign prostatic hyperplasia. Urology (2010) 1.39
Urinary trypsin inhibitor protects against systemic inflammation induced by lipopolysaccharide. Mol Pharmacol (2004) 1.32
Design, synthesis, and properties of 2',4'-BNA(NC): a bridged nucleic acid analogue. J Am Chem Soc (2008) 1.30
Nongenomic actions of bile acids. Synthesis and preliminary characterization of 23- and 6,23-alkyl-substituted bile acid derivatives as selective modulators for the G-protein coupled receptor TGR5. J Med Chem (2007) 1.28
Clinical outcomes of enteroscopy using the double-balloon method for strictures of the small intestine. World J Gastroenterol (2005) 1.17
The unique target specificity of a nonpeptide chemokine receptor antagonist: selective blockade of two Th1 chemokine receptors CCR5 and CXCR3. J Leukoc Biol (2003) 1.17
A non-peptide CCR5 antagonist inhibits collagen-induced arthritis by modulating T cell migration without affecting anti-collagen T cell responses. Eur J Immunol (2002) 1.17
Effects of diet-induced moderate weight reduction on intrahepatic and intramyocellular triglycerides and glucose metabolism in obese subjects. J Clin Endocrinol Metab (2007) 1.16
Role of CCR1 and CCR5 in homing and growth of multiple myeloma and in the development of osteolytic lesions: a study in the 5TMM model. Clin Exp Metastasis (2006) 1.16
Effects on RNA interference in gene expression (RNAi) in cultured mammalian cells of mismatches and the introduction of chemical modifications at the 3'-ends of siRNAs. Antisense Nucleic Acid Drug Dev (2002) 1.15
BNAs: novel nucleic acid analogs with a bridged sugar moiety. Chem Commun (Camb) (2002) 1.11
2'-O,4'-C-ethylene-bridged nucleic acids (ENA): highly nuclease-resistant and thermodynamically stable oligonucleotides for antisense drug. Bioorg Med Chem Lett (2002) 1.10
Protection against oxidative stress-induced hepatic injury by intracellular type II platelet-activating factor acetylhydrolase by metabolism of oxidized phospholipids in vivo. J Biol Chem (2007) 1.10
Iron (III) induces aggregation of hyperphosphorylated tau and its reduction to iron (II) reverses the aggregation: implications in the formation of neurofibrillary tangles of Alzheimer's disease. J Neurochem (2002) 1.09
Human parvovirus B19 nonstructural protein (NS1) induces cell cycle arrest at G(1) phase. J Virol (2003) 1.08
Survival of parvovirus B19-infected cells by cellular autophagy. Virology (2006) 1.08
L-Glutamine or L-alanyl-L-glutamine prevents oxidant- or endotoxin-induced death of neonatal enterocytes. Amino Acids (2009) 1.06
Nonsurgical management of small-bowel polyps in Peutz-Jeghers syndrome with extensive polypectomy by using double-balloon endoscopy. Gastrointest Endosc (2011) 1.05
Sibling cases of Vici syndrome: sleep abnormalities and complications of renal tubular acidosis. Am J Med Genet A (2007) 1.03
Protective role of urinary trypsin inhibitor in acute lung injury induced by lipopolysaccharide. Exp Biol Med (Maywood) (2005) 1.01
Clinical features of late cytomegalovirus infection after hematopoietic stem cell transplantation. Int J Hematol (2008) 1.01
[QTL analysis of sheath blight resistance in rice (Oryza sativa L.)]. Yi Chuan Xue Bao (2002) 1.00
Bile acid binding resin improves metabolic control through the induction of energy expenditure. PLoS One (2012) 0.99
Total synthesis of an antitumor antibiotic, Fostriecin (CI-920). J Am Chem Soc (2003) 0.97
Non-steroidal anti-inflammatory drug-induced small bowel injuries identified by double-balloon endoscopy. World J Gastroenterol (2005) 0.95
Long-term ultra-low-dose acyclovir against varicella-zoster virus reactivation after allogeneic hematopoietic stem cell transplantation. Am J Hematol (2008) 0.94
Synthesis and properties of 2'-O,4'-C-ethylene-bridged nucleic acids (ENA) as effective antisense oligonucleotides. Bioorg Med Chem (2003) 0.93
Antisense drug discovery and development. Future Med Chem (2011) 0.91
Triplex formation with 2'-O,4'-C-ethylene-bridged nucleic acids (ENA) having C3'-endo conformation at physiological pH. Nucleic Acids Res (2003) 0.90
Systematic analysis of enzymatic DNA polymerization using oligo-DNA templates and triphosphate analogs involving 2',4'-bridged nucleosides. Nucleic Acids Res (2008) 0.90
Concentration-dependent inhibitory effect of irbesartan on renal uric acid transporters. J Pharmacol Sci (2010) 0.90
Relationship between exercise tolerance and muscle strength following cardiac rehabilitation: comparison of patients after cardiac surgery and patients with myocardial infarction. J Cardiol (2009) 0.90
The origin of neoplastic mast cells in systemic mastocytosis with AML1/ETO-positive acute myeloid leukemia. Exp Hematol (2007) 0.89
Increased expression of macrophage-inducible C-type lectin in adipose tissue of obese mice and humans. Diabetes (2011) 0.89
Total synthesis of leustroducsin B. J Org Chem (2008) 0.89
Increased expression of periostin in vitreous and fibrovascular membranes obtained from patients with proliferative diabetic retinopathy. Invest Ophthalmol Vis Sci (2011) 0.89
HSP90, HSP70, and GAPDH directly interact with the cytoplasmic domain of macrophage scavenger receptors. Biochem Biophys Res Commun (2002) 0.89
Synthesis and properties of 2'-O,4'-C-methyleneoxymethylene bridged nucleic acid. Bioorg Med Chem (2005) 0.88
Mapping and validation of QTLs for rice sheath blight resistance. Breed Sci (2013) 0.88
N-Methyl substituted 2',4'- BNANC: a highly nuclease-resistant nucleic acid analogue with high-affinity RNA selective hybridization. Chem Commun (Camb) (2007) 0.88
Double-balloon enteroscopy through a Roux-en-Y anastomosis for EMR of an early carcinoma in the afferent duodenal limb. Gastrointest Endosc (2004) 0.88
A nationwide survey of hepatitis E virus (HEV) infection in wild boars in Japan: identification of boar HEV strains of genotypes 3 and 4 and unrecognized genotypes. Arch Virol (2011) 0.87
Highly stable pyrimidine-motif triplex formation at physiological pH values by a bridged nucleic acid analogue. Angew Chem Int Ed Engl (2007) 0.87
Conformations and dynamics of Ets-1 ETS domain-DNA complexes. Proc Natl Acad Sci U S A (2003) 0.86
Cholesterol-lowering Action of BNA-based Antisense Oligonucleotides Targeting PCSK9 in Atherogenic Diet-induced Hypercholesterolemic Mice. Mol Ther Nucleic Acids (2012) 0.86
Antioxidative role of urinary trypsin inhibitor in acute lung injury induced by lipopolysaccharide. Int J Mol Med (2005) 0.86
Decreased incidence of acute graft-versus-host disease by continuous infusion of cyclosporine with a higher target blood level. Am J Hematol (2008) 0.86
Urinary trypsin inhibitor protects against liver injury and coagulation pathway dysregulation induced by lipopolysaccharide/D-galactosamine in mice. Lab Invest (2009) 0.86
The butenolide signaling molecules SRB1 and SRB2 induce lankacidin and lankamycin production in Streptomyces rochei. Chembiochem (2012) 0.85
Stable lariat formation based on a G-quadruplex scaffold. J Am Chem Soc (2008) 0.85
Regression of the tumor after withdrawal of cyclosporine in relapsed extranodal natural killer/T cell lymphoma following allogeneic hematopoietic stem cell transplantation. Am J Hematol (2007) 0.85
Long-term Outcomes in Patients with Small Intestinal Strictures Secondary to Crohn's Disease After Double-balloon Endoscopy-assisted Balloon Dilation. Inflamm Bowel Dis (2016) 0.84
Synthesis and base-pairing properties of C-nucleotides having 1-substituted 1H-1,2,3-triazoles. Bioorg Med Chem Lett (2009) 0.84
Protective role of urinary trypsin inhibitor in lung expression of proinflammatory cytokines accompanied by lethal liver injury in mice. Immunopharmacol Immunotoxicol (2009) 0.84
False-positive Aspergillus galactomannan antigenaemia after haematopoietic stem cell transplantation. J Antimicrob Chemother (2007) 0.84
Development of multidrug resistance due to multiple factors including P-glycoprotein overexpression under K-selection after MYC and HRAS oncogene activation. Int J Cancer (2006) 0.84
Efficacy of intravitreal bevacizumab (Avastin) for short-term treatment of diabetic macular edema. J Med Invest (2009) 0.84
2',4'-BNA/LNA aptamers: CE-SELEX using a DNA-based library of full-length 2'-O,4'-C-methylene-bridged/linked bicyclic ribonucleotides. Bioorg Med Chem Lett (2013) 0.84
Characteristics of aggressive variants in T1a renal cell carcinoma. J Cancer Res Clin Oncol (2011) 0.83
Presumptive treatment strategy for aspergillosis in allogeneic haematopoietic stem cell transplant recipients. J Antimicrob Chemother (2007) 0.83
A bridged nucleic acid, 2',4'-BNA COC: synthesis of fully modified oligonucleotides bearing thymine, 5-methylcytosine, adenine and guanine 2',4'-BNA COC monomers and RNA-selective nucleic-acid recognition. Nucleic Acids Res (2009) 0.83
Hepatitis C virus core protein binds to a C-terminal region of NS5B RNA polymerase. Hepatol Res (2002) 0.83
Accurate evaluation of the absorption maxima of retinal proteins based on a hybrid QM/MM method. J Comput Chem (2006) 0.83
Superior Silencing by 2',4'-BNA(NC)-Based Short Antisense Oligonucleotides Compared to 2',4'-BNA/LNA-Based Apolipoprotein B Antisense Inhibitors. J Nucleic Acids (2012) 0.83
A pivotal role for CC chemokine receptor 5 in T-cell migration to tumor sites induced by interleukin 12 treatment in tumor-bearing mice. Cancer Res (2002) 0.83
Stoichiometry-focused (18)F-labeling of alkyne-substituted oligodeoxynucleotides using azido([(18)F]fluoromethyl)benzenes by Cu-catalyzed Huisgen reaction. Bioorg Med Chem (2010) 0.82
2',4'-BNA(NC): a novel bridged nucleic acid analogue with excellent hybridizing and nuclease resistance profiles. Nucleosides Nucleotides Nucleic Acids (2007) 0.82
Two cases of subungual melanoma in situ. J Dermatol (2008) 0.82