Published in Environ Health Perspect on May 01, 2010
NADPH oxidase activation is required in reactive oxygen species generation and cell transformation induced by hexavalent chromium. Toxicol Sci (2011) 1.05
Arsenic exposure inhibits myogenesis and neurogenesis in P19 stem cells through repression of the β-catenin signaling pathway. Toxicol Sci (2012) 0.84
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Direct binding of arsenic trioxide to AMPK and generation of inhibitory effects on acute myeloid leukemia precursors. Mol Cancer Ther (2014) 0.80
Receptor-interacting protein 140 overexpression promotes neuro-2a neuronal differentiation by ERK1/2 signaling. Chin Med J (Engl) (2015) 0.78
Arsenic inhibits hedgehog signaling during P19 cell differentiation. Toxicol Appl Pharmacol (2014) 0.77
AMPK interacts with DSCAM and plays an important role in netrin-1 induced neurite outgrowth. Protein Cell (2013) 0.76
Hijacking microglial glutathione by inorganic arsenic impels bystander death of immature neurons through extracellular cystine/glutamate imbalance. Sci Rep (2016) 0.75
Netrin-1 Improves Functional Recovery through Autophagy Regulation by Activating the AMPK/mTOR Signaling Pathway in Rats with Spinal Cord Injury. Sci Rep (2017) 0.75
Arsenic inhibits stem cell differentiation by altering the interplay between the Wnt3a and Notch signaling pathways. Toxicol Rep (2016) 0.75
Differential epigenetic effects of chlorpyrifos and arsenic in proliferating and differentiating human neural progenitor cells. Reprod Toxicol (2016) 0.75
Prenatal arsenic exposure alters REST/NRSF and microRNA regulators of embryonic neural stem cell fate in a sex-dependent manner. Neurotoxicol Teratol (2016) 0.75
Cyanotoxins at low doses induce apoptosis and inflammatory effects in murine brain cells: Potential implications for neurodegenerative diseases. Toxicol Rep (2016) 0.75
The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress. Proc Natl Acad Sci U S A (2004) 12.30
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Developmental neurotoxicity of industrial chemicals. Lancet (2006) 7.37
Resveratrol stimulates AMP kinase activity in neurons. Proc Natl Acad Sci U S A (2007) 4.24
MO25alpha/beta interact with STRADalpha/beta enhancing their ability to bind, activate and localize LKB1 in the cytoplasm. EMBO J (2003) 3.77
Energy-dependent regulation of cell structure by AMP-activated protein kinase. Nature (2007) 3.71
Growth suppression by Lkb1 is mediated by a G(1) cell cycle arrest. Proc Natl Acad Sci U S A (1999) 3.46
LKB1/STRAD promotes axon initiation during neuronal polarization. Cell (2007) 3.25
AMP-activated protein kinase: an ultrasensitive system for monitoring cellular energy charge. Biochem J (1999) 2.75
Phosphorylation of LKB1 at serine 428 by protein kinase C-zeta is required for metformin-enhanced activation of the AMP-activated protein kinase in endothelial cells. Circulation (2008) 2.48
Oxidative mechanism of arsenic toxicity and carcinogenesis. Mol Cell Biochem (2004) 2.07
Activation of protein kinase C zeta by peroxynitrite regulates LKB1-dependent AMP-activated protein kinase in cultured endothelial cells. J Biol Chem (2006) 1.98
The regulation of AMP-activated protein kinase by upstream kinases. Int J Obes (Lond) (2008) 1.98
Arsenic contamination in groundwater: a global perspective with emphasis on the Asian scenario. J Health Popul Nutr (2006) 1.81
Purification and identification of secreted oxidative stress-induced factors from vascular smooth muscle cells. J Biol Chem (2000) 1.68
The neurodegeneration mutant löchrig interferes with cholesterol homeostasis and Appl processing. EMBO J (2002) 1.65
AMP-activated protein kinase phosphorylates retinoblastoma protein to control mammalian brain development. Dev Cell (2009) 1.44
Protein kinase Czeta-dependent LKB1 serine 428 phosphorylation increases LKB1 nucleus export and apoptosis in endothelial cells. J Biol Chem (2008) 1.31
LKB1 regulates neuronal migration and neuronal differentiation in the developing neocortex through centrosomal positioning. J Neurosci (2007) 1.22
Resveratrol promotes osteogenic differentiation and protects against dexamethasone damage in murine induced pluripotent stem cells. Stem Cells Dev (2010) 1.17
Reactive oxygen species modulate the differentiation of neurons in clonal cortical cultures. Mol Cell Neurosci (2006) 1.15
Cyanidin-3-glucoside reverses ethanol-induced inhibition of neurite outgrowth: role of glycogen synthase kinase 3 Beta. Neurotox Res (2009) 1.02
NOX1/NADPH oxidase negatively regulates nerve growth factor-induced neurite outgrowth. Free Radic Biol Med (2006) 1.02
Reactive oxygen species regulate F-actin dynamics in neuronal growth cones and neurite outgrowth. J Neurochem (2008) 1.02
Activation of double-stranded RNA-activated protein kinase by mild impairment of oxidative metabolism in neurons. J Neurochem (2007) 1.01
Drosophila alicorn is a neuronal maintenance factor protecting against activity-induced retinal degeneration. J Neurosci (2008) 0.98
Microtubule reconfiguration during axonal retraction induced by nitric oxide. J Neurosci (2002) 0.96
Preliminary morphological and morphometric study of rat cerebellum following sodium arsenite exposure during rapid brain growth (RBG) period. Toxicology (2007) 0.91
The PC12 cell as a model for studies of the mechanism of induction of peripheral neuropathy by anti-HIV-1 dideoxynucleoside analogs. Biochem Pharmacol (1991) 0.90
Co-application of arsenic trioxide (As2O3) and cisplatin (CDDP) on human SY-5Y neuroblastoma cells has differential effects on the intracellular calcium concentration ([Ca2+]i) and cytotoxicity. Neurotoxicology (2008) 0.89
Arsenic exposure disrupts neurite growth and complexity in vitro. Neurotoxicology (2009) 0.87
Arsenic trioxide concentration determines the fate of Ewing's sarcoma family tumors and neuroblastoma cells in vitro. FEBS Lett (2006) 0.84
Decreased nitric oxide markers and morphological changes in the brain of arsenic-exposed rats. Toxicology (2009) 0.81
Defective neurite outgrowth in aphidicolin/cAMP-induced motor neurons expressing mutant Cu/Zn superoxide dismutase. Int J Dev Neurosci (2002) 0.79
Arsenic inhibits neurofilament transport and induces perikaryal accumulation of phosphorylated neurofilaments: roles of JNK and GSK-3beta. Brain Res (2007) 0.78
High-thermoelectric performance of nanostructured bismuth antimony telluride bulk alloys. Science (2008) 7.34
TLR4 activation mediates kidney ischemia/reperfusion injury. J Clin Invest (2007) 4.77
SIRT1 improves insulin sensitivity under insulin-resistant conditions by repressing PTP1B. Cell Metab (2007) 4.75
Analysis of optical absorption in silicon nanowire arrays for photovoltaic applications. Nano Lett (2007) 4.27
Bidirectional expression of CUG and CAG expansion transcripts and intranuclear polyglutamine inclusions in spinocerebellar ataxia type 8. Nat Genet (2006) 3.87
Trouble at rest: how correlation patterns and group differences become distorted after global signal regression. Brain Connect (2012) 3.73
Cross-regulation between Notch and p63 in keratinocyte commitment to differentiation. Genes Dev (2006) 3.72
Differential expression of microRNA species in human gastric cancer versus non-tumorous tissues. J Gastroenterol Hepatol (2008) 3.65
Amygdala and ventrolateral prefrontal cortex activation to masked angry faces in children and adolescents with generalized anxiety disorder. Arch Gen Psychiatry (2008) 3.22
Sustained axon regeneration induced by co-deletion of PTEN and SOCS3. Nature (2011) 3.18
Enrollment of elderly patients in clinical trials for cancer drug registration: a 7-year experience by the US Food and Drug Administration. J Clin Oncol (2004) 3.18
Soluble amyloid beta-protein dimers isolated from Alzheimer cortex directly induce Tau hyperphosphorylation and neuritic degeneration. Proc Natl Acad Sci U S A (2011) 3.11
A selective filter for cytoplasmic transport at the axon initial segment. Cell (2009) 3.09
High-performance flat-panel solar thermoelectric generators with high thermal concentration. Nat Mater (2011) 2.96
A new method for improving functional-to-structural MRI alignment using local Pearson correlation. Neuroimage (2008) 2.94
Ventrolateral prefrontal cortex activation and attentional bias in response to angry faces in adolescents with generalized anxiety disorder. Am J Psychiatry (2006) 2.90
Stromal control of cystine metabolism promotes cancer cell survival in chronic lymphocytic leukaemia. Nat Cell Biol (2012) 2.59
Approval summary for imatinib mesylate capsules in the treatment of chronic myelogenous leukemia. Clin Cancer Res (2002) 2.56
FDA drug approval summary: gefitinib (ZD1839) (Iressa) tablets. Oncologist (2003) 2.53
United States Food and Drug Administration Drug Approval summary: Gefitinib (ZD1839; Iressa) tablets. Clin Cancer Res (2004) 2.43
Association analyses identify six new psoriasis susceptibility loci in the Chinese population. Nat Genet (2010) 2.41
Regulated ATP release from astrocytes through lysosome exocytosis. Nat Cell Biol (2007) 2.38
Amygdala and ventrolateral prefrontal cortex function during anticipated peer evaluation in pediatric social anxiety. Arch Gen Psychiatry (2008) 2.37
[(18)F]T807, a novel tau positron emission tomography imaging agent for Alzheimer's disease. Alzheimers Dement (2013) 2.31
An analysis of the indications for cesarean section in a teaching hospital in China. Eur J Obstet Gynecol Reprod Biol (2013) 2.26
Design and analysis of non-inferiority mortality trials in oncology. Stat Med (2003) 2.24
Autophagy is a renoprotective mechanism during in vitro hypoxia and in vivo ischemia-reperfusion injury. Am J Pathol (2010) 2.24
Iloprost attenuates doxorubicin-induced cardiac injury in a murine model without compromising tumour suppression. Eur Heart J (2006) 2.13
The host type I interferon response to viral and bacterial infections. Cell Res (2005) 2.12
Oxidative mechanism of arsenic toxicity and carcinogenesis. Mol Cell Biochem (2004) 2.07
Abnormal ventromedial prefrontal cortex function in children with psychopathic traits during reversal learning. Arch Gen Psychiatry (2008) 2.06
Approval summary: imatinib mesylate in the treatment of metastatic and/or unresectable malignant gastrointestinal stromal tumors. Clin Cancer Res (2002) 2.06
Cyclophilin A/Cluster of Differentiation 147 Interactions Participate in Early Brain Injury After Subarachnoid Hemorrhage in Rats. Crit Care Med (2015) 2.01
Enhanced thermoelectric figure-of-merit in nanostructured p-type silicon germanium bulk alloys. Nano Lett (2008) 1.97
SPDEF regulates goblet cell hyperplasia in the airway epithelium. J Clin Invest (2007) 1.96
InterDom: a database of putative interacting protein domains for validating predicted protein interactions and complexes. Nucleic Acids Res (2003) 1.94
Most antiviral CD8 T cells during chronic viral infection do not express high levels of perforin and are not directly cytotoxic. Blood (2002) 1.94
A genome-wide association study identifies two new risk loci for Graves' disease. Nat Genet (2011) 1.92
Sensitive capture of circulating tumour cells by functionalized graphene oxide nanosheets. Nat Nanotechnol (2013) 1.92
Resveratrol scavenges reactive oxygen species and effects radical-induced cellular responses. Biochem Biophys Res Commun (2003) 1.91
AKT1 amplification regulates cisplatin resistance in human lung cancer cells through the mammalian target of rapamycin/p70S6K1 pathway. Cancer Res (2007) 1.85
G1 cell cycle progression and the expression of G1 cyclins are regulated by PI3K/AKT/mTOR/p70S6K1 signaling in human ovarian cancer cells. Am J Physiol Cell Physiol (2004) 1.85
Airway epithelial transcription factor NK2 homeobox 1 inhibits mucous cell metaplasia and Th2 inflammation. Am J Respir Crit Care Med (2011) 1.84
Surgical management of thymic epithelial tumors: a retrospective review of 204 cases. Ann Thorac Surg (2005) 1.82
Meta-analysis confirms the LCE3C_LCE3B deletion as a risk factor for psoriasis in several ethnic groups and finds interaction with HLA-Cw6. J Invest Dermatol (2010) 1.82
Complete response correlates with long-term survival and progression-free survival in high-dose therapy in multiple myeloma. Haematologica (2007) 1.82
Role of PI3K/AKT/mTOR signaling in the cell cycle progression of human prostate cancer. Biochem Biophys Res Commun (2003) 1.82
Modifying the DPClus algorithm for identifying protein complexes based on new topological structures. BMC Bioinformatics (2008) 1.81
Disposable circumcision suture device: clinical effect and patient satisfaction. Asian J Androl (2014) 1.81
Performance comparison and evaluation of software tools for microRNA deep-sequencing data analysis. Nucleic Acids Res (2012) 1.80
Pulse accumulation, radial heat conduction, and anisotropic thermal conductivity in pump-probe transient thermoreflectance. Rev Sci Instrum (2008) 1.80
Cyanidin-3-glucoside, a natural product derived from blackberry, exhibits chemopreventive and chemotherapeutic activity. J Biol Chem (2006) 1.78
The Urban Resident Basic Medical Insurance: a landmark reform towards universal coverage in China. Health Econ (2009) 1.74
Contextual fear conditioning in humans: cortical-hippocampal and amygdala contributions. J Neurosci (2008) 1.72
K-ras(G12V) transformation leads to mitochondrial dysfunction and a metabolic switch from oxidative phosphorylation to glycolysis. Cell Res (2011) 1.72
Adolescents, adults and rewards: comparing motivational neurocircuitry recruitment using fMRI. PLoS One (2010) 1.70
Genome-wide association study for vitiligo identifies susceptibility loci at 6q27 and the MHC. Nat Genet (2010) 1.69
Patterns of neural connectivity during an attention bias task moderate associations between early childhood temperament and internalizing symptoms in young adulthood. Biol Psychiatry (2013) 1.68
Glycogen synthase kinase 3beta (GSK3beta) mediates 6-hydroxydopamine-induced neuronal death. FASEB J (2004) 1.68
Optical absorption enhancement in silicon nanohole arrays for solar photovoltaics. Nano Lett (2010) 1.66
Molecular mechanisms of arsenic carcinogenesis. Mol Cell Biochem (2004) 1.66
Tunable spin-orbit coupling and quantum phase transition in a trapped Bose-Einstein condensate. Sci Rep (2013) 1.66
Retracted Epithelial mesenchymal transition is required for acquisition of anoikis resistance and metastatic potential in adenoid cystic carcinoma. PLoS One (2012) 1.64
Experimental studies on anisotropic thermoelectric properties and structures of n-type Bi2Te2.7Se0.3. Nano Lett (2010) 1.63
Surface phonon polaritons mediated energy transfer between nanoscale gaps. Nano Lett (2009) 1.63
Integrative approach for computationally inferring protein domain interactions. Bioinformatics (2003) 1.63
Curcumin, a dietary component, has anticancer, chemosensitization, and radiosensitization effects by down-regulating the MDM2 oncogene through the PI3K/mTOR/ETS2 pathway. Cancer Res (2007) 1.60
Prevalence of hypertension in china: a cross-sectional study. PLoS One (2013) 1.60
Metal-induced oxidative stress and signal transduction. Free Radic Biol Med (2004) 1.59
Evaluation of biocompatibility of polypyrrole in vitro and in vivo. J Biomed Mater Res A (2004) 1.59
Flavoprotein autofluorescence imaging of neuronal activation in the cerebellar cortex in vivo. J Neurophysiol (2004) 1.58
Genome-wide association analyses in Han Chinese identify two new susceptibility loci for amyotrophic lateral sclerosis. Nat Genet (2013) 1.57
A highly selective and specific PET tracer for imaging of tau pathologies. J Alzheimers Dis (2012) 1.56
HIV/AIDS knowledge, attitudes and behaviors assessment of Chinese students: a questionnaire study. Int J Environ Res Public Health (2007) 1.56
High thermal conductivity of single polyethylene chains using molecular dynamics simulations. Phys Rev Lett (2008) 1.56
Constructing molecular classifiers for the accurate prognosis of lung adenocarcinoma. Clin Cancer Res (2006) 1.55
Phasic and sustained fear in humans elicits distinct patterns of brain activity. Neuroimage (2010) 1.55
Coherent phonon heat conduction in superlattices. Science (2012) 1.53
Direct measurement of room-temperature nondiffusive thermal transport over micron distances in a silicon membrane. Phys Rev Lett (2013) 1.53
Cytoplasm-localized SIRT1 enhances apoptosis. J Cell Physiol (2007) 1.52
Control of basal autophagy by calpain1 mediated cleavage of ATG5. Autophagy (2010) 1.51
Confirmation of gene expression-based prediction of survival in non-small cell lung cancer. Clin Cancer Res (2008) 1.49
PI3K induced actin filament remodeling through Akt and p70S6K1: implication of essential role in cell migration. Am J Physiol Cell Physiol (2003) 1.49
Eight-year follow-up of the 90,000-person Haimen City cohort: I. Hepatocellular carcinoma mortality, risk factors, and gender differences. Cancer Epidemiol Biomarkers Prev (2002) 1.49
Glucuronidation of active tamoxifen metabolites by the human UDP glucuronosyltransferases. Drug Metab Dispos (2007) 1.48
Efficient light trapping in inverted nanopyramid thin crystalline silicon membranes for solar cell applications. Nano Lett (2012) 1.48
Apigenin inhibits expression of vascular endothelial growth factor and angiogenesis in human lung cancer cells: implication of chemoprevention of lung cancer. Mol Pharmacol (2005) 1.47
Influence of simvastatin on microthrombosis in the brain after subarachnoid hemorrhage in rats: a preliminary study. Ann Clin Lab Sci (2010) 1.47
SENP3-mediated deSUMOylation of dynamin-related protein 1 promotes cell death following ischaemia. EMBO J (2013) 1.47
Genome-wide association study identifies two new susceptibility loci for atopic dermatitis in the Chinese Han population. Nat Genet (2011) 1.46
ILK mediates actin filament rearrangements and cell migration and invasion through PI3K/Akt/Rac1 signaling. Oncogene (2005) 1.46
Procedural arrhythmia termination and long-term single-procedure clinical outcome in patients with non-paroxysmal atrial fibrillation. J Cardiovasc Electrophysiol (2013) 1.45
Cerebellar cortical molecular layer inhibition is organized in parasagittal zones. J Neurosci (2006) 1.44
Glutamine preconditioning protects against tourniquet-induced local and distant organ injury in a rodent ischemia-reperfusion model. Acta Orthop (2007) 1.43
Right ventricular outflow pacing induces less regional wall motion abnormalities in the left ventricle compared with apical pacing. Europace (2011) 1.42
A Shope Fibroma virus PYRIN-only protein modulates the host immune response. Virus Genes (2007) 1.41
Vanadate-induced expression of hypoxia-inducible factor 1 alpha and vascular endothelial growth factor through phosphatidylinositol 3-kinase/Akt pathway and reactive oxygen species. J Biol Chem (2002) 1.41