Microvesicles: mediators of extracellular communication during cancer progression.

PubWeight™: 3.35‹?› | Rank: Top 1%

🔗 View Article (PMC 2864708)

Published in J Cell Sci on May 15, 2010

Authors

Vandhana Muralidharan-Chari1, James W Clancy, Alanna Sedgwick, Crislyn D'Souza-Schorey

Author Affiliations

1: Department of Biological Sciences, University of Notre Dame, Notre Dame, IN 46556-0369, USA.

Articles citing this

(truncated to the top 100)

Extracellular vesicles: exosomes, microvesicles, and friends. J Cell Biol (2013) 10.02

Membrane vesicles, current state-of-the-art: emerging role of extracellular vesicles. Cell Mol Life Sci (2011) 5.42

Contribution of platelets to tumour metastasis. Nat Rev Cancer (2011) 4.16

Microvesicles as mediators of intercellular communication in cancer--the emerging science of cellular 'debris'. Semin Immunopathol (2011) 2.78

Extracellular microRNA: a new source of biomarkers. Mutat Res (2011) 2.55

Malaria-infected erythrocyte-derived microvesicles mediate cellular communication within the parasite population and with the host immune system. Cell Host Microbe (2013) 2.29

Tumor-derived microvesicles: shedding light on novel microenvironment modulators and prospective cancer biomarkers. Genes Dev (2012) 2.22

Tumour-secreted miR-9 promotes endothelial cell migration and angiogenesis by activating the JAK-STAT pathway. EMBO J (2012) 2.21

Exosome/microvesicle-mediated epigenetic reprogramming of cells. Am J Cancer Res (2010) 1.96

Macrophage microvesicles induce macrophage differentiation and miR-223 transfer. Blood (2012) 1.80

Biodegradable silicon nanoneedles delivering nucleic acids intracellularly induce localized in vivo neovascularization. Nat Mater (2015) 1.65

Functional microRNA is transferred between glioma cells. Cancer Res (2010) 1.63

Selective extracellular vesicle-mediated export of an overlapping set of microRNAs from multiple cell types. BMC Genomics (2012) 1.58

Circulating miRNAs: cell-cell communication function? Front Genet (2013) 1.55

Horizontal transfer of microRNAs: molecular mechanisms and clinical applications. Protein Cell (2012) 1.49

Role of exosomes/microvesicles in the nervous system and use in emerging therapies. Front Physiol (2012) 1.49

Inflammatory processes in cardiovascular disease: a route to targeted therapies. Nat Rev Cardiol (2016) 1.46

Expression profiling of cancerous and normal breast tissues identifies microRNAs that are differentially expressed in serum from patients with (metastatic) breast cancer and healthy volunteers. Breast Cancer Res (2012) 1.39

Impact of biofluid viscosity on size and sedimentation efficiency of the isolated microvesicles. Front Physiol (2012) 1.36

Exosomes: mediators of neurodegeneration, neuroprotection and therapeutics. Mol Neurobiol (2013) 1.32

Extracellular vesicles as an emerging mechanism of cell-to-cell communication. Endocrine (2012) 1.32

Differential fates of biomolecules delivered to target cells via extracellular vesicles. Proc Natl Acad Sci U S A (2015) 1.27

Exosome mimetics: a novel class of drug delivery systems. Int J Nanomedicine (2012) 1.27

Extracellular vesicles in cancer: exosomes, microvesicles and the emerging role of large oncosomes. Semin Cell Dev Biol (2015) 1.23

Effect of exosomes derived from multipluripotent mesenchymal stromal cells on functional recovery and neurovascular plasticity in rats after traumatic brain injury. J Neurosurg (2015) 1.22

Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis. Proc Natl Acad Sci U S A (2014) 1.21

Extracellular communication via microRNA: lipid particles have a new message. J Lipid Res (2013) 1.17

Oncogenic extracellular vesicles in brain tumor progression. Front Physiol (2012) 1.15

Circulating microparticles: square the circle. BMC Cell Biol (2013) 1.14

Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes. Oncotarget (2015) 1.13

MicroRNAs as potential biomarkers in cancer: opportunities and challenges. Biomed Res Int (2015) 1.12

In-depth characterization of the secretome of colorectal cancer metastatic cells identifies key proteins in cell adhesion, migration, and invasion. Mol Cell Proteomics (2013) 1.11

Dynamic physical properties of dissociated tumor cells revealed by dielectrophoretic field-flow fractionation. Integr Biol (Camb) (2011) 1.11

Extracellular vesicles release by cardiac telocytes: electron microscopy and electron tomography. J Cell Mol Med (2014) 1.10

The small GTPase ARF6 stimulates β-catenin transcriptional activity during WNT5A-mediated melanoma invasion and metastasis. Sci Signal (2013) 1.10

Exosomes released from human induced pluripotent stem cells-derived MSCs facilitate cutaneous wound healing by promoting collagen synthesis and angiogenesis. J Transl Med (2015) 1.09

Microvesicles derived from human umbilical cord Wharton's jelly mesenchymal stem cells attenuate bladder tumor cell growth in vitro and in vivo. PLoS One (2013) 1.09

Systemic delivery of SapC-DOPS has antiangiogenic and antitumor effects against glioblastoma. Mol Ther (2013) 1.07

From microRNA functions to microRNA therapeutics: novel targets and novel drugs in breast cancer research and treatment (Review). Int J Oncol (2013) 1.06

Association of influenza virus proteins with membrane rafts. Adv Virol (2011) 1.04

Unraveling the Mystery of Cancer by Secretory microRNA: Horizontal microRNA Transfer between Living Cells. Front Genet (2012) 1.04

Do circulating tumor cells, exosomes, and circulating tumor nucleic acids have clinical utility? A report of the association for molecular pathology. J Mol Diagn (2015) 1.04

Exosomes/miRNAs as mediating cell-based therapy of stroke. Front Cell Neurosci (2014) 1.03

Mesenchymal Stem Cell-derived Extracellular Vesicles: Toward Cell-free Therapeutic Applications. Mol Ther (2015) 1.02

Extracellular vesicle transfer of cancer pathogenic components. Cancer Sci (2016) 1.01

Rho GTPases and their roles in cancer metabolism. Trends Mol Med (2012) 1.01

Microvesicles/exosomes as potential novel biomarkers of metabolic diseases. Diabetes Metab Syndr Obes (2012) 1.01

Regulation of the tumor suppressor PTEN through exosomes: a diagnostic potential for prostate cancer. PLoS One (2013) 1.01

Zoledronic acid inhibits macrophage/microglia-assisted breast cancer cell invasion. Oncotarget (2013) 1.01

Extracellular vesicles as emerging intercellular communicasomes. BMB Rep (2014) 1.00

Extracellular Vesicles: Satellites of Information Transfer in Cancer and Stem Cell Biology. Dev Cell (2016) 0.99

A hostel for the hostile: the bone marrow niche in hematologic neoplasms. Haematologica (2015) 0.99

Exosomes in Cancer Microenvironment and Beyond: have we Overlooked these Extracellular Messengers? Cancer Microenviron (2012) 0.99

Extracellular vesicles: communication, coercion, and conditioning. Mol Biol Cell (2013) 0.99

Paracrine effects of stem cells in wound healing and cancer progression (Review). Int J Oncol (2014) 0.99

MARCKS-ED peptide as a curvature and lipid sensor. ACS Chem Biol (2012) 0.97

Focus on Extracellular Vesicles: Introducing the Next Small Big Thing. Int J Mol Sci (2016) 0.96

Exploiting paracrine mechanisms of tissue regeneration to repair damaged organs. Transplant Res (2013) 0.96

Tumor and endothelial cell-derived microvesicles carry distinct CEACAMs and influence T-cell behavior. PLoS One (2013) 0.95

Mesenchymal Stem Cells: Rising Concerns over Their Application in Treatment of Type One Diabetes Mellitus. J Diabetes Res (2015) 0.95

Tumor-derived microvesicles induce proangiogenic phenotype in endothelial cells via endocytosis. PLoS One (2012) 0.94

Exosomes and Other Extracellular Vesicles: The New Communicators in Parasite Infections. Trends Parasitol (2015) 0.93

Insights into the key roles of proteoglycans in breast cancer biology and translational medicine. Biochim Biophys Acta (2015) 0.92

Induction and transport of Wnt 5a during macrophage-induced malignant invasion is mediated by two types of extracellular vesicles. Oncotarget (2013) 0.92

Exosome proteomics reveals transcriptional regulator proteins with potential to mediate downstream pathways. Cancer Sci (2014) 0.91

Cancer cells induced to express mesenchymal phenotype release exosome-like extracellular vesicles carrying tissue factor. J Biol Chem (2012) 0.91

Extracellular RNA mediates and marks cancer progression. Semin Cancer Biol (2014) 0.90

Post-prandial rise of microvesicles in peripheral blood of healthy human donors. Lipids Health Dis (2011) 0.89

The inflammatory tumor microenvironment, epithelial mesenchymal transition and lung carcinogenesis. Cancer Microenviron (2011) 0.89

Serum deprivation elevates the levels of microvesicles with different size distributions and selectively enriched proteins in human myeloma cells in vitro. Acta Pharmacol Sin (2013) 0.89

Extracellular vesicles as carriers of microRNA, proteins and lipids in tumor microenvironment. Int J Cancer (2015) 0.89

Cardiac Extracellular Vesicles in Normal and Infarcted Heart. Int J Mol Sci (2016) 0.88

Propofol exerts anti-hepatocellular carcinoma by microvesicle-mediated transfer of miR-142-3p from macrophage to cancer cells. J Transl Med (2014) 0.88

Stem cell-based delivery of Hypoxamir-210 to the infarcted heart: implications on stem cell survival and preservation of infarcted heart function. J Mol Med (Berl) (2012) 0.88

Microvescicles derived from mesenchymal stromal cells are not as effective as their cellular counterpart in the ability to modulate immune responses in vitro. Stem Cells Dev (2014) 0.88

Microfluidic isolation of cancer-cell-derived microvesicles from hetergeneous extracellular shed vesicle populations. Biomed Microdevices (2014) 0.88

ARF1 regulates the Rho/MLC pathway to control EGF-dependent breast cancer cell invasion. Mol Biol Cell (2013) 0.88

Wnt interaction and extracellular release of prominin-1/CD133 in human malignant melanoma cells. Exp Cell Res (2013) 0.87

Microparticles mediated cross-talk between tumoral and endothelial cells promote the constitution of a pro-metastatic vascular niche through Arf6 up regulation. Cancer Microenviron (2014) 0.87

Static magnetic field enhances synthesis and secretion of membrane-derived microvesicles (MVs) rich in VEGF and BMP-2 in equine adipose-derived stromal cells (EqASCs)-a new approach in veterinary regenerative medicine. In Vitro Cell Dev Biol Anim (2014) 0.87

A quantitative comparison of human HT-1080 fibrosarcoma cells and primary human dermal fibroblasts identifies a 3D migration mechanism with properties unique to the transformed phenotype. PLoS One (2013) 0.86

Cross Talk between Cancer and Mesenchymal Stem Cells through Extracellular Vesicles Carrying Nucleic Acids. Front Oncol (2016) 0.86

Enhanced shedding of extracellular vesicles from amoeboid prostate cancer cells: potential effects on the tumor microenvironment. Cancer Biol Ther (2014) 0.86

R(h)oads to microvesicles. Small GTPases (2012) 0.86

Non-apoptotic cell death associated with perturbations of macropinocytosis. Front Physiol (2015) 0.86

Role of Intracellular and Extracellular MicroRNA-92a in Colorectal Cancer. Transl Oncol (2013) 0.86

Exosomes released from breast cancer carcinomas stimulate cell movement. PLoS One (2015) 0.86

Tumor cell-expressed SerpinB2 is present on microparticles and inhibits metastasis. Cancer Med (2014) 0.85

Exosomes in prostate cancer: putting together the pieces of a puzzle. Cancers (Basel) (2013) 0.85

Detection of highly curved membrane surfaces using a cyclic peptide derived from synaptotagmin-I. ACS Chem Biol (2012) 0.85

Microvesicles provide a mechanism for intercellular communication by embryonic stem cells during embryo implantation. Nat Commun (2016) 0.85

Exosome-mediated Delivery of Hydrophobically Modified siRNA for Huntingtin mRNA Silencing. Mol Ther (2016) 0.85

Reversal of chemosensitivity and induction of cell malignancy of a non-malignant prostate cancer cell line upon extracellular vesicle exposure. Mol Cancer (2013) 0.84

Multiple myeloma dell-derived microvesicles are enriched in CD147 expression and enhance tumor cell proliferation. Oncotarget (2014) 0.84

Regulated delivery of molecular cargo to invasive tumour-derived microvesicles. Nat Commun (2015) 0.84

Cancerous epithelial cell lines shed extracellular vesicles with a bimodal size distribution that is sensitive to glutamine inhibition. Phys Biol (2014) 0.83

Ordering transitions triggered by specific binding of vesicles to protein-decorated interfaces of thermotropic liquid crystals. Langmuir (2012) 0.83

Hypoxic tumor-derived microvesicles negatively regulate NK cell function by a mechanism involving TGF-β and miR23a transfer. Oncoimmunology (2015) 0.83

Micrometric segregation of fluorescent membrane lipids: relevance for endogenous lipids and biogenesis in erythrocytes. J Lipid Res (2013) 0.83

Exosomes confer pro-survival signals to alter the phenotype of prostate cells in their surrounding environment. Oncotarget (2016) 0.82

Articles cited by this

(truncated to the top 100)

Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers. Nat Cell Biol (2008) 19.86

Angiogenesis in life, disease and medicine. Nature (2005) 15.36

MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer. Gynecol Oncol (2008) 11.46

Immunosuppressive networks in the tumour environment and their therapeutic relevance. Nat Rev Cancer (2005) 10.06

The immunobiology of cancer immunosurveillance and immunoediting. Immunity (2004) 9.39

Shedding microvesicles: artefacts no more. Trends Cell Biol (2009) 8.84

Apoptosis: controlled demolition at the cellular level. Nat Rev Mol Cell Biol (2008) 8.30

ARF proteins: roles in membrane traffic and beyond. Nat Rev Mol Cell Biol (2006) 7.75

Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells. Nat Cell Biol (2008) 7.30

Retrovirus budding. Annu Rev Cell Dev Biol (2004) 7.16

Exosomes--vesicular carriers for intercellular communication. Curr Opin Cell Biol (2009) 6.96

How proteins produce cellular membrane curvature. Nat Rev Mol Cell Biol (2006) 6.90

Membrane-derived microvesicles: important and underappreciated mediators of cell-to-cell communication. Leukemia (2006) 6.45

Embryonic stem cell-derived microvesicles reprogram hematopoietic progenitors: evidence for horizontal transfer of mRNA and protein delivery. Leukemia (2006) 6.31

Exosome function: from tumor immunology to pathogen biology. Traffic (2008) 4.50

Non-equilibration of hydrostatic pressure in blebbing cells. Nature (2005) 4.08

Tissue-factor-bearing microvesicles arise from lipid rafts and fuse with activated platelets to initiate coagulation. Blood (2005) 3.85

Multiple roles for Arf6: sorting, structuring, and signaling at the plasma membrane. J Biol Chem (2003) 3.53

Tumour-released exosomes and their implications in cancer immunity. Cell Death Differ (2007) 3.22

Tumour-derived microvesicles carry several surface determinants and mRNA of tumour cells and transfer some of these determinants to monocytes. Cancer Immunol Immunother (2005) 3.20

ATP-dependent asymmetric distribution of spin-labeled phospholipids in the erythrocyte membrane: relation to shape changes. Proc Natl Acad Sci U S A (1984) 3.13

Transfer of the chemokine receptor CCR5 between cells by membrane-derived microparticles: a mechanism for cellular human immunodeficiency virus 1 infection. Nat Med (2000) 3.10

Circulating microparticles: pathophysiology and clinical implications. Blood Rev (2006) 3.07

The human tumor cell-derived collagenase stimulatory factor (renamed EMMPRIN) is a member of the immunoglobulin superfamily. Cancer Res (1995) 3.04

Microparticle-associated tissue factor activity: a link between cancer and thrombosis? J Thromb Haemost (2006) 3.03

Induction of lymphocyte apoptosis by tumor cell secretion of FasL-bearing microvesicles. J Exp Med (2002) 3.02

Blood-borne tissue factor: another view of thrombosis. Proc Natl Acad Sci U S A (1999) 2.98

Fas ligand-positive membranous vesicles isolated from sera of patients with oral cancer induce apoptosis of activated T lymphocytes. Clin Cancer Res (2005) 2.97

ARF6-regulated shedding of tumor cell-derived plasma membrane microvesicles. Curr Biol (2009) 2.82

Tumor-released microvesicles as vehicles of immunosuppression. Cancer Res (2007) 2.80

A cancer cell metalloprotease triad regulates the basement membrane transmigration program. Genes Dev (2006) 2.78

Virus entry, assembly, budding, and membrane rafts. Microbiol Mol Biol Rev (2003) 2.68

Membrane microparticles: two sides of the coin. Physiology (Bethesda) (2005) 2.68

Endothelial expression of autocrine VEGF upon the uptake of tumor-derived microvesicles containing oncogenic EGFR. Proc Natl Acad Sci U S A (2009) 2.66

Human tumor-released microvesicles promote the differentiation of myeloid cells with transforming growth factor-beta-mediated suppressive activity on T lymphocytes. Cancer Res (2006) 2.61

Mechanisms of membrane deformation. Curr Opin Cell Biol (2003) 2.57

Exosomes biological significance: A concise review. Blood Cells Mol Dis (2006) 2.46

Cellular microparticles: a disseminated storage pool of bioactive vascular effectors. Curr Opin Hematol (2004) 2.42

Expression, activation, and function of integrin alphaMbeta2 (Mac-1) on neutrophil-derived microparticles. Blood (2008) 2.36

Unconventional secretory routes: direct protein export across the plasma membrane of mammalian cells. Traffic (2005) 2.34

Shedding of the matrix metalloproteinases MMP-2, MMP-9, and MT1-MMP as membrane vesicle-associated components by endothelial cells. Am J Pathol (2002) 2.27

MT1-MMP proinvasive activity is regulated by a novel Rab8-dependent exocytic pathway. EMBO J (2007) 2.16

Oncosome formation in prostate cancer: association with a region of frequent chromosomal deletion in metastatic disease. Cancer Res (2009) 2.07

Tumor-derived tissue factor-bearing microparticles are associated with venous thromboembolic events in malignancy. Clin Cancer Res (2009) 2.04

Prominin: a story of cholesterol, plasma membrane protrusions and human pathology. Traffic (2001) 2.03

Regulation of transbilayer plasma membrane phospholipid asymmetry. J Lipid Res (2002) 2.02

Human colorectal cancer cells induce T-cell death through release of proapoptotic microvesicles: role in immune escape. Gastroenterology (2005) 2.00

Bioavailability of VEGF in tumor-shed vesicles depends on vesicle burst induced by acidic pH. Neoplasia (2006) 1.98

Cortical actomyosin breakage triggers shape oscillations in cells and cell fragments. Biophys J (2005) 1.96

The amount and proteolytic content of vesicles shed by human cancer cell lines correlates with their in vitro invasiveness. Anticancer Res (1998) 1.94

Abnormal lysosomal trafficking and enhanced exosomal export of cisplatin in drug-resistant human ovarian carcinoma cells. Mol Cancer Ther (2005) 1.89

Vectorial budding of vesicles by asymmetrical enzymatic formation of ceramide in giant liposomes. Biophys J (2000) 1.74

Tumor-stroma interaction: positive feedback regulation of extracellular matrix metalloproteinase inducer (EMMPRIN) expression and matrix metalloproteinase-dependent generation of soluble EMMPRIN. Mol Cancer Res (2004) 1.73

Extracellular membrane vesicles from tumor cells promote angiogenesis via sphingomyelin. Cancer Res (2002) 1.73

The role of matrix vesicles in growth plate development and biomineralization. Front Biosci (2005) 1.70

Proinvasive properties of ovarian cancer ascites-derived membrane vesicles. Cancer Res (2004) 1.69

Implications of lipid microdomains for membrane curvature, budding and fission. Curr Opin Cell Biol (2001) 1.67

Arrest and metastasis of blood-borne tumor cells are modified by fusion of plasma membrane vesicles from highly metastatic cells. Proc Natl Acad Sci U S A (1980) 1.65

Lung cancer secreted microvesicles: underappreciated modulators of microenvironment in expanding tumors. Int J Cancer (2009) 1.64

The "seed and soil" hypothesis revisited. Lancet Oncol (2008) 1.60

Tumor-derived microvesicles modulate the establishment of metastatic melanoma in a phosphatidylserine-dependent manner. Cancer Lett (2009) 1.60

Expulsion of small molecules in vesicles shed by cancer cells: association with gene expression and chemosensitivity profiles. Cancer Res (2003) 1.59

Mononuclear cell tissue factor: cell of origin and requirements for activation. Blood (1979) 1.58

Transbilayer movement of fluorescent analogs of phosphatidylserine and phosphatidylethanolamine at the plasma membrane of cultured cells. Evidence for a protein-mediated and ATP-dependent process(es). J Biol Chem (1987) 1.56

MT1-MMP-dependent invasion is regulated by TI-VAMP/VAMP7. Curr Biol (2008) 1.55

Identification of a functional role for lipid asymmetry in biological membranes: Phosphatidylserine-skeletal protein interactions modulate membrane stability. Proc Natl Acad Sci U S A (2002) 1.53

Biological membranes as bilayer couples. III. Compensatory shape changes induced in membranes. J Cell Biol (1976) 1.52

The enterocyte microvillus is a vesicle-generating organelle. J Cell Biol (2009) 1.51

Characterisation and properties of ectosomes released by human polymorphonuclear neutrophils. Exp Cell Res (2003) 1.47

Matrix-degrading proteinases are shed in membrane vesicles by ovarian cancer cells in vivo and in vitro. Clin Exp Metastasis (1999) 1.46

ADP-ribosylation factor 6 regulates glioma cell invasion through the IQ-domain GTPase-activating protein 1-Rac1-mediated pathway. Cancer Res (2009) 1.40

Emission of membrane vesicles: roles in complement resistance, immunity and cancer. Springer Semin Immunopathol (2005) 1.39

ADP-ribosylation factor 6 regulates tumorigenic and invasive properties in vivo. Cancer Res (2009) 1.37

Polymorphonuclear neutrophil-derived ectosomes interfere with the maturation of monocyte-derived dendritic cells. J Immunol (2008) 1.37

Lipid topogenesis. J Lipid Res (1981) 1.36

Membrane microvesicles as actors in the establishment of a favorable prostatic tumoral niche: a role for activated fibroblasts and CX3CL1-CX3CR1 axis. Cancer Res (2009) 1.35

Selective localization of matrix metalloproteinase 9, beta1 integrins, and human lymphocyte antigen class I molecules on membrane vesicles shed by 8701-BC breast carcinoma cells. Cancer Res (1998) 1.33

Cell-derived microvesicles and cancer. Neth J Med (2009) 1.33

Procoagulant activity associated with plasma membrane vesicles shed by cultured tumor cells. Cancer Res (1983) 1.29

Isolation and identification of potential urinary microparticle biomarkers of bladder cancer. J Proteome Res (2008) 1.28

Generation of novel, secreted epidermal growth factor receptor (EGFR/ErbB1) isoforms via metalloprotease-dependent ectodomain shedding and exosome secretion. J Cell Biochem (2008) 1.27

Secretion of active membrane type 1 matrix metalloproteinase (MMP-14) into extracellular space in microvesicular exosomes. J Cell Biochem (2008) 1.26

Finishing the job: cytoskeletal and membrane events bring cytokinesis to an end. Exp Cell Res (2004) 1.23

Cathepsin B mediates the pH-dependent proinvasive activity of tumor-shed microvesicles. Neoplasia (2008) 1.19

Localization of the Epstein-Barr virus protein LMP 1 to exosomes. J Gen Virol (2003) 1.16

Cancer-associated thrombosis. Crit Rev Oncol Hematol (2007) 1.15

Statistical thermodynamics of membrane bending-mediated protein-protein attractions. Biophys J (2001) 1.14

Membrane vesicles in ovarian cancer fluids: a new potential marker. Anticancer Res (2000) 1.13

Selective outside-inside translocation of aminophospholipids in human platelets. Biochemistry (1987) 1.12

Differential mechanisms of microparticle transfer toB cells and monocytes: anti-inflammatory propertiesof microparticles. Eur J Immunol (2006) 1.11

Vesicle-associated urokinase plasminogen activator promotes invasion in prostate cancer cell lines. Clin Exp Metastasis (2000) 1.09

Platelet-derived microvesicles transfer tissue factor to monocytes but not to neutrophils. Platelets (2004) 1.04

Neurons produce FGF2 and VEGF and secrete them at least in part by shedding extracellular vesicles. J Cell Mol Med (2008) 1.02

Astrocytes shed extracellular vesicles that contain fibroblast growth factor-2 and vascular endothelial growth factor. Int J Mol Med (2008) 1.02

Observations on cell lines derived from a patient with Hodgkin's disease. Cancer Res (1978) 1.01

The role of tumor-and host-related tissue factor pools in oncogene-driven tumor progression. Thromb Res (2007) 0.95

Human monocytes both enhance and inhibit the growth of human pancreatic cancer in SCID mice. Anticancer Res (2008) 0.92

Shed membrane vesicles and clustering of membrane-bound proteolytic enzymes. Curr Top Dev Biol (2003) 0.88

Tissue factor storage, synthesis and function in normal and activated human platelets. Thromb Res (2008) 0.84

Intracellular regulation of the production and release of human erythroid-directed lymphokines. J Clin Invest (1991) 0.81

Articles by these authors

ARF6-regulated shedding of tumor cell-derived plasma membrane microvesicles. Curr Biol (2009) 2.82

ARF6-GTP recruits Nm23-H1 to facilitate dynamin-mediated endocytosis during adherens junctions disassembly. Nat Cell Biol (2002) 2.63

The interaction of IQGAP1 with the exocyst complex is required for tumor cell invasion downstream of Cdc42 and RhoA. J Cell Biol (2008) 2.39

Tumor-derived microvesicles: shedding light on novel microenvironment modulators and prospective cancer biomarkers. Genes Dev (2012) 2.22

Lysosomal targeting of E-cadherin: a unique mechanism for the down-regulation of cell-cell adhesion during epithelial to mesenchymal transitions. Mol Cell Biol (2005) 2.19

ADP-ribosylation factor 6 regulates tumor cell invasion through the activation of the MEK/ERK signaling pathway. Proc Natl Acad Sci U S A (2004) 1.71

Large oncosomes in human prostate cancer tissues and in the circulation of mice with metastatic disease. Am J Pathol (2012) 1.60

Endocytosis resumes during late mitosis and is required for cytokinesis. J Biol Chem (2005) 1.53

Localization and activation of the ARF6 GTPase during cleavage furrow ingression and cytokinesis. J Biol Chem (2002) 1.47

Modulation of Rac1 and ARF6 activation during epithelial cell scattering. J Biol Chem (2003) 1.44

ADP-ribosylation factor 6 regulates glioma cell invasion through the IQ-domain GTPase-activating protein 1-Rac1-mediated pathway. Cancer Res (2009) 1.40

ADP-ribosylation factor 6 regulates tumorigenic and invasive properties in vivo. Cancer Res (2009) 1.37

ARF6-mediated endocytic recycling impacts cell movement, cell division and lipid homeostasis. Semin Cell Dev Biol (2010) 1.30

Requirement of an intact microtubule cytoskeleton for aggregation and inclusion body formation by a mutant huntingtin fragment. Proc Natl Acad Sci U S A (2002) 1.24

Finishing the job: cytoskeletal and membrane events bring cytokinesis to an end. Exp Cell Res (2004) 1.23

ARF6-dependent activation of ERK and Rac1 modulates epithelial tubule development. EMBO J (2007) 1.11

The small GTPase ARF6 stimulates β-catenin transcriptional activity during WNT5A-mediated melanoma invasion and metastasis. Sci Signal (2013) 1.10

A requirement for ARF6 during the completion of cytokinesis. Exp Cell Res (2005) 1.07

Elevated phospholipase D activity in H-Ras- but not K-Ras-transformed cells by the synergistic action of RalA and ARF6. Mol Cell Biol (2003) 1.07

Arfaptin 2 regulates the aggregation of mutant huntingtin protein. Nat Cell Biol (2002) 0.93

Proteasome-mediated degradation of Rac1-GTP during epithelial cell scattering. Mol Biol Cell (2006) 0.93

Establishing epithelial glandular polarity: interlinked roles for ARF6, Rac1, and the matrix microenvironment. Mol Biol Cell (2012) 0.91

Investigating the role of ADP-ribosylation factor 6 in tumor cell invasion and extracellular signal-regulated kinase activation. Methods Enzymol (2005) 0.90

Unregulated ARF6 activation in epithelial cysts generates hyperactive signaling endosomes and disrupts morphogenesis. Mol Biol Cell (2010) 0.88

ARF6-mediated endosome recycling reverses lipid accumulation defects in Niemann-Pick Type C disease. PLoS One (2009) 0.86

Betacap73-ARF6 interactions modulate cell shape and motility after injury in vitro. Mol Biol Cell (2003) 0.84

Role for a Cindr-Arf6 axis in patterning emerging epithelia. Mol Biol Cell (2011) 0.84

Endocytic trafficking and Wnt/β-catenin signaling. Curr Drug Targets (2011) 0.81

ARF6-regulated endocytosis of growth factor receptors links cadherin-based adhesion to canonical Wnt signaling in epithelia. Mol Cell Biol (2013) 0.81

Modeling disease using three dimensional cell culture: multi-lumen and inverted cyst phenotypes. Front Biosci (Elite Ed) (2012) 0.75

Small GTPase signaling in cell physiology and disease. A preface. Curr Drug Targets (2011) 0.75

Arf6 modulates the beta-actin specific capping protein, betacap73. Methods Enzymol (2005) 0.75