S Matthijs Boekholdt

Author PubWeight™ 173.32‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Biological, clinical and population relevance of 95 loci for blood lipids. Nature 2010 28.21
2 Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet 2011 13.25
3 Triglycerides and the risk of coronary heart disease: 10,158 incident cases among 262,525 participants in 29 Western prospective studies. Circulation 2006 6.17
4 Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studies. Lancet 2010 5.31
5 Genetic variants influencing circulating lipid levels and risk of coronary artery disease. Arterioscler Thromb Vasc Biol 2010 4.08
6 HDL cholesterol and residual risk of first cardiovascular events after treatment with potent statin therapy: an analysis from the JUPITER trial. Lancet 2010 4.07
7 Lipid-related markers and cardiovascular disease prediction. JAMA 2012 3.91
8 Cardiovascular event reduction versus new-onset diabetes during atorvastatin therapy: effect of baseline risk factors for diabetes. J Am Coll Cardiol 2012 3.66
9 Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet 2012 3.21
10 Body fat distribution and risk of coronary heart disease in men and women in the European Prospective Investigation Into Cancer and Nutrition in Norfolk cohort: a population-based prospective study. Circulation 2007 3.20
11 Effect of torcetrapib on glucose, insulin, and hemoglobin A1c in subjects in the Investigation of Lipid Level Management to Understand its Impact in Atherosclerotic Events (ILLUMINATE) trial. Circulation 2011 3.01
12 High-density lipoprotein cholesterol, high-density lipoprotein particle size, and apolipoprotein A-I: significance for cardiovascular risk: the IDEAL and EPIC-Norfolk studies. J Am Coll Cardiol 2008 2.51
13 Beyond low-density lipoprotein cholesterol: respective contributions of non-high-density lipoprotein cholesterol levels, triglycerides, and the total cholesterol/high-density lipoprotein cholesterol ratio to coronary heart disease risk in apparently healthy men and women. J Am Coll Cardiol 2009 2.50
14 Evaluation of the Framingham risk score in the European Prospective Investigation of Cancer-Norfolk cohort: does adding glycated hemoglobin improve the prediction of coronary heart disease events? Arch Intern Med 2008 2.30
15 Lipids, apolipoproteins, and their ratios in relation to cardiovascular events with statin treatment. Circulation 2008 2.30
16 Value of low-density lipoprotein particle number and size as predictors of coronary artery disease in apparently healthy men and women: the EPIC-Norfolk Prospective Population Study. J Am Coll Cardiol 2007 2.29
17 Role of the apolipoprotein B-apolipoprotein A-I ratio in cardiovascular risk assessment: a case-control analysis in EPIC-Norfolk. Ann Intern Med 2007 2.26
18 Serum myeloperoxidase levels are associated with the future risk of coronary artery disease in apparently healthy individuals: the EPIC-Norfolk Prospective Population Study. J Am Coll Cardiol 2007 2.22
19 Secretory phospholipase A(2)-IIA and cardiovascular disease: a mendelian randomization study. J Am Coll Cardiol 2013 2.18
20 Hybrid myocardial perfusion SPECT/CT coronary angiography and invasive coronary angiography in patients with stable angina pectoris lead to similar treatment decisions. Heart 2012 2.05
21 Red cell distribution width is associated with physical inactivity and heart failure, independent of established risk factors, inflammation or iron metabolism; the EPIC-Norfolk study. Int J Cardiol 2013 2.05
22 High-density lipoprotein particle size and concentration and coronary risk. Ann Intern Med 2009 2.02
23 Family history of premature coronary heart disease and risk prediction in the EPIC-Norfolk prospective population study. Heart 2010 1.91
24 Determinants of residual risk in secondary prevention patients treated with high- versus low-dose statin therapy: the Treating to New Targets (TNT) study. Circulation 2012 1.76
25 Genetic variation at the phospholipid transfer protein locus affects its activity and high-density lipoprotein size and is a novel marker of cardiovascular disease susceptibility. Circulation 2010 1.75
26 Serum levels of mannose-binding lectin and the risk of future coronary artery disease in apparently healthy men and women. Arterioscler Thromb Vasc Biol 2006 1.62
27 The hypertriglyceridemic-waist phenotype and the risk of coronary artery disease: results from the EPIC-Norfolk prospective population study. CMAJ 2010 1.45
28 Lipid parameters for measuring risk of cardiovascular disease. Nat Rev Cardiol 2011 1.43
29 Clinical implications of JUPITER in a contemporary European population: the EPIC-Norfolk prospective population study. Eur Heart J 2013 1.41
30 C-reactive protein is a mediator of cardiovascular disease. Eur Heart J 2010 1.38
31 ANGPTL4 E40K and T266M: effects on plasma triglyceride and HDL levels, postprandial responses, and CHD risk. Arterioscler Thromb Vasc Biol 2008 1.34
32 The ACC/AHA 2013 guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular disease risk in adults: the good the bad and the uncertain: a comparison with ESC/EAS guidelines for the management of dyslipidaemias 2011. Eur Heart J 2014 1.34
33 Circulating secretory phospholipase A2 activity and risk of incident coronary events in healthy men and women: the EPIC-Norfolk study. Arterioscler Thromb Vasc Biol 2007 1.34
34 Oxidation-specific biomarkers, lipoprotein(a), and risk of fatal and nonfatal coronary events. J Am Coll Cardiol 2010 1.34
35 Inflammatory biomarkers, physical activity, waist circumference, and risk of future coronary heart disease in healthy men and women. Eur Heart J 2009 1.31
36 Inherited disorders of HDL metabolism and atherosclerosis. Curr Opin Lipidol 2005 1.29
37 Apolipoprotein A-V, triglycerides and risk of coronary artery disease: the prospective Epic-Norfolk Population Study. J Lipid Res 2006 1.28
38 Apolipoprotein A-II is inversely associated with risk of future coronary artery disease. Circulation 2007 1.23
39 HDL particle size and the risk of coronary heart disease in apparently healthy men and women: the EPIC-Norfolk prospective population study. Atherosclerosis 2009 1.21
40 Separating the mechanism-based and off-target actions of cholesteryl ester transfer protein inhibitors with CETP gene polymorphisms. Circulation 2009 1.20
41 PLA2G7 genotype, lipoprotein-associated phospholipase A2 activity, and coronary heart disease risk in 10 494 cases and 15 624 controls of European Ancestry. Circulation 2010 1.14
42 Ability of recombinant factor VIIa to reverse the anticoagulant effect of the pentasaccharide fondaparinux in healthy volunteers. Circulation 2002 1.13
43 The role of non-HDL cholesterol in risk stratification for coronary artery disease. Curr Atheroscler Rep 2012 1.11
44 On-treatment non-high-density lipoprotein cholesterol, apolipoprotein B, triglycerides, and lipid ratios in relation to residual vascular risk after treatment with potent statin therapy: JUPITER (justification for the use of statins in prevention: an intervention trial evaluating rosuvastatin). J Am Coll Cardiol 2012 1.11
45 Retinol-binding protein 4 and prediction of incident coronary events in healthy men and women. J Clin Endocrinol Metab 2008 1.10
46 Relationship of IgG and IgM autoantibodies and immune complexes to oxidized LDL with markers of oxidation and inflammation and cardiovascular events: results from the EPIC-Norfolk Study. J Lipid Res 2011 1.09
47 Serum lipoprotein lipase concentration and risk for future coronary artery disease: the EPIC-Norfolk prospective population study. Arterioscler Thromb Vasc Biol 2005 1.08
48 Gene polymorphisms and the risk of myocardial infarction--an emerging relation. N Engl J Med 2002 1.07
49 Lipoprotein(a) and risk of coronary, cerebrovascular, and peripheral artery disease: the EPIC-Norfolk prospective population study. Arterioscler Thromb Vasc Biol 2012 1.04
50 Cholesterol levels in small LDL particles predict the risk of coronary heart disease in the EPIC-Norfolk prospective population study. Eur Heart J 2007 1.04
51 Plasma levels of plant sterols and the risk of coronary artery disease: the prospective EPIC-Norfolk Population Study. J Lipid Res 2006 1.03
52 Retracted Plasma PCSK9 levels and clinical outcomes in the TNT (Treating to New Targets) trial: a nested case-control study. J Am Coll Cardiol 2012 1.01
53 The relationship between plasma angiopoietin-like protein 4 levels, angiopoietin-like protein 4 genotype, and coronary heart disease risk. Arterioscler Thromb Vasc Biol 2010 1.00
54 Osteoprotegerin and soluble receptor activator of nuclear factor-kappaB ligand and risk for coronary events: a nested case-control approach in the prospective EPIC-Norfolk population study 1993-2003. Arterioscler Thromb Vasc Biol 2009 0.97
55 Cholesteryl ester transfer protein (CETP) inhibition beyond raising high-density lipoprotein cholesterol levels: pathways by which modulation of CETP activity may alter atherogenesis. Arterioscler Thromb Vasc Biol 2006 0.94
56 Polymorphisms in APOA1 and LPL genes are statistically independently associated with fasting TG in men with CAD. Eur J Hum Genet 2005 0.93
57 Both paraoxonase-1 genotype and activity do not predict the risk of future coronary artery disease; the EPIC-Norfolk Prospective Population Study. PLoS One 2009 0.93
58 Physical activity, the Framingham risk score and risk of coronary heart disease in men and women of the EPIC-Norfolk study. Atherosclerosis 2009 0.92
59 Lack of association between common genetic variation in endothelial lipase (LIPG) and the risk for CAD and DVT. Atherosclerosis 2010 0.90
60 C-reactive protein, fatal and nonfatal coronary artery disease, stroke, and peripheral artery disease in the prospective EPIC-Norfolk cohort study. Arterioscler Thromb Vasc Biol 2013 0.89
61 Metabolic dyslipidemia and risk of future coronary heart disease in apparently healthy men and women: the EPIC-Norfolk prospective population study. Int J Cardiol 2009 0.87
62 Adiponectin and risk of coronary heart disease in apparently healthy men and women (from the EPIC-Norfolk Prospective Population Study). Am J Cardiol 2011 0.86
63 Physical activity, metabolic syndrome, and coronary risk: the EPIC-Norfolk prospective population study. Eur J Cardiovasc Prev Rehabil 2011 0.86
64 Genetic determinants of plasma HDL-cholesterol levels in familial hypercholesterolemia. Eur J Hum Genet 2005 0.86
65 Comparison between gradient gel electrophoresis and nuclear magnetic resonance spectroscopy in estimating coronary heart disease risk associated with LDL and HDL particle size. Clin Chem 2010 0.86
66 Lipid assessment, metabolic syndrome and coronary heart disease risk. Eur J Clin Invest 2010 0.85
67 Inhibition of lipoprotein-associated phospholipase activity by darapladib: shifting gears in cardiovascular drug development: are antiinflammatory drugs the next frontier? Circulation 2008 0.84
68 Non-HDL cholesterol vs. apo B for risk of coronary heart disease in healthy individuals: the EPIC-Norfolk prospective population study. Eur J Clin Invest 2013 0.84
69 The 719Arg variant of KIF6 and cardiovascular outcomes in statin-treated, stable coronary patients of the treating to new targets and incremental decrease in end points through aggressive lipid-lowering prospective studies. Circ Cardiovasc Genet 2011 0.84
70 Chemokine ligand 2 genetic variants, serum monocyte chemoattractant protein-1 levels, and the risk of coronary artery disease. Arterioscler Thromb Vasc Biol 2010 0.83
71 Major depression, C-reactive protein, and incident ischemic heart disease in healthy men and women. Psychosom Med 2008 0.83
72 Prolactin levels and the risk of future coronary artery disease in apparently healthy men and women. Circ Cardiovasc Genet 2009 0.82
73 Varespladib: targeting the inflammatory face of atherosclerosis. Eur Heart J 2010 0.80
74 Incremental diagnostic accuracy of hybrid SPECT/CT coronary angiography in a population with an intermediate to high pre-test likelihood of coronary artery disease. Eur Heart J Cardiovasc Imaging 2013 0.80
75 High-dose statin therapy in patients with stable coronary artery disease: treating the right patients based on individualized prediction of treatment effect. Circulation 2013 0.79
76 High-sensitivity troponin T is associated with poor outcome in adults with pulmonary arterial hypertension due to congenital heart disease. Congenit Heart Dis 2012 0.79
77 A comparative analysis of three widely used lipid management guidelines in the EPIC-Norfolk cohort. Eur J Prev Cardiol 2012 0.79
78 Relationship between atorvastatin dose and the harm caused by torcetrapib. J Lipid Res 2012 0.79
79 Validation of a model to investigate the effects of modifying cardiovascular disease (CVD) risk factors on the burden of CVD: the rotterdam ischemic heart disease and stroke computer simulation (RISC) model. BMC Med 2012 0.79
80 Thrombospondin gene polymorphisms and the risk of angiographic coronary in-stent restenosis. Am J Med 2004 0.78
81 Novel genetic approach to investigate the role of plasma secretory phospholipase A2 (sPLA2)-V isoenzyme in coronary heart disease: modified Mendelian randomization analysis using PLA2G5 expression levels. Circ Cardiovasc Genet 2014 0.78
82 Should we change our lipid management strategies to focus on non-high-density lipoprotein cholesterol? Curr Opin Cardiol 2010 0.78
83 Toll-like receptor 4 gene polymorphisms show no association with the risk of clinical or angiographic restenosis after percutaneous coronary intervention. Pharmacogenet Genomics 2010 0.78
84 Non-high-density lipoprotein cholesterol: current status as cardiovascular marker. Curr Opin Lipidol 2015 0.78
85 Usefulness of coronary calcium scoring to myocardial perfusion SPECT in the diagnosis of coronary artery disease in a predominantly high risk population. Int J Cardiovasc Imaging 2012 0.77
86 De-risking the clinical development of cholesteryl ester transfer protein inhibitors: how much is good enough? Eur Heart J 2011 0.76
87 Relationship between in vitro lipopolysaccharide-induced cytokine response in whole blood, angiographic in-stent restenosis, and toll-like receptor 4 gene polymorphisms. Clin Chem 2005 0.76
88 Response to letter by Balta et al. Int J Cardiol 2013 0.75
89 Prospective study of insulin-like growth factor-I, insulin-like growth factor-binding protein 3, genetic variants in the IGF1 and IGFBP3 genes and risk of coronary artery disease. Int J Mol Epidemiol Genet 2011 0.75
90 Reply: statin-induced low low-density lipoprotein cholesterol level: is lower better? J Am Coll Cardiol 2015 0.75
91 The authors’ reply. Heart 2013 0.75
92 Reply: To PMID 23219296. J Am Coll Cardiol 2013 0.75
93 Improving risk stratification for cardiovascular disease. Expert Rev Cardiovasc Ther 2010 0.75
94 Dilation of the Aorta Ascendens Forms Part of the Clinical Spectrum of HCN4 Mutations. J Am Coll Cardiol 2016 0.75
95 Clinical and biological relevance of statin-mediated changes in HDL metabolism. Curr Atheroscler Rep 2014 0.75
96 Lipoprotein(a) Improves Cardiovascular Risk Prediction Based on Established Risk Algorithms. J Am Coll Cardiol 2017 0.75
97 IgM antibodies against apoptotic cells and phosphorylcholine in patients with acute myocardial infarction in relation to infarct size and inflammatory response. Adv Clin Exp Med 2012 0.75
98 Coronary Artery Disease Affects Symptomatology of Aortic Valve Stenosis. J Am Coll Cardiol 2017 0.75
99 Rates and determinants of progressive aortic valve dysfunction in aortic coarctation. Int J Cardiol 2012 0.75
100 Impact of abdominal obesity and systemic hypertension on risk of coronary heart disease in men and women: the EPIC-Norfolk Population Study. J Hypertens 2014 0.75