Published in J Hepatol on April 21, 2010
Interleukin-22 treatment ameliorates alcoholic liver injury in a murine model of chronic-binge ethanol feeding: role of signal transducer and activator of transcription 3. Hepatology (2010) 2.40
Interleukin-22 alleviates metabolic disorders and restores mucosal immunity in diabetes. Nature (2014) 2.08
Signal transducer and activator of transcription 3 in liver diseases: a novel therapeutic target. Int J Biol Sci (2011) 1.70
In vivo consequences of liver-specific interleukin-22 expression in mice: Implications for human liver disease progression. Hepatology (2011) 1.69
Hepatoprotective and anti-inflammatory cytokines in alcoholic liver disease. J Gastroenterol Hepatol (2012) 1.49
STAT proteins - key regulators of anti-viral responses, inflammation, and tumorigenesis in the liver. J Hepatol (2012) 1.15
Biologically active, high levels of interleukin-22 inhibit hepatic gluconeogenesis but do not affect obesity and its metabolic consequences. Cell Biosci (2015) 1.15
Fat: a matter of disturbance for the immune system. World J Gastroenterol (2010) 1.13
Pathogenesis of alcoholic liver disease: role of oxidative metabolism. World J Gastroenterol (2014) 1.06
Dietary whey protein lowers the risk for metabolic disease in mice fed a high-fat diet. J Nutr (2011) 1.04
Cytokines and STATs in Liver Fibrosis. Front Physiol (2012) 1.02
Interleukin-22: implications for liver ischemia-reperfusion injury. Transplantation (2012) 1.02
IL-22 in tissue-protective therapy. Br J Pharmacol (2013) 0.98
Fibrosis Related Inflammatory Mediators: Role of the IL-10 Cytokine Family. Mediators Inflamm (2015) 0.96
Hepatoprotective and anti-fibrotic functions of interleukin-22: therapeutic potential for the treatment of alcoholic liver disease. J Gastroenterol Hepatol (2013) 0.94
High fat diet induces formation of spontaneous liposarcoma in mouse adipose tissue with overexpression of interleukin 22. PLoS One (2011) 0.93
IL-22: An Evolutionary Missing-Link Authenticating the Role of the Immune System in Tissue Regeneration. J Cancer (2012) 0.91
Interleukins in chronic liver disease: lessons learned from experimental mouse models. Clin Exp Gastroenterol (2014) 0.85
Melatonin attenuates acute pancreatitis-associated lung injury in rats by modulating interleukin 22. World J Gastroenterol (2012) 0.85
Amelioration of liver injury by continuously targeted intervention against TNFRp55 in rats with acute-on-chronic liver failure. PLoS One (2013) 0.84
Interleukin-22 ameliorates liver fibrogenesis by attenuating hepatic stellate cell activation and downregulating the levels of inflammatory cytokines. World J Gastroenterol (2015) 0.83
Role of interleukin-22 in liver diseases. Inflamm Res (2014) 0.81
Hepatic deletion of Smad7 in mouse leads to spontaneous liver dysfunction and aggravates alcoholic liver injury. PLoS One (2011) 0.80
Deciphering the role of interleukin-22 in metabolic alterations. Cell Biosci (2015) 0.77
Highest frequencies of interleukin-22-producing T helper cells in alcoholic hepatitis patients with a favourable short-term course. PLoS One (2013) 0.77
Mechanisms of interleukin-22's beneficial effects in acute pancreatitis. World J Gastrointest Pathophysiol (2016) 0.76
Cyclin Y Is Involved in the Regulation of Adipogenesis and Lipid Production. PLoS One (2015) 0.76
Antioxidant axis Nrf2-keap1-ARE in inhibition of alcoholic liver fibrosis by IL-22. World J Gastroenterol (2017) 0.75
Therapy with interleukin-22 alleviates hepatic injury and hemostasis dysregulation in rat model of acute liver failure. Adv Hematol (2014) 0.75
Interleukin-22 ameliorates acute severe pancreatitis-associated lung injury in mice. World J Gastroenterol (2016) 0.75
How Does Interleukin-22 Mediate Liver Regeneration and Prevent Injury and Fibrosis? J Immunol Res (2016) 0.75
Gelidium elegans Regulates the AMPK-PRDM16-UCP-1 Pathway and Has a Synergistic Effect with Orlistat on Obesity-Associated Features in Mice Fed a High-Fat Diet. Nutrients (2017) 0.75
Research advances at the Institute for Nutritional Sciences at Shanghai, China. Adv Nutr (2011) 0.75
Is intestinal inflammation linking dysbiosis to gut barrier dysfunction during liver disease? Expert Rev Gastroenterol Hepatol (2015) 0.75
Alcoholic hepatitis: The pivotal role of Kupffer cells. World J Gastrointest Pathophysiol (2015) 0.75
Retinoic Acid Regulates Immune Responses by Promoting IL-22 and Modulating S100 Proteins in Viral Hepatitis. J Immunol (2017) 0.75
Interleukin-22 contributes to liver regeneration in mice with concanavalin A-induced hepatitis after hepatectomy. World J Gastroenterol (2016) 0.75
Praziquantel treatment after Schistosoma japonicum infection maintains hepatic insulin sensitivity and improves glucose metabolism in mice. Parasit Vectors (2017) 0.75
AR-V7 and resistance to enzalutamide and abiraterone in prostate cancer. N Engl J Med (2014) 12.29
Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle. J Biol Chem (2002) 9.76
A syndrome of altered cardiovascular, craniofacial, neurocognitive and skeletal development caused by mutations in TGFBR1 or TGFBR2. Nat Genet (2005) 9.62
Single-cell exome sequencing and monoclonal evolution of a JAK2-negative myeloproliferative neoplasm. Cell (2012) 5.16
Hepatitis C virus production by human hepatocytes dependent on assembly and secretion of very low-density lipoproteins. Proc Natl Acad Sci U S A (2007) 4.05
Latent transforming growth factor beta-binding protein 1 interacts with fibrillin and is a microfibril-associated protein. J Biol Chem (2002) 3.92
Structural methodologies for auditing SNOMED. J Biomed Inform (2006) 3.46
H7N9 influenza viruses are transmissible in ferrets by respiratory droplet. Science (2013) 3.33
A nuclear function of beta-arrestin1 in GPCR signaling: regulation of histone acetylation and gene transcription. Cell (2005) 3.22
Plasma 25-hydroxyvitamin D concentration and metabolic syndrome among middle-aged and elderly Chinese individuals. Diabetes Care (2009) 3.20
Single-vector inducible lentiviral RNAi system for oncology target validation. Cell Cycle (2009) 3.14
Domain mapping studies reveal that the M domain of hsp90 serves as a molecular scaffold to regulate Akt-dependent phosphorylation of endothelial nitric oxide synthase and NO release. Circ Res (2002) 3.01
Integrin alphaVbeta6-mediated activation of latent TGF-beta requires the latent TGF-beta binding protein-1. J Cell Biol (2004) 2.90
Melamine related bilateral renal calculi in 50 children: single center experience in clinical diagnosis and treatment. J Urol (2010) 2.83
Auditing as part of the terminology design life cycle. J Am Med Inform Assoc (2006) 2.73
Interactions between gut microbiota, host genetics and diet relevant to development of metabolic syndromes in mice. ISME J (2009) 2.69
A Smac mimetic rescue screen reveals roles for inhibitor of apoptosis proteins in tumor necrosis factor-alpha signaling. Cancer Res (2007) 2.52
Prenatal airborne polycyclic aromatic hydrocarbon exposure and child IQ at age 5 years. Pediatrics (2009) 2.43
Syphilis treatment response among HIV-discordant couples in Zambia and Rwanda. Clin Infect Dis (2013) 2.22
Analysis of error concentrations in SNOMED. AMIA Annu Symp Proc (2007) 2.18
A microfluidic processor for gene expression profiling of single human embryonic stem cells. Lab Chip (2007) 2.17
IQGAP1 is a scaffold for mitogen-activated protein kinase signaling. Mol Cell Biol (2005) 2.16
The Jasmonate-ZIM-domain proteins interact with the WD-Repeat/bHLH/MYB complexes to regulate Jasmonate-mediated anthocyanin accumulation and trichome initiation in Arabidopsis thaliana. Plant Cell (2011) 2.11
Supplementation of fat grafts with adipose-derived regenerative cells improves long-term graft retention. Ann Plast Surg (2010) 2.06
Cellular characterization of adenylate kinase and its isoform: two-photon excitation fluorescence imaging and fluorescence correlation spectroscopy. Biophys J (2002) 1.99
IQGAP1 binds ERK2 and modulates its activity. J Biol Chem (2004) 1.99
TGF-beta induces proangiogenic and antiangiogenic factors via parallel but distinct Smad pathways. Kidney Int (2004) 1.95
Overexpression of uncoupling protein 3 in skeletal muscle protects against fat-induced insulin resistance. J Clin Invest (2007) 1.91
Pharmacokinetics, oral bioavailability, and metabolic profile of resveratrol and its dimethylether analog, pterostilbene, in rats. Cancer Chemother Pharmacol (2010) 1.85
GSK3-TIP60-ULK1 signaling pathway links growth factor deprivation to autophagy. Science (2012) 1.84
Modifiable risk factors and major cardiac events among adult survivors of childhood cancer. J Clin Oncol (2013) 1.83
Etiology and clinical characteristics of membranous nephropathy in Chinese patients. Am J Kidney Dis (2008) 1.80
Endothelial-specific expression of caveolin-1 impairs microvascular permeability and angiogenesis. Proc Natl Acad Sci U S A (2004) 1.75
The orphan nuclear receptor Nur77 regulates LKB1 localization and activates AMPK. Nat Chem Biol (2012) 1.75
Molecular assembly of an aptamer-drug conjugate for targeted drug delivery to tumor cells. Chembiochem (2009) 1.73
EGFR tyrosine kinase inhibitors activate autophagy as a cytoprotective response in human lung cancer cells. PLoS One (2011) 1.73
IQGAP1 promotes cell motility and invasion. J Biol Chem (2003) 1.72
Age-related retinopathy in NRF2-deficient mice. PLoS One (2011) 1.71
Atrial natriuretic peptide promotes cardiomyocyte survival by cGMP-dependent nuclear accumulation of zyxin and Akt. J Clin Invest (2005) 1.70
Endostar, a novel recombinant human endostatin, exerts antiangiogenic effect via blocking VEGF-induced tyrosine phosphorylation of KDR/Flk-1 of endothelial cells. Biochem Biophys Res Commun (2007) 1.69
Identifying quantitative trait loci via group-sparse multitask regression and feature selection: an imaging genetics study of the ADNI cohort. Bioinformatics (2011) 1.69
Cardiovascular risk factors in adult survivors of pediatric cancer--a report from the childhood cancer survivor study. Cancer Epidemiol Biomarkers Prev (2010) 1.61
Fibronectin is required for integrin alphavbeta6-mediated activation of latent TGF-beta complexes containing LTBP-1. FASEB J (2005) 1.61
Transcatheter arterial chemoembolization in combination with radiotherapy for unresectable hepatocellular carcinoma: a systematic review and meta-analysis. Radiother Oncol (2008) 1.57
IQGAP1 modulates activation of B-Raf. Proc Natl Acad Sci U S A (2007) 1.57
Genome-wide association study identifies NRG1 as a susceptibility locus for Hirschsprung's disease. Proc Natl Acad Sci U S A (2009) 1.56
Novel proteolytic microvesicles released from human macrophages after exposure to tobacco smoke. Am J Pathol (2013) 1.54
Identifying AD-sensitive and cognition-relevant imaging biomarkers via joint classification and regression. Med Image Comput Comput Assist Interv (2011) 1.54
Maternal mosaicism is a significant contributor to discordant sex chromosomal aneuploidies associated with noninvasive prenatal testing. Clin Chem (2013) 1.54
A crucial role for RACK1 in the regulation of glucose-stimulated IRE1alpha activation in pancreatic beta cells. Sci Signal (2010) 1.52
A marker of endotoxemia is associated with obesity and related metabolic disorders in apparently healthy Chinese. Diabetes Care (2010) 1.52
Assessment of four DNA fragments (COI, 16S rDNA, ITS2, 12S rDNA) for species identification of the Ixodida (Acari: Ixodida). Parasit Vectors (2014) 1.51
Anti-fatigue activity of the water-soluble polysaccharides isolated from Panax ginseng C. A. Meyer. J Ethnopharmacol (2010) 1.51
Survivors of childhood cancer have increased risk of gastrointestinal complications later in life. Gastroenterology (2011) 1.51
Dephosphorylation of the nuclear factor of activated T cells (NFAT) transcription factor is regulated by an RNA-protein scaffold complex. Proc Natl Acad Sci U S A (2011) 1.47
IQGAP1 stimulates proliferation and enhances tumorigenesis of human breast epithelial cells. J Biol Chem (2007) 1.46
Functional reconstitution of endothelial nitric oxide synthase reveals the importance of serine 1179 in endothelium-dependent vasomotion. Circ Res (2002) 1.46
Cytological analysis and genetic control of rice anther development. J Genet Genomics (2011) 1.45
Prenatal exposure to airborne polycyclic aromatic hydrocarbons and children's intelligence at 5 years of age in a prospective cohort study in Poland. Environ Health Perspect (2010) 1.44
Carbon nanotube-quenched fluorescent oligonucleotides: probes that fluoresce upon hybridization. J Am Chem Soc (2008) 1.43
Determination of arsenic metabolites in patients with newly diagnosed acute promyelocytic leukemia treated with arsenic trioxide. Leuk Lymphoma (2013) 1.42
Effect of a robotic prescription-filling system on pharmacy staff activities and prescription-filling time. Am J Health Syst Pharm (2007) 1.41
Perturbation of transforming growth factor (TGF)-beta1 association with latent TGF-beta binding protein yields inflammation and tumors. Proc Natl Acad Sci U S A (2008) 1.40
Up-regulation of Cathepsin G in the Development of Chronic Postsurgical Pain: An Experimental and Clinical Genetic Study. Anesthesiology (2015) 1.39
IQGAP1 is a component of Cdc42 signaling to the cytoskeleton. J Biol Chem (2002) 1.39
Upregulation of circulating PD-L1/PD-1 is associated with poor post-cryoablation prognosis in patients with HBV-related hepatocellular carcinoma. PLoS One (2011) 1.38
Arsenite causes DNA damage in keratinocytes via generation of hydroxyl radicals. Chem Res Toxicol (2004) 1.37
Bone abnormalities in latent TGF-[beta] binding protein (Ltbp)-3-null mice indicate a role for Ltbp-3 in modulating TGF-[beta] bioavailability. J Cell Biol (2002) 1.37
Epidemiological characteristics and genetic structure of blaNDM-1 in non-baumannii Acinetobacter spp. in China. J Antimicrob Chemother (2012) 1.36
IQGAP1-mediated stimulation of transcriptional co-activation by beta-catenin is modulated by calmodulin. J Biol Chem (2001) 1.36
Large-scale cDNA transfection screening for genes related to cancer development and progression. Proc Natl Acad Sci U S A (2004) 1.35
Neonatal bilirubin levels and childhood asthma in the US Collaborative Perinatal Project, 1959-1965. Am J Epidemiol (2013) 1.34
Genomes of the rice pest brown planthopper and its endosymbionts reveal complex complementary contributions for host adaptation. Genome Biol (2014) 1.34
Fluorescence correlation spectroscopy. Methods Enzymol (2003) 1.33
A universal method for the preparation of covalent protein-DNA conjugates for use in creating protein nanostructures. Angew Chem Int Ed Engl (2007) 1.33
Assembly of aptamer switch probes and photosensitizer on gold nanorods for targeted photothermal and photodynamic cancer therapy. ACS Nano (2012) 1.32
A highly specific BODIPY-based fluorescent probe for the detection of hypochlorous acid. Org Lett (2008) 1.32
In utero arsenic exposure and infant infection in a United States cohort: a prospective study. Environ Res (2013) 1.31
MicroRNA-449 and microRNA-34b/c function redundantly in murine testes by targeting E2F transcription factor-retinoblastoma protein (E2F-pRb) pathway. J Biol Chem (2012) 1.31
Genomic insights into salt adaptation in a desert poplar. Nat Commun (2013) 1.30
The Salmonella SPI2 effector SseI mediates long-term systemic infection by modulating host cell migration. PLoS Pathog (2009) 1.30
Identifying disease sensitive and quantitative trait-relevant biomarkers from multidimensional heterogeneous imaging genetics data via sparse multimodal multitask learning. Bioinformatics (2012) 1.30
Spatial regulation of Raf kinase signaling by RKTG. Proc Natl Acad Sci U S A (2007) 1.29
Auditing complex concepts of SNOMED using a refined hierarchical abstraction network. J Biomed Inform (2011) 1.29
Essential roles of the PI3 kinase/Akt pathway in regulating Nrf2-dependent antioxidant functions in the RPE. Invest Ophthalmol Vis Sci (2008) 1.28
miR-223 regulates migration and invasion by targeting Artemin in human esophageal carcinoma. J Biomed Sci (2011) 1.27
Extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase pathway is involved in myostatin-regulated differentiation repression. Cancer Res (2006) 1.26
Antioxidant activity of sulfated polysaccharide fractions extracted from Undaria pinnitafida in vitro. Int J Biol Macromol (2009) 1.26
Dual-color photon counting histogram analysis of mRFP1 and EGFP in living cells. Biophys J (2006) 1.25
Antagonists to human and mouse vascular endothelial growth factor receptor 2 generated by directed protein evolution in vitro. Chem Biol (2006) 1.24
Hand-held arthroscopic optical coherence tomography for in vivo high-resolution imaging of articular cartilage. J Biomed Opt (2003) 1.24
Long form of latent TGF-beta binding protein 1 (Ltbp1L) is essential for cardiac outflow tract septation and remodeling. Development (2007) 1.22
Whole-genome sequencing of Oryza brachyantha reveals mechanisms underlying Oryza genome evolution. Nat Commun (2013) 1.22
The membrane-bound transcription factor CREB3L1 is activated in response to virus infection to inhibit proliferation of virus-infected cells. Cell Host Microbe (2011) 1.22
Draft genome sequence of the Tibetan antelope. Nat Commun (2013) 1.22
Autophagy inhibition enhances daunorubicin-induced apoptosis in K562 cells. PLoS One (2011) 1.22
High-frequency canonical Wnt activation in multiple sarcoma subtypes drives proliferation through a TCF/β-catenin target gene, CDC25A. Cancer Cell (2011) 1.22
Constitutive expression of a miR319 gene alters plant development and enhances salt and drought tolerance in transgenic creeping bentgrass. Plant Physiol (2013) 1.21