Published in J Neurochem on August 19, 2010
Emerging role of DYRK family protein kinases as regulators of protein stability in cell cycle control. Cell Cycle (2012) 1.05
Protease regulation: the Yin and Yang of neural development and disease. Neuron (2011) 1.00
Regulation of RCAN1 protein activity by Dyrk1A protein-mediated phosphorylation. J Biol Chem (2011) 0.94
Recent advances in the design, synthesis, and biological evaluation of selective DYRK1A inhibitors: a new avenue for a disease modifying treatment of Alzheimer's? ACS Chem Neurosci (2012) 0.91
A chemical with proven clinical safety rescues Down-syndrome-related phenotypes in through DYRK1A inhibition. Dis Model Mech (2016) 0.82
Truncation and Activation of Dual Specificity Tyrosine Phosphorylation-regulated Kinase 1A by Calpain I: A MOLECULAR MECHANISM LINKED TO TAU PATHOLOGY IN ALZHEIMER DISEASE. J Biol Chem (2015) 0.82
Bioactive marine drugs and marine biomaterials for brain diseases. Mar Drugs (2014) 0.81
Structural features underlying the selectivity of the kinase inhibitors NBC and dNBC: role of a nitro group that discriminates between CK2 and DYRK1A. Cell Mol Life Sci (2011) 0.81
DYRK1A, a Dosage-Sensitive Gene Involved in Neurodevelopmental Disorders, Is a Target for Drug Development in Down Syndrome. Front Behav Neurosci (2016) 0.79
Dissecting Alzheimer disease in Down syndrome using mouse models. Front Behav Neurosci (2015) 0.79
Phosphorylation and inactivation of glycogen synthase kinase 3β (GSK3β) by dual-specificity tyrosine phosphorylation-regulated kinase 1A (Dyrk1A). J Biol Chem (2014) 0.78
10-iodo-11H-indolo[3,2-c]quinoline-6-carboxylic acids are selective inhibitors of DYRK1A. J Med Chem (2015) 0.78
Current pharmacotherapy and putative disease-modifying therapy for Alzheimer's disease. Neurol Sci (2016) 0.77
An ELISA DYRK1A non-radioactive kinase assay suitable for the characterization of inhibitors. F1000Res (2017) 0.75
Pathogenic PS1 phosphorylation at Ser367. Elife (2017) 0.75
One-carbon cycle alterations induced by Dyrk1a dosage. Mol Genet Metab Rep (2014) 0.75
COP1 and ELF3 control circadian function and photoperiodic flowering by regulating GI stability. Mol Cell (2008) 2.34
Endoscopic diagnosis of open-type atrophic gastritis is related to the histological diagnosis of intestinal metaplasia and Cdx2 expression. Dig Dis Sci (2011) 1.93
A human breast cell model of preinvasive to invasive transition. Cancer Res (2008) 1.79
DYRK1A BAC transgenic mice show altered synaptic plasticity with learning and memory defects. Neurobiol Dis (2006) 1.74
Vesicle-associated membrane protein 3 (VAMP-3) and VAMP-8 are present in human platelets and are required for granule secretion. Blood (2002) 1.67
Cell shape regulates global histone acetylation in human mammary epithelial cells. Exp Cell Res (2007) 1.64
Comparing the outcomes of radiofrequency ablation and surgery in patients with a single small hepatocellular carcinoma and well-preserved hepatic function. J Clin Gastroenterol (2005) 1.57
DYRK1A-mediated hyperphosphorylation of Tau. A functional link between Down syndrome and Alzheimer disease. J Biol Chem (2007) 1.54
Serum cytokines and critical illness-related corticosteroid insufficiency. Intensive Care Med (2010) 1.51
Clinical characteristics and the expression profiles of inflammatory cytokines/cytokine regulatory factors in asymptomatic patients with nodular gastritis. Dig Dis Sci (2012) 1.49
Function and regulation of Dyrk1A: towards understanding Down syndrome. Cell Mol Life Sci (2009) 1.44
Capsaicin induces apoptosis of cisplatin-resistant stomach cancer cells by causing degradation of cisplatin-inducible Aurora-A protein. Nutr Cancer (2011) 1.44
Gastric cancers with microsatellite instability exhibit high fluorodeoxyglucose uptake on positron emission tomography. Gastric Cancer (2012) 1.44
Risk for coronary heart disease increases risk for colorectal neoplasm. Clin Gastroenterol Hepatol (2012) 1.43
Serum amyloid A stimulates matrix-metalloproteinase-9 upregulation via formyl peptide receptor like-1-mediated signaling in human monocytic cells. Biochem Biophys Res Commun (2005) 1.40
Fucoidan present in brown algae induces apoptosis of human colon cancer cells. BMC Gastroenterol (2010) 1.37
A bioinformatics analysis of memory consolidation reveals involvement of the transcription factor c-rel. J Neurosci (2004) 1.37
The Effect of the Bowel Preparation Status on the Risk of Missing Polyp and Adenoma during Screening Colonoscopy: A Tandem Colonoscopic Study. Clin Endosc (2012) 1.32
Endoscopic mucosal resection and endoscopic submucosal dissection as treatments for early gastrointestinal cancers in Western countries. Gut Liver (2007) 1.32
Dual-specificity tyrosine(Y)-phosphorylation regulated kinase 1A-mediated phosphorylation of amyloid precursor protein: evidence for a functional link between Down syndrome and Alzheimer's disease. J Neurochem (2007) 1.29
Cyst formation in kidney via B-Raf signaling in the PKD2 transgenic mice. J Biol Chem (2008) 1.24
Empathic exchanges in online cancer support groups: distinguishing message expression and reception effects. Health Commun (2011) 1.22
Tumor suppressor ras association domain family 5 (RASSF5/NORE1) mediates death receptor ligand-induced apoptosis. J Biol Chem (2010) 1.20
Minibrain/Dyrk1a regulates food intake through the Sir2-FOXO-sNPF/NPY pathway in Drosophila and mammals. PLoS Genet (2012) 1.20
Wnt-7a causes loss of differentiated phenotype and inhibits apoptosis of articular chondrocytes via different mechanisms. J Biol Chem (2004) 1.20
Microbial community and metabolomic comparison of irritable bowel syndrome faeces. J Med Microbiol (2011) 1.19
Cytomegalovirus colitis in immunocompetent patients: a clinical and endoscopic study. Hepatogastroenterology (2012) 1.18
Cyclic AMP response element-binding protein overexpression: a feature associated with negative prognosis in never smokers with non-small cell lung cancer. Cancer Res (2008) 1.18
Delta-catenin-induced dendritic morphogenesis. An essential role of p190RhoGEF interaction through Akt1-mediated phosphorylation. J Biol Chem (2007) 1.18
DNA hypermethylation near the transcription start site of collagen alpha2(I) gene occurs in both cancer cell lines and primary colorectal cancers. Cancer Res (2003) 1.16
Phosphorylation of SNAP-23 in activated human platelets. J Biol Chem (2003) 1.15
Comparison of tiotropium plus fluticasone propionate/salmeterol with tiotropium in COPD: a randomized controlled study. Respir Med (2011) 1.14
S1P stimulates chemotactic migration and invasion in OVCAR3 ovarian cancer cells. Biochem Biophys Res Commun (2007) 1.13
Micropropagation of Phalaenopsis orchids via protocorms and protocorm-like bodies. Methods Mol Biol (2011) 1.12
Depressive mood and quality of life in functional gastrointestinal disorders: differences between functional dyspepsia, irritable bowel syndrome and overlap syndrome. Gen Hosp Psychiatry (2010) 1.09
Effects of Pro12Ala polymorphism of peroxisome proliferator-activated receptor gamma2 gene on rosiglitazone response in type 2 diabetes. Clin Pharmacol Ther (2005) 1.09
The influence of adiponectin gene polymorphism on the rosiglitazone response in patients with type 2 diabetes. Diabetes Care (2005) 1.06
Transitional CpG methylation between promoters and retroelements of tissue-specific genes during human mesenchymal cell differentiation. J Cell Biochem (2007) 1.06
alpha-Synuclein exhibits competitive interaction between calmodulin and synthetic membranes. J Neurochem (2002) 1.06
Regulation of Notch1/NICD and Hes1 expressions by GSK-3alpha/beta. Mol Cells (2008) 1.05
Reversal of serologic, immunologic, and histologic dysfunction in mice with systemic lupus erythematosus by long-term serial adipose tissue-derived mesenchymal stem cell transplantation. Arthritis Rheum (2012) 1.05
Transplantation of CTLA4Ig gene-transduced adipose tissue-derived mesenchymal stem cells reduces inflammatory immune response and improves Th1/Th2 balance in experimental autoimmune thyroiditis. J Gene Med (2011) 1.03
Higher circulating sphingosine 1-phosphate levels are associated with lower bone mineral density and higher bone resorption marker in humans. J Clin Endocrinol Metab (2012) 1.03
Dyrk1A phosphorylates p53 and inhibits proliferation of embryonic neuronal cells. J Biol Chem (2010) 1.02
Prospective, randomized, back-to-back trial evaluating the usefulness of i-SCAN in screening colonoscopy. Gastrointest Endosc (2012) 1.01
Evaluation of consumer-style cooking methods for reduction of Escherichia coli O157:H7 in ground beef. J Food Prot (2003) 1.01
AMP kinase acts as a negative regulator of RANKL in the differentiation of osteoclasts. Bone (2010) 1.00
BMP-2-enhanced chondrogenesis involves p38 MAPK-mediated down-regulation of Wnt-7a pathway. Mol Cells (2006) 1.00
High FDG uptake in PET/CT predicts worse prognosis in patients with metastatic gastric adenocarcinoma. J Cancer Res Clin Oncol (2010) 1.00
delta-Catenin promotes prostate cancer cell growth and progression by altering cell cycle and survival gene profiles. Mol Cancer (2009) 0.99
Lidocaine sprayed down the endotracheal tube attenuates the airway-circulatory reflexes by local anesthesia during emergence and extubation. Anesth Analg (2003) 0.99
Health surveillance study of workers who manufacture multi-walled carbon nanotubes. Nanotoxicology (2014) 0.99
Activation of caspase-8 contributes to 3,3'-Diindolylmethane-induced apoptosis in colon cancer cells. J Nutr (2007) 0.99
Helicobacter pylori infection increases the risk of colorectal adenomas: cross-sectional study and meta-analysis. Dig Dis Sci (2012) 0.99
WNK4 phosphorylates ser(206) of claudin-7 and promotes paracellular Cl(-) permeability. FEBS Lett (2007) 0.97
Circulating vitamin D and colorectal adenoma in asymptomatic average-risk individuals who underwent first screening colonoscopy: a case-control study. Dig Dis Sci (2011) 0.97
Hypercalcemia in hepatic tuberculosis: a case report in Korea. Am J Trop Med Hyg (2005) 0.97
Lysophosphatidylserine stimulates L2071 mouse fibroblast chemotactic migration via a process involving pertussis toxin-sensitive trimeric G-proteins. Mol Pharmacol (2005) 0.95
Delta-catenin/NPRAP: A new member of the glycogen synthase kinase-3beta signaling complex that promotes beta-catenin turnover in neurons. J Neurosci Res (2010) 0.95
Presenilin-1 inhibits delta-catenin-induced cellular branching and promotes delta-catenin processing and turnover. Biochem Biophys Res Commun (2006) 0.94
Lysophosphatidylethanolamine stimulates chemotactic migration and cellular invasion in SK-OV3 human ovarian cancer cells: involvement of pertussis toxin-sensitive G-protein coupled receptor. FEBS Lett (2007) 0.94
Clinical outcomes for patients with perforations during endoscopic submucosal dissection of laterally spreading tumors of the colorectum. Surg Endosc (2012) 0.94
Regulation of RCAN1 protein activity by Dyrk1A protein-mediated phosphorylation. J Biol Chem (2011) 0.94
Intramuscular diffuse-type tenosynovial giant cell tumor of the deltoid muscle in a child. Skeletal Radiol (2014) 0.93
Arabidopsis MKK4 mediates osmotic-stress response via its regulation of MPK3 activity. Biochem Biophys Res Commun (2011) 0.93
All-solid-state flexible supercapacitors fabricated with bacterial nanocellulose papers, carbon nanotubes, and triblock-copolymer ion gels. ACS Nano (2012) 0.93
3,3'-Diindolylmethane inhibits prostate cancer development in the transgenic adenocarcinoma mouse prostate model. Mol Carcinog (2010) 0.93
Serum amyloid A induces contrary immune responses via formyl peptide receptor-like 1 in human monocytes. Mol Pharmacol (2006) 0.93
GSK-3 phosphorylates delta-catenin and negatively regulates its stability via ubiquitination/proteosome-mediated proteolysis. J Biol Chem (2009) 0.93
Outcomes in critically ill patients with hematologic malignancies who received renal replacement therapy for acute kidney injury in an intensive care unit. J Crit Care (2010) 0.93
Effects of exercise and diet change on cognition function and synaptic plasticity in high fat diet induced obese rats. Lipids Health Dis (2013) 0.92
Anti-inflammatory and anti-allergic effects of kefir in a mouse asthma model. Immunobiology (2007) 0.92
The Neuregulin-Rac-MKK7 pathway regulates antagonistic c-jun/Krox20 expression in Schwann cell dedifferentiation. Glia (2013) 0.92
The grape component piceatannol induces apoptosis in DU145 human prostate cancer cells via the activation of extrinsic and intrinsic pathways. J Med Food (2009) 0.91
The gene expression profiling in murine cortical cells undergoing programmed cell death (PCD) induced by serum deprivation. J Biochem Mol Biol (2007) 0.91
δ-Catenin promotes E-cadherin processing and activates β-catenin-mediated signaling: implications on human prostate cancer progression. Biochim Biophys Acta (2012) 0.91
AtERF71/HRE2 transcription factor mediates osmotic stress response as well as hypoxia response in Arabidopsis. Biochem Biophys Res Commun (2011) 0.91
The spectrum of vascularized superficial soft-tissue tumors on sonography with a histopathologic correlation: Part 2, malignant tumors and their look-alikes. AJR Am J Roentgenol (2010) 0.90
Antimicrobial effects of mustard flour and acetic acid against Escherichia coli O157:H7, Listeria monocytogenes, and Salmonella enterica serovar Typhimurium. Appl Environ Microbiol (2003) 0.90
Validation of the Simplified Acute Physiology Score 3 scoring system in a Korean intensive care unit. Yonsei Med J (2011) 0.90
High frequency of microsatellite instability in intestinal-type gastric cancer in Korean patients. Korean J Intern Med (2005) 0.90
Early Gastric Cancer-Like Advanced Gastric Cancer versus Advanced Gastric Cancer-Like Early Gastric Cancer. Clin Endosc (2013) 0.90
A novel collagen-binding peptide promotes osteogenic differentiation via Ca2+/calmodulin-dependent protein kinase II/ERK/AP-1 signaling pathway in human bone marrow-derived mesenchymal stem cells. Cell Signal (2007) 0.89
TGF-beta3 inhibits chondrogenesis of cultured chick leg bud mesenchymal cells via downregulation of connexin 43 and integrin beta4. J Cell Physiol (2008) 0.89
Negative feedback Inhibition of NFATc1 by DYRK1A regulates bone homeostasis. J Biol Chem (2009) 0.89