Published in Adv Immunol on December 01, 2009
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Immunology of age-related macular degeneration. Nat Rev Immunol (2013) 2.14
Complement System Part I - Molecular Mechanisms of Activation and Regulation. Front Immunol (2015) 1.52
Collectin-11 detects stress-induced L-fucose pattern to trigger renal epithelial injury. J Clin Invest (2016) 1.43
Overview of complement activation and regulation. Semin Nephrol (2013) 1.26
Recent insights into C3 glomerulopathy. Nephrol Dial Transplant (2013) 1.21
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The role of the immune response in age-related macular degeneration. Int J Inflam (2013) 1.16
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Genetic variants in the complement system predisposing to age-related macular degeneration: a review. Mol Immunol (2014) 1.04
The complotype: dictating risk for inflammation and infection. Trends Immunol (2012) 1.03
Properdin in complement activation and tissue injury. Mol Immunol (2013) 0.95
Rare genetic variants in the CFI gene are associated with advanced age-related macular degeneration and commonly result in reduced serum factor I levels. Hum Mol Genet (2015) 0.95
Therapeutic control of complement activation at the level of the central component C3. Immunobiology (2015) 0.94
The role of complement in membranous nephropathy. Semin Nephrol (2013) 0.90
Factor H binds to the hypervariable region of many Streptococcus pyogenes M proteins but does not promote phagocytosis resistance or acute virulence. PLoS Pathog (2013) 0.90
Complotype affects the extent of down-regulation by Factor I of the C3b feedback cycle in vitro. Clin Exp Immunol (2015) 0.90
Low-dose recombinant properdin provides substantial protection against Streptococcus pneumoniae and Neisseria meningitidis infection. Proc Natl Acad Sci U S A (2014) 0.89
The alternative pathway of complement activation may be involved in the renal damage of human anti-glomerular basement membrane disease. PLoS One (2014) 0.87
Identification of a novel mode of complement activation on stimulated platelets mediated by properdin and C3(H2O). J Immunol (2013) 0.87
Solution structure of CCP modules 10-12 illuminates functional architecture of the complement regulator, factor H. J Mol Biol (2012) 0.86
Use of time-resolved FRET to validate crystal structure of complement regulatory complex between C3b and factor H (N terminus). Protein Sci (2011) 0.84
Estimation of interdomain flexibility of N-terminus of factor H using residual dipolar couplings. Biochemistry (2011) 0.83
Functional analyses of complement convertases using C3 and C5-depleted sera. PLoS One (2012) 0.82
Review: Complement and its regulatory proteins in kidney diseases. Nephrology (Carlton) (2010) 0.82
Complement Evasion Mediated by Enhancement of Captured Factor H: Implications for Protection of Self-Surfaces from Complement. J Immunol (2015) 0.80
Functional Characterization of Autoantibodies against Complement Component C3 in Patients with Lupus Nephritis. J Biol Chem (2015) 0.79
Complement-Coagulation Cross-Talk: A Potential Mediator of the Physiological Activation of Complement by Low pH. Front Immunol (2015) 0.79
Glomerular C1q deposition and serum anti-C1q antibodies in anti-glomerular basement membrane disease. BMC Immunol (2013) 0.78
Selectivity of C3-opsonin targeted complement inhibitors: A distinct advantage in the protection of erythrocytes from paroxysmal nocturnal hemoglobinuria patients. Immunobiology (2016) 0.78
Retracted Properdin homeostasis requires turnover of the alternative complement pathway. Proc Natl Acad Sci U S A (2010) 0.78
Rare Variants in the Functional Domains of Complement Factor H Are Associated With Age-Related Macular Degeneration. Invest Ophthalmol Vis Sci (2015) 0.78
Mannan binding lectin-associated serine protease-2 (MASP-2) critically contributes to post-ischemic brain injury independent of MASP-1. J Neuroinflammation (2016) 0.77
Complementopathies. Blood Rev (2017) 0.76
Properdin binding to complement activating surfaces depends on initial C3b deposition. Proc Natl Acad Sci U S A (2017) 0.76
Targeting mechanisms at sites of complement activation for imaging and therapy. Immunobiology (2015) 0.76
Evolution of the complement system: from defense of the single cell to guardian of the intravascular space. Immunol Rev (2016) 0.75
A Novel Complotype Combination Associates with Age-Related Macular Degeneration and High Complement Activation Levels in vivo. Sci Rep (2016) 0.75
Incidence and profile of C3 Glomerulopathy: A single center study. Indian J Nephrol (2015) 0.75
Disease-linked mutations in factor H reveal pivotal role of cofactor activity in self surface-selective regulation of complement activation. J Biol Chem (2017) 0.75
THE PATHOPHYSIOLOGY OF GEOGRAPHIC ATROPHY SECONDARY TO AGE-RELATED MACULAR DEGENERATION AND THE COMPLEMENT PATHWAY AS A THERAPEUTIC TARGET. Retina (2016) 0.75
Complement-Mediated Regulation of Apolipoprotein E in Cultured Human RPE Cells. Invest Ophthalmol Vis Sci (2017) 0.75
The Evolving Landscape for Complement Therapeutics in Rheumatic and Autoimmune Diseases. Arthritis Rheumatol (2017) 0.75
Inhibition of complement C5 protects against organ failure and reduces mortality in a baboon model of Escherichia coli sepsis. Proc Natl Acad Sci U S A (2017) 0.75
Activation of complement factor B contributes to murine and human myocardial ischemia/reperfusion injury. PLoS One (2017) 0.75