Published in Proc Natl Acad Sci U S A on May 10, 2010
Galactosylated fucose epitopes in nematodes: increased expression in a Caenorhabditis mutant associated with altered lectin sensitivity and occurrence in parasitic species. J Biol Chem (2012) 0.99
The role of protein N-glycosylation in neural transmission. Glycobiology (2014) 0.95
Biosynthetic Machinery Involved in Aberrant Glycosylation: Promising Targets for Developing of Drugs Against Cancer. Front Oncol (2015) 0.91
Mgat1-dependent N-glycosylation of membrane components primes Drosophila melanogaster blood cells for the cellular encapsulation response. PLoS Pathog (2012) 0.87
Neural-specific α3-fucosylation of N-linked glycans in the Drosophila embryo requires fucosyltransferase A and influences developmental signaling associated with O-glycosylation. Glycobiology (2010) 0.86
N-glycosylation in regulation of the nervous system. Adv Neurobiol (2014) 0.83
Structure-function analysis of endogenous lectin mind-the-gap in synaptogenesis. Dev Neurobiol (2012) 0.83
Modeling absolute differences in life expectancy with a censored skew-normal regression approach. PeerJ (2015) 0.82
N-glycosylation requirements in neuromuscular synaptogenesis. Development (2013) 0.82
Classical galactosaemia: novel insights in IgG N-glycosylation and N-glycan biosynthesis. Eur J Hum Genet (2016) 0.80
Life is sweet! A novel role for N-glycans in Drosophila lifespan. Fly (Austin) (2011) 0.79
Deficiency of α-glucosidase I alters glycoprotein glycosylation and lifespan in Caenorhabditis elegans. Glycobiology (2013) 0.78
The N's and O's of Drosophila glycoprotein glycobiology. Glycoconj J (2012) 0.76
Comprehensive Glycomics of a Multistep Human Brain Tumor Model Reveals Specific Glycosylation Patterns Related to Malignancy. PLoS One (2015) 0.75
Protein N-glycosylation and N-glycan trimming are required for postembryonic development of the pest beetle Tribolium castaneum. Sci Rep (2016) 0.75
Chromosomal microarray analysis in clinical evaluation of neurodevelopmental disorders-reporting a novel deletion of SETDB1 and illustration of counseling challenge. Pediatr Res (2016) 0.75
Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development (1993) 58.26
Sir2 mediates longevity in the fly through a pathway related to calorie restriction. Proc Natl Acad Sci U S A (2004) 9.25
The endocrine regulation of aging by insulin-like signals. Science (2003) 8.10
Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein. Science (2001) 7.85
Drosophila dFOXO controls lifespan and regulates insulin signalling in brain and fat body. Nature (2004) 6.38
Extended life-span and stress resistance in the Drosophila mutant methuselah. Science (1998) 6.22
Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurons. Nat Genet (1998) 5.55
A conditional tissue-specific transgene expression system using inducible GAL4. Proc Natl Acad Sci U S A (2001) 4.93
Complex N-glycan number and degree of branching cooperate to regulate cell proliferation and differentiation. Cell (2007) 4.85
Long-lived Drosophila with overexpressed dFOXO in adult fat body. Science (2004) 4.70
Extended life-span conferred by cotransporter gene mutations in Drosophila. Science (2000) 4.62
Making a better RNAi vector for Drosophila: use of intron spacers. Methods (2003) 4.42
Regulation of cytokine receptors by Golgi N-glycan processing and endocytosis. Science (2004) 3.73
Genetic defects in the human glycome. Nat Rev Genet (2006) 3.59
P[Switch], a system for spatial and temporal control of gene expression in Drosophila melanogaster. Proc Natl Acad Sci U S A (2001) 2.92
Drosophila lifespan control by dietary restriction independent of insulin-like signaling. Aging Cell (2008) 2.41
Metabolism, cell surface organization, and disease. Cell (2009) 2.41
Mice lacking N-acetylglucosaminyltransferase I activity die at mid-gestation, revealing an essential role for complex or hybrid N-linked carbohydrates. Proc Natl Acad Sci U S A (1994) 2.21
Complex asparagine-linked oligosaccharides are required for morphogenic events during post-implantation development. EMBO J (1994) 1.97
The GAL4 system as a tool for unravelling the mysteries of the Drosophila nervous system. Curr Opin Neurobiol (1995) 1.59
Alteration of Drosophila life span using conditional, tissue-specific expression of transgenes triggered by doxycyline or RU486/Mifepristone. Exp Gerontol (2007) 1.51
Adaptive regulation at the cell surface by N-glycosylation. Traffic (2009) 1.50
The 'yellow brick road' to branched complex N-glycans. Glycobiology (1991) 1.46
The joys of HexNAc. The synthesis and function of N- and O-glycan branches. Glycoconj J (2001) 1.23
JNK/FOXO-mediated neuronal expression of fly homologue of peroxiredoxin II reduces oxidative stress and extends life span. J Biol Chem (2009) 1.21
Null mutations in Drosophila N-acetylglucosaminyltransferase I produce defects in locomotion and a reduced life span. J Biol Chem (2006) 1.14
Revealing the anti-HRP epitope in Drosophila and Caenorhabditis. Glycoconj J (2008) 1.09
Delayed behavioural aging and altered mortality in Drosophila beta integrin mutants. Aging Cell (2003) 0.98
Control of oxidative stress resistance by IP3 kinase in Drosophila melanogaster. Free Radic Biol Med (2002) 0.94
N-glycans are involved in the response of Caenorhabditis elegans to bacterial pathogens. Methods Enzymol (2006) 0.91
Cloning and expression of Drosophila melanogaster UDP-GlcNAc:alpha-3-D-mannoside beta1,2-N-acetylglucosaminyltransferase I. Biol Chem (2001) 0.90
Sexual differences for emigration behavior in natural populations of Drosophila melanogaster. Behav Genet (2002) 0.86
Cytokine sensitivity and N-glycan processing mutations. Methods Enzymol (2006) 0.77
LARGE can functionally bypass alpha-dystroglycan glycosylation defects in distinct congenital muscular dystrophies. Nat Med (2004) 3.00
O-mannosyl phosphorylation of alpha-dystroglycan is required for laminin binding. Science (2010) 2.98
ISPD loss-of-function mutations disrupt dystroglycan O-mannosylation and cause Walker-Warburg syndrome. Nat Genet (2012) 1.93
Walker-Warburg syndrome. Orphanet J Rare Dis (2006) 1.59
Syntaxin 5 is required for cytokinesis and spermatid differentiation in Drosophila. Dev Biol (2002) 1.37
Mice with a homozygous deletion of the Mgat2 gene encoding UDP-N-acetylglucosamine:alpha-6-D-mannoside beta1,2-N-acetylglucosaminyltransferase II: a model for congenital disorder of glycosylation type IIa. Biochim Biophys Acta (2002) 1.20
Inhibition of the sodium/potassium ATPase impairs N-glycan expression and function. Cancer Res (2008) 1.17
Null mutations in Drosophila N-acetylglucosaminyltransferase I produce defects in locomotion and a reduced life span. J Biol Chem (2006) 1.14
Cloning and expression of a novel UDP-GlcNAc:alpha-D-mannoside beta1,2-N-acetylglucosaminyltransferase homologous to UDP-GlcNAc:alpha-3-D-mannoside beta1,2-N-acetylglucosaminyltransferase I. Biochem J (2002) 1.10
Mild POMGnT1 mutations underlie a novel limb-girdle muscular dystrophy variant. Arch Neurol (2008) 1.05
Great expectations for PIP: phosphoinositides as regulators of signaling during development and disease. Dev Cell (2009) 1.00
Regulation of Commissureless by the ubiquitin ligase DNedd4 is required for neuromuscular synaptogenesis in Drosophila melanogaster. Mol Cell Biol (2006) 0.97
Caenorhabditis elegans triple null mutant lacking UDP-N-acetyl-D-glucosamine:alpha-3-D-mannoside beta1,2-N-acetylglucosaminyltransferase I. Biochem J (2004) 0.97
AP-1 and clathrin are essential for secretory granule biogenesis in Drosophila. Mol Biol Cell (2011) 0.96
Drosophila syntaxin 16 is a Q-SNARE implicated in Golgi dynamics. J Cell Sci (2002) 0.95
Neuroligin 2 is required for synapse development and function at the Drosophila neuromuscular junction. J Neurosci (2011) 0.95
big bang gene modulates gut immune tolerance in Drosophila. Proc Natl Acad Sci U S A (2013) 0.95
Dominant-negative NSF2 disrupts the structure and function of Drosophila neuromuscular synapses. J Neurobiol (2002) 0.92
Neurexins and neuroligins: recent insights from invertebrates. Mol Neurobiol (2011) 0.92
N-glycans are involved in the response of Caenorhabditis elegans to bacterial pathogens. Methods Enzymol (2006) 0.91
The NHR1 domain of Neuralized binds Delta and mediates Delta trafficking and Notch signaling. Mol Biol Cell (2006) 0.91
nemy encodes a cytochrome b561 that is required for Drosophila learning and memory. Proc Natl Acad Sci U S A (2008) 0.91
Age-related behavioral changes in Drosophila. Ann N Y Acad Sci (2010) 0.90
Neuralized contains a phosphoinositide-binding motif required downstream of ubiquitination for delta endocytosis and notch signaling. Dev Cell (2007) 0.89
Membrane trafficking in cytokinesis. Semin Cell Dev Biol (2002) 0.89
Peptide-induced modulation of synaptic transmission and escape response in Drosophila requires two G-protein-coupled receptors. J Neurosci (2010) 0.89
The presenilin-2 loop peptide perturbs intracellular Ca2+ homeostasis and accelerates apoptosis. J Biol Chem (2006) 0.89
The metabolism of histamine in the Drosophila optic lobe involves an ommatidial pathway: β-alanine recycles through the retina. J Exp Biol (2012) 0.88
Identifying genes that interact with Drosophila presenilin and amyloid precursor protein. Genesis (2009) 0.87
Presynaptic plasticity and associative learning are impaired in a Drosophila presenilin null mutant. Dev Neurobiol (2007) 0.87
Healthy aging - insights from Drosophila. Front Physiol (2012) 0.86
Characterization of a gamma-adaptin ear-binding motif in enthoprotin. FEBS Lett (2003) 0.86
The PCome of Caenorhabditis elegans as a prototypic model system for parasitic nematodes: identification of phosphorylcholine-substituted proteins. Mol Biochem Parasitol (2008) 0.86
Characterization of big bang, a novel gene encoding for PDZ domain-containing proteins that are dynamically expressed throughout Drosophila development. Gene Expr Patterns (2006) 0.85
Modeling obesity and its associated disorders in Drosophila. Physiology (Bethesda) (2013) 0.85
The BAR domain of amphiphysin is required for cleavage furrow tip-tubule formation during cellularization in Drosophila embryos. Mol Biol Cell (2013) 0.84
Drosophila as a model to study age-related neurodegenerative disorders: Alzheimer's disease. Exp Gerontol (2010) 0.84
Regulation of Drosophila life-span: effect of genetic background, sex, mating and social status. Exp Gerontol (2009) 0.83
A method for proteomic identification of membrane-bound proteins containing Asn-linked oligosaccharides. Anal Biochem (2004) 0.83
Enzymatic diagnostic test for Muscle-Eye-Brain type congenital muscular dystrophy using commercially available reagents. Clin Biochem (2003) 0.83
Carriers and patients with muscle-eye-brain disease can be rapidly diagnosed by enzymatic analysis of fibroblasts and lymphoblasts. Neuromuscul Disord (2006) 0.83
UDP-N-acetylglucosamine:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I and UDP-N-acetylglucosamine:alpha-6-D-mannoside beta-1,2-N-acetylglucosaminyltransferase II in Caenorhabditis elegans. Biochim Biophys Acta (2002) 0.82
Equilibrative nucleoside transporter 2 regulates associative learning and synaptic function in Drosophila. J Neurosci (2010) 0.82
Novel memory mutants in Drosophila: behavioral characteristics of the mutant nemyP153. BMC Neurosci (2002) 0.81
Suppression of cancer progression by MGAT1 shRNA knockdown. PLoS One (2012) 0.81
Walker-Warburg Syndrome with POMT1 mutations can be associated with cleft lip and cleft palate. Neuromuscul Disord (2008) 0.81
Identification of the hydrophobic glycoproteins of Caenorhabditis elegans. Glycobiology (2005) 0.80
Modeling age-related diseases in Drosophila: can this fly? Curr Top Dev Biol (2005) 0.80
Intracellular calcium deficits in Drosophila cholinergic neurons expressing wild type or FAD-mutant presenilin. PLoS One (2009) 0.80
FKBP14 is an essential gene that regulates Presenilin protein levels and Notch signaling in Drosophila. Development (2013) 0.80
Sloppy paired 1/2 regulate glial cell fates by inhibiting Gcm function. Glia (2007) 0.79
A splice isoform of DNedd4, DNedd4-long, negatively regulates neuromuscular synaptogenesis and viability in Drosophila. PLoS One (2011) 0.79
Liquid facets-related (lqfR) is required for egg chamber morphogenesis during Drosophila oogenesis. PLoS One (2011) 0.79
Isolation of null alleles of the Caenorhabditis elegans gly-12, gly-13 and gly-14 genes, all of which encode UDP-GlcNAc: alpha-3-D-mannoside beta1,2-N-acetylglucosaminyltransferase I activity. Biochimie (2003) 0.79
Two closely related forms of UDP-GlcNAc: alpha6-D-mannoside beta1,2-N-acetylglucosaminyltransferase II occur in the clawed frog Xenopus laevis. Glycoconj J (2002) 0.79
Novel strategies for the development of animal models of refractory epilepsy. Adv Neurol (2006) 0.78
Gene inactivation confirms the identity of enzymes involved in nematode phosphorylcholine-N-glycan synthesis. Mol Biochem Parasitol (2007) 0.77
The neuralized homology repeat 1 domain of Drosophila neuralized mediates nuclear envelope association and delta-dependent inhibition of nuclear import. J Mol Biol (2007) 0.77
Functional analysis of the NHR2 domain indicates that oligomerization of Neuralized regulates ubiquitination and endocytosis of Delta during Notch signaling. Mol Cell Biol (2012) 0.75
Robert Gunter Spiro. Glycobiology (2015) 0.75
Robert Spiro Obituary. Glycoconj J (2015) 0.75
Scientific progress and the common good: the dilemma of recombinant DNA. Leg Med Q (1977) 0.75