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1
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MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts.
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Nature
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2008
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10.73
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2
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MicroRNAs in the human heart: a clue to fetal gene reprogramming in heart failure.
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Circulation
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2007
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6.41
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3
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What is the role of beta-adrenergic signaling in heart failure?
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Circ Res
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2003
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3.22
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4
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Cyclic AMP imaging in adult cardiac myocytes reveals far-reaching beta1-adrenergic but locally confined beta2-adrenergic receptor-mediated signaling.
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Circ Res
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2006
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2.66
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5
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Phytophthora infestans effector AVR3a is essential for virulence and manipulates plant immunity by stabilizing host E3 ligase CMPG1.
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Proc Natl Acad Sci U S A
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2010
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2.07
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6
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A phenotypic screen to identify hypertrophy-modulating microRNAs in primary cardiomyocytes.
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J Mol Cell Cardiol
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2011
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2.07
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7
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Analysis of receptor oligomerization by FRAP microscopy.
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Nat Methods
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2009
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2.06
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8
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Cardiac fibroblast-derived microRNA passenger strand-enriched exosomes mediate cardiomyocyte hypertrophy.
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J Clin Invest
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2014
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2.06
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9
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The transcriptional repressor Nab1 is a specific regulator of pathological cardiac hypertrophy.
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Nat Med
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2005
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2.02
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10
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MicroRNA-24 regulates vascularity after myocardial infarction.
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Circulation
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2011
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1.98
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11
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NPP1, a Phytophthora-associated trigger of plant defense in parsley and Arabidopsis.
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Plant J
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2002
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1.93
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12
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Critical role for stromal interaction molecule 1 in cardiac hypertrophy.
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Circulation
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2011
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1.91
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13
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Phytotoxicity and innate immune responses induced by Nep1-like proteins.
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Plant Cell
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2006
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1.88
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14
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The miRNA-212/132 family regulates both cardiac hypertrophy and cardiomyocyte autophagy.
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Nat Commun
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2012
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1.88
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15
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Gs activation is time-limiting in initiating receptor-mediated signaling.
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J Biol Chem
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2006
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1.52
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16
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Real-time optical recording of beta1-adrenergic receptor activation reveals supersensitivity of the Arg389 variant to carvedilol.
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J Clin Invest
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2007
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1.44
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17
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MiR-378 controls cardiac hypertrophy by combined repression of mitogen-activated protein kinase pathway factors.
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Circulation
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2013
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1.42
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18
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Real-time monitoring of the PDE2 activity of live cells: hormone-stimulated cAMP hydrolysis is faster than hormone-stimulated cAMP synthesis.
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J Biol Chem
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2004
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1.30
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19
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Inhibition of p38 alpha MAPK rescues cardiomyopathy induced by overexpressed beta 2-adrenergic receptor, but not beta 1-adrenergic receptor.
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J Clin Invest
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2007
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1.17
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20
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GPCR and G proteins: drug efficacy and activation in live cells.
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Mol Endocrinol
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2009
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1.16
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21
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A role for caspase-1 in heart failure.
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Circ Res
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2007
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1.13
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22
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Comparison of different miR-21 inhibitor chemistries in a cardiac disease model.
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J Clin Invest
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2011
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1.10
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23
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Common genomic response in different mouse models of beta-adrenergic-induced cardiomyopathy.
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Circulation
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2003
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1.10
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24
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Disruption of cardiac Ena-VASP protein localization in intercalated disks causes dilated cardiomyopathy.
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Am J Physiol Heart Circ Physiol
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2003
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1.04
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25
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A secretion trap screen in yeast identifies protease inhibitor 16 as a novel antihypertrophic protein secreted from the heart.
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Circulation
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2007
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1.03
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26
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Disrupting the EMMPRIN (CD147)-cyclophilin A interaction reduces infarct size and preserves systolic function after myocardial ischemia and reperfusion.
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Arterioscler Thromb Vasc Biol
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2011
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1.02
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27
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Pharmacases.de - a student-centered e-learning project of clinical pharmacology.
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Med Teach
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2013
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0.97
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28
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Interstitial remodeling in beta1-adrenergic receptor transgenic mice.
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Basic Res Cardiol
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2006
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0.97
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29
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Inhibition of nuclear import of calcineurin prevents myocardial hypertrophy.
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Circ Res
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2006
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0.96
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30
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microRNA-22 promotes heart failure through coordinate suppression of PPAR/ERR-nuclear hormone receptor transcription.
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PLoS One
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2013
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0.96
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31
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Ca2+-dependent lipid binding and membrane integration of PopA, a harpin-like elicitor of the hypersensitive response in tobacco.
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Mol Microbiol
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2005
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0.94
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32
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Regulation of cAMP homeostasis by the efflux protein MRP4 in cardiac myocytes.
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FASEB J
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2011
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0.94
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33
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Pulmonary hypertension and right heart failure in pituitary adenylate cyclase-activating polypeptide type I receptor-deficient mice.
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Circulation
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2004
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0.93
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34
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Activation of AP-1 contributes to the beta-adrenoceptor-mediated myocardial induction of interleukin-6.
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Mol Med
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2007
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0.93
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35
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Partial agonist activity of bucindolol is dependent on the activation state of the human beta1-adrenergic receptor.
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Circulation
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2003
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0.92
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36
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The bispecific SDF1-GPVI fusion protein preserves myocardial function after transient ischemia in mice.
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Circulation
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2012
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0.92
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37
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A polymorphism-specific "memory" mechanism in the β(2)-adrenergic receptor.
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Sci Signal
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2011
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0.88
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38
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Cardiac myocyte-secreted cAMP exerts paracrine action via adenosine receptor activation.
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J Clin Invest
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2014
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0.87
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39
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Small RNA biomarkers come of age.
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J Am Coll Cardiol
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2012
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0.87
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40
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Functional mapping of harpin HrpZ of Pseudomonas syringae reveals the sites responsible for protein oligomerization, lipid interactions and plant defence induction.
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Mol Plant Pathol
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2010
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0.87
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41
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Paradoxical resistance to myocardial ischemia and age-related cardiomyopathy in NHE1 transgenic mice: a role for ER stress?
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J Mol Cell Cardiol
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2008
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0.87
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42
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The human transcriptome is enriched for miRNA-binding sites located in cooperativity-permitting distance.
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RNA Biol
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2013
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0.85
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43
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Critical role of transcription factor cyclic AMP response element modulator in beta1-adrenoceptor-mediated cardiac dysfunction.
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Circulation
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2008
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0.85
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44
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FHL2 expression and variants in hypertrophic cardiomyopathy.
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Basic Res Cardiol
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2014
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0.84
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45
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Alterations in the myocardial creatine kinase system precede the development of contractile dysfunction in beta(1)-adrenergic receptor transgenic mice.
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J Mol Cell Cardiol
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2003
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0.81
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46
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Calcium channel function and regulation in beta 1- and beta 2-adrenoceptor transgenic mice.
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Naunyn Schmiedebergs Arch Pharmacol
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2004
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0.81
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47
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Dynamics of Gαi1 interaction with type 5 adenylate cyclase reveal the molecular basis for high sensitivity of Gi-mediated inhibition of cAMP production.
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Biochem J
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2013
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0.81
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48
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In vivo protein-protein interaction studies with BiFC: conditions, cautions, and caveats.
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Methods Mol Biol
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2014
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0.80
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49
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Self-limitation of intravenous tocolysis with beta2-adrenergic agonists is mediated through receptor G protein uncoupling.
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J Clin Endocrinol Metab
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2005
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0.80
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50
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Internet discussion forums as part of a student-centred teaching concept of pharmacology.
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GMS Z Med Ausbild
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2013
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0.80
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51
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MiR-223 is dispensable for platelet production and function in mice.
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Thromb Haemost
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2013
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0.80
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52
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Proteomics strategies in cardiovascular research.
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J Proteome Res
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2004
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0.80
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53
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Circadian and short-term regulation of blood pressure and heart rate in transgenic mice with cardiac overexpression of the beta1-adrenoceptor.
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Chronobiol Int
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2004
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0.79
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54
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G proteins: more than transducers of receptor-generated signals?
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Circ Res
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2007
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0.79
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55
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Polymorphisms determine beta-adrenoceptor conformation: implications for cardiovascular disease and therapy.
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Trends Pharmacol Sci
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2009
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0.79
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56
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Inhibition of Cullin-RING E3 ubiquitin ligase 7 by simian virus 40 large T antigen.
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Proc Natl Acad Sci U S A
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2014
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0.78
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