Inhibition of Cullin-RING E3 ubiquitin ligase 7 by simian virus 40 large T antigen.

PubWeight™: 0.78‹?›

🔗 View Article (PMC 3948260)

Published in Proc Natl Acad Sci U S A on February 18, 2014

Authors

Thomas Hartmann1, Xinsong Xu, Mira Kronast, Susanne Muehlich, Kathleen Meyer, Wolfgang Zimmermann, Jerard Hurwitz, Zhen-Qiang Pan, Stefan Engelhardt, Antonio Sarikas

Author Affiliations

1: Institute of Pharmacology and Toxicology, Technische Universität München, 80802 Munich, Germany.

Articles cited by this

The phosphatidylinositol 3-Kinase AKT pathway in human cancer. Nat Rev Cancer (2002) 28.11

Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex. Nature (2002) 10.96

Polyoma small and middle T antigens and SV40 small t antigen form stable complexes with protein phosphatase 2A. Cell (1990) 6.12

Structural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugation. Cell (2008) 6.07

IRS proteins and the common path to diabetes. Am J Physiol Endocrinol Metab (2002) 4.93

SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2. J Biol Chem (2002) 4.84

ATP-dependent assembly of double hexamers of SV40 T antigen at the viral origin of DNA replication. Nature (1989) 4.64

ERK1/2 MAP kinases: structure, function, and regulation. Pharmacol Res (2012) 3.48

Nedd8 on cullin: building an expressway to protein destruction. Oncogene (2004) 3.29

Feedback inhibition of Akt signaling limits the growth of tumors lacking Tsc2. Genes Dev (2005) 3.25

Simian virus 40 large tumor antigen is unable to transform mouse embryonic fibroblasts lacking type 1 insulin-like growth factor receptor. Proc Natl Acad Sci U S A (1993) 2.58

The cullin protein family. Genome Biol (2011) 2.43

Identification of mutations in CUL7 in 3-M syndrome. Nat Genet (2005) 2.10

T antigens of simian virus 40: molecular chaperones for viral replication and tumorigenesis. Microbiol Mol Biol Rev (2002) 1.92

Autoinhibitory regulation of SCF-mediated ubiquitination by human cullin 1's C-terminal tail. Proc Natl Acad Sci U S A (2008) 1.92

CUL7: A DOC domain-containing cullin selectively binds Skp1.Fbx29 to form an SCF-like complex. Proc Natl Acad Sci U S A (2002) 1.89

Targeted disruption of p185/Cul7 gene results in abnormal vascular morphogenesis. Proc Natl Acad Sci U S A (2003) 1.78

The CUL7 E3 ubiquitin ligase targets insulin receptor substrate 1 for ubiquitin-dependent degradation. Mol Cell (2008) 1.73

Human cytomegalovirus major immediate-early proteins and simian virus 40 large T antigen can inhibit apoptosis through activation of the phosphatidylinositide 3'-OH kinase pathway and the cellular kinase Akt. J Virol (2002) 1.67

Clinical, molecular and histopathological features of short stature syndrome with novel CUL7 mutation in Yakuts: new population isolate in Asia. J Med Genet (2007) 1.64

Cellular transformation by Simian Virus 40 and Murine Polyoma Virus T antigens. Semin Cancer Biol (2009) 1.63

Mammary tumorigenesis and metastasis caused by overexpression of insulin receptor substrate 1 (IRS-1) or IRS-2. Mol Cell Biol (2006) 1.58

Simian virus 40 large T antigen stably complexes with a 185-kilodalton host protein. J Virol (1992) 1.35

How the Rb tumor suppressor structure and function was revealed by the study of Adenovirus and SV40. Virology (2009) 1.33

Ubiquitin ligase Cbl-b is a negative regulator for insulin-like growth factor 1 signaling during muscle atrophy caused by unloading. Mol Cell Biol (2009) 1.27

Simian virus 40 large T antigen's association with the CUL7 SCF complex contributes to cellular transformation. J Virol (2005) 1.22

Cul7/p185/p193 binding to simian virus 40 large T antigen has a role in cellular transformation. J Virol (2004) 1.19

A large-scale mutation search reveals genetic heterogeneity in 3M syndrome. Eur J Hum Genet (2008) 1.19

Simian virus 40 small tumor antigen activates AKT and telomerase and induces anchorage-independent growth of human epithelial cells. J Virol (2002) 1.15

The SCF-Fbxo40 complex induces IRS1 ubiquitination in skeletal muscle, limiting IGF1 signaling. Dev Cell (2011) 1.13

Interaction between simian virus 40 large T antigen and insulin receptor substrate 1 is disrupted by the K1 mutation, resulting in the loss of large T antigen-mediated phosphorylation of Akt. J Virol (2008) 1.07

Association of insulin receptor substrate 1 with simian virus 40 large T antigen. Mol Cell Biol (1995) 1.07

Fbxw8 is essential for Cul1-Cul7 complex formation and for placental development. Mol Cell Biol (2006) 1.04

mTOR complex 2 regulates proper turnover of insulin receptor substrate-1 via the ubiquitin ligase subunit Fbw8. Mol Cell (2012) 1.03

Transformation by the simian virus 40 T antigen is regulated by IGF-I receptor and IRS-1 signaling. Oncogene (2006) 1.01

Inhibition of Rb and p53 is insufficient for SV40 T-antigen transformation. Virology (2001) 1.00

The growth-stimulatory effect of simian virus 40 T antigen requires the interaction of insulinlike growth factor 1 with its receptor. Mol Cell Biol (1992) 1.00

Identification of SV40 large T-antigen-associated proteins in cardiomyocytes from transgenic mice. Am J Physiol (1993) 0.98

A transgenic mouse line that develops early-onset invasive gastric carcinoma provides a model for carcinoembryonic antigen-targeted tumor therapy. Int J Cancer (2000) 0.92

The cullin7 E3 ubiquitin ligase: a novel player in growth control. Cell Cycle (2008) 0.90

Liver kinase b1 is required for white adipose tissue growth and differentiation. Diabetes (2013) 0.90

Evidence for a regulatory role of Cullin-RING E3 ubiquitin ligase 7 in insulin signaling. Cell Signal (2013) 0.82

Identification of the degradation determinants of insulin receptor substrate 1 for signaling cullin-RING E3 ubiquitin ligase 7-mediated ubiquitination. J Biol Chem (2012) 0.81

Expression of a neuroendocrine gene signature in gastric tumor cells from CEA 424-SV40 large T antigen-transgenic mice depends on SV40 large T antigen. PLoS One (2012) 0.78

Articles by these authors

MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts. Nature (2008) 10.73

The genome of the kinetoplastid parasite, Leishmania major. Science (2005) 8.64

MicroRNAs in the human heart: a clue to fetal gene reprogramming in heart failure. Circulation (2007) 6.41

What is the role of beta-adrenergic signaling in heart failure? Circ Res (2003) 3.22

Loading of the human 9-1-1 checkpoint complex onto DNA by the checkpoint clamp loader hRad17-replication factor C complex in vitro. Proc Natl Acad Sci U S A (2003) 2.80

Cyclic AMP imaging in adult cardiac myocytes reveals far-reaching beta1-adrenergic but locally confined beta2-adrenergic receptor-mediated signaling. Circ Res (2006) 2.66

Selective bypass of a lagging strand roadblock by the eukaryotic replicative DNA helicase. Cell (2011) 2.54

A Mammalian bromodomain protein, brd4, interacts with replication factor C and inhibits progression to S phase. Mol Cell Biol (2002) 2.51

The cullin protein family. Genome Biol (2011) 2.43

Regulation of the histone H4 monomethylase PR-Set7 by CRL4(Cdt2)-mediated PCNA-dependent degradation during DNA damage. Mol Cell (2010) 2.39

The Mdm2 RING domain C-terminus is required for supramolecular assembly and ubiquitin ligase activity. EMBO J (2006) 2.21

An open letter to Elias Zerhouni. Science (2005) 2.19

Stimulation of DNA synthesis activity of human DNA polymerase kappa by PCNA. Mol Cell Biol (2002) 2.15

Identification of mutations in CUL7 in 3-M syndrome. Nat Genet (2005) 2.10

Phytophthora infestans effector AVR3a is essential for virulence and manipulates plant immunity by stabilizing host E3 ligase CMPG1. Proc Natl Acad Sci U S A (2010) 2.07

Inhibition of p21-mediated ROS accumulation can rescue p21-induced senescence. EMBO J (2002) 2.07

A phenotypic screen to identify hypertrophy-modulating microRNAs in primary cardiomyocytes. J Mol Cell Cardiol (2011) 2.07

Analysis of receptor oligomerization by FRAP microscopy. Nat Methods (2009) 2.06

Human SHPRH is a ubiquitin ligase for Mms2-Ubc13-dependent polyubiquitylation of proliferating cell nuclear antigen. Proc Natl Acad Sci U S A (2006) 2.06

Cardiac fibroblast-derived microRNA passenger strand-enriched exosomes mediate cardiomyocyte hypertrophy. J Clin Invest (2014) 2.06

The transcriptional repressor Nab1 is a specific regulator of pathological cardiac hypertrophy. Nat Med (2005) 2.02

MicroRNA-24 regulates vascularity after myocardial infarction. Circulation (2011) 1.98

NPP1, a Phytophthora-associated trigger of plant defense in parsley and Arabidopsis. Plant J (2002) 1.93

Autoinhibitory regulation of SCF-mediated ubiquitination by human cullin 1's C-terminal tail. Proc Natl Acad Sci U S A (2008) 1.92

Autoubiquitination of the BRCA1*BARD1 RING ubiquitin ligase. J Biol Chem (2002) 1.92

Critical role for stromal interaction molecule 1 in cardiac hypertrophy. Circulation (2011) 1.91

CUL7: A DOC domain-containing cullin selectively binds Skp1.Fbx29 to form an SCF-like complex. Proc Natl Acad Sci U S A (2002) 1.89

Assembly of the Cdc45-Mcm2-7-GINS complex in human cells requires the Ctf4/And-1, RecQL4, and Mcm10 proteins. Proc Natl Acad Sci U S A (2009) 1.88

Phytotoxicity and innate immune responses induced by Nep1-like proteins. Plant Cell (2006) 1.88

The miRNA-212/132 family regulates both cardiac hypertrophy and cardiomyocyte autophagy. Nat Commun (2012) 1.88

Commensal bacteria modulate cullin-dependent signaling via generation of reactive oxygen species. EMBO J (2007) 1.86

A targeted proteomic analysis of the ubiquitin-like modifier nedd8 and associated proteins. J Proteome Res (2008) 1.74

The CUL7 E3 ubiquitin ligase targets insulin receptor substrate 1 for ubiquitin-dependent degradation. Mol Cell (2008) 1.73

DEN1 is a dual function protease capable of processing the C terminus of Nedd8 and deconjugating hyper-neddylated CUL1. J Biol Chem (2003) 1.72

Human-restricted bacterial pathogens block shedding of epithelial cells by stimulating integrin activation. Science (2010) 1.68

Human HLTF functions as a ubiquitin ligase for proliferating cell nuclear antigen polyubiquitination. Proc Natl Acad Sci U S A (2008) 1.66

The alternative Ctf18-Dcc1-Ctf8-replication factor C complex required for sister chromatid cohesion loads proliferating cell nuclear antigen onto DNA. Proc Natl Acad Sci U S A (2003) 1.62

Identification and characterization of DEN1, a deneddylase of the ULP family. J Biol Chem (2003) 1.62

Priming and extending: a UbcH5/Cdc34 E2 handoff mechanism for polyubiquitination on a SCF substrate. Mol Cell (2010) 1.61

The Nedd8-conjugated ROC1-CUL1 core ubiquitin ligase utilizes Nedd8 charged surface residues for efficient polyubiquitin chain assembly catalyzed by Cdc34. J Biol Chem (2001) 1.59

The novel human DNA helicase hFBH1 is an F-box protein. J Biol Chem (2002) 1.53

Gs activation is time-limiting in initiating receptor-mediated signaling. J Biol Chem (2006) 1.52

Evidence from comparative genomics for a complete sexual cycle in the 'asexual' pathogenic yeast Candida glabrata. Genome Biol (2003) 1.52

The genome of Streptococcus mitis B6--what is a commensal? PLoS One (2010) 1.51

Roles of PCNA-binding and ubiquitin-binding domains in human DNA polymerase eta in translesion DNA synthesis. Proc Natl Acad Sci U S A (2008) 1.47

The Cdc23 (Mcm10) protein is required for the phosphorylation of minichromosome maintenance complex by the Dfp1-Hsk1 kinase. Proc Natl Acad Sci U S A (2003) 1.47

Substrate requirements for duplex DNA translocation by the eukaryal and archaeal minichromosome maintenance helicases. J Biol Chem (2003) 1.46

A detailed look at 7 million years of genome evolution in a 439 kb contiguous sequence at the barley Hv-eIF4E locus: recombination, rearrangements and repeats. Plant J (2005) 1.45

Properties of the human Cdc45/Mcm2-7/GINS helicase complex and its action with DNA polymerase epsilon in rolling circle DNA synthesis. Proc Natl Acad Sci U S A (2012) 1.44

Real-time optical recording of beta1-adrenergic receptor activation reveals supersensitivity of the Arg389 variant to carvedilol. J Clin Invest (2007) 1.44

MiR-378 controls cardiac hypertrophy by combined repression of mitogen-activated protein kinase pathway factors. Circulation (2013) 1.42

Isolation of human Dna2 endonuclease and characterization of its enzymatic properties. Nucleic Acids Res (2006) 1.42

Fission yeast CENP-B homologs nucleate centromeric heterochromatin by promoting heterochromatin-specific histone tail modifications. Genes Dev (2002) 1.40

Primer utilization by DNA polymerase alpha-primase is influenced by its interaction with Mcm10p. J Biol Chem (2004) 1.37

Crystal structure of the GINS complex and functional insights into its role in DNA replication. Proc Natl Acad Sci U S A (2007) 1.36

CDC7 kinase phosphorylates serine residues adjacent to acidic amino acids in the minichromosome maintenance 2 protein. Proc Natl Acad Sci U S A (2006) 1.34

Cdc7-Drf1 kinase links chromosome cohesion to the initiation of DNA replication in Xenopus egg extracts. Genes Dev (2008) 1.34

Identification of a novel group of evolutionarily conserved members within the rapidly diverging murine Cea family. Genomics (2005) 1.30

Real-time monitoring of the PDE2 activity of live cells: hormone-stimulated cAMP hydrolysis is faster than hormone-stimulated cAMP synthesis. J Biol Chem (2004) 1.30

Structure of a complex between Nedd8 and the Ulp/Senp protease family member Den1. J Mol Biol (2005) 1.28

L3MBTL1 polycomb protein, a candidate tumor suppressor in del(20q12) myeloid disorders, is essential for genome stability. Proc Natl Acad Sci U S A (2010) 1.27

CEACAM1 inhibits Toll-like receptor 2-triggered antibacterial responses of human pulmonary epithelial cells. Nat Immunol (2008) 1.26

Immunoreceptor tyrosine-based activation motif phosphorylation during engulfment of Neisseria gonorrhoeae by the neutrophil-restricted CEACAM3 (CD66d) receptor. Mol Microbiol (2003) 1.25

Studies with the human cohesin establishment factor, ChlR1. Association of ChlR1 with Ctf18-RFC and Fen1. J Biol Chem (2008) 1.24

Studies on human DNA polymerase epsilon and GINS complex and their role in DNA replication. J Biol Chem (2011) 1.21

Expression of indoleamine 2,3-dioxygenase in tumor endothelial cells correlates with long-term survival of patients with renal cell carcinoma. Clin Cancer Res (2007) 1.20

Characterization of the human COP9 signalosome complex using affinity purification and mass spectrometry. J Proteome Res (2008) 1.20

Proximity-induced activation of human Cdc34 through heterologous dimerization. Proc Natl Acad Sci U S A (2005) 1.19

A novel DNA nuclease is stimulated by association with the GINS complex. Nucleic Acids Res (2011) 1.19

The ubiquitin-proteasome system: focus on the heart. Cardiovasc Res (2006) 1.17

Inhibition of p38 alpha MAPK rescues cardiomyopathy induced by overexpressed beta 2-adrenergic receptor, but not beta 1-adrenergic receptor. J Clin Invest (2007) 1.17

GPCR and G proteins: drug efficacy and activation in live cells. Mol Endocrinol (2009) 1.16

Bypass of a protein barrier by a replicative DNA helicase. Nature (2012) 1.16

Human Cdc34 employs distinct sites to coordinate attachment of ubiquitin to a substrate and assembly of polyubiquitin chains. Mol Cell Biol (2007) 1.15

A role for caspase-1 in heart failure. Circ Res (2007) 1.13

Stability of homologue of Slimb F-box protein is regulated by availability of its substrate. J Biol Chem (2004) 1.11

Comparison of different miR-21 inhibitor chemistries in a cardiac disease model. J Clin Invest (2011) 1.10

Common genomic response in different mouse models of beta-adrenergic-induced cardiomyopathy. Circulation (2003) 1.10

Influence of the human cohesion establishment factor Ctf4/AND-1 on DNA replication. J Biol Chem (2010) 1.10

The influence of the Cdc27 subunit on the properties of the Schizosaccharomyces pombe DNA polymerase delta. J Biol Chem (2002) 1.08

Structure and evolution of the mouse pregnancy-specific glycoprotein (Psg) gene locus. BMC Genomics (2005) 1.07

Cyclodextrin glucanotransferase: from gene to applications. Appl Microbiol Biotechnol (2004) 1.06

Differential gene expression identifies subgroups of renal cell carcinoma. J Lab Clin Med (2006) 1.06

Characterization of DNA primase complex isolated from the archaeon, Thermococcus kodakaraensis. J Biol Chem (2012) 1.06

Coevolution of activating and inhibitory receptors within mammalian carcinoembryonic antigen families. BMC Biol (2010) 1.05

Inactivation of VHL by tumorigenic mutations that disrupt dynamic coupling of the pVHL.hypoxia-inducible transcription factor-1alpha complex. J Biol Chem (2004) 1.05

Disruption of cardiac Ena-VASP protein localization in intercalated disks causes dilated cardiomyopathy. Am J Physiol Heart Circ Physiol (2003) 1.04

Studies of the properties of human origin recognition complex and its Walker A motif mutants. Proc Natl Acad Sci U S A (2004) 1.04

A secretion trap screen in yeast identifies protease inhibitor 16 as a novel antihypertrophic protein secreted from the heart. Circulation (2007) 1.03

A conserved interaction between the replicative clamp loader and DNA ligase in eukaryotes: implications for Okazaki fragment joining. J Biol Chem (2004) 1.03

Selective recruitment of an E2~ubiquitin complex by an E3 ubiquitin ligase. J Biol Chem (2012) 1.02

Oncogenic phosphatase Wip1 is a novel prognostic marker for lung adenocarcinoma patient survival. Cancer Sci (2011) 1.02

Disrupting the EMMPRIN (CD147)-cyclophilin A interaction reduces infarct size and preserves systolic function after myocardial ischemia and reperfusion. Arterioscler Thromb Vasc Biol (2011) 1.02

Hypoxia-induced assembly of prolyl hydroxylase PHD3 into complexes: implications for its activity and susceptibility for degradation by the E3 ligase Siah2. Biochem J (2007) 1.01

Crystal structures of two active proliferating cell nuclear antigens (PCNAs) encoded by Thermococcus kodakaraensis. Proc Natl Acad Sci U S A (2011) 1.00

Disruption of Sag/Rbx2/Roc2 induces radiosensitization by increasing ROS levels and blocking NF-kappaB activation in mouse embryonic stem cells. Free Radic Biol Med (2010) 0.99