Catabolic efficiency of aerobic glycolysis: the Warburg effect revisited.

PubWeight™: 1.88‹?› | Rank: Top 3%

🔗 View Article (PMC 2880972)

Published in BMC Syst Biol on May 06, 2010

Authors

Alexei Vazquez1, Jiangxia Liu, Yi Zhou, Zoltán N Oltvai

Author Affiliations

1: Department of Radiation Oncology, The Cancer Institute of New Jersey and UMDNJ-Robert Wood Johnson Medical School, New Brunswick, NJ 08963, USA. vazqueal@umdnj.edu

Articles citing this

Cancer metabolism: a therapeutic perspective. Nat Rev Clin Oncol (2016) 1.83

Genome-scale metabolic modeling elucidates the role of proliferative adaptation in causing the Warburg effect. PLoS Comput Biol (2011) 1.66

Amino Acids Rather than Glucose Account for the Majority of Cell Mass in Proliferating Mammalian Cells. Dev Cell (2016) 1.65

Contribution of serine, folate and glycine metabolism to the ATP, NADPH and purine requirements of cancer cells. Cell Death Dis (2013) 1.57

Glutamine-driven oxidative phosphorylation is a major ATP source in transformed mammalian cells in both normoxia and hypoxia. Mol Syst Biol (2013) 1.56

Hexokinase-2-mediated aerobic glycolysis is integral to cerebellar neurogenesis and pathogenesis of medulloblastoma. Cancer Metab (2013) 1.53

Metabolic reprogramming in macrophages and dendritic cells in innate immunity. Cell Res (2015) 1.53

Altered metabolism in cancer. BMC Biol (2010) 1.46

The Warburg Effect: How Does it Benefit Cancer Cells? Trends Biochem Sci (2016) 1.36

How metabolism generates signals during innate immunity and inflammation. J Biol Chem (2013) 1.22

Metformin inhibition of mTORC1 activation, DNA synthesis and proliferation in pancreatic cancer cells: dependence on glucose concentration and role of AMPK. Biochem Biophys Res Commun (2012) 1.19

GLUT1 expression in malignant tumors and its use as an immunodiagnostic marker. Clinics (Sao Paulo) (2011) 1.19

The metabolic demands of cancer cells are coupled to their size and protein synthesis rates. Cancer Metab (2013) 1.18

Antidiabetic Drug Metformin Prevents Progression of Pancreatic Cancer by Targeting in Part Cancer Stem Cells and mTOR Signaling. Transl Oncol (2013) 1.12

Serine biosynthesis with one carbon catabolism and the glycine cleavage system represents a novel pathway for ATP generation. PLoS One (2011) 1.08

Metabolic response of glioma to dichloroacetate measured in vivo by hyperpolarized (13)C magnetic resonance spectroscopic imaging. Neuro Oncol (2013) 1.08

Molecular crowding defines a common origin for the Warburg effect in proliferating cells and the lactate threshold in muscle physiology. PLoS One (2011) 1.06

Redox balance is key to explaining full vs. partial switching to low-yield metabolism. BMC Syst Biol (2012) 1.04

White spot syndrome virus induces metabolic changes resembling the warburg effect in shrimp hemocytes in the early stage of infection. J Virol (2011) 1.02

Cellular potts modeling of tumor growth, tumor invasion, and tumor evolution. Front Oncol (2013) 0.99

Quantitative determinants of aerobic glycolysis identify flux through the enzyme GAPDH as a limiting step. Elife (2014) 0.99

Constant growth rate can be supported by decreasing energy flux and increasing aerobic glycolysis. Cell Rep (2014) 0.98

Minimization of thermodynamic costs in cancer cell invasion. Proc Natl Acad Sci U S A (2013) 0.98

Manganese superoxide dismutase regulates a metabolic switch during the mammalian cell cycle. Cancer Res (2012) 0.96

Mechanistic target of rapamycin (mTOR): a point of convergence in the action of insulin/IGF-1 and G protein-coupled receptor agonists in pancreatic cancer cells. Front Physiol (2014) 0.93

Modeling cancer metabolism on a genome scale. Mol Syst Biol (2015) 0.92

The evolution of genome-scale models of cancer metabolism. Front Physiol (2013) 0.92

Decoupling nutrient signaling from growth rate causes aerobic glycolysis and deregulation of cell size and gene expression. Mol Biol Cell (2012) 0.91

ChREBP, a glucose-responsive transcriptional factor, enhances glucose metabolism to support biosynthesis in human cytomegalovirus-infected cells. Proc Natl Acad Sci U S A (2014) 0.90

Sirtuins Link Inflammation and Metabolism. J Immunol Res (2016) 0.90

Mathematical models of cancer metabolism. Cancer Metab (2015) 0.89

To eat or not to eat: neuronal metabolism, mitophagy, and Parkinson's disease. Antioxid Redox Signal (2011) 0.87

Carbon catabolite repression correlates with the maintenance of near invariant molecular crowding in proliferating E. coli cells. BMC Syst Biol (2013) 0.87

A Flux Balance of Glucose Metabolism Clarifies the Requirements of the Warburg Effect. Biophys J (2016) 0.86

Serine one-carbon catabolism with formate overflow. Sci Adv (2016) 0.84

Metabolic states following accumulation of intracellular aggregates: implications for neurodegenerative diseases. PLoS One (2013) 0.83

Nuclear receptors and the Warburg effect in cancer. Int J Cancer (2014) 0.83

Metabolic shifts: a fitness perspective for microbial cell factories. Biotechnol Lett (2012) 0.83

Warburg effect's manifestation in aggressive pheochromocytomas and paragangliomas: insights from a mouse cell model applied to human tumor tissue. PLoS One (2012) 0.82

Can metabolic plasticity be a cause for cancer? Warburg-Waddington legacy revisited. Clin Epigenetics (2011) 0.82

Pro-inflammatory Macrophages Sustain Pyruvate Oxidation through Pyruvate Dehydrogenase for the Synthesis of Itaconate and to Enable Cytokine Expression. J Biol Chem (2015) 0.81

Ensemble modeling of cancer metabolism. Front Physiol (2012) 0.81

Mechanistic modeling of aberrant energy metabolism in human disease. Front Physiol (2012) 0.80

The Impact of Sperm Metabolism during In Vitro Storage: The Stallion as a Model. Biomed Res Int (2016) 0.80

Emerging metabolic targets in the therapy of hematological malignancies. Biomed Res Int (2013) 0.79

Clinical significance of T cell metabolic reprogramming in cancer. Clin Transl Med (2016) 0.79

Reprogramming metabolism by targeting sirtuin 6 attenuates retinal degeneration. J Clin Invest (2016) 0.78

Triggering receptor expressed on myeloid cells and 5'adenosine monophosphate-activated protein kinase in the inflammatory response: a potential therapeutic target. Expert Rev Clin Immunol (2016) 0.77

Obesity and Diabetic Kidney Disease: Role of Oxidant Stress and Redox Balance. Antioxid Redox Signal (2016) 0.77

Metabolic requirements for cancer cell proliferation. Cancer Metab (2016) 0.77

Racial disparity in metabolic regulation of cancer. Front Biosci (Landmark Ed) (2017) 0.76

Macromolecular crowding explains overflow metabolism in cells. Sci Rep (2016) 0.76

Computational strategies for a system-level understanding of metabolism. Metabolites (2014) 0.76

Metabolic Dysfunction in Pulmonary Arterial Hypertension. Curr Hypertens Rep (2015) 0.76

Data-Driven Metabolic Pathway Compositions Enhance Cancer Survival Prediction. PLoS Comput Biol (2016) 0.75

Computational Model Predicts the Effects of Targeting Cellular Metabolism in Pancreatic Cancer. Front Physiol (2017) 0.75

Respiration gating and Bloch fitting improve pH measurements with acidoCEST MRI in an ovarian orthotopic tumor model. Proc SPIE Int Soc Opt Eng (2016) 0.75

Characterisation of bioenergetic pathways and related regulators by multiple assays in human tumour cells. Cancer Cell Int (2016) 0.75

Quantitative constraint-based computational model of tumor-to-stroma coupling via lactate shuttle. Sci Rep (2015) 0.75

Effects of Interferons and Viruses on Metabolism. Front Immunol (2016) 0.75

Sodium Nitroprusside Changed The Metabolism of Mesenchymal Stem Cells to An Anaerobic State while Viability and Proliferation Remained Intact. Cell J (2016) 0.75

Systems biology analysis of drivers underlying hallmarks of cancer cell metabolism. Sci Rep (2017) 0.75

Simulating Heterogeneous Tumor Cell Populations. PLoS One (2016) 0.75

Development of Halofluorochromic Polymer Nanoassemblies for the Potential Detection of Liver Metastatic Colorectal Cancer Tumors Using Experimental and Computational Approaches. Pharm Res (2017) 0.75

Hyperglycaemia in critically ill patients: the immune system's sweet tooth. Crit Care (2017) 0.75

Articles cited by this

Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science (2009) 49.82

On the origin of cancer cells. Science (1956) 49.55

Why do cancers have high aerobic glycolysis? Nat Rev Cancer (2004) 20.60

The biology of cancer: metabolic reprogramming fuels cell growth and proliferation. Cell Metab (2008) 18.87

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth. Nature (2008) 18.20

Creation of human tumour cells with defined genetic elements. Nature (1999) 16.47

TIGAR, a p53-inducible regulator of glycolysis and apoptosis. Cell (2006) 11.85

Tumor cell metabolism: cancer's Achilles' heel. Cancer Cell (2008) 11.18

p53 regulates mitochondrial respiration. Science (2006) 9.06

Macromolecular crowding: obvious but underappreciated. Trends Biochem Sci (2001) 8.15

Cytokine stimulation promotes glucose uptake via phosphatidylinositol-3 kinase/Akt regulation of Glut1 activity and trafficking. Mol Biol Cell (2007) 3.54

Dichloroacetate (DCA) as a potential metabolic-targeting therapy for cancer. Br J Cancer (2008) 3.39

Perturbational profiling of a cell-line model of tumorigenesis by using metabolic measurements. Proc Natl Acad Sci U S A (2005) 3.18

Cancer metabolism: facts, fantasy, and fiction. Biochem Biophys Res Commun (2004) 3.06

Macromolecular crowding: qualitative and semiquantitative successes, quantitative challenges. Biochim Biophys Acta (2003) 3.00

The role of high rates of glycolysis and glutamine utilization in rapidly dividing cells. Biosci Rep (1985) 2.73

Mitochondrial respiration defects in cancer cells cause activation of Akt survival pathway through a redox-mediated mechanism. J Cell Biol (2006) 2.68

Hypoxia signalling controls metabolic demand. Curr Opin Cell Biol (2007) 2.49

Intracellular crowding defines the mode and sequence of substrate uptake by Escherichia coli and constrains its metabolic activity. Proc Natl Acad Sci U S A (2007) 2.42

Mitochondrial DNA alterations in cancer. Cancer Invest (2002) 2.35

Mitochondrial genome instability and mtDNA depletion in human cancers. Ann N Y Acad Sci (2005) 1.97

Oxidative capacity of muscle and mitochondria: correlation of physiological, biochemical, and morphometric characteristics. Proc Natl Acad Sci U S A (1989) 1.83

Mitochondrial DNA mutations in primary leukemia cells after chemotherapy: clinical significance and therapeutic implications. Leukemia (2003) 1.76

Impact of the solvent capacity constraint on E. coli metabolism. BMC Syst Biol (2008) 1.61

Characterization of the metabolic shift between oxidative and fermentative growth in Saccharomyces cerevisiae by comparative 13C flux analysis. Microb Cell Fact (2005) 1.47

Quantitative study of mitochondria in rat liver. Dry mass, wet mass, volume, and concentration of solids. J Cell Biol (1966) 1.30

Low copy number and low oxidative damage of mitochondrial DNA are associated with tumor progression in lung cancer tissues after neoadjuvant chemotherapy. Interact Cardiovasc Thorac Surg (2008) 1.28

Studies with a reconstituted muscle glycolytic system. The rate and extent of creatine phosphorylation by anaerobic glycolysis. Biochem J (1973) 1.28

Increased OXPHOS activity precedes rise in glycolytic rate in H-RasV12/E1A transformed fibroblasts that develop a Warburg phenotype. Mol Cancer (2009) 1.20

Adaptation of mitochondrial ATP production in human skeletal muscle to endurance training and detraining. J Appl Physiol (1985) (1992) 1.18

T(3) increases mitochondrial ATP production in oxidative muscle despite increased expression of UCP2 and -3. Am J Physiol Endocrinol Metab (2001) 1.14

Calculation of volume fluctuation for globular protein models. Proc Natl Acad Sci U S A (1983) 1.08

Analysis of cellular metabolism of hybridoma cells at distinct physiological states. J Biosci Bioeng (2003) 0.97

Skeletal muscle mitochondrial ATP production rate and walking performance in peripheral arterial disease. Clin Physiol Funct Imaging (2002) 0.96

COMPARATIVE BIOCHEMISTRY HEPATOMAS. IV. ISOTOPE STUDIES OF GLUCOSE AND FRUCTOSE METABOLISM IN LIVER TUMORS OF DIFFERENT GROWTH RATES. Cancer Res (1963) 0.95

Identification of mtDNA mutations in human cancer. Methods Mol Biol (2002) 0.91

Response of mammalian cells to controlled growth rates in steady-state continuous culture. In Vitro (1975) 0.81

Distinct volume distribution of viable and non-viable hybridoma cells: A flow cytometric study. Cytotechnology (1989) 0.79

The uptake of vitamins by mouse fibroblast cells (strain LS) during growth in a chemically defined medium. J Cell Sci (1971) 0.79

Articles by these authors

Network biology: understanding the cell's functional organization. Nat Rev Genet (2004) 36.62

Treatment of HCV infection by targeting microRNA. N Engl J Med (2013) 9.91

The zebrafish reference genome sequence and its relationship to the human genome. Nature (2013) 8.52

Dynamic hepatitis C virus genotypic and phenotypic changes in patients treated with the protease inhibitor telaprevir. Gastroenterology (2007) 5.53

Synaptic mitochondria are critical for mobilization of reserve pool vesicles at Drosophila neuromuscular junctions. Neuron (2005) 4.87

Functional and topological characterization of protein interaction networks. Proteomics (2004) 4.57

ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization. Proc Natl Acad Sci U S A (2009) 4.46

Hrs regulates endosome membrane invagination and tyrosine kinase receptor signaling in Drosophila. Cell (2002) 3.72

Genetic analysis of cavefish reveals molecular convergence in the evolution of albinism. Nat Genet (2005) 3.66

Minimum information specification for in situ hybridization and immunohistochemistry experiments (MISFISHIE). Nat Biotechnol (2008) 3.43

Intra-aortic balloon counterpulsation and infarct size in patients with acute anterior myocardial infarction without shock: the CRISP AMI randomized trial. JAMA (2011) 3.28

The v-ATPase V0 subunit a1 is required for a late step in synaptic vesicle exocytosis in Drosophila. Cell (2005) 3.05

Drosophila parkin mutants have decreased mass and cell size and increased sensitivity to oxygen radical stress. Development (2004) 3.03

Mitoferrin is essential for erythroid iron assimilation. Nature (2006) 2.99

Synaptojanin is recruited by endophilin to promote synaptic vesicle uncoating. Neuron (2003) 2.96

The cdx genes and retinoic acid control the positioning and segmentation of the zebrafish pronephros. PLoS Genet (2007) 2.85

RNA-mediated epigenetic programming of a genome-rearrangement pathway. Nature (2007) 2.79

Drosophila NMNAT maintains neural integrity independent of its NAD synthesis activity. PLoS Biol (2006) 2.70

Manipulating surface states in topological insulator nanoribbons. Nat Nanotechnol (2011) 2.70

Natural prevalence of hepatitis C virus variants with decreased sensitivity to NS3.4A protease inhibitors in treatment-naive subjects. J Infect Dis (2008) 2.69

Exosomes mediate the cell-to-cell transmission of IFN-α-induced antiviral activity. Nat Immunol (2013) 2.64

Endophilin mutations block clathrin-mediated endocytosis but not neurotransmitter release. Cell (2002) 2.43

Aggregation of topological motifs in the Escherichia coli transcriptional regulatory network. BMC Bioinformatics (2004) 2.41

The zinc finger transcription factor Gfi1, implicated in lymphomagenesis, is required for inner ear hair cell differentiation and survival. Development (2003) 2.38

Mutations in Drosophila sec15 reveal a function in neuronal targeting for a subset of exocyst components. Neuron (2005) 2.33

TIF1gamma controls erythroid cell fate by regulating transcription elongation. Cell (2010) 2.33

A zebrafish bmyb mutation causes genome instability and increased cancer susceptibility. Proc Natl Acad Sci U S A (2005) 2.19

Mutant-specific gene programs in the zebrafish. Blood (2005) 2.15

The Oxytricha trifallax macronuclear genome: a complex eukaryotic genome with 16,000 tiny chromosomes. PLoS Biol (2013) 2.08

Castanospermine, a potent inhibitor of dengue virus infection in vitro and in vivo. J Virol (2005) 1.97

Genome-scale identification of conditionally essential genes in E. coli by DNA microarrays. Biochem Biophys Res Commun (2004) 1.69

The activity reaction core and plasticity of metabolic networks. PLoS Comput Biol (2005) 1.66

The zebrafish moonshine gene encodes transcriptional intermediary factor 1gamma, an essential regulator of hematopoiesis. PLoS Biol (2004) 1.64

Eps15 and Dap160 control synaptic vesicle membrane retrieval and synapse development. J Cell Biol (2007) 1.64

Long-lasting novelty-induced neuronal reverberation during slow-wave sleep in multiple forebrain areas. PLoS Biol (2004) 1.62

Lysosomal enzyme cathepsin D protects against alpha-synuclein aggregation and toxicity. Mol Brain (2008) 1.61

Spurious spatial periodicity of co-expression in microarray data due to printing design. Nucleic Acids Res (2003) 1.61

Impact of the solvent capacity constraint on E. coli metabolism. BMC Syst Biol (2008) 1.61

Spike sorting based on automatic template reconstruction with a partial solution to the overlapping problem. J Neurosci Methods (2004) 1.54

Bioinformatics analysis of experimentally determined protein complexes in the yeast Saccharomyces cerevisiae. Genome Res (2003) 1.53

Aberrant lysosomal carbohydrate storage accompanies endocytic defects and neurodegeneration in Drosophila benchwarmer. J Cell Biol (2005) 1.52

Comparative genome-scale metabolic reconstruction and flux balance analysis of multiple Staphylococcus aureus genomes identify novel antimicrobial drug targets. J Bacteriol (2009) 1.51

Activity-independent prespecification of synaptic partners in the visual map of Drosophila. Curr Biol (2006) 1.50

Distribution of Bim determines Mcl-1 dependence or codependence with Bcl-xL/Bcl-2 in Mcl-1-expressing myeloma cells. Blood (2011) 1.47

The zebra fish cassiopeia mutant reveals that SIL is required for mitotic spindle organization. Mol Cell Biol (2007) 1.47

Definition of the zebrafish genome using flow cytometry and cytogenetic mapping. BMC Genomics (2007) 1.46

Genetic silencing of Nox2 and Nox4 reveals differential roles of these NADPH oxidase homologues in the vasopressor and dipsogenic effects of brain angiotensin II. Hypertension (2009) 1.45

Multi-color CD34⁺ progenitor-focused flow cytometric assay in evaluation of myelodysplastic syndromes in patients with post cancer therapy cytopenia. Leuk Res (2012) 1.44

The zebrafish van gogh mutation disrupts tbx1, which is involved in the DiGeorge deletion syndrome in humans. Development (2003) 1.43

Subversion of cellular autophagy machinery by hepatitis B virus for viral envelopment. J Virol (2011) 1.41

A semi-supervised method for predicting transcription factor-gene interactions in Escherichia coli. PLoS Comput Biol (2008) 1.40

Cell-specific mitotic defect and dyserythropoiesis associated with erythroid band 3 deficiency. Nat Genet (2003) 1.40

Endophilin promotes a late step in endocytosis at glial invaginations in Drosophila photoreceptor terminals. J Neurosci (2003) 1.37

High-throughput cell transplantation establishes that tumor-initiating cells are abundant in zebrafish T-cell acute lymphoblastic leukemia. Blood (2010) 1.34

Zebrafish globin switching occurs in two developmental stages and is controlled by the LCR. Dev Biol (2012) 1.32

Hematopoietic gene expression profile in zebrafish kidney marrow. Proc Natl Acad Sci U S A (2004) 1.31

Isolation and characterization of runxa and runxb, zebrafish members of the runt family of transcriptional regulators. Exp Hematol (2002) 1.31

The Zon laboratory guide to positional cloning in zebrafish. Methods Cell Biol (2004) 1.30

The zebrafish dag1 mutant: a novel genetic model for dystroglycanopathies. Hum Mol Genet (2011) 1.30

Disparate evolution of prion protein domains and the distinct origin of Doppel- and prion-related loci revealed by fish-to-mammal comparisons. FASEB J (2005) 1.29

The eag potassium channel binds and locally activates calcium/calmodulin-dependent protein kinase II. J Biol Chem (2003) 1.29

Development of the Minimum Information Specification for In Situ Hybridization and Immunohistochemistry Experiments (MISFISHIE). OMICS (2006) 1.26

Glyceraldehyde-3-phosphate dehydrogenase binds to the AU-Rich 3' untranslated region of colony-stimulating factor-1 (CSF-1) messenger RNA in human ovarian cancer cells: possible role in CSF-1 posttranscriptional regulation and tumor phenotype. Cancer Res (2005) 1.25

Network of coregulated spliceosome components revealed by zebrafish mutant in recycling factor p110. Proc Natl Acad Sci U S A (2007) 1.24

Genetic analysis and characterization of a new maize association mapping panel for quantitative trait loci dissection. Theor Appl Genet (2010) 1.23

Human Mre11/human Rad50/Nbs1 and DNA ligase IIIalpha/XRCC1 protein complexes act together in an alternative nonhomologous end joining pathway. J Biol Chem (2011) 1.21

Critical regulation of miR-200/ZEB2 pathway in Oct4/Sox2-induced mesenchymal-to-epithelial transition and induced pluripotent stem cell generation. Proc Natl Acad Sci U S A (2013) 1.21

The zebrafish runzel muscular dystrophy is linked to the titin gene. Dev Biol (2007) 1.20

Presynaptic ryanodine receptor-activated calmodulin kinase II increases vesicle mobility and potentiates neuropeptide release. J Neurosci (2007) 1.19

The metabolic demands of cancer cells are coupled to their size and protein synthesis rates. Cancer Metab (2013) 1.18

Zebrafish narrowminded disrupts the transcription factor prdm1 and is required for neural crest and sensory neuron specification. Dev Biol (2005) 1.16

The zebrafish mutant gene chardonnay (cdy) encodes divalent metal transporter 1 (DMT1). Blood (2002) 1.16

Delta-sarcoglycan is required for early zebrafish muscle organization. Exp Cell Res (2004) 1.16

Genetic and epigenetic down-regulation of microRNA-212 promotes colorectal tumor metastasis via dysregulation of MnSOD. Gastroenterology (2013) 1.16

RARα2 expression confers myeloma stem cell features. Blood (2013) 1.15

A genetic and developmental pathway from STAT3 to the OCT4-NANOG circuit is essential for maintenance of ICM lineages in vivo. Genes Dev (2013) 1.13

A reversed CD4/CD8 ratio of tumor-infiltrating lymphocytes and a high percentage of CD4(+)FOXP3(+) regulatory T cells are significantly associated with clinical outcome in squamous cell carcinoma of the cervix. Cell Mol Immunol (2010) 1.13

Complete genomic sequence of Chinese virulent duck enteritis virus. J Virol (2012) 1.11

Silencing nox4 in the paraventricular nucleus improves myocardial infarction-induced cardiac dysfunction by attenuating sympathoexcitation and periinfarct apoptosis. Circ Res (2010) 1.10

Zebrafish orthologs of human muscular dystrophy genes. BMC Genomics (2007) 1.10

Models of brainstem responses to bilateral electrical stimulation. J Assoc Res Otolaryngol (2008) 1.10

HSP72 attenuates renal tubular cell apoptosis and interstitial fibrosis in obstructive nephropathy. Am J Physiol Renal Physiol (2008) 1.10

The pathway to detangle a scrambled gene. PLoS One (2008) 1.09

Mitochondrial Atpif1 regulates haem synthesis in developing erythroblasts. Nature (2012) 1.09

Coherent magnetic semiconductor nanodot arrays. Nanoscale Res Lett (2011) 1.09

Serine biosynthesis with one carbon catabolism and the glycine cleavage system represents a novel pathway for ATP generation. PLoS One (2011) 1.08

Evolutionary conservation of zebrafish linkage group 14 with frequently deleted regions of human chromosome 5 in myeloid malignancies. Proc Natl Acad Sci U S A (2002) 1.08

Structure and function of the two tandem WW domains of the pre-mRNA splicing factor FBP21 (formin-binding protein 21). J Biol Chem (2009) 1.07

A phase II study of biweekly paclitaxel and cisplatin chemotherapy for recurrent or metastatic esophageal squamous cell carcinoma: ERCC1 expression predicts response to chemotherapy. Med Oncol (2012) 1.06

Molecular crowding defines a common origin for the Warburg effect in proliferating cells and the lactate threshold in muscle physiology. PLoS One (2011) 1.06

Immunophenotypic heterogeneity of normal plasma cells: comparison with minimal residual plasma cell myeloma. J Clin Pathol (2012) 1.06

miR-34b regulates multiciliogenesis during organ formation in zebrafish. Development (2013) 1.06

Scanning ion conductance microscopy. Annu Rev Anal Chem (Palo Alto Calif) (2012) 1.05

The role and regulation of friend of GATA-1 (FOG-1) during blood development in the zebrafish. Blood (2009) 1.05

14-3-3 proteins in neurological disorders. Int J Biochem Mol Biol (2012) 1.05

Zebrafish mutants with disrupted early T-cell and thymus development identified in early pressure screen. Dev Dyn (2008) 1.04

Altered baseline brain activity in type 2 diabetes: a resting-state fMRI study. Psychoneuroendocrinology (2013) 1.04

Pattern of distribution and cycling of SLOB, Slowpoke channel binding protein, in Drosophila. BMC Neurosci (2004) 1.03

Association of serum omentin-1 levels with coronary artery disease. Acta Pharmacol Sin (2011) 1.03