Published in Arch Otolaryngol Head Neck Surg on May 01, 2010
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Hyaluronan-CD44v3 interaction with Oct4-Sox2-Nanog promotes miR-302 expression leading to self-renewal, clonal formation, and cisplatin resistance in cancer stem cells from head and neck squamous cell carcinoma. J Biol Chem (2012) 1.57
Hyaluronan-CD44 interaction promotes c-Src-mediated twist signaling, microRNA-10b expression, and RhoA/RhoC up-regulation, leading to Rho-kinase-associated cytoskeleton activation and breast tumor cell invasion. J Biol Chem (2010) 1.56
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A CD44 survival pathway triggers chemoresistance via lyn kinase and phosphoinositide 3-kinase/Akt in colon carcinoma cells. Cancer Res (2001) 1.53
Hyaluronan promotes CD44v3-Vav2 interaction with Grb2-p185(HER2) and induces Rac1 and Ras signaling during ovarian tumor cell migration and growth. J Biol Chem (2001) 1.45
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Hyaluronan and the interaction between CD44 and epidermal growth factor receptor in oncogenic signaling and chemotherapy resistance in head and neck cancer. Arch Otolaryngol Head Neck Surg (2006) 1.39
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AKT involvement in cisplatin chemoresistance of human uterine cancer cells. Gynecol Oncol (2004) 1.22
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The influence of hyaluronan-CD44 interaction on topoisomerase II activity and etoposide cytotoxicity in head and neck cancer. Arch Otolaryngol Head Neck Surg (2007) 1.04
Hyaluronan-CD44 promotes phospholipase C-mediated Ca2+ signaling and cisplatin resistance in head and neck cancer. Arch Otolaryngol Head Neck Surg (2006) 1.04
Association of CD44 V3-containing isoforms with tumor cell growth, migration, matrix metalloproteinase expression, and lymph node metastasis in head and neck cancer. Head Neck (2007) 1.03
CD44v10 interaction with Rho-kinase (ROK) activates inositol 1,4,5-triphosphate (IP3) receptor-mediated Ca2+ signaling during hyaluronan (HA)-induced endothelial cell migration. Cell Motil Cytoskeleton (2002) 1.00
Signaling pathways required for matrix metalloproteinase-9 induction by betacellulin in head-and-neck squamous carcinoma cells. Int J Cancer (2004) 0.97
Small GTP-binding protein, Rho, both increased and decreased cellular motility, activation of matrix metalloproteinase 2 and invasion of human osteosarcoma cells. Jpn J Cancer Res (2001) 0.97
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Hyaluronan-CD44 interaction activates stem cell marker Nanog, Stat-3-mediated MDR1 gene expression, and ankyrin-regulated multidrug efflux in breast and ovarian tumor cells. J Biol Chem (2008) 2.42
Tumor necrosis factor {alpha} reversibly disrupts the blood-testis barrier and impairs Sertoli-germ cell adhesion in the seminiferous epithelium of adult rat testes. J Endocrinol (2006) 1.66
(-)-gossypol inhibits growth and promotes apoptosis of human head and neck squamous cell carcinoma in vivo. Neoplasia (2006) 1.55
Role of hyaluronan-mediated CD44 signaling in head and neck squamous cell carcinoma progression and chemoresistance. Am J Pathol (2011) 1.44
Hyaluronan and the interaction between CD44 and epidermal growth factor receptor in oncogenic signaling and chemotherapy resistance in head and neck cancer. Arch Otolaryngol Head Neck Surg (2006) 1.39
CD44 variant isoforms in head and neck squamous cell carcinoma progression. Laryngoscope (2009) 1.37
CD44 interaction with ankyrin and IP3 receptor in lipid rafts promotes hyaluronan-mediated Ca2+ signaling leading to nitric oxide production and endothelial cell adhesion and proliferation. Exp Cell Res (2004) 1.26
Matrix metalloproteinase-9 facilitates glial scar formation in the injured spinal cord. J Neurosci (2008) 1.23
Calcium-induced human keratinocyte differentiation requires src- and fyn-mediated phosphatidylinositol 3-kinase-dependent activation of phospholipase C-gamma1. Mol Biol Cell (2005) 1.23
Dynamin II interacts with the cadherin- and occludin-based protein complexes at the blood-testis barrier in adult rat testes. J Endocrinol (2006) 1.21
Regulation of ectoplasmic specialization dynamics in the seminiferous epithelium by focal adhesion-associated proteins in testosterone-suppressed rat testes. Endocrinology (2004) 1.20
A mesoporous silica nanoparticle--PEI--fusogenic peptide system for siRNA delivery in cancer therapy. Biomaterials (2012) 1.08
NAD(+) administration decreases ischemic brain damage partially by blocking autophagy in a mouse model of brain ischemia. Neurosci Lett (2012) 1.06
Hyaluronan increases RANKL expression in bone marrow stromal cells through CD44. J Bone Miner Res (2004) 1.04
Hyaluronan-CD44 promotes phospholipase C-mediated Ca2+ signaling and cisplatin resistance in head and neck cancer. Arch Otolaryngol Head Neck Surg (2006) 1.04
Association of CD44 V3-containing isoforms with tumor cell growth, migration, matrix metalloproteinase expression, and lymph node metastasis in head and neck cancer. Head Neck (2007) 1.03
The packaging of siRNA within the mesoporous structure of silica nanoparticles. Biomaterials (2011) 1.02
NAD+ metabolism and NAD(+)-dependent enzymes: promising therapeutic targets for neurological diseases. Curr Drug Targets (2012) 1.02
SIRT2 activity is required for the survival of C6 glioma cells. Biochem Biophys Res Commun (2011) 1.01
Adjudin attenuates lipopolysaccharide (LPS)- and ischemia-induced microglial activation. J Neuroimmunol (2012) 1.01
CD44v10 interaction with Rho-kinase (ROK) activates inositol 1,4,5-triphosphate (IP3) receptor-mediated Ca2+ signaling during hyaluronan (HA)-induced endothelial cell migration. Cell Motil Cytoskeleton (2002) 1.00
Downregulation of Fanconi anemia genes in sporadic head and neck squamous cell carcinoma. ORL J Otorhinolaryngol Relat Spec (2007) 0.97
Interaction of low molecular weight hyaluronan with CD44 and toll-like receptors promotes the actin filament-associated protein 110-actin binding and MyD88-NFκB signaling leading to proinflammatory cytokine/chemokine production and breast tumor invasion. Cytoskeleton (Hoboken) (2011) 0.96
Electrophysiologic facial nerve monitoring during parotidectomy. Head Neck (2010) 0.96
Restoration of the orbital aesthetic subunit in complex midface defects. Laryngoscope (2004) 0.95
Selective matrix (hyaluronan) interaction with CD44 and RhoGTPase signaling promotes keratinocyte functions and overcomes age-related epidermal dysfunction. J Dermatol Sci (2013) 0.94
Silencing of SIRT2 induces cell death and a decrease in the intracellular ATP level of PC12 cells. Int J Physiol Pathophysiol Pharmacol (2011) 0.93
Magnetic field enhanced cell uptake efficiency of magnetic silica mesoporous nanoparticles. Nanoscale (2012) 0.92
FTY720, a synthetic compound from Isaria sinclairii, inhibits proliferation and induces apoptosis in pancreatic cancer cells. Cancer Lett (2007) 0.91
Oxidative stress and PARP activation mediate the NADH-induced decrease in glioma cell survival. Int J Physiol Pathophysiol Pharmacol (2010) 0.90
TP53 and CDKN2a mutations in never-smoker oral tongue squamous cell carcinoma. Laryngoscope (2014) 0.89
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The β1-integrin-p-FAK-p130Cas-DOCK180-RhoA-vinculin is a novel regulatory protein complex at the apical ectoplasmic specialization in adult rat testes. Spermatogenesis (2011) 0.88
Quality-of-life impact of participation in a head and neck cancer support group. Otolaryngol Head Neck Surg (2007) 0.87
CD38 is a key enzyme for the survival of mouse microglial BV2 cells. Biochem Biophys Res Commun (2012) 0.86
Delivering hydrophilic and hydrophobic chemotherapeutics simultaneously by magnetic mesoporous silica nanoparticles to inhibit cancer cells. Int J Nanomedicine (2012) 0.86
Male contraceptive Adjudin is a potential anti-cancer drug. Biochem Pharmacol (2012) 0.86
A novel intravital method to evaluate cerebral vasospasm in rat models of subarachnoid hemorrhage: a study with synchrotron radiation angiography. PLoS One (2012) 0.85
Essential role of the electroneutral Na+-HCO3- cotransporter NBCn1 in murine duodenal acid-base balance and colonic mucus layer build-up in vivo. J Physiol (2013) 0.85
The distinct roles of anion transporters Slc26a3 (DRA) and Slc26a6 (PAT-1) in fluid and electrolyte absorption in the murine small intestine. Pflugers Arch (2014) 0.84
Full-thickness skin graft from the groin for coverage of the radial forearm free flap donor site. Am J Otolaryngol (2007) 0.84
Beta2-adrenoceptors and non-beta-adrenoceptors mediate effects of BRL37344 and clenbuterol on glucose uptake in soleus muscle: studies using knockout mice. Br J Pharmacol (2009) 0.84
Perinatal supplementation with omega-3 polyunsaturated fatty acids improves sevoflurane-induced neurodegeneration and memory impairment in neonatal rats. PLoS One (2013) 0.83
Adjudin-mediated junction restructuring in the seminiferous epithelium leads to displacement of soluble guanylate cyclase from adherens junctions. J Cell Physiol (2006) 0.83
Radial forearm free tissue transfer reduces complications in salvage skull base surgery. Otolaryngol Head Neck Surg (2004) 0.83
Regulation of SIRT2 levels for human non-small cell lung cancer therapy. Lung Cancer (2013) 0.83
Role of panendoscopy to identify synchronous second primary malignancies in patients with oral cavity and oropharyngeal squamous cell carcinoma. Head Neck (2010) 0.83
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Diagnosis of Bilateral Tonsil Cancers via Staging PET/CT: Case Report and Review. Int J Otolaryngol (2011) 0.82
Cellular localization of sphingomyelin synthase 2 in the seminiferous epithelium of adult rat testes. J Endocrinol (2007) 0.82
NAD(+) administration significantly attenuates synchrotron radiation X-ray-induced DNA damage and structural alterations of rodent testes. Int J Physiol Pathophysiol Pharmacol (2012) 0.82
Interactions between synchrotron radiation X-ray and biological tissues - theoretical and clinical significance. Int J Physiol Pathophysiol Pharmacol (2011) 0.82
Predictors of quality of life after treatment for oral cavity and oropharyngeal carcinoma. Otolaryngol Head Neck Surg (2008) 0.82
Insights into the mechanism of magnetofection using MNPs-PEI/pDNA/free PEI magnetofectins. Int J Pharm (2011) 0.81
Infrahyoid myocutaneous flap for medium-sized head and neck defects: surgical outcome and technique modification. Otolaryngol Head Neck Surg (2012) 0.81
Roles of oxidative stress in synchrotron radiation X-ray-induced testicular damage of rodents. Int J Physiol Pathophysiol Pharmacol (2012) 0.80
Rab4A GTPase catenin interactions are involved in cell junction dynamics in the testis. J Androl (2007) 0.79
Limited utility of routine surveillance MRI following chemoradiation for advanced-stage oropharynx carcinoma. Int J Otolaryngol (2010) 0.79
Oral tongue squamous cell carcinoma in never-smokers: analysis of clinicopathologic characteristics and survival. Otolaryngol Head Neck Surg (2013) 0.79
Recombinant human erythropoietin pretreatment attenuates acute renal tubular injury against ischemia-reperfusion by restoring transient receptor potential channel-6 expression and function in collecting ducts. Crit Care Med (2014) 0.79
Role of Kinase Epidermal Growth Factor Receptor and SRC in the Caerulein-Induced Acute Pancreatitis in Mice. Pancreas (2015) 0.78
New strategies for the prevention of stroke. Clin Exp Pharmacol Physiol (2009) 0.78
Role of hyaluronan synthase 2 to promote CD44-dependent oral cavity squamous cell carcinoma progression. Head Neck (2012) 0.78
The role of CD44 in cutaneous inflammation. Exp Dermatol (2009) 0.78
Improved outcomes in adjuvant radiotherapy for oral cavity carcinoma at an academic center: a matched-pair analysis. Laryngoscope (2014) 0.77
NAD+ treatment induces delayed autophagy in Neuro2a cells partially by increasing oxidative stress. Neurochem Res (2011) 0.77
Image processing tools for alpha-particle track-etch dosimetry. Cancer Biother Radiopharm (2003) 0.77
Recombinant human erythropoietin pretreatment alleviates renal glomerular injury induced by cardiopulmonary bypass by reducing transient receptor potential channel 6-nuclear factor of activated T-cells pathway activation. J Thorac Cardiovasc Surg (2013) 0.77
Differential association of the Na+/H+ Exchanger Regulatory Factor (NHERF) family of adaptor proteins with the raft- and the non-raft brush border membrane fractions of NHE3. Cell Physiol Biochem (2013) 0.77
Towards magnetic-enhanced cellular uptake, MRI and chemotherapeutics delivery by magnetic mesoporous silica nanoparticles. J Nanosci Nanotechnol (2012) 0.77
Oral cavity squamous cell carcinoma in never smokers: analysis of clinicopathologic characteristics and survival. Am J Otolaryngol (2013) 0.77
Cell detection in phase-contrast images used for alpha-particle track-etch dosimetry: a semi-automated approach. Phys Med Biol (2005) 0.76
NAD+ treatment decreases tumor cell survival by inducing oxidative stress. Front Biosci (Elite Ed) (2011) 0.76
NADPH treatment decreases C6 glioma cell survival by increasing oxidative stress. Front Biosci (Elite Ed) (2011) 0.76
Interaction of oligomeric breast cancer resistant protein (BCRP) with adjudin: a male contraceptive with anti-cancer activity. Curr Mol Pharmacol (2014) 0.76
Adjudin disrupts spermatogenesis by targeting drug transporters: Lesson from the breast cancer resistance protein (BCRP). Spermatogenesis (2013) 0.76
Rare complication after thyroidectomy-cervical esophageal stenosis: a case report and literature review. World J Surg Oncol (2014) 0.75
Identifying and improving knowledge deficits of emergency airway management of tracheotomy and laryngectomy patients: a pilot patient safety initiative. Int J Otolaryngol (2010) 0.75
Effective Delivery of Male Contraceptives Behind the Blood-Testis Barrier (BTB) - Lesson from Adjudin. Curr Med Chem (2016) 0.75
Iatrogenic bilateral inverted papilloma: case report and literature review. J Otolaryngol (2007) 0.75
Binary methods for the microdosimetric analysis of cell survival data from alpha-particle irradiation. Cancer Biother Radiopharm (2003) 0.75
Stepwise regional and distant progression of recurrent pleomorphic adenoma. J Otolaryngol Head Neck Surg (2011) 0.75
Simulation of binary methods for the microdosimetric analysis of cell survival after alpha-particle irradiation: ability to distinguish between different models. Radiat Res (2004) 0.75
Combined modality treatment outcomes for head and neck cancer: comparison of postoperative radiation therapy at academic vs nonacademic medical centers. JAMA Otolaryngol Head Neck Surg (2013) 0.75
Management of advanced nodal disease following chemoradiation for head and neck squamous cell carcinoma: role of magnetic resonance imaging. J Otolaryngol (2007) 0.75
The Limitations of Routine Magnetic Resonance Imaging for Long-Term Post-Treatment Locoregional Surveillance of Salivary Carcinoma. ORL J Otorhinolaryngol Relat Spec (2015) 0.75
Minicricothyrotomy approach with fiberoptic guidance for management of posterior glottic stenosis. Laryngoscope (2007) 0.75
Adjudin - A Male Contraceptive with Other Biological Activities. Recent Pat Endocr Metab Immune Drug Discov (2015) 0.75