John P Cooke

Author PubWeight™ 177.07‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Unexpected effect of proton pump inhibitors: elevation of the cardiovascular risk factor asymmetric dimethylarginine. Circulation 2013 3.45
2 Statins have biphasic effects on angiogenesis. Circulation 2002 3.39
3 Relationship between insulin resistance and an endogenous nitric oxide synthase inhibitor. JAMA 2002 3.20
4 Activation of innate immunity is required for efficient nuclear reprogramming. Cell 2012 2.99
5 Beta2-microglobulin as a biomarker in peripheral arterial disease: proteomic profiling and clinical studies. Circulation 2007 2.72
6 Nonbone marrow-derived circulating progenitor cells contribute to postnatal neovascularization following tissue ischemia. Circ Res 2007 2.71
7 Impaired nitric oxide synthase pathway in diabetes mellitus: role of asymmetric dimethylarginine and dimethylarginine dimethylaminohydrolase. Circulation 2002 2.65
8 Endothelial dysfunction induced by hyperhomocyst(e)inemia: role of asymmetric dimethylarginine. Circulation 2003 2.30
9 Differentiation, survival, and function of embryonic stem cell derived endothelial cells for ischemic heart disease. Circulation 2007 2.21
10 A novel angiogenic pathway mediated by non-neuronal nicotinic acetylcholine receptors. J Clin Invest 2002 2.19
11 Second hand smoke stimulates tumor angiogenesis and growth. Cancer Cell 2003 2.17
12 Nitric oxide inhibition as a mechanism for blood pressure increase during salt loading in normotensive postmenopausal women. J Hypertens 2003 2.04
13 Nicotine strongly activates dendritic cell-mediated adaptive immunity: potential role for progression of atherosclerotic lesions. Circulation 2003 1.98
14 L-arginine supplementation in peripheral arterial disease: no benefit and possible harm. Circulation 2007 1.97
15 Endothelial cells derived from human iPSCS increase capillary density and improve perfusion in a mouse model of peripheral arterial disease. Arterioscler Thromb Vasc Biol 2011 1.93
16 Symmetric dimethylarginine (SDMA) as endogenous marker of renal function--a meta-analysis. Nephrol Dial Transplant 2006 1.90
17 ADMA increases arterial stiffness and decreases cerebral blood flow in humans. Stroke 2006 1.88
18 Alternative ankle-brachial index method identifies additional at-risk individuals. J Am Coll Cardiol 2013 1.86
19 Dimethylarginine dimethylaminohydrolase regulates nitric oxide synthesis: genetic and physiological evidence. Circulation 2003 1.84
20 Murine model of hindlimb ischemia. J Vis Exp 2009 1.82
21 Bone morphogenetic protein 2 induces pulmonary angiogenesis via Wnt-beta-catenin and Wnt-RhoA-Rac1 pathways. J Cell Biol 2009 1.77
22 Multifunctional in vivo vascular imaging using near-infrared II fluorescence. Nat Med 2012 1.74
23 Endothelial progenitor cells participate in nicotine-mediated angiogenesis. J Am Coll Cardiol 2006 1.70
24 Adenoviral gene transfer with soluble vascular endothelial growth factor receptors impairs angiogenesis and perfusion in a murine model of hindlimb ischemia. Circulation 2004 1.69
25 Stem cell therapy for vascular regeneration: adult, embryonic, and induced pluripotent stem cells. Circulation 2010 1.67
26 Cytomegalovirus infection impairs the nitric oxide synthase pathway: role of asymmetric dimethylarginine in transplant arteriosclerosis. Circulation 2004 1.62
27 Conversion of human fibroblasts to functional endothelial cells by defined factors. Arterioscler Thromb Vasc Biol 2013 1.61
28 Nitric oxide and angiogenesis. Circulation 2002 1.56
29 Microenvironmental VEGF distribution is critical for stable and functional vessel growth in ischemia. FASEB J 2006 1.54
30 Nicotine accelerates angiogenesis and wound healing in genetically diabetic mice. Am J Pathol 2002 1.54
31 Embryonic stem cell-derived endothelial cells for treatment of hindlimb ischemia. J Vis Exp 2009 1.49
32 Antioxidant vitamins C and E improve endothelial function in children with hyperlipidemia: Endothelial Assessment of Risk from Lipids in Youth (EARLY) Trial. Circulation 2003 1.49
33 T-cell immunity to subclinical cytomegalovirus infection reduces cardiac allograft disease. Circulation 2006 1.46
34 Embryonic stem cell-derived endothelial cells engraft into the ischemic hindlimb and restore perfusion. Arterioscler Thromb Vasc Biol 2010 1.42
35 Nicotine promotes arteriogenesis. J Am Coll Cardiol 2003 1.42
36 Determination of asymmetric dimethylarginine (ADMA) using a novel ELISA assay. Clin Chem Lab Med 2004 1.41
37 Overexpression of dimethylarginine dimethylaminohydrolase reduces tissue asymmetric dimethylarginine levels and enhances angiogenesis. Circulation 2005 1.35
38 Limited gene expression variation in human embryonic stem cell and induced pluripotent stem cell-derived endothelial cells. Stem Cells 2013 1.29
39 Association between chromosome 9p21 variants and the ankle-brachial index identified by a meta-analysis of 21 genome-wide association studies. Circ Cardiovasc Genet 2011 1.26
40 Asymmetric dimethyl L-arginine (ADMA) is a critical regulator of myocardial reperfusion injury. Cardiovasc Res 2007 1.25
41 Limb hemodynamics are not predictive of functional capacity in patients with PAD. Vasc Med 2006 1.22
42 Human induced pluripotent stem cell-derived endothelial cells exhibit functional heterogeneity. Am J Transl Res 2013 1.18
43 Low lifetime recreational activity is a risk factor for peripheral arterial disease. J Vasc Surg 2011 1.18
44 The emerging role of the thioredoxin system in angiogenesis. Arterioscler Thromb Vasc Biol 2010 1.18
45 Dimethylarginine dimethylaminohydrolase overexpression enhances insulin sensitivity. Arterioscler Thromb Vasc Biol 2008 1.16
46 Acute rejection and cardiac allograft vascular disease is reduced by suppression of subclinical cytomegalovirus infection. Transplantation 2006 1.11
47 Exercise capacity is the strongest predictor of mortality in patients with peripheral arterial disease. J Vasc Surg 2012 1.10
48 A central role for nicotinic cholinergic regulation of growth factor-induced endothelial cell migration. Arterioscler Thromb Vasc Biol 2006 1.10
49 Genetic susceptibility to peripheral arterial disease: a dark corner in vascular biology. Arterioscler Thromb Vasc Biol 2007 1.09
50 Dimethylarginine dimethylaminohydrolase overexpression suppresses graft coronary artery disease. Circulation 2005 1.08
51 Overexpression of dimethylarginine dimethylaminohydrolase inhibits asymmetric dimethylarginine-induced endothelial dysfunction in the cerebral circulation. Stroke 2007 1.07
52 Endothelial determinants of dendritic cell adhesion and migration: new implications for vascular diseases. Arterioscler Thromb Vasc Biol 2002 1.06
53 Mecamylamine suppresses Basal and nicotine-stimulated choroidal neovascularization. Invest Ophthalmol Vis Sci 2008 1.06
54 Asymmetric dimethylarginine correlates with measures of disease severity, major adverse cardiovascular events and all-cause mortality in patients with peripheral arterial disease. Vasc Med 2010 1.06
55 Dimethylarginine dimethylaminohydrolase promotes endothelial repair after vascular injury. J Am Coll Cardiol 2007 1.04
56 Genetics of peripheral artery disease. Circulation 2012 1.03
57 Increased nitric oxide availability attenuates high fat diet metabolic alterations and gene expression associated with insulin resistance. Cardiovasc Diabetol 2011 1.03
58 Sex differences in the prevalence of peripheral artery disease in patients undergoing coronary catheterization. Vasc Med 2010 1.03
59 Usefulness of the addition of beta-2-microglobulin, cystatin C and C-reactive protein to an established risk factors model to improve mortality risk prediction in patients undergoing coronary angiography. Am J Cardiol 2013 1.02
60 Oxidative stress-dependent cyclooxygenase-2-derived prostaglandin f(2α) impairs endothelial function in renovascular hypertensive rats. Antioxid Redox Signal 2011 1.01
61 A biomarker panel for peripheral arterial disease. Vasc Med 2008 1.01
62 Developmental endothelial locus-1 (Del-1), a novel angiogenic protein: its role in ischemia. Circulation 2004 1.01
63 Psychophysiological and cortisol responses to psychological stress in depressed and nondepressed older men and women with elevated cardiovascular disease risk. Psychosom Med 2006 1.00
64 DDAH says NO to ADMA. Arterioscler Thromb Vasc Biol 2011 1.00
65 Insulin resistance: potential role of the endogenous nitric oxide synthase inhibitor ADMA. Vasc Med 2005 0.97
66 Tissue-specific downregulation of dimethylarginine dimethylaminohydrolase in hyperhomocysteinemia. Am J Physiol Heart Circ Physiol 2008 0.97
67 nAChRs mediate human embryonic stem cell-derived endothelial cells: proliferation, apoptosis, and angiogenesis. PLoS One 2009 0.97
68 Cell-free production of transducible transcription factors for nuclear reprogramming. Biotechnol Bioeng 2009 0.96
69 Does leptin cause vascular disease? Circulation 2002 0.96
70 Phase II clinical research design in cardiology: learning the right lessons too well: observations and recommendations from the Cardiovascular Cell Therapy Research Network (CCTRN). Circulation 2013 0.95
71 Discordant effects of a soluble VEGF receptor on wound healing and angiogenesis. Gene Ther 2004 0.95
72 State-of-the-Art Methods for Evaluation of Angiogenesis and Tissue Vascularization: A Scientific Statement From the American Heart Association. Circ Res 2015 0.94
73 Cholinergic modulation of angiogenesis: role of the 7 nicotinic acetylcholine receptor. J Cell Biochem 2009 0.94
74 Walking impairment questionnaire improves mortality risk prediction models in a high-risk cohort independent of peripheral arterial disease status. Circ Cardiovasc Qual Outcomes 2013 0.94
75 Endothelial cells derived from nuclear reprogramming. Circ Res 2012 0.93
76 Homocysteine impairs coronary microvascular dilator function in humans. J Am Coll Cardiol 2002 0.93
77 Task force 11: training in vascular medicine and peripheral vascular catheter-based interventions endorsed by the Society for Cardiovascular Angiography and Interventions and the Society for Vascular Medicine. J Am Coll Cardiol 2008 0.92
78 Frequent occult infection with Cytomegalovirus in cardiac transplant recipients despite antiviral prophylaxis. J Clin Microbiol 2007 0.92
79 PPARδ activation protects endothelial function in diabetic mice. Diabetes 2012 0.92
80 Overexpression of dimethylarginine dimethylaminohydrolase protects against cerebral vascular effects of hyperhomocysteinemia. Circ Res 2009 0.91
81 Role of nitric oxide signaling in endothelial differentiation of embryonic stem cells. Stem Cells Dev 2010 0.91
82 Homocysteine-induced vascular dysregulation is mediated by the NMDA receptor. Vasc Med 2005 0.91
83 Development of pluripotent stem cells for vascular therapy. Vascul Pharmacol 2012 0.90
84 The modulation of endothelial cell morphology, function, and survival using anisotropic nanofibrillar collagen scaffolds. Biomaterials 2013 0.90
85 Asymmetric dimethylarginine (ADMA): a key regulator of nitric oxide synthase. Atheroscler Suppl 2003 0.90
86 Transcriptional activation of hypoxia-inducible factor-1 (HIF-1) in myeloid cells promotes angiogenesis through VEGF and S100A8. Proc Natl Acad Sci U S A 2014 0.90
87 Suboptimal intensity of risk factor modification in PAD. Vasc Med 2005 0.90
88 Aligned nanofibrillar collagen regulates endothelial organization and migration. Regen Med 2012 0.89
89 Identification and classification of acute cardiac rejection by intragraft transcriptional profiling. Circulation 2011 0.89
90 Concurrent generation of functional smooth muscle and endothelial cells via a vascular progenitor. Stem Cells Transl Med 2013 0.89
91 Changes in coronary arterial dimensions early after cardiac transplantation. Transplantation 2007 0.89
92 Bioluminescence imaging of stem cell-based therapeutics for vascular regeneration. Theranostics 2012 0.88
93 Isoflavones improve vascular reactivity in post-menopausal women with hypercholesterolemia. Vasc Med 2004 0.88
94 The role of nicotine in the pathogenesis of atherosclerosis. Atherosclerosis 2011 0.88
95 Asymmetric dimethyl-arginine and coronary artery calcification in young adults entering middle age: the CARDIA Study. Eur J Cardiovasc Prev Rehabil 2007 0.87
96 Chronic exposure to nicotine impairs cholinergic angiogenesis. Vasc Med 2009 0.87
97 Nicotine and pathological angiogenesis. Life Sci 2012 0.87
98 Chemotaxis of human induced pluripotent stem cell-derived endothelial cells. Am J Transl Res 2013 0.87
99 Postgraduate training in vascular medicine: proposed requirements and standards. Vasc Med 2003 0.87
100 DDAH: a target for vascular therapy? Vasc Med 2010 0.86
101 Two decades of progress in vascular medicine. Am J Med 2011 0.86
102 Development of a dimethylarginine dimethylaminohydrolase (DDAH) assay for high-throughput chemical screening. J Biomol Screen 2012 0.86
103 Vascular compliance versus flow-mediated vasodilation: correlation with cardiovascular risk factors. Vasc Med 2005 0.86
104 Assessing endothelial vasodilator function with the Endo-PAT 2000. J Vis Exp 2010 0.86
105 NOS inhibition accelerates atherogenesis: reversal by exercise. Am J Physiol Heart Circ Physiol 2003 0.85
106 A matrix micropatterning platform for cell localization and stem cell fate determination. Acta Biomater 2010 0.85
107 Cardiac allograft vasculopathy and dysregulation of the NO synthase pathway. Arterioscler Thromb Vasc Biol 2003 0.84
108 Two cardiovascular risk factors in one? Homocysteine and its relation to glomerular filtration rate. A meta-analysis of 41 studies with 27,000 participants. Kidney Blood Press Res 2008 0.84
109 Does improving mood in depressed patients alter factors that may affect cardiovascular disease risk? J Psychiatr Res 2009 0.84
110 A critical role for thioredoxin-interacting protein in diabetes-related impairment of angiogenesis. Diabetes 2013 0.84
111 ADMA: an emerging cardiovascular risk factor. Vasc Med 2005 0.84
112 MicroRNA and mechanisms of impaired angiogenesis in diabetes mellitus. Circulation 2011 0.84
113 Extensive characterization of the human DDAH1 transgenic mice. Pharmacol Res 2009 0.84
114 Spatial patterning of endothelium modulates cell morphology, adhesiveness and transcriptional signature. Biomaterials 2013 0.83
115 A pilot study of L-arginine supplementation on functional capacity in peripheral arterial disease. Vasc Med 2005 0.83
116 FXR agonist INT-747 upregulates DDAH expression and enhances insulin sensitivity in high-salt fed Dahl rats. PLoS One 2013 0.83
117 Identification of Bone Marrow Cell Subpopulations Associated With Improved Functional Outcomes in Patients With Chronic Left Ventricular Dysfunction: An Embedded Cohort Evaluation of the FOCUS-CCTRN Trial. Cell Transplant 2015 0.83
118 Lymphangiogenesis: a potential new therapy for lymphedema? Circulation 2012 0.81
119 Cerebral autoregulation in the vertebral and middle cerebral arteries during combine head upright tilt and lower body negative pressure in healthy humans. Conf Proc IEEE Eng Med Biol Soc 2010 0.81
120 Cholinergic activation of hematopoietic stem cells: role in tobacco-related disease? Vasc Med 2010 0.81
121 Hypercholesterolemia impairs exercise capacity in mice. Vasc Med 2009 0.81
122 A novel and potent inhibitor of dimethylarginine dimethylaminohydrolase: a modulator of cardiovascular nitric oxide. J Pharmacol Exp Ther 2013 0.81
123 Clinical trials of adult stem cell therapy for peripheral artery disease. Methodist Debakey Cardiovasc J 2013 0.80
124 Topical mecamylamine for diabetic macular edema. Am J Ophthalmol 2010 0.79
125 A novel bioluminescent tumor model of human renal cancer cell lines: an in vitro and in vivo characterization. J Urol 2007 0.79
126 Capillary electrophoretic and micellar electrokinetic separations of asymmetric dimethyl-L-arginine and structurally related amino acids: quantitation in human plasma. J Sep Sci 2004 0.79
127 Asymmetric dimethylarginine and cardiac allograft vasculopathy progression: modulation by sirolimus. Transplantation 2008 0.79
128 Genetic determinants of the ankle-brachial index: a meta-analysis of a cardiovascular candidate gene 50K SNP panel in the candidate gene association resource (CARe) consortium. Atherosclerosis 2012 0.79
129 Effect of local delivery of L-arginine on in-stent restenosis in humans. Am J Cardiol 2002 0.78
130 Randomized trial of AT-1015 for treatment of intermittent claudication. A novel 5-hydroxytryptamine antagonist with no evidence of efficacy. Vasc Med 2004 0.78
131 Solubility partner IF2 Domain I enables high yield synthesis of transducible transcription factors in Escherichia coli. Protein Expr Purif 2011 0.78
132 Predictors of physical function in patients with peripherial arterial disease and claudication. Prog Cardiovasc Nurs 2004 0.78
133 Arginine metabolism, pulmonary hypertension, and sickle cell disease. JAMA 2005 0.77
134 Short polymers of arginine rapidly translocate into vascular cells: effects on nitric oxide synthesis. Circ J 2002 0.77
135 NOx and ADMA changes with focal ischemia, amelioration with the chaperonin GroEL. Neurosci Lett 2007 0.77
136 Relationship of asymmetric dimethylarginine and homocysteine to vascular aging in systemic lupus erythematosus patients. Arthritis Rheum 2010 0.77
137 Gender differences in perception of PAD: a pilot study. Vasc Med 2003 0.77
138 The combination of 9p21.3 genotype and biomarker profile improves a peripheral artery disease risk prediction model. Vasc Med 2013 0.77
139 Should we measure asymmetric dimethylarginine in patients with coronary artery disease? Clin Chem 2007 0.77
140 Effects of dimethylarginine dimethylaminohydrolase-1 overexpression on the response of the pulmonary vasculature to hypoxia. Am J Respir Cell Mol Biol 2013 0.76
141 Exercise patterns and cardiovascular fitness of patients with peripheral arterial disease. J Vasc Nurs 2004 0.76
142 Induced pluripotent stem cells: how they will change the practice of cardiovascular medicine. Methodist Debakey Cardiovasc J 2013 0.76
143 Flow-responsive remodeling after angioplasty is enhanced by high cholesterol diet. Prevention with pyrrolidine dithiocarbamate. Atherosclerosis 2003 0.76
144 Imaging vascular nicotine receptors: a new window onto vascular disease. JACC Cardiovasc Imaging 2012 0.76
145 Response to letters regarding article, "unexpected effect of proton pump inhibitors: elevation of the cardiovascular risk factor asymmetric dimethylarginine". Circulation 2014 0.76
146 Abnormal cardiovascular response to exercise in patients with peripheral arterial disease: Implications for management. J Vasc Nurs 2005 0.75
147 A peculiar result and a fanciful hypothesis regarding L-arginine. Arterioscler Thromb Vasc Biol 2003 0.75
148 Therapeutic transdifferentiation: can we generate cardiac tissue rather than scar after myocardial injury? Methodist Debakey Cardiovasc J 2013 0.75
149 Critical determinants of limb ischemia. J Am Coll Cardiol 2008 0.75
150 Characterization of a fluorescent probe for imaging nitric oxide. J Vasc Res 2013 0.75
151 Pharmacovigilance using Clinical Text. AMIA Jt Summits Transl Sci Proc 2013 0.75
152 Letter by Stuehlinger et al regarding article, "Metabolic profiling of arginine and nitric oxide pathways predicts hemodynamic abnormalities and mortality in patients with cardiogenic shock after acute myocardial infarction". Circulation 2008 0.75
153 Endovascular correction of cerebrovenous anomalies in multiple sclerosis: a retrospective review of an uncontrolled case series. Vasc Med 2012 0.75
154 Letter by Kielstein et al regarding article, "Renal function as a predictor of outcome in a broad spectrum of patients with heart failure". Circulation 2006 0.75
155 Re: The American "board" of vascular medicine: questions and concerns. J Vasc Interv Radiol 2006 0.75
156 In Memoriam of John T. Shepherd, MD, DSc. Circulation 2012 0.75
157 Telomerase mRNA Reverses Senescence in Progeria Cells. J Am Coll Cardiol 2017 0.75
158 [Coronary allograft vasculopathy: pathophysiological interaction between the immune system, infections and metabolic syndrome]. G Ital Cardiol (Rome) 2007 0.75
159 Regenerative medicine in cardiovascular disease: introduction. Methodist Debakey Cardiovasc J 2013 0.75