| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
(E)-N-(3,3-Diphenyl-allyl-idene)-4-nitro-aniline.
|
Acta Crystallogr Sect E Struct Rep Online
|
2012
|
2.05
|
|
2
|
(E)-N-(3,3-Diphenyl-allyl-idene)-3-nitro-aniline.
|
Acta Crystallogr Sect E Struct Rep Online
|
2012
|
2.03
|
|
3
|
(E)-2,2'-[3-(2-Nitro-phen-yl)prop-2-ene-1,1-di-yl]bis-(3-hy-droxy-5,5-dimethyl-cyclo-hex-2-en-1-one).
|
Acta Crystallogr Sect E Struct Rep Online
|
2011
|
2.01
|
|
4
|
2,2-[(E)-3,3-Diphenyl-prop-2-ene-1,1-di-yl]bis-(3-hy-droxy-cyclo-hex-2-en-1-one).
|
Acta Crystallogr Sect E Struct Rep Online
|
2011
|
1.56
|
|
5
|
3-Hy-droxy-2-[(2E)-1-(2-hy-droxy-6-oxocyclo-hex-1-en-1-yl)-3-(2-meth-oxy-phen-yl)prop-2-en-1-yl]cyclo-hex-2-en-1-one.
|
Acta Crystallogr Sect E Struct Rep Online
|
2011
|
1.54
|
|
6
|
2,2'-[(E)-3-(4-Nitro-phen-yl)prop-2-ene-1,1-di-yl]bis-(3-hy-droxy-5,5-dimethyl-cyclo-hex-2-en-1-one).
|
Acta Crystallogr Sect E Struct Rep Online
|
2012
|
1.28
|
|
7
|
9-[(E)-2-(2-Meth-oxy-phen-yl)ethen-yl]-3,4,5,6,7,9-hexa-hydro-2H-xanthene-1,8-dione.
|
Acta Crystallogr Sect E Struct Rep Online
|
2012
|
1.23
|
|
8
|
(E)-2,2'-[3-(4-Fluoro-phen-yl)prop-2-ene-1,1-di-yl]bis-(3-hy-droxy-5,5-dimethyl-cyclo-hex-2-en-1-one).
|
Acta Crystallogr Sect E Struct Rep Online
|
2013
|
1.16
|
|
9
|
(E)-3,3,6,6-Tetra-methyl-9-(2-nitro-styr-yl)-3,4,5,6,7,9-hexa-hydro-1H-xanthene-1,8(2H)-dione.
|
Acta Crystallogr Sect E Struct Rep Online
|
2012
|
1.11
|
|
10
|
(E)-N-[(E)-3-(4-Nitro-phen-yl)allyl-idene]naphthalen-1-amine.
|
Acta Crystallogr Sect E Struct Rep Online
|
2013
|
1.07
|
|
11
|
5- And 6-exocyclic products, cis-2,3,5-trisubstituted tetrahydrofurans, and cis-2,3,6-trisubstituted tetrahydropyrans via Prins-type cyclization.
|
J Org Chem
|
2008
|
1.06
|
|
12
|
(E)-9-(4-Chloro-styr-yl)-3,4,5,6,7,9-hexa-hydro-2H-xanthene-1,8-dione.
|
Acta Crystallogr Sect E Struct Rep Online
|
2012
|
1.06
|
|
13
|
(E)-2,2'-[3-(2-Nitro-phen-yl)prop-2-ene-1,1-di-yl]bis-(3-hy-droxy-cyclo-hex-2-en-1-one).
|
Acta Crystallogr Sect E Struct Rep Online
|
2011
|
1.02
|
|
14
|
Synthesis and biological evaluation of novel T-type Ca2+ channel blockers.
|
Bioorg Med Chem
|
2004
|
0.98
|
|
15
|
Novel GSK-3beta inhibitors from sequential virtual screening.
|
Bioorg Med Chem
|
2007
|
0.92
|
|
16
|
(E)-2,2'-[3-(4-Chloro-phen-yl)prop-2-ene-1,1-di-yl]bis-(3-hy-droxy-5,5-di-methyl-cyclo-hex-2-en-1-one).
|
Acta Crystallogr Sect E Struct Rep Online
|
2013
|
0.92
|
|
17
|
(E)-9-(4-Fluoro-styr-yl)-3,3,6,6-tetra-methyl-3,4,5,6,7,9-hexa-hydro-2H-xanthene-1,8-dione.
|
Acta Crystallogr Sect E Struct Rep Online
|
2013
|
0.92
|
|
18
|
5-Exocyclic products, 2,3,5-trisubstituted tetrahydrofurans via Prins-type cyclization.
|
Org Lett
|
2006
|
0.92
|
|
19
|
(E)-N-(3,3-Di-phenyl-allyl-idene)naph-thal-en-1-amine.
|
Acta Crystallogr Sect E Struct Rep Online
|
2013
|
0.91
|
|
20
|
(E)-N-(3,3-Di-phenyl-allyl-idene)-2-(tri-fluoro-meth-yl)aniline.
|
Acta Crystallogr Sect E Struct Rep Online
|
2013
|
0.90
|
|
21
|
Highly stereoselective synthesis of 2,5-disubstituted 3-vinylidene tetetrahydrofurans via Prins-type cyclization.
|
Org Lett
|
2005
|
0.88
|
|
22
|
Novel quinazolinone derivatives as 5-HT7 receptor ligands.
|
Bioorg Med Chem
|
2007
|
0.86
|
|
23
|
IKKbeta inhibitors identification part II: ligand and structure-based virtual screening.
|
Bioorg Med Chem
|
2010
|
0.85
|
|
24
|
Synthesis of 3,4-dimethylidene oxacycles through Prins-type cyclization of allenylmethylsilanes.
|
Chem Asian J
|
2011
|
0.84
|
|
25
|
A concise synthesis of tetrabenazine: an intramolecular aza-Prins-type cyclization via oxidative C-H activation.
|
Org Lett
|
2011
|
0.82
|
|
26
|
Novel pyrimidoazepine analogs as serotonin 5-HT(2A) and 5-HT(2C) receptor ligands for the treatment of obesity.
|
Eur J Med Chem
|
2013
|
0.81
|
|
27
|
In silico renal clearance model using classical Volsurf approach.
|
J Chem Inf Model
|
2006
|
0.80
|
|
28
|
IKKβ inhibitor identification: a multi-filter driven novel scaffold.
|
BMC Bioinformatics
|
2010
|
0.80
|
|
29
|
First pharmacophoric hypothesis for T-type calcium channel blockers.
|
Bioorg Med Chem
|
2004
|
0.80
|
|
30
|
IKKbeta inhibitors identification part I: homology model assisted structure based virtual screening.
|
Bioorg Med Chem
|
2009
|
0.80
|
|
31
|
Facile synthesis and biological evaluation of 3,3-diphenylpropanoyl piperazines as T-type calcium channel blockers.
|
Bioorg Med Chem Lett
|
2010
|
0.80
|
|
32
|
New serotonin 5-HT(6) ligands from common feature pharmacophore hypotheses.
|
J Chem Inf Model
|
2007
|
0.79
|
|
33
|
Discovery of piperidinyl aminopyrimidine derivatives as IKK-2 inhibitors.
|
Bioorg Med Chem Lett
|
2011
|
0.79
|
|
34
|
Synthesis and biological evaluation of 1,4-diazepane derivatives as T-type calcium channel blockers.
|
Bioorg Med Chem Lett
|
2010
|
0.79
|
|
35
|
Identification of novel serotonin 2C receptor ligands by sequential virtual screening.
|
Bioorg Med Chem
|
2009
|
0.79
|
|
36
|
Classification of dopamine, serotonin, and dual antagonists by decision trees.
|
Bioorg Med Chem
|
2006
|
0.78
|
|
37
|
3D QSAR pharmacophore model based on diverse IKKβ inhibitors.
|
J Mol Model
|
2010
|
0.78
|
|
38
|
Pharmacological actions of a novel and selective dopamine D3 receptor antagonist, KCH-1110.
|
Pharmacol Res
|
2003
|
0.78
|
|
39
|
Novel T-type calcium channel blockers: dioxoquinazoline carboxamide derivatives.
|
Bioorg Med Chem
|
2006
|
0.77
|
|
40
|
3D pharmacophore based virtual screening of T-type calcium channel blockers.
|
Bioorg Med Chem
|
2006
|
0.77
|
|
41
|
Synthesis and biological evaluation of oxazole derivatives as T-type calcium channel blockers.
|
Bioorg Med Chem Lett
|
2010
|
0.77
|
|
42
|
Quinazolindione derivatives as potent 5-HT3A receptor antagonists.
|
Bioorg Med Chem
|
2009
|
0.77
|
|
43
|
QSAR studies on piperazinylalkylisoxazole analogues selectively acting on dopamine D3 receptor by HQSAR and CoMFA.
|
Bioorg Med Chem
|
2003
|
0.76
|
|
44
|
CoMFA and CoMSIA 3D QSAR analysis on N1-arylsulfonylindole compounds as 5-HT6 antagonists.
|
Bioorg Med Chem
|
2004
|
0.76
|
|
45
|
Identification of structural determinants of ligand selectivity in 5-HT₂ receptor subtypes on the basis of protein-ligand interactions.
|
J Mol Graph Model
|
2012
|
0.76
|
|
46
|
Identification of novel antitubercular compounds through hybrid virtual screening approach.
|
Bioorg Med Chem
|
2010
|
0.76
|
|
47
|
Synthesis and biological evaluation of 2,4-diaminoquinazoline derivatives as novel heat shock protein 90 inhibitors.
|
Bioorg Med Chem Lett
|
2011
|
0.76
|
|
48
|
[2-(4-Chloro-phen-yl)-5-phenyl-oxolan-3-yl](cyclo-penten-yl)methanone.
|
Acta Crystallogr Sect E Struct Rep Online
|
2011
|
0.75
|
|
49
|
Synthesis and evaluation of oxime derivatives as modulators for amyloid beta-induced mitochondrial dysfunction.
|
Eur J Med Chem
|
2012
|
0.75
|
|
50
|
9-[(E)-2-(4-Chloro-phen-yl)ethen-yl]-3,3,6,6-tetra-methyl-2,3,4,5,6,7,8,9-octa-hydro-1H-xanthene-1,8-dione.
|
Acta Crystallogr Sect E Struct Rep Online
|
2013
|
0.75
|
|
51
|
Synthesis and biological evaluation of 2-substituted quinoline 6-carboxamides as potential mGluR1 antagonists for the treatment of neuropathic pain.
|
Chem Pharm Bull (Tokyo)
|
2014
|
0.75
|
|
52
|
Stereocontrolled synthesis of oxaspirobicycles via Prins-pinacol annulation.
|
Org Lett
|
2009
|
0.75
|
|
53
|
Synthesis and in vitro activity of new methylenepiperidinyl and methylenepyrrolidinyl oxazolidinone antibacterial agents.
|
Bioorg Med Chem Lett
|
2003
|
0.75
|
|
54
|
Volsurf analysis of carbapenem antibiotics.
|
Bioorg Med Chem
|
2005
|
0.75
|
|
55
|
Synthesis and in vitro activity of novel isoxazolyl tetrahydropyridinyl oxazolidinone antibacterial agents.
|
Bioorg Med Chem Lett
|
2003
|
0.75
|
|
56
|
5-HT₂c receptor selectivity and structure-activity relationship of N-methyl-N-(1-methylpiperidin-4-yl)benzenesulfonamide analogs.
|
Bioorg Med Chem Lett
|
2011
|
0.75
|
|
57
|
Hologram quantitative structure activity relationship studies on 5-HT6 antagonists.
|
Bioorg Med Chem
|
2004
|
0.75
|
|
58
|
Synthesis and biological evaluation of 2-(arylethynyl)quinoline derivatives as mGluR5 antagonists for the treatment of neuropathic pain.
|
Bioorg Med Chem Lett
|
2012
|
0.75
|
|
59
|
Efficient synthesis of mibefradil analogues: an insight into in vitro stability.
|
Org Biomol Chem
|
2014
|
0.75
|
|
60
|
Structure based design of heat shock protein 90 inhibitors acting as anticancer agents.
|
Bioorg Med Chem
|
2011
|
0.75
|
|
61
|
3D QSAR studies on T-type calcium channel blockers using CoMFA and CoMSIA.
|
Bioorg Med Chem
|
2004
|
0.75
|
|
62
|
Classification of dopamine antagonists using functional feature hypothesis and topological descriptors.
|
Bioorg Med Chem
|
2005
|
0.75
|
|
63
|
Design and synthesis of a piperazinylalkylisoxazole library for subtype selective dopamine receptor ligands.
|
Bioorg Med Chem Lett
|
2002
|
0.75
|
|
64
|
Facile diverted synthesis of pyrrolidinyl triazoles using organotrifluoroborate: discovery of potential mPTP blockers.
|
Org Biomol Chem
|
2014
|
0.75
|
|
65
|
Comparative QSAR studies on peptide deformylase inhibitors.
|
J Mol Model
|
2007
|
0.75
|
|
66
|
Computational approach to the identification of novel Aurora-A inhibitors.
|
Bioorg Med Chem
|
2010
|
0.75
|
|
67
|
Design, synthesis, and biological evaluation of 1,3-dioxoisoindoline-5-carboxamide derivatives as T-type calcium channel blockers.
|
Bioorg Med Chem Lett
|
2006
|
0.75
|
|
68
|
Intermolecular double Prins-type cyclization: a facile and efficient synthesis of 1,6-dioxecanes.
|
Angew Chem Int Ed Engl
|
2009
|
0.75
|