Published in BMC Genomics on May 25, 2010
Is the MC1R variant p.R160W associated with Parkinson's? Ann Neurol (2015) 1.25
Follow-up of loci from the International Genomics of Alzheimer's Disease Project identifies TRIP4 as a novel susceptibility gene. Transl Psychiatry (2014) 1.07
Replication of MAPT and SNCA, but not PARK16-18, as susceptibility genes for Parkinson's disease. Mov Disord (2011) 1.01
The Growing Importance of CNVs: New Insights for Detection and Clinical Interpretation. Front Genet (2013) 0.96
Unravelling the hidden ancestry of American admixed populations. Nat Commun (2015) 0.90
Genome-wide association study of multiple sclerosis confirms a novel locus at 5p13.1. PLoS One (2012) 0.90
WWOX gene is associated with HDL cholesterol and triglyceride levels. BMC Med Genet (2010) 0.88
ATP5H/KCTD2 locus is associated with Alzheimer's disease risk. Mol Psychiatry (2013) 0.86
HGDP and HapMap analysis by Ancestry Mapper reveals local and global population relationships. PLoS One (2012) 0.84
Towns with extremely low mortality due to ischemic heart disease in Spain. BMC Public Health (2012) 0.83
A colorectal cancer susceptibility new variant at 4q26 in the Spanish population identified by genome-wide association analysis. PLoS One (2014) 0.80
Genetic analysis of candidate SNPs for metabolic syndrome in obstructive sleep apnea (OSA). Gene (2013) 0.79
Association analysis of urotensin II gene (UTS2) and flanking regions with biochemical parameters related to insulin resistance. PLoS One (2011) 0.79
Assessing the genetic influence of ancient sociopolitical structure: micro-differentiation patterns in the population of Asturias (Northern Spain). PLoS One (2012) 0.76
Involvement of ANXA5 and ILKAP in susceptibility to malignant melanoma. PLoS One (2014) 0.76
Attention deficit hyperactivity disorder: genetic association study in a cohort of Spanish children. Behav Brain Funct (2016) 0.75
No evidence of firstly acquired acute hepatitis C virus infection outbreak among HIV-infected patients from Southern Spain: a multicentric retrospective study from 2000-2014. BMC Infect Dis (2016) 0.75
PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet (2007) 209.92
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature (2007) 144.95
Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics (2004) 125.23
A haplotype map of the human genome. Nature (2005) 105.70
A second generation human haplotype map of over 3.1 million SNPs. Nature (2007) 85.39
The International HapMap Project. Nature (2003) 73.65
Global variation in copy number in the human genome. Nature (2006) 57.50
Detecting the number of clusters of individuals using the software STRUCTURE: a simulation study. Mol Ecol (2005) 55.64
The structure of haplotype blocks in the human genome. Science (2002) 50.88
Population structure and eigenanalysis. PLoS Genet (2006) 37.21
Galaxy: a platform for interactive large-scale genome analysis. Genome Res (2005) 35.75
A high-resolution survey of deletion polymorphism in the human genome. Nat Genet (2005) 16.99
Association mapping in structured populations. Am J Hum Genet (2000) 16.79
The effects of human population structure on large genetic association studies. Nat Genet (2004) 14.88
Genes mirror geography within Europe. Nature (2008) 14.23
Segmental duplications and copy-number variation in the human genome. Am J Hum Genet (2005) 13.33
Discerning the ancestry of European Americans in genetic association studies. PLoS Genet (2007) 7.81
GRR: graphical representation of relationship errors. Bioinformatics (2001) 6.09
Genome-wide detection of human copy number variations using high-density DNA oligonucleotide arrays. Genome Res (2006) 5.97
An Icelandic example of the impact of population structure on association studies. Nat Genet (2004) 5.53
Mutations in genes encoding ribonuclease H2 subunits cause Aicardi-Goutières syndrome and mimic congenital viral brain infection. Nat Genet (2006) 5.26
Correlation between genetic and geographic structure in Europe. Curr Biol (2008) 5.02
Investigation of the fine structure of European populations with applications to disease association studies. Eur J Hum Genet (2008) 3.65
Genetic structure of Europeans: a view from the North-East. PLoS One (2009) 3.46
Geographical structure and differential natural selection among North European populations. Genome Res (2009) 3.03
Germ-line DNA copy number variation frequencies in a large North American population. Hum Genet (2007) 2.94
Global distribution of genomic diversity underscores rich complex history of continental human populations. Genome Res (2009) 2.76
[Prevalence of the metabolic syndrome (ATP-III criteria). Population-based study of rural and urban areas in the Spanish province of Segovia]. Med Clin (Barc) (2005) 1.69
FstSNP-HapMap3: a database of SNPs with high population differentiation for HapMap3. Bioinformation (2008) 1.12
Genetics. 17q21.31: not your average genomic address. Science (2008) 1.02
Molecular evolution of the human chromosome 15 pericentromeric region. Cytogenet Genome Res (2005) 1.01
Copy-number variations and human disease. Am J Hum Genet (2007) 0.78
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet (2010) 17.89
Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways. Diabetes (2010) 4.07
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet (2012) 3.21
Antithrombotic drugs and risk of hemorrhagic stroke in the general population. Neurology (2013) 2.85
Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes. Diabetes (2011) 2.21
Nonsteroidal antiinflammatory drugs and the risk of myocardial infarction in the general population. Circulation (2004) 1.87
A genome-wide association search for type 2 diabetes genes in African Americans. PLoS One (2012) 1.72
[Prevalence of the metabolic syndrome (ATP-III criteria). Population-based study of rural and urban areas in the Spanish province of Segovia]. Med Clin (Barc) (2005) 1.69
Effect of antisecretory drugs and nitrates on the risk of ulcer bleeding associated with nonsteroidal anti-inflammatory drugs, antiplatelet agents, and anticoagulants. Am J Gastroenterol (2007) 1.67
A method for detecting epistasis in genome-wide studies using case-control multi-locus association analysis. BMC Genomics (2008) 1.64
Variations in the promoter region of the glutaminase gene and the development of hepatic encephalopathy in patients with cirrhosis: a cohort study. Ann Intern Med (2010) 1.60
Hormone therapy and cerebrovascular events: a population-based nested case-control study. Menopause (2006) 1.43
Incidence of hemorrhagic stroke in the general population: validation of data from The Health Improvement Network. Pharmacoepidemiol Drug Saf (2012) 1.34
Investigation of c9orf72 in 4 neurodegenerative disorders. Arch Neurol (2012) 1.32
The FTO obesity gene. Genotyping and gene expression analysis in morbidly obese patients. Obes Surg (2008) 1.31
CCR5 expression influences the progression of human breast cancer in a p53-dependent manner. J Exp Med (2003) 1.25
Serum circulating microRNA profiling for identification of potential type 2 diabetes and obesity biomarkers. PLoS One (2013) 1.24
Protein farnesyltransferase in embryogenesis, adult homeostasis, and tumor development. Cancer Cell (2005) 1.23
The CALHM1 P86L polymorphism is a genetic modifier of age at onset in Alzheimer's disease: a meta-analysis study. J Alzheimers Dis (2010) 1.19
An entropy test for single-locus genetic association analysis. BMC Genet (2010) 1.15
Identification of the first recurrent PAR1 deletion in Léri-Weill dyschondrosteosis and idiopathic short stature reveals the presence of a novel SHOX enhancer. J Med Genet (2012) 1.12
Inverse association between nonsteroidal anti-inflammatory drugs and prostate cancer. Cancer Epidemiol Biomarkers Prev (2004) 1.11
Propranolol for infantile hemangiomas. Pediatr Dermatol (2011) 1.11
Lipodystrophy and metabolic syndrome in HIV-infected patients treated with antiretroviral therapy. Metabolism (2006) 1.10
Long-term use of non-steroidal anti-inflammatory drugs and the risk of myocardial infarction in the general population. BMC Med (2005) 1.08
Influence of the Toll-like receptor 9 1635A/G polymorphism on the CD4 count, HIV viral load, and clinical progression. J Acquir Immune Defic Syndr (2008) 1.08
Sex and body mass index specific regulation of blood pressure by CYP19A1 gene variants. Hypertension (2007) 1.06
Genes and hepatitis C: susceptibility, fibrosis progression and response to treatment. Liver Int (2011) 1.06
Role of follicle-stimulating hormone receptor Ser680Asn polymorphism in the efficacy of follicle-stimulating hormone. Fertil Steril (2003) 1.05
A longitudinal follow-up of 550 mild cognitive impairment patients: evidence for large conversion to dementia rates and detection of major risk factors involved. J Alzheimers Dis (2013) 1.05
NSAID use selectively increases the risk of non-fatal myocardial infarction: a systematic review of randomised trials and observational studies. PLoS One (2011) 1.04
Analysis of HLA class I expression in progressing and regressing metastatic melanoma lesions after immunotherapy. Immunogenetics (2008) 1.03
CALHM1 P86L polymorphism is associated with late-onset Alzheimer's disease in a recessive model. J Alzheimers Dis (2010) 1.03
GOLPH2 gene markers are not associated with Alzheimer's disease in a sample of the Spanish population. J Alzheimers Dis (2009) 1.02
An SNP in the adiponectin gene is associated with decreased serum adiponectin levels and risk for impaired glucose tolerance. Obes Res (2005) 1.02
Geographic variations of the International Diabetes Federation and the National Cholesterol Education Program-Adult Treatment Panel III definitions of the metabolic syndrome in nondiabetic subjects. Diabetes Care (2006) 1.02
Which obesity index best explains prevalence differences in type 2 diabetes mellitus? Obesity (Silver Spring) (2007) 1.00
Central adiposity determines prevalence differences of the metabolic syndrome. Obes Res (2003) 0.98
The membrane-spanning 4-domains, subfamily A (MS4A) gene cluster contains a common variant associated with Alzheimer's disease. Genome Med (2011) 0.98
Comment: CAPN10 alleles are associated with polycystic ovary syndrome. J Clin Endocrinol Metab (2002) 0.97
Lipid accumulation product: a powerful marker of metabolic syndrome in healthy population. Eur J Endocrinol (2011) 0.97
The association between leptin and left ventricular hypertrophy: a population-based cross-sectional study. J Hypertens (2003) 0.96
Human vitamin K-dependent GAS6: gene structure, allelic variation, and association with stroke. Hum Mutat (2004) 0.96
Ability of lipid accumulation product to identify metabolic syndrome in healthy men from Buenos Aires. Diabetes Care (2009) 0.95
Bone morphogenetic protein 15 (BMP15) alleles predict over-response to recombinant follicle stimulation hormone and iatrogenic ovarian hyperstimulation syndrome (OHSS). Pharmacogenet Genomics (2006) 0.94
Variant rs9939609 in the FTO gene is associated with obesity in an adult population from Spain. Clin Endocrinol (Oxf) (2008) 0.94
Common variants of the liver fatty acid binding protein gene influence the risk of type 2 diabetes and insulin resistance in Spanish population. PLoS One (2012) 0.92
Regressing and progressing metastatic lesions: resistance to immunotherapy is predetermined by irreversible HLA class I antigen alterations. Cancer Immunol Immunother (2008) 0.91
[The Epidat program]. Rev Panam Salud Publica (2010) 0.91
New diseases derived or associated with the tight junction. Arch Med Res (2007) 0.91
Identification of genetic factors associated with susceptibility to angiotensin-converting enzyme inhibitors-induced cough. Pharmacogenet Genomics (2011) 0.90
Activation of PKR causes amyloid ß-peptide accumulation via de-repression of BACE1 expression. PLoS One (2011) 0.90
Human controlled ovarian hyperstimulation outcome is a polygenic trait. Pharmacogenetics (2004) 0.90
Multiple sclerosis risk variant HLA-DRB1*1501 associates with high expression of DRB1 gene in different human populations. PLoS One (2012) 0.90
Genome-wide association study of multiple sclerosis confirms a novel locus at 5p13.1. PLoS One (2012) 0.90