Published in PLoS Genet on December 01, 2006
A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer. Nat Genet (2007) 22.96
A HapMap harvest of insights into the genetics of common disease. J Clin Invest (2008) 18.31
Fast model-based estimation of ancestry in unrelated individuals. Genome Res (2009) 15.63
Variance component model to account for sample structure in genome-wide association studies. Nat Genet (2010) 15.52
Genes mirror geography within Europe. Nature (2008) 14.23
Practical aspects of imputation-driven meta-analysis of genome-wide association studies. Hum Mol Genet (2008) 13.26
IL28B is associated with response to chronic hepatitis C interferon-alpha and ribavirin therapy. Nat Genet (2009) 13.03
Efficient control of population structure in model organism association mapping. Genetics (2008) 12.32
Inferring weak population structure with the assistance of sample group information. Mol Ecol Resour (2009) 10.81
The genetic structure and history of Africans and African Americans. Science (2009) 10.65
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease. Nat Genet (2013) 9.46
Reconstructing Indian population history. Nature (2009) 9.28
Complete Khoisan and Bantu genomes from southern Africa. Nature (2010) 9.06
Estimation of significance thresholds for genomewide association scans. Genet Epidemiol (2008) 8.88
Interpreting principal component analyses of spatial population genetic variation. Nat Genet (2008) 8.49
New approaches to population stratification in genome-wide association studies. Nat Rev Genet (2010) 7.97
Discerning the ancestry of European Americans in genetic association studies. PLoS Genet (2007) 7.81
Discriminant analysis of principal components: a new method for the analysis of genetically structured populations. BMC Genet (2010) 7.67
Genome-wide survey of SNP variation uncovers the genetic structure of cattle breeds. Science (2009) 7.64
Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemia. Nat Genet (2010) 7.08
Simultaneous analysis of all SNPs in genome-wide and re-sequencing association studies. PLoS Genet (2008) 6.66
Analysis and application of European genetic substructure using 300 K SNP information. PLoS Genet (2008) 6.42
Sensitive detection of chromosomal segments of distinct ancestry in admixed populations. PLoS Genet (2009) 6.36
Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions. Nat Genet (2010) 5.52
Optimal unified approach for rare-variant association testing with application to small-sample case-control whole-exome sequencing studies. Am J Hum Genet (2012) 5.48
Genome-wide patterns of population structure and admixture in West Africans and African Americans. Proc Natl Acad Sci U S A (2009) 5.39
Genome-wide association study identifies variants in the ABO locus associated with susceptibility to pancreatic cancer. Nat Genet (2009) 5.14
Variants in the CDKN2B and RTEL1 regions are associated with high-grade glioma susceptibility. Nat Genet (2009) 5.13
Ancient admixture in human history. Genetics (2012) 4.99
Genetic variation and population structure in native Americans. PLoS Genet (2007) 4.87
Inference of population structure using dense haplotype data. PLoS Genet (2012) 4.87
Inference of population splits and mixtures from genome-wide allele frequency data. PLoS Genet (2012) 4.85
Resequencing 50 accessions of cultivated and wild rice yields markers for identifying agronomically important genes. Nat Biotechnol (2011) 4.84
Quality control and quality assurance in genotypic data for genome-wide association studies. Genet Epidemiol (2010) 4.83
The Population Reference Sample, POPRES: a resource for population, disease, and pharmacological genetics research. Am J Hum Genet (2008) 4.79
A genomewide admixture map for Latino populations. Am J Hum Genet (2007) 4.71
A genome-wide association study identifies novel alleles associated with hair color and skin pigmentation. PLoS Genet (2008) 4.57
Double digest RADseq: an inexpensive method for de novo SNP discovery and genotyping in model and non-model species. PLoS One (2012) 4.52
Genomewide association for schizophrenia in the CATIE study: results of stage 1. Mol Psychiatry (2008) 4.14
A genealogical interpretation of principal components analysis. PLoS Genet (2009) 4.12
Actionable, pathogenic incidental findings in 1,000 participants' exomes. Am J Hum Genet (2013) 4.06
On the use of general control samples for genome-wide association studies: genetic matching highlights causal variants. Am J Hum Genet (2008) 3.95
A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci. Nat Genet (2010) 3.93
Genome-wide association study identifies three loci associated with melanoma risk. Nat Genet (2009) 3.89
LD Score regression distinguishes confounding from polygenicity in genome-wide association studies. Nat Genet (2015) 3.82
Chromosome 6p22 locus associated with clinically aggressive neuroblastoma. N Engl J Med (2008) 3.80
Ancient human genomes suggest three ancestral populations for present-day Europeans. Nature (2014) 3.80
Data quality control in genetic case-control association studies. Nat Protoc (2010) 3.68
Reconciling the analysis of IBD and IBS in complex trait studies. Nat Rev Genet (2010) 3.62
Chromosome 9p21 in sporadic amyotrophic lateral sclerosis in the UK and seven other countries: a genome-wide association study. Lancet Neurol (2010) 3.61
Key susceptibility locus for nonsyndromic cleft lip with or without cleft palate on chromosome 8q24. Nat Genet (2009) 3.58
Genome-wide association study implicates a chromosome 12 risk locus for late-onset Alzheimer disease. Am J Hum Genet (2009) 3.54
A SUMOylation-defective MITF germline mutation predisposes to melanoma and renal carcinoma. Nature (2011) 3.53
Denisova admixture and the first modern human dispersals into Southeast Asia and Oceania. Am J Hum Genet (2011) 3.53
Reconstructing Native American population history. Nature (2012) 3.49
Genetic variants and risk of lung cancer in never smokers: a genome-wide association study. Lancet Oncol (2010) 3.49
A simple genetic architecture underlies morphological variation in dogs. PLoS Biol (2010) 3.46
Recalibrating Equus evolution using the genome sequence of an early Middle Pleistocene horse. Nature (2013) 3.45
Population substructure and control selection in genome-wide association studies. PLoS One (2008) 3.44
The geography of recent genetic ancestry across Europe. PLoS Biol (2013) 3.44
Genomic analyses identify distinct patterns of selection in domesticated pigs and Tibetan wild boars. Nat Genet (2013) 3.41
The genome-wide structure of the Jewish people. Nature (2010) 3.37
Genetic variants at 2q24 are associated with susceptibility to type 2 diabetes. Hum Mol Genet (2010) 3.24
Colloquium paper: genome-wide patterns of population structure and admixture among Hispanic/Latino populations. Proc Natl Acad Sci U S A (2010) 3.20
Genome-wide analysis of the world's sheep breeds reveals high levels of historic mixture and strong recent selection. PLoS Biol (2012) 3.19
Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis. Nat Genet (2013) 3.17
Japanese population structure, based on SNP genotypes from 7003 individuals compared to other ethnic groups: effects on population-based association studies. Am J Hum Genet (2008) 3.12
Identifying signatures of natural selection in Tibetan and Andean populations using dense genome scan data. PLoS Genet (2010) 3.11
A genetic atlas of human admixture history. Science (2014) 3.09
Correction for hidden confounders in the genetic analysis of gene expression. Proc Natl Acad Sci U S A (2010) 3.08
Pitfalls of predicting complex traits from SNPs. Nat Rev Genet (2013) 3.06
Long-range LD can confound genome scans in admixed populations. Am J Hum Genet (2008) 3.06
Discovering genetic ancestry using spectral graph theory. Genet Epidemiol (2010) 3.03
Geographical structure and differential natural selection among North European populations. Genome Res (2009) 3.03
Genome-wide associations and functional genomic studies of musculoskeletal adverse events in women receiving aromatase inhibitors. J Clin Oncol (2010) 3.02
A unified association analysis approach for family and unrelated samples correcting for stratification. Am J Hum Genet (2008) 3.00
Genomic dissection of population substructure of Han Chinese and its implication in association studies. Am J Hum Genet (2009) 2.93
Genetic structure and domestication history of the grape. Proc Natl Acad Sci U S A (2011) 2.89
The history of African gene flow into Southern Europeans, Levantines, and Jews. PLoS Genet (2011) 2.81
The genome-wide patterns of variation expose significant substructure in a founder population. Am J Hum Genet (2008) 2.79
Genome-wide patterns of genetic variation in worldwide Arabidopsis thaliana accessions from the RegMap panel. Nat Genet (2012) 2.78
Global distribution of genomic diversity underscores rich complex history of continental human populations. Genome Res (2009) 2.76
Upper Palaeolithic Siberian genome reveals dual ancestry of Native Americans. Nature (2013) 2.75
Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis. Nat Genet (2013) 2.60
A genomewide association study of skin pigmentation in a South Asian population. Am J Hum Genet (2007) 2.58
Population genomics of Bronze Age Eurasia. Nature (2015) 2.58
Sequence variants in SLC16A11 are a common risk factor for type 2 diabetes in Mexico. Nature (2013) 2.57
Ascertainment biases in SNP chips affect measures of population divergence. Mol Biol Evol (2010) 2.56
Exome array analysis identifies new loci and low-frequency variants influencing insulin processing and secretion. Nat Genet (2012) 2.55
Abraham's children in the genome era: major Jewish diaspora populations comprise distinct genetic clusters with shared Middle Eastern Ancestry. Am J Hum Genet (2010) 2.54
A genome-wide association study on African-ancestry populations for asthma. J Allergy Clin Immunol (2009) 2.53
Genetic signals of origin, spread, and introgression in a large sample of maize landraces. Proc Natl Acad Sci U S A (2010) 2.52
Inferring admixture histories of human populations using linkage disequilibrium. Genetics (2013) 2.51
Quality control procedures for genome-wide association studies. Curr Protoc Hum Genet (2011) 2.48
Common variations in BARD1 influence susceptibility to high-risk neuroblastoma. Nat Genet (2009) 2.47
Complex population structure in African village dogs and its implications for inferring dog domestication history. Proc Natl Acad Sci U S A (2009) 2.42
Persistent host markers in pandemic and H5N1 influenza viruses. J Virol (2007) 2.42
PCA-correlated SNPs for structure identification in worldwide human populations. PLoS Genet (2007) 2.36
Analysis of genomic diversity in Mexican Mestizo populations to develop genomic medicine in Mexico. Proc Natl Acad Sci U S A (2009) 2.32
Population genetic inference from genomic sequence variation. Genome Res (2010) 2.29
Inference of population structure using multilocus genotype data. Genetics (2000) 147.76
Principal components analysis corrects for stratification in genome-wide association studies. Nat Genet (2006) 115.71
A haplotype map of the human genome. Nature (2005) 105.70
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Inference of population structure using multilocus genotype data: linked loci and correlated allele frequencies. Genetics (2003) 53.11
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High resolution of human evolutionary trees with polymorphic microsatellites. Nature (1994) 28.48
Population structure, differential bias and genomic control in a large-scale, case-control association study. Nat Genet (2005) 25.34
High-resolution haplotype structure in the human genome. Nat Genet (2001) 20.51
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Assessing the impact of population stratification on genetic association studies. Nat Genet (2004) 16.28
Blocks of limited haplotype diversity revealed by high-resolution scanning of human chromosome 21. Science (2001) 15.54
Calibrating a coalescent simulation of human genome sequence variation. Genome Res (2005) 15.04
The effects of human population structure on large genetic association studies. Nat Genet (2004) 14.88
Methods for high-density admixture mapping of disease genes. Am J Hum Genet (2004) 12.02
A high-density admixture map for disease gene discovery in african americans. Am J Hum Genet (2004) 10.87
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Support from the relationship of genetic and geographic distance in human populations for a serial founder effect originating in Africa. Proc Natl Acad Sci U S A (2005) 10.22
The application of molecular genetic approaches to the study of human evolution. Nat Genet (2003) 7.44
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An Icelandic example of the impact of population structure on association studies. Nat Genet (2004) 5.53
Standardized subsets of the HGDP-CEPH Human Genome Diversity Cell Line Panel, accounting for atypical and duplicated samples and pairs of close relatives. Ann Hum Genet (2006) 5.42
Evidence for gradients of human genetic diversity within and among continents. Genome Res (2004) 4.70
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Population structure in the Mediterranean basin: a Y chromosome perspective. Ann Hum Genet (2006) 2.28
Ethiopia: between Sub-Saharan Africa and western Eurasia. Ann Hum Genet (2005) 1.98
Principal components analysis corrects for stratification in genome-wide association studies. Nat Genet (2006) 115.71
Integrating common and rare genetic variation in diverse human populations. Nature (2010) 32.30
Assessing the impact of population stratification on genetic association studies. Nat Genet (2004) 16.28
Calibrating a coalescent simulation of human genome sequence variation. Genome Res (2005) 15.04
Multiple regions within 8q24 independently affect risk for prostate cancer. Nat Genet (2007) 14.37
Methods for high-density admixture mapping of disease genes. Am J Hum Genet (2004) 12.02
A high-density admixture map for disease gene discovery in african americans. Am J Hum Genet (2004) 10.87
Admixture mapping identifies 8q24 as a prostate cancer risk locus in African-American men. Proc Natl Acad Sci U S A (2006) 10.32
MYH9 is associated with nondiabetic end-stage renal disease in African Americans. Nat Genet (2008) 9.50
Reconstructing Indian population history. Nature (2009) 9.28
Two independent alleles at 6q23 associated with risk of rheumatoid arthritis. Nat Genet (2007) 8.74
New approaches to population stratification in genome-wide association studies. Nat Rev Genet (2010) 7.97
A high-coverage genome sequence from an archaic Denisovan individual. Science (2012) 7.89
Comparison of fine-scale recombination rates in humans and chimpanzees. Science (2005) 7.86
Discerning the ancestry of European Americans in genetic association studies. PLoS Genet (2007) 7.81
Concept, design and implementation of a cardiovascular gene-centric 50 k SNP array for large-scale genomic association studies. PLoS One (2008) 7.16
A common genetic risk factor for colorectal and prostate cancer. Nat Genet (2007) 7.11
Genetic evidence for complex speciation of humans and chimpanzees. Nature (2006) 6.66
Measurement of the human allele frequency spectrum demonstrates greater genetic drift in East Asians than in Europeans. Nat Genet (2007) 6.63
Sensitive detection of chromosomal segments of distinct ancestry in admixed populations. PLoS Genet (2009) 6.36
Ancient admixture in human history. Genetics (2012) 4.99
A genomewide admixture map for Latino populations. Am J Hum Genet (2007) 4.71
Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies. Lancet (2012) 4.63
Exome sequencing and the genetic basis of complex traits. Nat Genet (2012) 4.11
Functional enhancers at the gene-poor 8q24 cancer-linked locus. PLoS Genet (2009) 3.59
Testing for ancient admixture between closely related populations. Mol Biol Evol (2011) 3.56
Reconstructing Native American population history. Nature (2012) 3.49
The landscape of recombination in African Americans. Nature (2011) 3.06
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Admixture mapping of white cell count: genetic locus responsible for lower white blood cell count in the Health ABC and Jackson Heart studies. Am J Hum Genet (2008) 3.06
Great ape genetic diversity and population history. Nature (2013) 2.95
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The history of African gene flow into Southern Europeans, Levantines, and Jews. PLoS Genet (2011) 2.81
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Inferring admixture histories of human populations using linkage disequilibrium. Genetics (2013) 2.51
Extremely low-coverage sequencing and imputation increases power for genome-wide association studies. Nat Genet (2012) 2.50
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A direct characterization of human mutation based on microsatellites. Nat Genet (2012) 2.38
The role of the CD58 locus in multiple sclerosis. Proc Natl Acad Sci U S A (2009) 2.38
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Ancient DNA reveals key stages in the formation of central European mitochondrial genetic diversity. Science (2013) 2.23
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Accelerated genetic drift on chromosome X during the human dispersal out of Africa. Nat Genet (2008) 2.22
Using extended genealogy to estimate components of heritability for 23 quantitative and dichotomous traits. PLoS Genet (2013) 2.19
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Genome-wide association study of ancestry-specific TB risk in the South African Coloured population. Hum Mol Genet (2013) 1.25
An admixture scan in 1,484 African American women with breast cancer. Cancer Epidemiol Biomarkers Prev (2009) 1.22
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