PubRank

Stefano Rivella

Author PubWeight™ 51.04‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Ineffective erythropoiesis in beta-thalassemia is characterized by increased iron absorption mediated by down-regulation of hepcidin and up-regulation of ferroportin. Blood 2007 2.52
2 Hepcidin as a therapeutic tool to limit iron overload and improve anemia in β-thalassemic mice. J Clin Invest 2010 2.18
3 Macrophages support pathological erythropoiesis in polycythemia vera and β-thalassemia. Nat Med 2013 1.89
4 β-thalassemia: a model for elucidating the dynamic regulation of ineffective erythropoiesis and iron metabolism. Blood 2011 1.81
5 Decreased differentiation of erythroid cells exacerbates ineffective erythropoiesis in beta-thalassemia. Blood 2008 1.72
6 Unexpected expression of alpha- and beta-globin in mesencephalic dopaminergic neurons and glial cells. Proc Natl Acad Sci U S A 2009 1.64
7 Decreased hepcidin mRNA expression in thalassemic mice. Br J Haematol 2004 1.61
8 Reducing TMPRSS6 ameliorates hemochromatosis and β-thalassemia in mice. J Clin Invest 2013 1.44
9 Downregulation of hepcidin and haemojuvelin expression in the hepatocyte cell-line HepG2 induced by thalassaemic sera. Br J Haematol 2006 1.31
10 Successful treatment of murine beta-thalassemia intermedia by transfer of the human beta-globin gene. Blood 2002 1.29
11 mRNA expression of iron regulatory genes in beta-thalassemia intermedia and beta-thalassemia major mouse models. Am J Hematol 2006 1.22
12 Non-transfusion-dependent thalassemias. Haematologica 2013 1.21
13 Distinct roles for hepcidin and interleukin-6 in the recovery from anemia in mice injected with heat-killed Brucella abortus. Blood 2013 1.15
14 Anemia, ineffective erythropoiesis, and hepcidin: interacting factors in abnormal iron metabolism leading to iron overload in β-thalassemia. Hematol Oncol Clin North Am 2010 1.14
15 Myeloid cell-derived hypoxia-inducible factor attenuates inflammation in unilateral ureteral obstruction-induced kidney injury. J Immunol 2012 1.09
16 The murine growth differentiation factor 15 is not essential for systemic iron homeostasis in phlebotomized mice. Haematologica 2012 1.08
17 Therapeutic options for patients with severe beta-thalassemia: the need for globin gene therapy. Hum Gene Ther 2007 1.03
18 Role of iron in inducing oxidative stress in thalassemia: Can it be prevented by inhibition of absorption and by antioxidants? Ann N Y Acad Sci 2005 1.03
19 Therapeutic hemoglobin levels after gene transfer in β-thalassemia mice and in hematopoietic cells of β-thalassemia and sickle cells disease patients. PLoS One 2012 0.99
20 Enhanced erythropoiesis in Hfe-KO mice indicates a role for Hfe in the modulation of erythroid iron homeostasis. Blood 2010 0.99
21 Intestinal HIF2α promotes tissue-iron accumulation in disorders of iron overload with anemia. Proc Natl Acad Sci U S A 2013 0.98
22 beta-Thalassemia: HiJAKing Ineffective Erythropoiesis and Iron Overload. Adv Hematol 2010 0.98
23 Regulation of iron absorption in hemoglobinopathies. Curr Mol Med 2008 0.97
24 Gene therapy for hemoglobinopathies: progress and challenges. Transl Res 2013 0.96
25 Iron metabolism and ineffective erythropoiesis in beta-thalassemia mouse models. Ann N Y Acad Sci 2010 0.93
26 Decreased hepcidin expression in murine β-thalassemia is associated with suppression of Bmp/Smad signaling. Blood 2012 0.93
27 Production of beta-globin and adult hemoglobin following G418 treatment of erythroid precursor cells from homozygous beta(0)39 thalassemia patients. Am J Hematol 2009 0.90
28 Exploring the role of hepcidin, an antimicrobial and iron regulatory peptide, in increased iron absorption in beta-thalassemia. Ann N Y Acad Sci 2005 0.88
29 A combined approach for β-thalassemia based on gene therapy-mediated adult hemoglobin (HbA) production and fetal hemoglobin (HbF) induction. Ann Hematol 2012 0.86
30 Gene therapy in thalassemia and hemoglobinopathies. Mediterr J Hematol Infect Dis 2009 0.86
31 Isocitrate ameliorates anemia by suppressing the erythroid iron restriction response. J Clin Invest 2013 0.85
32 FOXO3-mTOR metabolic cooperation in the regulation of erythroid cell maturation and homeostasis. Am J Hematol 2014 0.85
33 Development of K562 cell clones expressing beta-globin mRNA carrying the beta039 thalassaemia mutation for the screening of correctors of stop-codon mutations. Biotechnol Appl Biochem 2009 0.84
34 Id1 represses osteoclast-dependent transcription and affects bone formation and hematopoiesis. PLoS One 2009 0.84
35 A preclinical approach for gene therapy of beta-thalassemia. Ann N Y Acad Sci 2010 0.84
36 Prospects for a hepcidin mimic to treat β-thalassemia and hemochromatosis. Expert Rev Hematol 2011 0.84
37 Progress toward the genetic treatment of the beta-thalassemias. Ann N Y Acad Sci 2005 0.84
38 FGF-23 is a negative regulator of prenatal and postnatal erythropoiesis. J Biol Chem 2014 0.83
39 Therapeutic globin gene delivery using lentiviral vectors. Curr Opin Mol Ther 2002 0.83
40 Iron and reactive oxygen species: friends or foes of cancer cells? Antioxid Redox Signal 2013 0.82
41 Hepcidin and Hfe in iron overload in beta-thalassemia. Ann N Y Acad Sci 2010 0.81
42 Analysis of alpha hemoglobin stabilizing protein overexpression in murine β-thalassemia. Am J Hematol 2010 0.81
43 Combining gene therapy and fetal hemoglobin induction for treatment of β-thalassemia. Expert Rev Hematol 2013 0.79
44 Changes in bone microarchitecture and biomechanical properties in the th3 thalassemia mouse are associated with decreased bone turnover and occur during the period of bone accrual. Calcif Tissue Int 2010 0.79
45 Globin gene transfer for treatment of the beta-thalassemias and sickle cell disease. Best Pract Res Clin Haematol 2004 0.78
46 Protective role of calreticulin in HFE hemochromatosis. Free Radic Biol Med 2007 0.78
47 In vivo gene transfer strategies to achieve partial correction of von Willebrand disease. Hum Gene Ther 2012 0.75